30,000 fewer heart attacks and strokes in North Carolina: a challenge to prioritize preventionAlain G Bertoni
Department of Epidemiology and Prevention, Wake Forest School of Medicine, Wake Forest University, Medical Center Blvd, Winston Salem NC 27157, USA
N C Med J 73:449-56. 2012
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Impact of the look AHEAD intervention on NT-pro brain natriuretic peptide in overweight and obese adults with diabetesAlain G Bertoni
Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston Salem, NC, USA
Obesity (Silver Spring) 20:1511-8. 2012
..In conclusion, among overweight and obese persons with diabetes, an ILI that reduced weight was associated with an increased NT-proBNP...
A multilevel assessment of barriers to adoption of Dietary Approaches to Stop Hypertension (DASH) among African Americans of low socioeconomic statusAlain G Bertoni
Division of Public Health Sciences, Wake Forest University School of Medicine, USA
J Health Care Poor Underserved 22:1205-20. 2011
..We examined perceptions of Dietary Approaches to Stop Hypertension (DASH) and the food environment among African Americans (AA) with high blood pressure living in two low-income communities and objectively assessed local food outlets...
- The impact of obesity on cardiovascular disease risk factors and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis
Gregory L Burke
Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Arch Intern Med 168:928-35. 2008
..To assess the importance of the obesity epidemic on cardiovascular disease (CVD) risk, we determined the prevalence of obesity and the relationship of obesity to CVD risk factors and subclinical vascular disease...
- The effects of race and region on cardiovascular morbidity among elderly Americans with diabetes
Alain G Bertoni
Department of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
Diabetes Care 28:2620-5. 2005
..Because geographic region is known to influence the risk of CVD in the U.S., we sought to determine the effects of race and region on cardiovascular morbidity among elderly Americans with diabetes...
- Appropriateness of cholesterol management in primary care by sex and level of cardiovascular risk
Ann Hiott Barham
Department of Family and Community Medicine, Wake Forest University, School of Medicine, Winston Salem, NC 27157 1084, USA
Prev Cardiol 12:95-101. 2009
..The challenge facing implementation of ATP III guidelines is much greater for intermediate- and high-risk patients than for low-risk patients...
- Impact of a multifaceted intervention on cholesterol management in primary care practices: guideline adherence for heart health randomized trial
Alain G Bertoni
Division of Public Health Sciences, Department of Epidemiology and Prevention, Wake Forest University Baptist Medical Center, Medical Center Blvd, Winston Salem, NC 27157, USA
Arch Intern Med 169:678-86. 2009
..Physician adherence to National Cholesterol Education Program clinical practice guidelines has been poor...
- Modification of the effect of glycemic status on aortic distensibility by age in the multi-ethnic study of atherosclerosis
R Brandon Stacey
Wake Forest University Health Sciences, Cardiology Section, Winston Salem, NC 27157, USA
Hypertension 55:26-32. 2010
..However, age modified the effect of glucose status such that differences between the groups diminished with advancing age...
- Suboptimal control of glycemia, blood pressure, and LDL cholesterol in overweight adults with diabetes: the Look AHEAD Study
Alain G Bertoni
Division of Public Health Sciences, Department of Epidemiology and Prevention, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
J Diabetes Complications 22:1-9. 2008
..The characteristics associated with meeting goals for glycemia, blood pressure (BP), and low-density lipoprotein (LDL) cholesterol for participants with diabetes were examined...
- Diabetic cardiomyopathy and subclinical cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis (MESA)
Alain G Bertoni
Wake Forest University Health Sciences, Department of Public Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
Diabetes Care 29:588-94. 2006
..We examined whether diabetic cardiomyopathy is associated with subclinical atherosclerosis and if abnormalities are found with impaired fasting glucose (IFG)...
- Ethnic disparities: control of glycemia, blood pressure, and LDL cholesterol among US adults with type 2 diabetes
Julienne K Kirk
Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157 1084, USA
Ann Pharmacother 39:1489-501. 2005
..To examine ethnic disparities in the quality of diabetes care among adults with diabetes in the US through a systematic qualitative review...
- The association between physical activity and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis
Alain G Bertoni
Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157, USA
Am J Epidemiol 169:444-54. 2009
..These data suggest that walking pace is associated with less subclinical atherosclerosis; these associations may be mediated by cardiovascular disease risk factors...
- Predicted risk of coronary heart disease among persons with type 2 diabetes
Julienne K Kirk
Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Coron Artery Dis 18:595-600. 2007
..We evaluated whether there are racial/ethnic differences in predicted probability of CHD among persons with type 2 diabetes from the 1999-2002 National Health and Nutrition Examination Survey...
- Excess mortality related to diabetes mellitus in elderly Medicare beneficiaries
Alain G Bertoni
Department of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC, USA
Ann Epidemiol 14:362-7. 2004
..To determine whether diabetes remains an important contributor to mortality among the elderly...
- Insulin resistance, metabolic syndrome, and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis (MESA)
Alain G Bertoni
Department of Epidemiology and Prevention, Wake Forest University, Winston Salem, North Carolina, USA
Diabetes Care 30:2951-6. 2007
..To investigate the association of insulin resistance and clinically defined metabolic syndrome (MetS) with subclinical atherosclerosis and examine whether these relationships vary by race/ethnicity or sex...
- Electrocardiographic abnormalities associated with the metabolic syndrome and its components: the multi-ethnic study of atherosclerosis
Imo A Ebong
Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston Salem, North Carolina 27157, USA
Metab Syndr Relat Disord 10:92-7. 2012
..The association between metabolic syndrome and electrocardiographic (ECG) abnormalities is not well established...
- Value of recruitment strategies used in a primary care practice-based trial
Shellie D Ellis
Department of Outcomes Research, Duke Clinical Research Institute, Wake Forest University School of Medicine, Winston Salem, NC, U S A
Contemp Clin Trials 28:258-67. 2007
..However, yields are variable; and the approach can be costly and lead to biased, unrepresentative samples. We sought to explore the potential efficiency of alternative methods...
- Racial and ethnic disparities in cardiac catheterization for acute myocardial infarction in the United States, 1995--2001
Alain G Bertoni
Departments of Public Health Sciences and Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USA
J Natl Med Assoc 97:317-23. 2005
..for acute myocardial infarction (AMI) to determine whether disparities documented from the 1980s through mid-1990s persist, and evaluate whether patient and hospital characteristics are associated with any observed disparities..
- Quality of cholesterol screening and management with respect to the National Cholesterol Education's Third Adult Treatment Panel (ATPIII) guideline in primary care practices in North Carolina
Alain G Bertoni
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA
Am Heart J 152:785-92. 2006
..CONCLUSIONS: The median dyslipidemia screening rate met the recommendations. There remains a need to improve the management of dyslipidemia; in particular, there was a significant underprescription of lipid-lowering drugs...
- Inflammation and the incidence of type 2 diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA)
Alain G Bertoni
Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, North Carolina, USA
Diabetes Care 33:804-10. 2010
..Many studies have documented associations between inflammation and type 2 diabetes incidence. We assessed potential variability in this association in the major U.S. racial/ethnic groups...
- Control of blood pressure in North Carolina primary care: baseline data from the GLAD Heart Trial
Erica L Rosenberger
Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University School of Medicine, USA
N C Med J 69:441-6. 2008
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- Sex disparities in procedure use for acute myocardial infarction in the United States, 1995 to 2001
Alain G Bertoni
Department of Public Health Sciences, Winston Salem, NC, USA
Am Heart J 147:1054-60. 2004
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- Translating the Dietary Approaches to Stop Hypertension (DASH) diet for use in underresourced, urban African American communities, 2010
Melicia C Whitt-Glover
Gramercy Research Group, 500 W 4th St, Ste 203, Winston Salem, NC 27101, USA
Prev Chronic Dis 10:120088. 2013
..The objective of this pilot study was to test the feasibility of using a culturally modified version of DASH among African Americans in an underresourced community...
- Comparison of methods to measure heart size using noncontrast-enhanced computed tomography: correlation with left ventricular mass
Kurt R Daniel
Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Comput Assist Tomogr 32:934-41. 2008
..Left ventricular (LV) mass is a useful independent predictor of cardiovascular events. We sought to develop a new correlate of LV mass using noncontrast-enhanced cardiac computed tomography (NCE-CCT)...
- Correlates of coronary artery calcified plaque in blacks and whites with type 2 diabetes
Lynne E Wagenknecht
Division of Public Health Sciences, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
Ann Epidemiol 21:34-41. 2011
..To examine whether the relationship between cardiovascular disease risk factors and coronary artery calcification (CAC) is modified by race among those with diabetes...
- Hypertension treatment in the ambulatory setting: comparison by race and gender in a national survey
Denise E Bonds
Section of Epidemiology, Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Clin Hypertens (Greenwich) 6:223-8; quiz 229-30. 2004
..51; 95% CI, 1.20-1.91) and diuretics (OR, 1.37; 95% CI, 1.08-1.74). Low use of recommended therapies was found. Although variation by race was seen, it did not systematically favor groups associated with poor outcomes...
- Enhancing quality of heart failure care in managed Medicare and Medicaid in North Carolina: results of the North Carolina Achieving Cardiac Excellence (NC ACE) Project
David C Goff
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157 1063, USA
Am Heart J 150:717-24. 2005
..To evaluate an intervention to improve the quality of care of patients with heart failure in managed Medicare and Medicaid plans in North Carolina...
- Lifestyle change and mobility in obese adults with type 2 diabetes
W Jack Rejeski
Reynolda Campus, Wake Forest University, Winston Salem, NC 27109, USA
N Engl J Med 366:1209-17. 2012
..Adults with type 2 diabetes mellitus often have limitations in mobility that increase with age. An intensive lifestyle intervention that produces weight loss and improves fitness could slow the loss of mobility in such patients...
- A qualitative review of studies of diabetes preventive care among minority patients in the United States, 1993-2003
Julienne K Kirk
Department of Family and Community Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1084, USA
Am J Manag Care 11:349-60. 2005
..To review existing data to determine whether ethnic disparities exist for diabetes-related preventive care among adults in the United States...
- Participation in surgical oncology clinical trials: gender-, race/ethnicity-, and age-based disparities
John H Stewart
Department of General Surgery, Section on Surgical Oncology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Ann Surg Oncol 14:3328-34. 2007
..To characterize the representation of racial/ethnic minorities, women, and older persons among participants in surgical trials sponsored by the National Cancer Institute (NCI)...
- Dyslipidemia prevalence, treatment, and control in the Multi-Ethnic Study of Atherosclerosis (MESA): gender, ethnicity, and coronary artery calcium
David C Goff
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27101, USA
Circulation 113:647-56. 2006
..In addition, this report provides information about the presence of coronary artery calcium (CAC) across groups defined by risk and recommendations for the use of lipid-lowering drugs...
- Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study
Maggie C Y Ng
Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston Salem, North Carolina, USA
Diabetes 62:965-76. 2013
..The reduced and differential LD pattern in AfA compared with European and Asian populations may facilitate fine mapping of causal variants at loci shared across populations...
- Acute coronary syndrome national statistics: challenges in definitions
Alain G Bertoni
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
Am Heart J 149:1055-61. 2005
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- Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus
Jasmin Divers
Departments of Biostatistical Sciences, Wake Forest School of Medicine, Winston Salem, NC 27157 1053, USA
Circ Cardiovasc Genet 6:97-105. 2013
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- Heart failure prevalence, incidence, and mortality in the elderly with diabetes
Alain G Bertoni
Department of Public Health Science, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
Diabetes Care 27:699-703. 2004
..CONCLUSIONS: These data demonstrate alarmingly high prevalence, incidence, and mortality for heart failure in individuals with diabetes. Prevention of heart failure should be a research and clinical priority...
