Olivia Bermingham-McDonogh

Summary

Publications

  1. doi request reprint Regulated reprogramming in the regeneration of sensory receptor cells
    Olivia Bermingham-McDonogh
    Department of Biological Structure, Institute for Stem Cells and Regenerative Medicine, University of Washington, Seattle, WA 98195, USA
    Neuron 71:389-405. 2011
  2. pmc Delta/notch-like EGF-related receptor (DNER) is expressed in hair cells and neurons in the developing and adult mouse inner ear
    Byron H Hartman
    Department of Biological Structure, University of Washington, 1959 NE Pacific St, Box 357420, Seattle, WA 98195, USA
    J Assoc Res Otolaryngol 11:187-201. 2010
  3. ncbi request reprint Dll3 is expressed in developing hair cells in the mammalian cochlea
    Byron H Hartman
    Department of Biological Structure, University of Washington, Seattle, Washington 98195, USA
    Dev Dyn 236:2875-83. 2007
  4. pmc Expression patterns of FGF receptors in the developing mammalian cochlea
    Toshinori Hayashi
    Department of Biological Structure, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington 98109, USA
    Dev Dyn 239:1019-26. 2010
  5. pmc Expression of Prox1 during mouse cochlear development
    Olivia Bermingham-McDonogh
    Virginia Merrill Bloedel Hearing Research Center and Department of Otolaryngology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    J Comp Neurol 496:172-86. 2006
  6. ncbi request reprint Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti
    Toshinori Hayashi
    Virginia Merrill Bloedel Hearing Research Center, Department of Otolaryngology HNS, University of Washington, Seattle, Washington 98195, USA
    Dev Dyn 236:525-33. 2007
  7. pmc Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear
    Byron H Hartman
    Department of Biological Structure, University of Washington, Seattle, 98195, USA
    Proc Natl Acad Sci U S A 107:15792-7. 2010
  8. pmc Notch prosensory effects in the Mammalian cochlea are partially mediated by Fgf20
    Vidhya Munnamalai
    Department of Biological Structure, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington 98195, USA
    J Neurosci 32:12876-84. 2012
  9. pmc Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea
    Byron H Hartman
    Department of Biological Structure, University of Washington, Seattle, WA 98195, USA
    J Assoc Res Otolaryngol 10:321-40. 2009
  10. pmc Fgf20 is required for sensory epithelial specification in the developing cochlea
    Toshinori Hayashi
    Virginia Merrill Bloedel Hearing Research Center and Department of Biological Structure, University of Washington, Seattle, Washington 98195, USA
    J Neurosci 28:5991-9. 2008

Collaborators

Detail Information

Publications13

  1. doi request reprint Regulated reprogramming in the regeneration of sensory receptor cells
    Olivia Bermingham-McDonogh
    Department of Biological Structure, Institute for Stem Cells and Regenerative Medicine, University of Washington, Seattle, WA 98195, USA
    Neuron 71:389-405. 2011
    ..The field of regenerative medicine is still in its infancy, but new approaches using stem cells and reprogramming suggest ways in which the potential for regeneration may be restored in individuals suffering from sensory loss...
  2. pmc Delta/notch-like EGF-related receptor (DNER) is expressed in hair cells and neurons in the developing and adult mouse inner ear
    Byron H Hartman
    Department of Biological Structure, University of Washington, 1959 NE Pacific St, Box 357420, Seattle, WA 98195, USA
    J Assoc Res Otolaryngol 11:187-201. 2010
    ..We found no defects in expression of markers of supporting cells and glia or myelin, and no abnormalities in hair cells or neurons, suggesting that DNER plays a redundant role with other Notch ligands in cochlear development...
  3. ncbi request reprint Dll3 is expressed in developing hair cells in the mammalian cochlea
    Byron H Hartman
    Department of Biological Structure, University of Washington, Seattle, Washington 98195, USA
    Dev Dyn 236:2875-83. 2007
    ..Thus Dll3 may play a role in lateral inhibition similar to that of Dll1 and Jag2...
  4. pmc Expression patterns of FGF receptors in the developing mammalian cochlea
    Toshinori Hayashi
    Department of Biological Structure, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington 98109, USA
    Dev Dyn 239:1019-26. 2010
    ..We compare the receptor expression pattern to markers of the sensory domain (p27kip1) and the early hair cells (math1)...
  5. pmc Expression of Prox1 during mouse cochlear development
    Olivia Bermingham-McDonogh
    Virginia Merrill Bloedel Hearing Research Center and Department of Otolaryngology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    J Comp Neurol 496:172-86. 2006
    ..These studies form a baseline from which we can analyze the role of Prox1 in vertebrate sensory development...
  6. ncbi request reprint Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti
    Toshinori Hayashi
    Virginia Merrill Bloedel Hearing Research Center, Department of Otolaryngology HNS, University of Washington, Seattle, Washington 98195, USA
    Dev Dyn 236:525-33. 2007
    ..Thus, in addition to controlling the fate decision between pillar cells and Deiters' cells, we find that Fgfr3 also regulates the width of the sensory epithelium...
  7. pmc Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear
    Byron H Hartman
    Department of Biological Structure, University of Washington, Seattle, 98195, USA
    Proc Natl Acad Sci U S A 107:15792-7. 2010
    ..These results support a model where activation of Notch and propagation through lateral induction promote prosensory character in specific regions of the developing otocyst...
  8. pmc Notch prosensory effects in the Mammalian cochlea are partially mediated by Fgf20
    Vidhya Munnamalai
    Department of Biological Structure, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington 98195, USA
    J Neurosci 32:12876-84. 2012
    ..We hypothesized that Fgf20 plays a role in specification, amplification, or maintenance of Sox2 expression in prosensory progenitors of the developing mammalian cochlea...
  9. pmc Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea
    Byron H Hartman
    Department of Biological Structure, University of Washington, Seattle, WA 98195, USA
    J Assoc Res Otolaryngol 10:321-40. 2009
    ....
  10. pmc Fgf20 is required for sensory epithelial specification in the developing cochlea
    Toshinori Hayashi
    Virginia Merrill Bloedel Hearing Research Center and Department of Biological Structure, University of Washington, Seattle, Washington 98195, USA
    J Neurosci 28:5991-9. 2008
    ..Our results thus define the period of FGF-dependent sensory cell specification and the ligand that mediates this step in cochlear development...
  11. ncbi request reprint Hair cell regeneration: winging our way towards a sound future
    Olivia Bermingham-McDonogh
    Virginia Merrill Bloedel Hearing Research Center and Department of Otolaryngology HNS, University of Washington Medical School, Box 357923, Seattle, Washington 98195 7923, USA
    Curr Opin Neurobiol 13:119-26. 2003
    ..We examine some of the key recent findings in both birds and mammals...
  12. pmc A method for stabilizing RNA for transfection that allows control of expression duration
    Toshinori Hayashi
    Department of Biological Structure, Institute for Stem Cells and Regenerative Medicine, University of Washington School of Medicine, 815 Mercer Street, Seattle, WA 98109, USA
    Dev Dyn 239:2034-40. 2010
    ..We demonstrate this method in several cell and tissue types, including the mammalian cochlea, a tissue that has been difficult to transfect with other methods...
  13. pmc Acheate-scute like 1 (Ascl1) is required for normal delta-like (Dll) gene expression and notch signaling during retinal development
    Branden R Nelson
    Department of Biological Structure, School of Medicine, University of Washington, Seattle, Washington 98195, USA
    Dev Dyn 238:2163-78. 2009
    ..Thus, these results suggest a molecular mechanism whereby attenuated Notch levels coupled with reduced proneurogenic activity in progenitors leads to increased gliogenesis and decreased neurogenesis in the Ascl1-deficient retina...