Research Topics
Genomes and Genes | Marianne L VozSummaryCountry: Belgium Publications
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Publications
Fast homozygosity mapping and identification of a zebrafish ENU-induced mutation by whole-genome sequencingMarianne L Voz
Laboratoire de Biologie Moléculaire et de Génie Génétique, Universite de Liege, Sart Tilman, Belgium
PLoS ONE 7:e34671. 2012..In conclusion, this study constitutes a proof-of-concept that whole-genome sequencing is a fast and effective alternative to the classical positional cloning strategies in zebrafish...
Expression of zebrafish pax6b in pancreas is regulated by two enhancers containing highly conserved cis-elements bound by PDX1, PBX and PREP factorsFrançois M Delporte
Unit of Molecular Biology and Genetic Engineering, University of Liege, GIGA R, B34, Avenue de l Hopital, 1, B 4000 Liege, Belgium
BMC Dev Biol 8:53. 2008....
Microarray screening for target genes of the proto-oncogene PLAG1Marianne L Voz
Laboratory for Molecular Oncology, Center for Human Genetics, KU Leuven and Flanders Interuniversity Institute for Biotechnology, Herestraat 49, Leuven B 3000, Belgium
Oncogene 23:179-91. 2004..Concordance between these two sets of experiments pinpointed 12 genes that were significantly and consistently upregulated in pleomorphic adenomas and in PLAG1-expressing cells, identifying them as putative PLAG1 targets in these tumors...
Zebrafish Sox7 and Sox18 function together to control arterial-venous identityHelene Pendeville
GIGA Research Unité de Biologie Moleculaire et Génie Génétique, Tour B34, Universite de Liege, B 4000 Sart Tilman, Belgium
Dev Biol 317:405-16. 2008..The striking similarities between the phenotype of Sox7/Sox18 morphants and Gridlock mutants strongly suggest that Sox7 and Sox18 control arterial-venous identity by regulating Gridlock expression...
Reciprocal endoderm-mesoderm interactions mediated by fgf24 and fgf10 govern pancreas developmentIsabelle Manfroid
GIGA Research Unité de Biologie Moleculaire et Génie Génétique, Tour B34, Universite de Liege, B 4000 Sart Tilman, Belgium
Development 134:4011-21. 2007....
The tumorigenic diversity of the three PLAG family members is associated with different DNA binding capacitiesKaren Hensen
Laboratory for Molecular Oncology, Center for Human Genetics, University of Leuven KUL and Flanders Interuniversity Institute for Biotechnology VIB, Herestraat 49 B 3000 Leuven, Belgium
Cancer Res 62:1510-7. 2002..This strongly suggests that the oncogenic capacity of PLAG1 and PLAGL2 is mediated at least partly by activating the insulin-like growth factor-II mitogenic pathway...
Identification of a karyopherin alpha 2 recognition site in PLAG1, which functions as a nuclear localization signalCaroline V Braem
Laboratory for Molecular Oncology, Department of Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology, Herestraat 49, B 3000 Leuven, Belgium
J Biol Chem 277:19673-8. 2002..These observations indicate that the nuclear import of PLAG1 is governed by its zinc finger domain and by NLS1, a karyopherin alpha2 recognition site...
Sesn1 is a novel gene for left-right asymmetry and mediating nodal signalingHilde Peeters
Department of Human Genetics, Clinical Genetics Unit, University of Leuven, Belgium
Hum Mol Genet 15:3369-77. 2006..In this study, we identify SESN1 as an indispensable gene for vertebrate left-right asymmetry and a new player in mediating Nodal signaling...
The Na+/PO4 cotransporter SLC20A1 gene labels distinct restricted subdomains of the developing pronephros in Xenopus and zebrafish embryosMassimo Nichane
Laboratoire d Embryologie Moleculaire, Universite Libre de Bruxelles, Institut de Biologie et de Médecine Moléculaires IBMM, Gosselies, Belgium
Gene Expr Patterns 6:667-72. 2006..Together, our data reveal that the zebrafish and Xenopus pronephros have non-identical proximo-distal organizations...
Cloning and embryonic expression of zebrafish PLAG genesHelene Pendeville
Laboratoire de Biologie Moléculaire et Génie Génétique, Center for Biomedical Integrated Genoproteomics, University of Liege, B6 4000 Liège Sart Tilman, Belgium
Gene Expr Patterns 6:267-76. 2006..This hypothesis was proven for the ventricular zone shown to be a highly proliferative zone using the anti-phosphohistone H3 antibody that detects cells in mitosis...
Evi1 is specifically expressed in the distal tubule and duct of the Xenopus pronephros and plays a role in its formationClaude Van Campenhout
Laboratoire d Embryologie Moleculaire, Universite Libre de Bruxelles, Institut de Biologie et de Médecine Moléculaires IBMM, Rue des Profs Jeener et Brachet 12, B 6041 Gosselies, Belgium
Dev Biol 294:203-19. 2006..Together, these data indicate that Evi1 plays a role in the proximo-distal patterning of the pronephros and suggest that it may do so by functioning as a CtBP dependent repressor...
