S A Berger

Summary

Publications

  1. ncbi request reprint Phosphatidylinositol 3-kinase and Ca2+ influx dependence for ligand-stimulated internalization of the c-Kit receptor
    J L Gommerman
    Wellesley Hospital Research Institute and Department of Immunology, University of Toronto, Toronto, Ontario, Canada M4Y 1J3
    J Biol Chem 272:30519-25. 1997
  2. pmc c-KIT expression enhances the leukemogenic potential of 32D cells
    Q Hu
    Department of Medical Biophysics and Medicine, University of Toronto, Ontario, Canada
    J Clin Invest 95:2530-8. 1995
  3. ncbi request reprint Mast cells stimulated by membrane-bound, but not soluble, steel factor are dependent on phospholipase C activation
    N Z Trieselmann
    The Arthritis and Immune Disorder Research Centre, The University Health Network, Department of Immunology, University of Toronto, 620 University Ave, Suite 700, Toronto, Ontario M5G 2M9, Canada
    Cell Mol Life Sci 60:759-66. 2003

Collaborators

  • Y Xu
  • Q Hu
  • N Z Trieselmann
  • J L Gommerman
  • J Soboloff
  • R Rottapel

Detail Information

Publications3

  1. ncbi request reprint Phosphatidylinositol 3-kinase and Ca2+ influx dependence for ligand-stimulated internalization of the c-Kit receptor
    J L Gommerman
    Wellesley Hospital Research Institute and Department of Immunology, University of Toronto, Toronto, Ontario, Canada M4Y 1J3
    J Biol Chem 272:30519-25. 1997
    ..Our results demonstrate that both Ca2+ influx and PI3-kinase activity influence c-Kit endocytosis, and inhibition of these two signals disrupts the earliest stages of ligand-mediated internalization...
  2. pmc c-KIT expression enhances the leukemogenic potential of 32D cells
    Q Hu
    Department of Medical Biophysics and Medicine, University of Toronto, Ontario, Canada
    J Clin Invest 95:2530-8. 1995
    ..The model will be useful for studying the progression of leukemia in vivo and testing whether interruption of the interaction of Kit and KL can affect the growth of leukemic cells...
  3. ncbi request reprint Mast cells stimulated by membrane-bound, but not soluble, steel factor are dependent on phospholipase C activation
    N Z Trieselmann
    The Arthritis and Immune Disorder Research Centre, The University Health Network, Department of Immunology, University of Toronto, 620 University Ave, Suite 700, Toronto, Ontario M5G 2M9, Canada
    Cell Mol Life Sci 60:759-66. 2003
    ..However PKB/Akt, a kinase activated by PI3-kinase products, was phosphorylated following sSLF stimulation, but not with mSLF. Taken together, these studies demonstrate the importance of PLC activation by mSLF in supporting mast cells...