Steven Van Laere

Summary

Country: Belgium

Publications

  1. pmc Array-based DNA methylation profiling for breast cancer subtype discrimination
    Ilse Van der Auwera
    Translational Cancer Research Group, Laboratory of Pathology, University of Antwerp University Hospital Antwerp, Oncology Center, Sint Augustinus, Antwerp, Belgium
    PLoS ONE 5:e12616. 2010
  2. pmc Integrated miRNA and mRNA expression profiling of the inflammatory breast cancer subtype
    I Van der Auwera
    Translational Cancer Research Group Laboratory of Pathology, University of Antwerp University Hospital Antwerp, Oncology Centre, Sint Augustinus, Oosterveldlaan 24, B 2610 Antwerp, Belgium
    Br J Cancer 103:532-41. 2010
  3. ncbi request reprint Uncovering the molecular secrets of inflammatory breast cancer biology: an integrated analysis of three distinct affymetrix gene expression datasets
    Steven J Van Laere
    Translational Cancer Research Unit, Oncology Center, General Hospital Sint Augustinus, Antwerp, Wilrijk, Belgium
    Clin Cancer Res 19:4685-96. 2013
  4. pmc Expression profiling of cancerous and normal breast tissues identifies microRNAs that are differentially expressed in serum from patients with (metastatic) breast cancer and healthy volunteers
    Eleni van Schooneveld
    Department of Oncology, University Hospitals Leuven and Catholic University Leuven, Herestraat 49, Leuven, B3000 Belgium
    Breast Cancer Res 14:R34. 2012
  5. pmc Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patients
    Ilse Van der Auwera
    Translational Cancer Research Group Laboratory of Pathology, University of Antwerp University Hospital Antwerp Oncology Centre, General Hospital St Augustinus, 2610 Antwerp, Belgium
    BMC Cancer 10:97. 2010
  6. doi request reprint Is there a role for mammary stem cells in inflammatory breast carcinoma?: a review of evidence from cell line, animal model, and human tissue sample experiments
    Steven Van Laere
    Translational Cancer Research Group, Laboratory of Pathology, University of Antwerp University Hospital Antwerp, Edegem, Belgium
    Cancer 116:2794-805. 2010
  7. ncbi request reprint Distinct molecular signature of inflammatory breast cancer by cDNA microarray analysis
    Steven Van Laere
    Translational Cancer Research Group, Lab Pathology, University of Antwerp University Hospital Antwerp, Edegem and General Hospital, Sint Augustinus, Wilrijk, Belgium
    Breast Cancer Res Treat 93:237-46. 2005
  8. doi request reprint Relapse-free survival in breast cancer patients is associated with a gene expression signature characteristic for inflammatory breast cancer
    Steven Van Laere
    Translational Cancer Research Group, Laboratory of Pathology, University of Antwerp and Oncology Center, General Hospital Sint Augustinus, Wilrijk, Belgium
    Clin Cancer Res 14:7452-60. 2008
  9. doi request reprint Hallmarks of aromatase inhibitor drug resistance revealed by epigenetic profiling in breast cancer
    Maurice P H M Jansen
    Authors Affiliations Department of Medical Oncology, Erasmus University Medical Center, Cancer Institute, Rotterdam Departments of Molecular Carcinogenesis and Molecular Pathology, Central Genomic Facility, the Netherlands Cancer Institute Agendia NV, Amsterdam, the Netherlands and Translational Cancer Research Unit, Laboratory of Pathology, Antwerp University Oncology Centre, GZA Hospitals St Augustinus, Antwerp, Belgium
    Cancer Res 73:6632-41. 2013
  10. doi request reprint The histological growth pattern of colorectal cancer liver metastases has prognostic value
    Gert G Van den Eynden
    Translational Cancer Research Unit, Augustinus Hospital, Oosterveldlaan 24, 2610, Wilrijk, Antwerp, Belgium
    Clin Exp Metastasis 29:541-9. 2012

Detail Information

Publications10

  1. pmc Array-based DNA methylation profiling for breast cancer subtype discrimination
    Ilse Van der Auwera
    Translational Cancer Research Group, Laboratory of Pathology, University of Antwerp University Hospital Antwerp, Oncology Center, Sint Augustinus, Antwerp, Belgium
    PLoS ONE 5:e12616. 2010
    ..We sought to determine whether the distinction of the inflammatory breast cancer (IBC) phenotype from the non-IBC phenotype by transcriptomics could be sustained by methylomics...
  2. pmc Integrated miRNA and mRNA expression profiling of the inflammatory breast cancer subtype
    I Van der Auwera
    Translational Cancer Research Group Laboratory of Pathology, University of Antwerp University Hospital Antwerp, Oncology Centre, Sint Augustinus, Oosterveldlaan 24, B 2610 Antwerp, Belgium
    Br J Cancer 103:532-41. 2010
    ..MicroRNAs (miRNAs) are key regulators of gene expression. In this study, we explored whether altered miRNA expression has a prominent role in defining the inflammatory breast cancer (IBC) phenotype...
  3. ncbi request reprint Uncovering the molecular secrets of inflammatory breast cancer biology: an integrated analysis of three distinct affymetrix gene expression datasets
    Steven J Van Laere
    Translational Cancer Research Unit, Oncology Center, General Hospital Sint Augustinus, Antwerp, Wilrijk, Belgium
    Clin Cancer Res 19:4685-96. 2013
    ..Here, we present the integration of three Affymetrix expression datasets collected through the World IBC Consortium allowing us to interrogate the molecular profile of IBC using the largest series of IBC samples ever reported...
  4. pmc Expression profiling of cancerous and normal breast tissues identifies microRNAs that are differentially expressed in serum from patients with (metastatic) breast cancer and healthy volunteers
    Eleni van Schooneveld
    Department of Oncology, University Hospitals Leuven and Catholic University Leuven, Herestraat 49, Leuven, B3000 Belgium
    Breast Cancer Res 14:R34. 2012
    ..In the current study, we evaluated the feasibility and clinical utility of circulating miRNAs as biomarkers for the detection and staging of breast cancer...
  5. pmc Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patients
    Ilse Van der Auwera
    Translational Cancer Research Group Laboratory of Pathology, University of Antwerp University Hospital Antwerp Oncology Centre, General Hospital St Augustinus, 2610 Antwerp, Belgium
    BMC Cancer 10:97. 2010
    ....
  6. doi request reprint Is there a role for mammary stem cells in inflammatory breast carcinoma?: a review of evidence from cell line, animal model, and human tissue sample experiments
    Steven Van Laere
    Translational Cancer Research Group, Laboratory of Pathology, University of Antwerp University Hospital Antwerp, Edegem, Belgium
    Cancer 116:2794-805. 2010
    ..Recently, the latter mechanism was identified as a prerequisite for the induction of stem cell characteristics in breast cancer cells...
  7. ncbi request reprint Distinct molecular signature of inflammatory breast cancer by cDNA microarray analysis
    Steven Van Laere
    Translational Cancer Research Group, Lab Pathology, University of Antwerp University Hospital Antwerp, Edegem and General Hospital, Sint Augustinus, Wilrijk, Belgium
    Breast Cancer Res Treat 93:237-46. 2005
    ..The results of our study provide potential targets for the treatment of patients with IBC...
  8. doi request reprint Relapse-free survival in breast cancer patients is associated with a gene expression signature characteristic for inflammatory breast cancer
    Steven Van Laere
    Translational Cancer Research Group, Laboratory of Pathology, University of Antwerp and Oncology Center, General Hospital Sint Augustinus, Wilrijk, Belgium
    Clin Cancer Res 14:7452-60. 2008
    ....
  9. doi request reprint Hallmarks of aromatase inhibitor drug resistance revealed by epigenetic profiling in breast cancer
    Maurice P H M Jansen
    Authors Affiliations Department of Medical Oncology, Erasmus University Medical Center, Cancer Institute, Rotterdam Departments of Molecular Carcinogenesis and Molecular Pathology, Central Genomic Facility, the Netherlands Cancer Institute Agendia NV, Amsterdam, the Netherlands and Translational Cancer Research Unit, Laboratory of Pathology, Antwerp University Oncology Centre, GZA Hospitals St Augustinus, Antwerp, Belgium
    Cancer Res 73:6632-41. 2013
    ..The classification potential of these genes was only partially preserved in a cohort of 101 patients who received first-line tamoxifen treatment, suggesting some treatment selectivity in patient classification...
  10. doi request reprint The histological growth pattern of colorectal cancer liver metastases has prognostic value
    Gert G Van den Eynden
    Translational Cancer Research Unit, Augustinus Hospital, Oosterveldlaan 24, 2610, Wilrijk, Antwerp, Belgium
    Clin Exp Metastasis 29:541-9. 2012
    ....