Xavier Belles

Summary

Publications

  1. pmc Conserved repressive function of Krüppel homolog 1 on insect metamorphosis in hemimetabolous and holometabolous species
    Jesus Lozano
    Institut de Biologia Evolutiva CSIC UPF, Passeig Martim de la Barceloneta 37, 08003 Barcelona, Spain
    Sci Rep 1:163. 2011
  2. pmc Molecular adaptation and resilience of the insect's nuclear receptor USP
    Arnaud Chaumot
    IRSTEA, UR MALY, Lyon F 69336, France
    BMC Evol Biol 12:199. 2012
  3. doi request reprint Beyond Drosophila: RNAi in vivo and functional genomics in insects
    Xavier Belles
    Institut de Biologia Evolutiva CSIC UPF, Barcelona, Spain
    Annu Rev Entomol 55:111-28. 2010
  4. doi request reprint The hormonal pathway controlling cell death during metamorphosis in a hemimetabolous insect
    Daniel Mané-Padrós
    Institute of Evolutionary Biology CSIC UPF, Passeig Marítim de la Barceloneta 37 49, 08003 Barcelona, Spain
    Dev Biol 346:150-60. 2010
  5. ncbi request reprint Target of rapamycin (TOR) mediates the transduction of nutritional signals into juvenile hormone production
    José L Maestro
    Institut de Biologia Evolutiva CSIC UPF, Passeig Marítim de la Barceloneta 37 49, 08003 Barcelona, Spain
    J Biol Chem 284:5506-13. 2009
  6. ncbi request reprint Systemic RNAi of the cockroach vitellogenin receptor results in a phenotype similar to that of the Drosophila yolkless mutant
    Laura Ciudad
    Department of Physiology and Molecular Biodiversity Institute of Molecular Biology of Barcelona, Barcelona, Spain
    FEBS J 273:325-35. 2006
  7. doi request reprint Conservation of fruitless' role as master regulator of male courtship behaviour from cockroaches to flies
    Elke Clynen
    Institute of Evolutionary Biology CSIC UPF, Passeig Maritim de la Barceloneta 37, 08003, Barcelona, Spain
    Dev Genes Evol 221:43-8. 2011
  8. doi request reprint Key roles of the Broad-Complex gene in insect embryogenesis
    Maria Dolors Piulachs
    Institut de Biologia Evolutiva CSIC UPF, Passeig Marítim 39, 08003 Barcelona, Spain
    Insect Biochem Mol Biol 40:468-75. 2010
  9. ncbi request reprint Effects of hypocholesterolaemic agents on the expression and activity of 3-hydroxy-3-methylglutaryl-CoA reductase in the fat body of the German cockroach
    Rafael Zapata
    Department of Physiology and Molecular Biodiversity, Institut de Biologia Molecular de Barcelona, Barcelona, Spain
    Arch Insect Biochem Physiol 49:177-86. 2002
  10. doi request reprint Nuclear receptor HR4 plays an essential role in the ecdysteroid-triggered gene cascade in the development of the hemimetabolous insect Blattella germanica
    Daniel Mané-Padrós
    Institute of Evolutionary Biology CSIC UPF, Passeig Marítim de la Barceloneta 37 49, 08003 Barcelona, Spain
    Mol Cell Endocrinol 348:322-30. 2012

Collaborators

Detail Information

Publications24

  1. pmc Conserved repressive function of Krüppel homolog 1 on insect metamorphosis in hemimetabolous and holometabolous species
    Jesus Lozano
    Institut de Biologia Evolutiva CSIC UPF, Passeig Martim de la Barceloneta 37, 08003 Barcelona, Spain
    Sci Rep 1:163. 2011
    ..germanica, thereby suggesting that this role is an ancestral condition that has been conserved in insect evolution from hemimetabolous to holometabolous species...
  2. pmc Molecular adaptation and resilience of the insect's nuclear receptor USP
    Arnaud Chaumot
    IRSTEA, UR MALY, Lyon F 69336, France
    BMC Evol Biol 12:199. 2012
    ..This receptor is therefore a good model to study the evolution of plasticity. We tested the hypothesis that selection has shaped the Ligand-Binding Domain (LBD) of USP during evolution of Mecopterida...
  3. doi request reprint Beyond Drosophila: RNAi in vivo and functional genomics in insects
    Xavier Belles
    Institut de Biologia Evolutiva CSIC UPF, Barcelona, Spain
    Annu Rev Entomol 55:111-28. 2010
    ..RNAi also has drawbacks and obscure points, however, such as those related to differences in species sensitivity. Disentangling these differences is one of the main challenges in the RNAi field...
  4. doi request reprint The hormonal pathway controlling cell death during metamorphosis in a hemimetabolous insect
    Daniel Mané-Padrós
    Institute of Evolutionary Biology CSIC UPF, Passeig Marítim de la Barceloneta 37 49, 08003 Barcelona, Spain
    Dev Biol 346:150-60. 2010
    ....
  5. ncbi request reprint Target of rapamycin (TOR) mediates the transduction of nutritional signals into juvenile hormone production
    José L Maestro
    Institut de Biologia Evolutiva CSIC UPF, Passeig Marítim de la Barceloneta 37 49, 08003 Barcelona, Spain
    J Biol Chem 284:5506-13. 2009
    ....
  6. ncbi request reprint Systemic RNAi of the cockroach vitellogenin receptor results in a phenotype similar to that of the Drosophila yolkless mutant
    Laura Ciudad
    Department of Physiology and Molecular Biodiversity Institute of Molecular Biology of Barcelona, Barcelona, Spain
    FEBS J 273:325-35. 2006
    ..The results additionally open the perspective that development genes can be functionally analyzed via systemic RNAi in this basal species...
  7. doi request reprint Conservation of fruitless' role as master regulator of male courtship behaviour from cockroaches to flies
    Elke Clynen
    Institute of Evolutionary Biology CSIC UPF, Passeig Maritim de la Barceloneta 37, 08003, Barcelona, Spain
    Dev Genes Evol 221:43-8. 2011
    ..This suggests that the role of fruitless as master regulator of male sexual behaviour has been conserved along insect evolution, at least from cockroaches to flies...
  8. doi request reprint Key roles of the Broad-Complex gene in insect embryogenesis
    Maria Dolors Piulachs
    Institut de Biologia Evolutiva CSIC UPF, Passeig Marítim 39, 08003 Barcelona, Spain
    Insect Biochem Mol Biol 40:468-75. 2010
    ....
  9. ncbi request reprint Effects of hypocholesterolaemic agents on the expression and activity of 3-hydroxy-3-methylglutaryl-CoA reductase in the fat body of the German cockroach
    Rafael Zapata
    Department of Physiology and Molecular Biodiversity, Institut de Biologia Molecular de Barcelona, Barcelona, Spain
    Arch Insect Biochem Physiol 49:177-86. 2002
    ..Short-term assays showed that both compounds reduce the protein levels and enzymatic activity of HMG-CoA reductase, and long-term experiments revealed that fluvastatin impairs embryo development...
  10. doi request reprint Nuclear receptor HR4 plays an essential role in the ecdysteroid-triggered gene cascade in the development of the hemimetabolous insect Blattella germanica
    Daniel Mané-Padrós
    Institute of Evolutionary Biology CSIC UPF, Passeig Marítim de la Barceloneta 37 49, 08003 Barcelona, Spain
    Mol Cell Endocrinol 348:322-30. 2012
    ..Finally, we have also shown that BgHR4 is an essential gene required for successfully completing nymphal-nymphal and nymphal-adult transitions, by allowing the appropriate delay in the induction of BgFTZ-F1...
  11. doi request reprint Identification and functional characterization of an ovarian aquaporin from the cockroach Blattella germanica L. (Dictyoptera, Blattellidae)
    Alba Herraiz
    Institut de Biologia Evolutiva CSIC UPF and LINC Global, Passeig Maryítim de la Barceloneta 37 49, 08003 Barcelona, Spain
    J Exp Biol 214:3630-8. 2011
    ..The absence of an apparent ovarian phenotype after BgAQP RNAi suggests that other functionally redundant AQPs that were not silenced in our experiments might exist in the ovary of B. germanica...
  12. pmc Brownie, a gene involved in building complex respiratory devices in insect eggshells
    Paula Irles
    Institut de Biologia Evolutiva UPF CSIC, Barcelona, Spain
    PLoS ONE 4:e8353. 2009
    ..The sponge-like body has been well described morphologically, but nothing is known about how it is built up...
  13. ncbi request reprint Subtle roles of microRNAs let-7, miR-100 and miR-125 on wing morphogenesis in hemimetabolan metamorphosis
    Mercedes Rubio
    Institute of Evolutionary Biology CSIC UPF, Passeig Maritim de la Barceloneta 37, 08003, Barcelona, Spain
    J Insect Physiol 59:1089-94. 2013
    ....
  14. doi request reprint Juvenile hormone and allatostatins in the German cockroach embryo
    José L Maestro
    Institut de Biologia Evolutiva CSIC UPF, Passeig Marítim de la Barceloneta 37 49, 08003 Barcelona, Spain
    Insect Biochem Mol Biol 40:660-5. 2010
    ..Moreover, the uncorrelated patterns of JH concentration and CYP15A1 mRNA levels suggest that CYP15A1 expression does not modulate JH production...
  15. doi request reprint Super-induction of Dicer-2 expression by alien double-stranded RNAs: an evolutionary ancient response to viral infection?
    Jesus Lozano
    Institute of Evolutionary Biology, Barcelona, Spain
    Dev Genes Evol 222:229-35. 2012
    ..germanica, a phylogenetically basal insect, suggests that sensing alien RNAs might be an ancestral function of Dicer-2 proteins...
  16. pmc Identifying genes related to choriogenesis in insect panoistic ovaries by Suppression Subtractive Hybridization
    Paula Irles
    Institut de Biologia Evolutiva UPF CSIC, Passeig Maritim de la Barceloneta, Barcelona, Spain
    BMC Genomics 10:206. 2009
    ..To this end, we planned the construction of a Suppression Subtractive Hybridization (SSH) library to identify genes involved in panoistic choriogenesis, using the cockroach Blattella germanica as model...
  17. doi request reprint Broad-complex functions in postembryonic development of the cockroach Blattella germanica shed new light on the evolution of insect metamorphosis
    Jia Hsin Huang
    CSIC Universitat Pompeu Fabra, Passeig Maritim de la Barceloneta, Barcelona, Spain
    Biochim Biophys Acta 1830:2178-87. 2013
    ..In holometabolous species, like Drosophila melanogaster, BR-C expression is inhibited by JH in young larvae and enhanced in mature larvae, when JH declines and BR-C expression specifies the pupal stage...
  18. pmc MicroRNAs in metamorphic and non-metamorphic transitions in hemimetabolan insect metamorphosis
    Mercedes Rubio
    Institute of Evolutionary Biology, CSIC UPF, Passeig Marítim 39, 08003 Barcelona, Spain
    BMC Genomics 13:386. 2012
    ..To gain insight about which miRNAs might be important, we have constructed two miRNA libraries, one of the penultimate, pre-metamorphic nymphal instar (N5) and the other of the last, metamorphic nymphal instar (N6)...
  19. doi request reprint Leucomyosuppressin modulates cardiac rhythm in the cockroach Blattella germanica
    José L Maestro
    Institut de Biologia Evolutiva CSIC UPF, Passeig Maritim de la Barceloneta 37, 08003 Barcelona, Spain
    J Insect Physiol 57:1677-81. 2011
    ..These data suggest that LMS contributes to the modulation of cardiac rhythm in B. germanica during the reproductive cycle...
  20. doi request reprint Nuclear receptor BgFTZ-F1 regulates molting and the timing of ecdysteroid production during nymphal development in the hemimetabolous insect Blattella germanica
    Josefa Cruz
    Institut de Biologia Evolutiva CSIC UPF, Passeig Marítim de la Barceloneta 37 49, Barcelona, Spain
    Dev Dyn 237:3179-91. 2008
    ..Nymphs with silenced BgFTZ-F1 cannot ecdyse, arrest development, and show structures of ectodermal origin duplicated. BgFTZ-F1 also controls the timing of the ecdysteroid molting pulse...
  21. pmc MicroRNA-dependent metamorphosis in hemimetabolan insects
    Eva Gómez-Orte
    Institut de Biologia Evolutiva Consejo Superior de Investigaciones Científicas and Universitat Pompeu Fabra, Passeig Maritim de la Barceloneta, 37 49, 08003 Barcelona, Spain
    Proc Natl Acad Sci U S A 106:21678-82. 2009
    ..The experiments show that miRNAs play a key role in hemimetabolan metamorphosis, perhaps regulating genes that are juvenile hormone targets...
  22. doi request reprint Identification of a tachykinin-related peptide with orexigenic properties in the German cockroach
    Nuria Pascual
    Department of Physiology and Molecular Biodiversity, Institut de Biologia Molecular de Barcelona CSIC, Jordi Girona 18 26, Barcelona, Spain
    Peptides 29:386-92. 2008
    ....
  23. pmc Structural and RNAi characterization of the German cockroach lipophorin receptor, and the evolutionary relationships of lipoprotein receptors
    Laura Ciudad
    Department of Physiology and Molecular Biodiversity, Institut de Biologia Molecular de Barcelona, CSIC, Jordi Girona 18, Barcelona, Spain
    BMC Mol Biol 8:53. 2007
    ..The aim of the present work was to characterize the LpR of the cockroach Blattella germanica, not only molecularly but also functionally using RNAi techniques, and to place LpRs in a phylogenetical context among lipoprotein receptors...
  24. ncbi request reprint Silencing allatostatin expression using double-stranded RNA targeted to preproallatostatin mRNA in the German cockroach
    José L Maestro
    Department of Physiology and Molecular Biodiversity, Institut de Biologia Molecular de Barcelona, CSIC, Barcelona, Spain
    Arch Insect Biochem Physiol 62:73-9. 2006
    ..Nevertheless, while brain AST levels were reduced approximately 70-80%, JH synthesis did not increase in any of the age groups tested...