Werner Van Steenbergen
Affiliation: University Hospitals Leuven
- Primary sclerosing cholangitis complicated by amyloid A amyloidosis: complete regression of the nephrotic syndrome by liver transplantationWerner Van Steenbergen
Department of Internal Medicine, Liver Unit, University Hospital Gasthuisberg, Catholic University of Leuven, Turnhout, Belgium
Eur J Gastroenterol Hepatol 22:1265-70. 2010..This is the first report describing the occurrence of amyloid A amyloidosis in primary sclerosing cholangitis, and the reversal of a secondary amyloidosis-induced nephrotic syndrome as a result of liver transplantation...
- The first prospective endoscopic experience with the ePTFE-covered Viabil stent in patients with a distal malignant biliary stenosisW Van Steenbergen
University Hospital Gasthuisberg, Department of Liver, Biliary and Pancreatic Diseases, Unit for Biliopancreatic Endoscopy, Catholic University of Leuven, Belgium
Acta Gastroenterol Belg 73:18-24. 2010..Experience with the new ePTFE-covered Viabil stent is mainly limited to the percutaneous approach. We report our experience with its endoscopic application in patients with distal malignant biliary obstructions...
- Cystic fibrosis transmembrane conductance regulator gene polymorphisms in patients with primary sclerosing cholangitisLiesbet Henckaerts
Department of Gastroenterology, University Hospital Gasthuisberg, Catholic University of Leuven, Herestraat 49, B 3000 Leuven, Belgium
J Hepatol 50:150-7. 2009..The histological features in the liver of PSC patients are similar to those observed in cystic fibrosis (CF). Our aim was to study whether variants in the CFTR gene are associated with the occurrence and/or evolution of PSC...
- Endoscopic resection of ampullary lesions: a single-center 8-year retrospective cohort study of 91 patients with long-term follow-upWim Laleman
Department of Liver and Biliopancreatic disorders, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Leuven, Belgium
Surg Endosc 27:3865-76. 2013..Moreover, multiple tangible issues remain. The aim of our study was to evaluate efficacy, safety, and outcome of endoscopic ampullectomy and compare it to existing literature..
- Malignancies and mortality in 200 patients with primary sclerosering cholangitis: a long-term single-centre studyJohan Fevery
Department of Hepatology, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium
Liver Int 32:214-22. 2012..The outcome of primary sclerosing cholangitis (PSC) has improved by liver transplantation (LT), but patients often develop malignancies. We analysed morbidity and mortality patterns to define strategies to prevent complications...
- CC-type chemokine receptor 5-Delta32 mutation protects against primary sclerosing cholangitisLiesbet Henckaerts
Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
Inflamm Bowel Dis 12:272-7. 2006..We therefore investigated the role of the functional 32-bp deletion in this gene (CCR5-Delta32) with regard to susceptibility to PSC...
- Incidence, diagnosis, and therapy of cholangiocarcinoma in patients with primary sclerosing cholangitisJohan Fevery
Division of Hepatobiliary, University Hospital Gasthuisberg, Catholic University of Leuven, B3000 Leuven, Belgium
Dig Dis Sci 52:3123-35. 2007..Pretransplant radiotherapy with 5-FU chemosensitization followed by endoscopic brachytherapy with iridium-192 seems to greatly improve the outcome of transplantation. Treatment with ursodeoxycholic acid may prevent development of CCA...
- Transcatheter arterial embolization for iatrogenic hemobilia is a safe and effective procedure: case series and review of the literatureThomas Marynissen
Department of Liver and Biliopancreatic Diseases bInterventional Radiology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, Leuven, Belgium
Eur J Gastroenterol Hepatol 24:905-9. 2012..Hemobilia is an uncommon cause of gastrointestinal bleeding. The etiology is diverse, but most often, it is iatrogenic. The present study aims to reassess the clinical picture and the treatment of choice...
- Treatment, by insertion of multiple uncovered metallic stents, of intraductal papillary mucinous neoplasm of the pancreas with biliary obstruction by mucus impactionLaura Seynaeve
Unit for Liver, Biliary and Pancreatic Diseases, Department of Internal Medicine, University Hospital Gasthuisberg, Catholic University of Leuven, Leuven, Belgium
Pancreatology 7:540-3. 2007..Repeated insertions of plastic and of single covered metallic stents were unsuccessful due to mucus-induced migration of these stents...
- Congenital veno-venous malformations of the liver: widely variable clinical presentationsPeter Witters
Laboratory of Hepatology, Catholic University of Leuven, Leuven, Belgium
J Gastroenterol Hepatol 23:e390-4. 2008..However, their clinical presentation is less dependent on the anatomical type...
- Primary sclerosing cholangitis in two brothers: report of a family with special emphasis on molecular HLA and MICA genotypingWerner Van Steenbergen
Unit for Liver Diseases, Department of Internal Medicine, University Hospital Gasthuisberg, Belgium
Eur J Gastroenterol Hepatol 17:767-71. 2005..Their unaffected father and sister both carried the protective DR4 allele. The presence of PSC in two brothers, and the distribution of HLA haplotypes and MICA alleles, adds supportive evidence for an immunogenetic origin of PSC...
- Improvement of autoimmune hepatitis during pregnancy followed by flare-up after deliveryElwin Buchel
Divison of Hepatobiliary and Pancreas Diseases, University Hospital Gasthuisberg, Leuven, Belgium
Am J Gastroenterol 97:3160-5. 2002..Pregnancy in autoimmune hepatitis has been a rare event, but it has become more frequent with improved therapy. The present study aimed to analyze the consequences for mother and child in patients with autoimmune hepatitis...
- Systemic treatment of pancreatic cancerEric Van Cutsem
Digestive Oncology Unit, University Hospital Gasthuisberg, 3000 Leuven, Belgium
Eur J Gastroenterol Hepatol 16:265-74. 2004..The systematic evaluation of new drugs in well designed clinical trials and the search for new molecular targets for treatment are crucial in our aim to improve the outcome for patients with pancreatic cancer...