Peter Wostyn

Summary

Country: Belgium

Publications

  1. doi request reprint Senescent changes in cerebrospinal fluid circulatory physiology and their role in the pathogenesis of normal-tension glaucoma
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Beernem, Belgium
    Am J Ophthalmol 156:5-14.e2. 2013
  2. doi request reprint Genes involved in cerebrospinal fluid production as candidate genes for late-onset Alzheimer's disease: a hypothesis
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Beernem, Belgium
    J Neurogenet 25:195-200. 2011
  3. doi request reprint Are intracranial pressure fluctuations important in glaucoma?
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Med Hypotheses 77:598-600. 2011
  4. doi request reprint Alzheimer's disease: cerebral glaucoma?
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Med Hypotheses 74:973-7. 2010
  5. pmc More advanced Alzheimer's disease may be associated with a decrease in cerebrospinal fluid pressure
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Cerebrospinal Fluid Res 6:14. 2009
  6. doi request reprint Alzheimer's disease and glaucoma: is there a causal relationship?
    P Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Br J Ophthalmol 93:1557-9. 2009
  7. ncbi request reprint The Valsalva maneuver and Alzheimer's disease: is there a link?
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Curr Alzheimer Res 6:59-68. 2009
  8. ncbi request reprint Alzheimer's disease-related changes in diseases characterized by elevation of intracranial or intraocular pressure
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Clin Neurol Neurosurg 110:101-9. 2008
  9. ncbi request reprint Can chronic increased intracranial pressure or exposure to repetitive intermittent intracranial pressure elevations raise your risk for Alzheimer's disease?
    P Wostyn
    PC Sint Amandus, Beernem, Belgium
    Med Hypotheses 62:925-30. 2004
  10. pmc Increased Cerebrospinal Fluid Production as a Possible Mechanism Underlying Caffeine's Protective Effect against Alzheimer's Disease
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Int J Alzheimers Dis 2011:617420. 2011

Detail Information

Publications13

  1. doi request reprint Senescent changes in cerebrospinal fluid circulatory physiology and their role in the pathogenesis of normal-tension glaucoma
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Beernem, Belgium
    Am J Ophthalmol 156:5-14.e2. 2013
    ..To evaluate the evidence supporting a role for senescent changes in cerebrospinal fluid (CSF) circulatory physiology in the pathogenesis of normal-tension glaucoma (NTG)...
  2. doi request reprint Genes involved in cerebrospinal fluid production as candidate genes for late-onset Alzheimer's disease: a hypothesis
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Beernem, Belgium
    J Neurogenet 25:195-200. 2011
    ..In this paper, the authors hypothesize that genes and variations of genes involved in the CSF production and absorption may contribute to the pathogenesis of late-onset AD...
  3. doi request reprint Are intracranial pressure fluctuations important in glaucoma?
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Med Hypotheses 77:598-600. 2011
    ..The effect of ICP fluctuation might be comparable to that of IOP fluctuation, which has been recognized as an independent risk factor for glaucoma progression...
  4. doi request reprint Alzheimer's disease: cerebral glaucoma?
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Med Hypotheses 74:973-7. 2010
    ..Further studies are warranted, however, especially to determine the possible role of high ICP in at least some cases of AD...
  5. pmc More advanced Alzheimer's disease may be associated with a decrease in cerebrospinal fluid pressure
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Cerebrospinal Fluid Res 6:14. 2009
    ..This could result in an abnormally high trans-lamina cribrosa pressure difference and lead to glaucomatous damage...
  6. doi request reprint Alzheimer's disease and glaucoma: is there a causal relationship?
    P Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Br J Ophthalmol 93:1557-9. 2009
    ..Therefore, we hypothesise that an abnormal high trans-lamina cribrosa pressure difference may explain why patients with AD have a greater risk for developing glaucoma...
  7. ncbi request reprint The Valsalva maneuver and Alzheimer's disease: is there a link?
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Curr Alzheimer Res 6:59-68. 2009
    ..If confirmed, this hypothesis could have implications in clinical practice...
  8. ncbi request reprint Alzheimer's disease-related changes in diseases characterized by elevation of intracranial or intraocular pressure
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Clin Neurol Neurosurg 110:101-9. 2008
    ..Further studies are warranted, however, especially to elucidate the role of elevated mechanical forces in Alzheimer's disease neuropathogenesis...
  9. ncbi request reprint Can chronic increased intracranial pressure or exposure to repetitive intermittent intracranial pressure elevations raise your risk for Alzheimer's disease?
    P Wostyn
    PC Sint Amandus, Beernem, Belgium
    Med Hypotheses 62:925-30. 2004
    ..To test the validity of the hypothesis that exposure to repetitive but nonsustained ICP elevations may predispose to AD a non-invasive, epidemiological study is proposed in this paper...
  10. pmc Increased Cerebrospinal Fluid Production as a Possible Mechanism Underlying Caffeine's Protective Effect against Alzheimer's Disease
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Int J Alzheimers Dis 2011:617420. 2011
    ..Further, we propose a preclinical experimental design allowing evaluation of this hypothesis...
  11. pmc Choroidal Proteins Involved in Cerebrospinal Fluid Production may be Potential Drug Targets for Alzheimer's Disease Therapy
    Peter Wostyn
    Department of Psychiatry, PC Sint Amandus, Reigerlostraat 10, 8730 Beernem, Belgium
    Perspect Medicin Chem 5:11-7. 2011
    ..Other potential mechanisms of cognitive protection by caffeine have been suggested by recent studies...
  12. ncbi request reprint An abnormal high trans-lamina cribrosa pressure difference: a missing link between Alzheimer's disease and glaucoma?
    Peter Wostyn
    Clin Neurol Neurosurg 110:753-4. 2008
  13. ncbi request reprint Is extensive use of the Valsalva maneuver associated with an increased risk for Alzheimer's disease?
    Peter Wostyn
    Med Hypotheses 66:445-6. 2006