S Besse



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    Besse S, Boucher F, Linguet G, Riou L, de Leiris J, Riou B, et al. Intramyocardial protein therapy with vascular endothelial growth factor (VEGF-165) induces functional angiogenesis in rat senescent myocardium. J Physiol Pharmacol. 2010;61:651-61 pubmed
    ..VEGF-165 protein therapy was able to induce in vitro and in vivo angiogenesis during aging. In 24 mo hearts, in vivo angiogenesis was functional, sustained and comparable to neovascularization observed in 3 mo hearts. ..
  2. Besse S, Comte R, Frechault S, Courty J, Joël d, Delbe J. Pleiotrophin promotes capillary-like sprouting from senescent aortic rings. Cytokine. 2013;62:44-7 pubmed publisher
    ..PTN is able to induce ex vivo angiogenesis during aging and might be a new promising therapy to induce neovascularization in aged tissues as well as after age-associated cardiac, hindlimb or cerebral ischemia. ..
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    Huet E, Gabison E, Vallee B, Mougenot N, Linguet G, Riou B, et al. Deletion of extracellular matrix metalloproteinase inducer/CD147 induces altered cardiac extracellular matrix remodeling in aging mice. J Physiol Pharmacol. 2015;66:355-66 pubmed
  4. Launay T, Momken I, Carreira S, Mougenot N, Zhou X, de Koning L, et al. Acceleration-based training: A new mode of training in senescent rats improving performance and left ventricular and muscle functions. Exp Gerontol. 2017;95:71-76 pubmed publisher
    ..This acceleration-based training is not time-consuming and may be adaptable for athletes, the elderly or chronic disease patients in order to improve strength, oxidative capacity, and quality of life. ..