Benoit Stijlemans

Summary

Affiliation: Vrije Universiteit Brussel
Country: Belgium

Publications

  1. Stijlemans B, Vankrunkelsven A, Brys L, Magez S, De Baetselier P. Role of iron homeostasis in trypanosomiasis-associated anemia. Immunobiology. 2008;213:823-35 pubmed publisher
    ....
  2. Stijlemans B, Guilliams M, Raes G, Beschin A, Magez S, De Baetselier P. African trypanosomosis: from immune escape and immunopathology to immune intervention. Vet Parasitol. 2007;148:3-13 pubmed
    ..Finally, the possibility to interfere with such activation states hereby providing new therapeutical modalities in the treatment of this infectious disease will be illustrated. ..
  3. Stijlemans B, Vankrunkelsven A, Caljon G, Bockstal V, Guilliams M, Bosschaerts T, et al. The central role of macrophages in trypanosomiasis-associated anemia: rationale for therapeutical approaches. Endocr Metab Immune Disord Drug Targets. 2010;10:71-82 pubmed
    ....
  4. Stijlemans B, Caljon G, Natesan S, Saerens D, Conrath K, Perez Morga D, et al. High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis. PLoS Pathog. 2011;7:e1002072 pubmed publisher
    ....
  5. Sparkes A, De Baetselier P, Roelants K, De Trez C, Magez S, Van Ginderachter J, et al. The non-mammalian MIF superfamily. Immunobiology. 2017;222:473-482 pubmed publisher
    ..Consequently, a combined targeting of both parasitic and host MIF could lead to more effective treatment strategies for parasitic diseases of socioeconomic importance. ..
  6. Stijlemans B, Baral T, Guilliams M, Brys L, Korf J, Drennan M, et al. A glycosylphosphatidylinositol-based treatment alleviates trypanosomiasis-associated immunopathology. J Immunol. 2007;179:4003-14 pubmed
    ....
  7. Stijlemans B, Vankrunkelsven A, Brys L, Raes G, Magez S, De Baetselier P. Scrutinizing the mechanisms underlying the induction of anemia of inflammation through GPI-mediated modulation of macrophage activation in a model of African trypanosomiasis. Microbes Infect. 2010;12:389-99 pubmed publisher
    ..Collectively, our results demonstrate that reprogramming macrophages towards an anti-inflammatory state alleviates anemia of inflammation by normalizing iron homeostasis and restoring erythropoiesis...

Locale

Detail Information

Publications7

  1. Stijlemans B, Vankrunkelsven A, Brys L, Magez S, De Baetselier P. Role of iron homeostasis in trypanosomiasis-associated anemia. Immunobiology. 2008;213:823-35 pubmed publisher
    ....
  2. Stijlemans B, Guilliams M, Raes G, Beschin A, Magez S, De Baetselier P. African trypanosomosis: from immune escape and immunopathology to immune intervention. Vet Parasitol. 2007;148:3-13 pubmed
    ..Finally, the possibility to interfere with such activation states hereby providing new therapeutical modalities in the treatment of this infectious disease will be illustrated. ..
  3. Stijlemans B, Vankrunkelsven A, Caljon G, Bockstal V, Guilliams M, Bosschaerts T, et al. The central role of macrophages in trypanosomiasis-associated anemia: rationale for therapeutical approaches. Endocr Metab Immune Disord Drug Targets. 2010;10:71-82 pubmed
    ....
  4. Stijlemans B, Caljon G, Natesan S, Saerens D, Conrath K, Perez Morga D, et al. High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis. PLoS Pathog. 2011;7:e1002072 pubmed publisher
    ....
  5. Sparkes A, De Baetselier P, Roelants K, De Trez C, Magez S, Van Ginderachter J, et al. The non-mammalian MIF superfamily. Immunobiology. 2017;222:473-482 pubmed publisher
    ..Consequently, a combined targeting of both parasitic and host MIF could lead to more effective treatment strategies for parasitic diseases of socioeconomic importance. ..
  6. Stijlemans B, Baral T, Guilliams M, Brys L, Korf J, Drennan M, et al. A glycosylphosphatidylinositol-based treatment alleviates trypanosomiasis-associated immunopathology. J Immunol. 2007;179:4003-14 pubmed
    ....
  7. Stijlemans B, Vankrunkelsven A, Brys L, Raes G, Magez S, De Baetselier P. Scrutinizing the mechanisms underlying the induction of anemia of inflammation through GPI-mediated modulation of macrophage activation in a model of African trypanosomiasis. Microbes Infect. 2010;12:389-99 pubmed publisher
    ..Collectively, our results demonstrate that reprogramming macrophages towards an anti-inflammatory state alleviates anemia of inflammation by normalizing iron homeostasis and restoring erythropoiesis...