R H B Benedict

Summary

Publications

  1. ncbi Validity of the Beck Depression Inventory-Fast Screen in multiple sclerosis
    R H B Benedict
    Department of Neurology, State University of New York SUNY, Buffalo School of Medicine and Biomedical Sciences, Buffalo General Hospital, Buffalo, New York 14203, USA
    Mult Scler 9:393-6. 2003
  2. doi Psychometrics and normative data for the Multiple Sclerosis Functional Composite: replacing the PASAT with the Symbol Digit Modalities Test
    A S Drake
    Department of Neurology, State University of New York SUNY at Buffalo School of Medicine, Buffalo, NY, USA
    Mult Scler 16:228-37. 2010
  3. doi Regression-based norms improve the sensitivity of the National MS Society Consensus Neuropsychological Battery for Pediatric Multiple Sclerosis (NBPMS)
    A M Smerbeck
    Department of Neurology, State University of New York at Buffalo, NY, USA
    Clin Neuropsychol 26:985-1002. 2012
  4. ncbi Thalamic atrophy and cognition in multiple sclerosis
    M K Houtchens
    Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Partners MS Center, Boston, MA 02115, USA
    Neurology 69:1213-23. 2007
  5. doi Repeated assessment of neuropsychological deficits in multiple sclerosis using the Symbol Digit Modalities Test and the MS Neuropsychological Screening Questionnaire
    R H B Benedict
    School of Medicine, State University of New York at Buffalo, Buffalo, New York, USA
    Mult Scler 14:940-6. 2008
  6. doi No association between conventional brain MR imaging and chronic cerebrospinal venous insufficiency in multiple sclerosis
    R Zivadinov
    Buffalo Neuroimaging Analysis Center, Department of Neurology, School of Medicine and Biomedical Sciences, Buffalo, NY 14203, USA
    AJNR Am J Neuroradiol 33:1913-7. 2012
  7. doi Subjective fatigue is not associated with cognitive impairment in multiple sclerosis: cross-sectional and longitudinal analysis
    S A Morrow
    School of Medicine, The Jacobs Neurological Institute, State University of New York at Buffalo, Buffalo, New York 14203, USA
    Mult Scler 15:998-1005. 2009
  8. doi Memory impairment in multiple sclerosis: correlation with deep grey matter and mesial temporal atrophy
    R H B Benedict
    Jacobs Neurological Institute, Buffalo Neuroimaging Analysis Center, and Department of Neurology, State University of New York at Buffalo, New York 14203, USA
    J Neurol Neurosurg Psychiatry 80:201-6. 2009
  9. doi Regression-based pediatric norms for the brief visuospatial memory test: revised and the symbol digit modalities test
    A M Smerbeck
    Department of Neurology, State University of New York SUNY at Buffalo, Buffalo, NY, USA
    Clin Neuropsychol 25:402-12. 2011
  10. ncbi Interpreting patient/informant discrepancies of reported cognitive symptoms in MS
    D A Carone
    SUNY Buffalo School of Medicine and Buffalo General Hospital, Buffalo, New York 14203, USA
    J Int Neuropsychol Soc 11:574-83. 2005

Collaborators

Detail Information

Publications23

  1. ncbi Validity of the Beck Depression Inventory-Fast Screen in multiple sclerosis
    R H B Benedict
    Department of Neurology, State University of New York SUNY, Buffalo School of Medicine and Biomedical Sciences, Buffalo General Hospital, Buffalo, New York 14203, USA
    Mult Scler 9:393-6. 2003
    ..The BDI-FS may be useful in this regard although, to date, its validity in MS patients has not been assessed...
  2. doi Psychometrics and normative data for the Multiple Sclerosis Functional Composite: replacing the PASAT with the Symbol Digit Modalities Test
    A S Drake
    Department of Neurology, State University of New York SUNY at Buffalo School of Medicine, Buffalo, NY, USA
    Mult Scler 16:228-37. 2010
    ....
  3. doi Regression-based norms improve the sensitivity of the National MS Society Consensus Neuropsychological Battery for Pediatric Multiple Sclerosis (NBPMS)
    A M Smerbeck
    Department of Neurology, State University of New York at Buffalo, NY, USA
    Clin Neuropsychol 26:985-1002. 2012
    ..As in the case of adult MS, these results indicate that regression-based norms offer interpretive benefits over their manual-based counterparts...
  4. ncbi Thalamic atrophy and cognition in multiple sclerosis
    M K Houtchens
    Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, Partners MS Center, Boston, MA 02115, USA
    Neurology 69:1213-23. 2007
    ..In this study, we tested the hypothesis that thalamic volume is lower in MS than in normal subjects, and that thalamic atrophy in MS correlates with cognitive function...
  5. doi Repeated assessment of neuropsychological deficits in multiple sclerosis using the Symbol Digit Modalities Test and the MS Neuropsychological Screening Questionnaire
    R H B Benedict
    School of Medicine, State University of New York at Buffalo, Buffalo, New York, USA
    Mult Scler 14:940-6. 2008
    ....
  6. doi No association between conventional brain MR imaging and chronic cerebrospinal venous insufficiency in multiple sclerosis
    R Zivadinov
    Buffalo Neuroimaging Analysis Center, Department of Neurology, School of Medicine and Biomedical Sciences, Buffalo, NY 14203, USA
    AJNR Am J Neuroradiol 33:1913-7. 2012
    ..Therefore, this study determined the associations of CCSVI and conventional MR imaging outcomes in patients with MS and in HCs...
  7. doi Subjective fatigue is not associated with cognitive impairment in multiple sclerosis: cross-sectional and longitudinal analysis
    S A Morrow
    School of Medicine, The Jacobs Neurological Institute, State University of New York at Buffalo, Buffalo, New York 14203, USA
    Mult Scler 15:998-1005. 2009
    ..Studies in multiple sclerosis (MS) report conflicting conclusions regarding fatigue and cognition, which may partly be due to the use of small sample sizes and frequent reliance on a cross-sectional approach...
  8. doi Memory impairment in multiple sclerosis: correlation with deep grey matter and mesial temporal atrophy
    R H B Benedict
    Jacobs Neurological Institute, Buffalo Neuroimaging Analysis Center, and Department of Neurology, State University of New York at Buffalo, New York 14203, USA
    J Neurol Neurosurg Psychiatry 80:201-6. 2009
    ..However, the importance of mesial temporal lobe (MTL) atrophy in MS is largely untested and poorly understood. New structural imaging techniques permit volumetric measures of multiple regions within the MTL lobe and DGM...
  9. doi Regression-based pediatric norms for the brief visuospatial memory test: revised and the symbol digit modalities test
    A M Smerbeck
    Department of Neurology, State University of New York SUNY at Buffalo, Buffalo, NY, USA
    Clin Neuropsychol 25:402-12. 2011
    ..As the tests are validated in adult multiple sclerosis, they are likely to be useful in monitoring pediatric onset multiple sclerosis patients as they transition into adulthood...
  10. ncbi Interpreting patient/informant discrepancies of reported cognitive symptoms in MS
    D A Carone
    SUNY Buffalo School of Medicine and Buffalo General Hospital, Buffalo, New York 14203, USA
    J Int Neuropsychol Soc 11:574-83. 2005
    ..We conclude that patient/informant discrepancy scores on the MSNQ are associated with the aforementioned neuropsychiatric features, and that the MSNQ has potential utility for predicting euphoria and disinhibition syndromes in MS...
  11. ncbi Cognitive impairment is associated with subcortical magnetic resonance imaging grey matter T2 hypointensity in multiple sclerosis
    S D Brass
    Department of Neurology, Center for Neurological Imaging, Partners Multiple Sclerosis Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Mult Scler 12:437-44. 2006
    ..These data implicate a role for basal ganglia iron deposition in neuropsychological dysfunction...
  12. ncbi Screening for cognitive impairment in multiple sclerosis using the Symbol digit Modalities Test
    B A Parmenter
    Department of Neurology, Division of Developmental and Behavioral Neurosciences, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
    Mult Scler 13:52-7. 2007
    ..71, and negative predictive value (NPV) of 0.73. These results suggest that the effectiveness of the SDMT as a screen for cognitive impairment in MS is roughly equal to that of other psychometric and questionnaire methods...
  13. doi Effects of acute relapses on neuropsychological status in multiple sclerosis patients
    S A Morrow
    Jacobs Neurological Institute, State University of New York at Buffalo, Buffalo, NY, USA
    J Neurol 258:1603-8. 2011
    ..These results confirm the involvement of cognitive function during some MS relapses suggesting the SDMT or MSNQ can be used to identify transitory neuropsychological status changes and cognitive relapses...
  14. pmc Multicenter randomized clinical trial of donepezil for memory impairment in multiple sclerosis
    L B Krupp
    Department of Neurology, State University of New York at Stony Brook, Stony Brook, NY 11794 8121, USA
    Neurology 76:1500-7. 2011
    ..The goal of this study was to determine if memory would be improved by donepezil as compared to placebo in a multicenter, double-blind, randomized clinical trial (RCT)...
  15. doi Effects of l-amphetamine sulfate on cognitive function in multiple sclerosis patients
    R H B Benedict
    Dept of Neurology, State University of New York, Buffalo School of Medicine and the Jacobs, Neurological Institute, Buffalo, NY, USA
    J Neurol 255:848-52. 2008
    ..These preliminary findings show promise for the use of l-amphetamine for the symptomatic treatment of slowed mental processing in MS. Further placebo-controlled trials are needed to confirm these findings...
  16. ncbi Semi-automatic brain region extraction (SABRE) reveals superior cortical and deep gray matter atrophy in MS
    D A Carone
    Buffalo Neuroimaging Analysis Center, Buffalo, NY 14203, USA
    Neuroimage 29:505-14. 2006
    ..5%), and superior parietal (-6.1%) regions, with SP patients having lower volumes. Overall, atrophy in MS is diffuse and mostly related to GM loss particularly in deep GM and superior frontal-parietal regions...
  17. doi Visual-cognitive processing deficits in pediatric multiple sclerosis
    A M Smerbeck
    Department of Neurology, State University of New York, Buffalo, NY, USA
    Mult Scler 17:449-56. 2011
    ..This study investigates the sensitivity and validity in pediatric MS of two visual processing tests borrowed from the adult literature, the Brief Visuospatial Memory Test-Revised (BVMTR) and the Symbol Digit Modalities Test (SDMT)...
  18. pmc Neuropsychological impairment in systemic lupus erythematosus: a comparison with multiple sclerosis
    R H B Benedict
    Division of Cognitive and Behavioral Neurosciences, State University of New York at Buffalo, School of Medicine, Jacobs Neurological Institute, Buffalo General Hospital, Buffalo, NY 14203, USA
    Neuropsychol Rev 18:149-66. 2008
    ..There is less evidence for neurodegenerative changes in SLE, but patients are increasingly at risk for cerebrovascular disease. We conclude by offering some suggestions for future clinical and imaging research...
  19. doi Prevalence, sensitivity, and specificity of chronic cerebrospinal venous insufficiency in MS
    R Zivadinov
    Department of Neurology, School of Medicine and Biomedical Sciences Buffalo Neuroimaging Analysis Center, Buffalo, NY 14203, USA
    Neurology 77:138-44. 2011
    ..Chronic cerebrospinal venous insufficiency (CCSVI) was recently described in patients with multiple sclerosis (MS). A subject is considered CCSVI positive if ≥ 2 venous hemodynamic (VH) criteria are fulfilled...
  20. ncbi MRI T2 hypointensity of the dentate nucleus is related to ambulatory impairment in multiple sclerosis
    C W Tjoa
    Department of Neurology, University at Buffalo, State University of New York, Buffalo, NY, USA
    J Neurol Sci 234:17-24. 2005
    ..Ambulatory dysfunction limits quality of life; however correlation with conventional MRI remains poor...
  21. doi Evaluation of the symbol digit modalities test (SDMT) and MS neuropsychological screening questionnaire (MSNQ) in natalizumab-treated MS patients over 48 weeks
    S A Morrow
    Jacobs Neurological Institute, State University of New York at Buffalo, Buffalo, NY, USA
    Mult Scler 16:1385-92. 2010
    ..Brief cognitive tests to monitor cognitive impairment in patients with multiple sclerosis (MS) are needed...
  22. ncbi Screening for multiple sclerosis cognitive impairment using a self-administered 15-item questionnaire
    R H B Benedict
    Department of Neurology, State University of New York SUNY at Buffalo School of Medicine, Buffalo, New York, USA
    Mult Scler 9:95-101. 2003
    ..83 and a specificity of 0.97. It is concluded, therefore, that this self-administered neuropsychological screening test is reliable and predicts neuropsychological impairment in MS patients with a reasonable degree of accuracy...
  23. ncbi Whole-brain atrophy in multiple sclerosis measured by two segmentation processes from various MRI sequences
    M A Horsfield
    Division of Medical Physics, University of Leicester, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
    J Neurol Sci 216:169-77. 2003
    ..Automated measurement has high reproducibility especially when 2D sequences are used. Semi-automated measurement may have increased accuracy, but with a decreased efficiency and reliability...