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Genomes and Genes | Paul Van de HeyningSummaryAffiliation: University Hospital Antwerp Country: Belgium Publications
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Publications
Tinnitus: from cochlear to corticalP Van de Heyning
Brain Research Institute, Antwerp Unversity Hospital of Innovative and Interdisciplinairy Neuromodulation, Belgium
B-ENT 3:1-2. 2007..Tinnitus is presented in view of translational research from research to clinical application...
Electric acoustic stimulation: a new era in prosthetic hearing rehabilitationPaul Van de Heyning
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Antwerp, University of Antwerp, Antwerp, Belgium
Adv Otorhinolaryngol 67:1-5. 2010..EAS has led to a new era in prosthetic hearing rehabilitation providing new understanding of basic physiological, psychoacoustic and medical aspects of the inner ear...
Surgical treatment of Meniere's diseasePaul H Van de Heyning
University Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium
Curr Opin Neurol 18:23-8. 2005..This review comprises new insights from and discusses the impact of recent medical publications on the surgical treatment of Meniere's disease...
Tenotomy of the tensor tympani and stapedius tendons in Ménière's diseaseC F J De Valck
Antwerp University Research centre for Equilibrium and Aerospace, Univ Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital
B-ENT 5:1-6. 2009..Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease...
Tinnitus: a multidisciplinary clinical approachP Van de Heyning
University Department of Otorhinolaryngology and Head and Neck Surgery, University Multidisciplinary Tinnitus Centre of Antwerp, Antwerp University Hospital UZA, Faculty of Medicine, University of Antwerp, Belgium
B-ENT 3:3-10. 2007..The psycho-acoustic characteristics and the influence on health-related quality of life is a compulsory complementary assessment to establish a complete picture of the patient...
Theta-gamma dysrhythmia and auditory phantom perceptionDirk De Ridder
BRAI2N, Tinnitus Research Initiative Clinic, and Department of Neurosurgery, University Hospital Antwerp, Belgium
J Neurosurg 114:912-21. 2011..These data suggest that thetagamma coupling as proposed by the thalamocortical dysrhythmia model might be causally related to a conscious auditory phantom percept...
Three-year postimplantation auditory outcomes in children with sequential bilateral cochlear implantationFanny Scherf
Department of Otorhinolaryngology, Antwerp University Hospital, Antwerp University, Edegem, Belgium
Ann Otol Rhinol Laryngol 118:336-44. 2009..We report on the auditory abilities and speech performance in quiet and noise of 35 children with sequential bilateral cochlear implantation after 3 years of bilateral implant use...
Genotype-phenotype correlation for DFNA22: characterization of non-syndromic, autosomal dominant, progressive sensorineural hearing loss due to MYO6 mutationsVedat Topsakal
Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
Audiol Neurootol 15:211-20. 2010..The phenotypes of all hitherto reported DFNA22 families with mutations in the MYO6 gene have been studied and compared. It seems that genetic defects that spare the motor domain of the myosin VI protein have a milder phenotype...
Dorsolateral prefrontal cortex transcranial magnetic stimulation and electrode implant for intractable tinnitusDirk De Ridder
Brai 2 n, University Hospital Antwerp, Antwerp, Belgium
World Neurosurg 77:778-84. 2012..It is characterized by gamma-band activity in the frontal cortex that can be visualized with the use of electroencephalography, magnetoencephalography, and functional magnetic resonance imaging (fMRI)...
Bilateral dorsolateral prefrontal cortex modulation for tinnitus by transcranial direct current stimulation: a preliminary clinical studySven Vanneste
BRAI2N, TRI, Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium
Exp Brain Res 202:779-85. 2010..This was, however, not the case for tinnitus intensity. Our study supports the involvement of the prefrontal cortex in the pathophysiology of tinnitus...
Hospital nurse practice environment, burnout, job outcomes and quality of care: test of a structural equation modelPeter Van Bogaert
Department of Nursing, University Hospital Antwerp, Belgium
J Adv Nurs 65:2175-85. 2009..The aim of the study was to investigate relationships between nurse practice environment, burnout, job outcomes and nurse-assessed quality of care...
Transcranial magnetic stimulation and extradural electrodes implanted on secondary auditory cortex for tinnitus suppressionDirk De Ridder
BRAI2N, University Hospital Antwerp, Belgium
J Neurosurg 114:903-11. 2011....
No evidence for association between the renin-angiotensin-aldosterone system and otosclerosis in a large Belgian-Dutch populationIsabelle Schrauwen
Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
Otol Neurotol 30:1079-83. 2009..In the current study, a replication study was done in a large Belgian-Dutch population to investigate whether this association could be replicated...
Clinical need for a Baha trial in patients with single-sided sensorineural deafness. Analysis of a Baha database of 196 patientsJolien Desmet
Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Antwerp, Wilrijkstraat 10, Edegem, 2650, Antwerp, Belgium
Eur Arch Otorhinolaryngol 269:799-805. 2012..The authors advocate that all patients, suffering from SSD, should be offered the opportunity to try a Baha device as no factors could be found that determine the decision of a patient following the trial period...
A splice-site mutation and overexpression of MYO6 cause a similar phenotype in two families with autosomal dominant hearing lossNele Hilgert
Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
Eur J Hum Genet 16:593-602. 2008..Most likely, the overexpression is caused by a mutation in an unidentified regulatory region of the gene. This study indicates that the inner ear hair cells are sensitive to changes in expression levels of MYO6...
Bilateral electric acoustic stimulation: a comparison of partial and deep cochlear electrode insertion. A longitudinal case studyAndrea Kleine Punte
University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
Adv Otorhinolaryngol 67:144-52. 2010..The aims were to assess whether low-frequency hearing could be preserved after deep electrode insertion, as well as to assess the benefit of bilateral EAS surgery compared to monaural EAS...
Association of bone morphogenetic proteins with otosclerosisIsabelle Schrauwen
Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
J Bone Miner Res 23:507-16. 2008..We found significant association in both populations with BMP2 and BMP4, implicating these two genes in the pathogenesis of this disease...
Burst stimulation of the auditory cortex: a new form of neurostimulation for noise-like tinnitus suppressionDirk De Ridder
BRAI2N, University Hospital Antwerp, Edegem, Belgium
J Neurosurg 112:1289-94. 2010..Burst firing is shown to be more powerful in activating the cerebral cortex than tonic firing, and bursts may activate neurons that are not activated by tonic firing...
Occupational noise, smoking, and a high body mass index are risk factors for age-related hearing impairment and moderate alcohol consumption is protective: a European population-based multicenter studyErik Fransen
Department of Medical Genetics, University of Antwerp, Universiteitsplein, 2610 Antwerp, Belgium
J Assoc Res Otolaryngol 9:264-76; discussion 261-3. 2008..Significant associations were found in the high as well as in the low frequencies. The results suggest that a healthy lifestyle can protect against age-related hearing impairment...
Tinnitus intensity dependent gamma oscillations of the contralateral auditory cortexElsa van der Loo
Brain Research centre Antwerp for Innovative and Interdisciplinary Neuromodulation BRAI 2 N, University Hospital Antwerp, Antwerp, Belgium
PLoS ONE 4:e7396. 2009..The present study aims to investigate the relation between objective gamma-band activity in the contralateral auditory cortex and subjective tinnitus loudness scores...
The difference between uni- and bilateral auditory phantom perceptSven Vanneste
BRAI2N, TRI and Department of Neurosurgery, University Hospital Antwerp, Belgium
Clin Neurophysiol 122:578-87. 2011..Tinnitus can be considered an auditory phantom percept, in which patients hear an internal sound in the absence of any external sound source, mimicking tonal memory. Tinnitus however can be perceived exclusively uni- or bilaterally...
A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosisIsabelle Schrauwen
Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
Am J Hum Genet 84:328-38. 2009..Consistent with the GWA data, expression of RELN was confirmed in the inner ear and in stapes footplate specimens. In conclusion, we provide evidence that implicates RELN in the pathogenesis of otosclerosis...
Primary and secondary auditory cortex stimulation for intractable tinnitusDirk De Ridder
Department of Neurosurgery and Otorhinolaryngology, University Hospital Antwerp, Antwerp, Belgium
ORL J Otorhinolaryngol Relat Spec 68:48-54; discussion 54-5. 2006....
Audiometric shape and presbycusisKelly Demeester
Department of Otolaryngology, University and University Hospital of Antwerp, Wilrijkstraat 10, 2650 Edegem, Antwerp, Belgium
Int J Audiol 48:222-32. 2009....
Comparison of 2 implantable bone conduction devices in patients with single-sided deafness using a daily alternating methodJolien Brigit Johan Desmet
Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Edegem, Belgium
Otol Neurotol 33:1018-26. 2012..Comparison of the auditory and subjective capabilities of 2 implantable bone conduction devices BAHA Divino sound processor (Divino) and the BAHA BP100 sound processor (BP100) using a daily alternating method...
Phase-shift treatment for tinnitus of cochlear originOlivier Meeus
University Department of Otorhinolaryngology and Head and Neck Surgery, Brain Research Center Antwerp for Innovative and Interdisciplinary Neuromodulation BRAI 2 N, Antwerp University Hospital UZA, University of Antwerp, Wilrijkstraat 10, 2650, Edegem, Antwerp, Belgium
Eur Arch Otorhinolaryngol 267:881-8. 2010..014). In conclusion, implementation of phase-shifting did not lead to significant sound cancelling. Our results are discussed and compared to previous studies investigating the effects of phase-out in tinnitus patients...
Phenotypic variability of patients homozygous for the GJB2 mutation 35delG cannot be explained by the influence of one major modifier geneNele Hilgert
Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
Eur J Hum Genet 17:517-24. 2009..Significantly associated SNPs may reflect a small modifying effect on the phenotype. Increasing the power of the study will be of greatest importance to confirm these results...
Hearing disability measured by the speech, spatial, and qualities of hearing scale in clinically normal-hearing and hearing-impaired middle-aged persons, and disability screening by means of a reduced SSQ (the SSQ5)Kelly Demeester
Department of Otolaryngology, University and University Hospital of Antwerp, Belgium
Ear Hear 33:615-6. 2012..In the second part of this study, the number of SSQ items was reduced to five to make this questionnaire available for routine usage in clinical settings and for screening purposes...
The neural network of phantom sound changes over time: a comparison between recent-onset and chronic tinnitus patientsSven Vanneste
TRI Tinnitus Clinic, Brai n, TRI and Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem, Belgium
Eur J Neurosci 34:718-31. 2011..These networks are both connected to the left parahippocampal area. Thus acute and chronic tinnitus are related to differential activity and connectivity in a network comprising the auditory cortices, insula, dACC and premotor cortex...
Repetitive transcranial magnetic stimulation frequency dependent tinnitus improvement by double cone coil prefrontal stimulationSven Vanneste
Brai n, TRI and Department of Neurosurgery, University Hospital Antwerp, Edegem, Belgium
J Neurol Neurosurg Psychiatry 82:1160-4. 2011..A double cone coil (DCC) with large angled windings has been developed to modulate deeper brain areas such as the dorsal and subcallosal anterior cingulate cortex...
Microvascular decompression for tinnitus: significant improvement for tinnitus intensity without improvement for distress. A 4-year limitDirk De Ridder
BRAI2N, TRI Tinnitus Clinic and Department of Neurosurgery, University Hospital Antwerp, Belgium
Neurosurgery 66:656-60. 2010..Decompressing the cochlear nerve may result in improvement in tinnitus if the auditory nerve is not too damaged for recovery. The aim of the study is to find a cut-off point for this recovery based on clinical data...
Do tonic and burst TMS modulate the lemniscal and extralemniscal system differentially?Dirk De Ridder
Dept of Neurosurgery, ENT, University Hospital Antwerp, Edegem, Belgium
Int J Med Sci 4:242-6. 2007..Burst stimulation is shown to be more powerful in activating the cerebral cortex than tonic stimulation and bursts may activate neurons that are not activated by tonic stimulations...
Transcutaneous electrical nerve stimulation (TENS) of upper cervical nerve (C2) for the treatment of somatic tinnitusSven Vanneste
Brai 2 n, TRI and Department of Neurosurgery, University Hospital Antwerp, Antwerp University, Wilrijkstraat 10, 2650, Edegem, Belgium
Exp Brain Res 204:283-7. 2010..Significant tinnitus suppression was found (P < 0.001). Only 17.9% (N = 43) of the patients with tinnitus responded to C2 TENS. They had an improvement of 42.92%, and six patients had a reduction of 100%...
Cochlear implantation as a durable tinnitus treatment in single-sided deafnessAndrea Kleine Punte
University Department Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Belgium
Cochlear Implants Int 12:S26-9. 2011....
Prevalence of leisure noise-induced tinnitus and the attitude toward noise in university studentsAnnick Gilles
University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Belgium
Otol Neurotol 33:899-906. 2012..The present study provides prevalence numbers for noise-induced tinnitus (NIT) in this group, the attitude toward loud music, and the factors influencing the use of hearing protection (HP)...
22q11.2 microduplication syndrome with congenital aural atresia: a family reportAn Boudewyns
Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
Otol Neurotol 33:674-80. 2012..2 microduplication. When outer ear abnormalities are encountered, an additional workup including audiometry and computed tomography with 3-D reconstructions is required...
Effect of rate control on speech production and intelligibility in dysarthriaGwen Van Nuffelen
Antwerp University Hospital, Edegem, Belgium
Folia Phoniatr Logop 62:110-9. 2010..The most effective methods were: alphabet board, hand tapping and pacing board. For the majority of speakers, the maximal decrease in speech rate was not associated with the maximal increase in intelligibility...
Impacts of unit-level nurse practice environment and burnout on nurse-reported outcomes: a multilevel modelling approachPeter Van Bogaert
Department of Nursing, University Hospital Antwerp, B 2650 Edegem, Belgium
J Clin Nurs 19:1664-74. 2010..To investigate impacts of practice environment factors and burnout at the nursing unit level on job outcomes and nurse-assessed quality of care in acute hospital nurses...
The differences in brain activity between narrow band noise and pure tone tinnitusSven Vanneste
Department of Neurosurgery, University Hospital Antwerp, BRAI2N, Tinnitus Research Institute, Edegem, Belgium
PLoS ONE 5:e13618. 2010..However, the observed changes show great variability, hence lacking a conclusive picture. One of the reasons might be the selection of inhomogeneous groups in data analysis...
Binaural hearing after cochlear implantation in subjects with unilateral sensorineural deafness and tinnitusKatrien Vermeire
University Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Antwerp, University of Antwerp, Antwerp, Belgium
Audiol Neurootol 14:163-71. 2009..The preliminary results of these 20 subjects suggest that cochlear implantation can improve hearing in people suffering from single-sided deafness combined with tinnitus...
Cytomegalovirus DNA detection in Guthrie cards: role in the diagnostic work-up of childhood hearing lossAn Boudewyns
Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Antwerp University, Antwerp, Belgium
Otol Neurotol 30:943-9. 2009..Polymerase chain reaction (PCR) analysis of dried blood samples on the Guthrie card has been proposed as a sensitive and specific method to screen for congenital CMV infection...
Phenotype-genotype correlations in otosclerosis: clinical features of OTSC2Frank Declau
Department of Otorhinolaryngology, Head and Neck Surgery and Communication Disorders, University of Antwerp, Antwerp, Belgium
Adv Otorhinolaryngol 65:114-8. 2007..Identifying a genetic susceptibility would allow us to dissect out possible environmental factors that prevent the expression of clinical otosclerosis in those that carry the mutated gene and yet retain normal hearing...
Reliability and clinical relevance of segmental analysis based on intelligibility assessmentGwen Van Nuffelen
Antwerp University Hospital, University of Antwerp, Belgium
Folia Phoniatr Logop 60:264-8. 2008..Secondly, the hypothesis that the degree of agreement for phoneme identification may depend on the intelligibility of the speaker is addressed...
Mapping tinnitus-related brain activation: an activation-likelihood estimation metaanalysis of PET studiesJae Jin Song
Brain, TRI and Department of Neurosurgery, University Hospital Antwerp, Antwerp, Belgium
J Nucl Med 53:1550-7. 2012....
Influence of sensory loss on the perception of verticality in stroke patientsWim Saeys
Artesis University College of Antwerp, Antwerp, Belgium
Disabil Rehabil 34:1965-70. 2012..The aim of this study was to investigate the relationship between somatosensory loss and perception of verticality in stroke patients suffering single-hemisphere lesions...
Vascular compression of the cochlear nerve and tinnitus: a pathophysiological investigationDirk De Ridder
TRI Tinnitus Clinic, BRAI2N and Department of Neurosurgery, University Hospital Antwerp, Edegem, Belgium
Acta Neurochir (Wien) 154:807-13. 2012..Chronic microvascular compressions of the eighth nerve induce a slowing down of signal transmission in the auditory nerve, electrophysiologically characterized by IPL I-III prolongation...
Different resting state brain activity and functional connectivity in patients who respond and not respond to bifrontal tDCS for tinnitus suppressionSven Vanneste
Brai n, TRI and Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium
Exp Brain Res 210:217-27. 2011..They also have a different functional connectivity between DLPFC and, respectively, the sgACC and parahippocampal area. These connectivities might explain the suppression effect for both tinnitus loudness and tinnitus-related distress...
Medialization thyroplasty: vocal outcome of silicone and titanium implantNora van Ardenne
Department of ENT, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium
Eur Arch Otorhinolaryngol 268:101-7. 2011..Both silicone and titanium medialization implants showed improvement of vocal outcome, the results of the titanium implant being superior...
The coding polymorphism T263I in TGF-beta1 is associated with otosclerosis in two independent populationsMelissa Thys
Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
Hum Mol Genet 16:2021-30. 2007....
Incapacitating unilateral tinnitus in single-sided deafness treated by cochlear implantationPaul Van de Heyning
Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Antwerp, University of Antwerp, Antwerp, Belgium
Ann Otol Rhinol Laryngol 117:645-52. 2008..This study assessed the effect of electrical stimulation via a CI on tinnitus in subjects with unilateral deafness and ipsilateral tinnitus who underwent implantation in an attempt to treat tinnitus with the CI...
Otitis media with effusion: an underestimated cause of hearing loss in infantsAn Boudewyns
Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
Otol Neurotol 32:799-804. 2011..Otitis media with effusion (OME) is the major reason for failure of neonatal hearing screening. However, little is known about the impact on hearing status of OME in infants during the first months of life...
Subjective benefits of sequential bilateral cochlear implantation in young children after 18 months of implant useFanny Scherf
University Department of ORL, Antwerp University Hospital, Faculty of Medicine, Antwerp University, Antwerp, Belgium
ORL J Otorhinolaryngol Relat Spec 71:112-21. 2009..To investigate the subjective benefits of bilateral cochlear implantation in 33 young children after 18 months of second implant use...
Theta, alpha and beta burst transcranial magnetic stimulation: brain modulation in tinnitusDirk De Ridder
Dept of Neurosurgery, ENT, University Hospital Antwerp, Edegem, Belgium
Int J Med Sci 4:237-41. 2007..The authors analyze whether burst TMS at theta (5 Hz), alpha (10 Hz) and beta (20 Hz) frequencies can temporarily suppress narrow band noise/white noise tinnitus, which has been demonstrated to be intractable to tonic stimulation...
Transcranial direct current stimulation in tinnitus patients: a systemic review and meta-analysisJae Jin Song
Brain, TRI and Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, Edegem, Belgium
ScientificWorldJournal 2012:427941. 2012..Therefore, tDCS may be a promising tool for tinnitus management. Future RCTs in a large series regarding the efficacy as well as the comparison between LTA- and bifrontal tDCS are recommended...
Hyoid expansion as a treatment for obstructive sleep apnea: a pilot studyEvert Hamans
Department of Otorhinolaryngology, University Hospital Antwerp, Edegem, Belgium
Sleep Breath 17:195-201. 2013..This study was conducted to evaluate the safety, efficacy and feasibility of hyoid expansion...
Randomized controlled trial of truncal exercises early after stroke to improve balance and mobilityWim Saeys
University of Antwerp, Antwerp, Belgium
Neurorehabil Neural Repair 26:231-8. 2012..Sitting balance and the ability to perform selective truncal movements are important predictors of functional outcome after stroke. However, few clinical trials have evaluated the effect of truncal exercises...
Visualizing out-of-body experience in the brainDirk De Ridder
Department of Neurosurgery and Ear, Nose, and Throat, University Hospital Antwerp, Antwerp University, Antwerp, Belgium
N Engl J Med 357:1829-33. 2007..We suggest that activation of these regions is the neural correlate of the disembodiment that is part of the out-of-body experience...
The influence of different speech processor and hearing aid settings on speech perception outcomes in electric acoustic stimulation patientsKatrien Vermeire
Dept ENT Universitar Ziekenhuis, Antwerp, Belgium
Ear Hear 29:76-86. 2008..These improvements in performance have been especially noted in noise. Often overlooked is that these outcomes may be influenced by the fitting parameters of both the cochlear implant and the hearing aid...
The contribution of GJB2 (Connexin 26) 35delG to age-related hearing impairment and noise-induced hearing lossEls Van Eyken
Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
Otol Neurotol 28:970-5. 2007..The common GJB2 (Connexin 26) 35delG mutation might contribute to the development of age-related hearing impairment (ARHI) and noise-induced hearing loss (NIHL)...
Influence of tonic and burst transcranial magnetic stimulation characteristics on acute inhibition of subjective tinnitusOlivier Meeus
University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
Otol Neurotol 30:697-703. 2009..The aim of our study is to investigate the stimulation characteristics of TMS in tinnitus patients, in particular the effect of tonic and burst stimulation of the superior temporal lobe...
Transcranial magnetic stimulation for tinnitus: influence of tinnitus duration on stimulation parameter choice and maximal tinnitus suppressionDirk De Ridder
Department of Neurosurgery and Otorhinolaryngology, University Hospital Antwerp, Belgium
Otol Neurotol 26:616-9. 2005..Transcranial magnetic stimulation (TMS) is a noninvasive method to modulate cortical reorganization and has been shown to be able to influence tinnitus perception...
Functional anatomy of the human cochlear nerve and its role in microvascular decompressions for tinnitusDirk De Ridder
Department of Neurosurgery and Otorhinolaryngology, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem, Antwerp, Belgium
Neurosurgery 54:381-8; discussion 388-90. 2004....
Body surface area in normal-weight, overweight, and obese adults. A comparison studyJohan Verbraecken
Department of Pulmonary Medicine, University Hospital Antwerp, 2650 Edegem, Belgium
Metabolism 55:515-24. 2006..Although Mosteller's formula is recommended based on its simplicity and suitability for laboratory and clinical work in adults, accuracy studies in whites with 3-dimensional one-pass whole-body scanning are needed...
Acute respiratory distress after upper airway obstruction following palatoplastyVera Saldien
UZA, Department of Anesthesiology, University Hospital of Antwerp, Wilrijkstraat 10, B 2650 Edegem, Belgium
Int J Pediatr Otorhinolaryngol 67:403-7. 2003..We recommend after palatoplasty a more than careful postoperative clinical observation to detect and treat postoperative obstruction and hypoxemia...
Continuous positive airway pressure therapy is associated with an increase in intraocular pressure in obstructive sleep apneaStefan Kiekens
Department of Ophthalmology, Antwerp University Hospital and University of Antwerp, Antwerp, Belgium
Invest Ophthalmol Vis Sci 49:934-40. 2008..In the present study, the influence of OSA and continuous positive airway pressure (CPAP) therapy on intraocular pressure (IOP) and ocular perfusion pressure (OPP) was examined...
Does intratympanic gadolinium injection predict efficacy of gentamicin partial chemolabyrinthectomy in Menière's disease patients?Gerd Claes
University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital UZA, University of Antwerp, Wilrijkstraat 10, 2650, Antwerp Edegem, Belgium
Eur Arch Otorhinolaryngol 269:413-8. 2012..However, based on these data, a correlation between the result of TT-ECoG and hydrops grading on MRI images can be suggested...
Suppression of the E-effect during the subjective visual and postural vertical test in healthy subjectsWim Saeys
Department of Otorhinolaryngology, Faculty of Medicine, University of Antwerp, Wilrijkstraat 10, 2650 Edegem, Belgium
Eur J Appl Physiol 109:297-305. 2010..It seems that SVV and SPV measurements are influenced by head-on-body and starting roll positions and has to be taken into account in further studies...
The Ménière's Disease Index: an objective correlate of Ménière's disease, based on audiometric and electrocochleographic dataGerd M E Claes
Antwerp University Research centre for Equilibrium and Aerospace, University Department of Otorhinolaryngology Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium
Otol Neurotol 32:887-92. 2011..The aim of our study is to determine which combination of audiometric and electrocochleographic measures correlates best with the clinical diagnosis of endolymphatic hydrops...
Cardiovascular implications in the treatment of obstructive sleep apneaOlivier M Vanderveken
Department of ENT, Head and Neck Surgery, University of Antwerp, University Hospital Antwerp, Wilrijkstraat 10, 2650, Edegem, Antwerp, Belgium
J Cardiovasc Transl Res 4:53-60. 2011..Electrical stimulation of the hypoglossal nerve is a new investigational therapy for patients with moderate to severe OSA. This new treatment option, if proven effective, may provide cardiovascular benefits secondary to treating OSA...
Remote tentorium meningioma causing sudden sensorineural deafnessDirk De Ridder
Department of Neurosurgery, University Hospital Antwerp, 2650 Edegem, Belgium
Surg Neurol 70:312-7; discussion 318. 2008..Sudden sensorineural deafness is a well-known symptom mostly of unknown etiology...
Administration of the combination clonazepam-Deanxit as treatment for tinnitusOlivier Meeus
University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital UZA, University of Antwerp, Antwerp, Belgium
Otol Neurotol 32:701-9. 2011..Present study investigates the combination of Deanxit and clonazepam (Rivotril) intake for relief of tinnitus complaints, respecting a double-blind placebo-controlled approach for Deanxit in a crossover setup...
GJB2 mutations and degree of hearing loss: a multicenter studyRikkert L Snoeckx
Department of Medical Genetics, University of Antwerp, Universiteitsplein 1, B 2610 Antwerp, Belgium
Am J Hum Genet 77:945-57. 2005..Two genotypes--35delG/R143W (median 105 dB) and 35delG/dela(GJB6-D13S1830) (median 108 dB)--had significantly more-severe HI than that of 35delG homozygotes...
Adjustable tongue advancement for obstructive sleep apnea: a pilot studyEvert Hamans
Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Antwerp, Antwerp, Belgium
Ann Otol Rhinol Laryngol 117:815-23. 2008..The present procedures addressing the hypopharynx are invasive and have substantial morbidity and limited efficacy...
Clinical practice: an approach to stridor in infants and childrenAn Boudewyns
Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem, Belgium
Eur J Pediatr 169:135-41. 2010....
The Darwinian plasticity hypothesis for tinnitus and painDirk De Ridder
Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium
Prog Brain Res 166:55-60. 2007..We will also review the literature regarding physiological and anatomical, as well as imaging data that support the existence of this hypothetical form of plasticity...
The effect of rate control on speech rate and intelligibility of dysarthric speechGwen Van Nuffelen
Department of Oto Rhino Laryngology, Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium
Folia Phoniatr Logop 61:69-75. 2009..This study investigated the effect of rate control methods (RCMs) on speaking rate (SR), articulation rate (AR), and intelligibility in dysarthric speakers...
Pulsatile tinnitus and the intrameatal vascular loop: why do we not hear our carotids?Dirk De Ridder
Department of Neurosurgery, University Hospital Antwerp, Antwerp, Belgium
Neurosurgery 57:1213-7; discussion 1213-7. 2005..If so, we should constantly hear the arterial pulsations of the carotid arteries passing through the petrous bone...
A novel Z-score-based method to analyze candidate genes for age-related hearing impairmentErik Fransen
Department of Medical Genetics, University of Antwerp, Belgium
Ear Hear 25:133-41. 2004..This method can be the basis of future, powerful studies to identify ARHI genes...
Practice environments and their associations with nurse-reported outcomes in Belgian hospitals: development and preliminary validation of a Dutch adaptation of the Revised Nursing Work IndexPeter Van Bogaert
Department of Nursing, University Hospital Antwerp, Operating Room, Wilrijkstraat 10, B 2650 Edegem, Belgium
Int J Nurs Stud 46:54-64. 2009..To study the relationship between nurse work environment, job outcomes and nurse-assessed quality of care in the Belgian context...
Audiometric analyses confirm a cochlear component, disproportional to age, in stapedial otosclerosisVedat Topsakal
Department of Otorhinolaryngology, Antwerp University Hospital UZA, Belgium
Otol Neurotol 27:781-7. 2006..To report the preoperative audiometric profile of surgically confirmed otosclerosis...
A new autosomal recessive form of Stickler syndrome is caused by a mutation in the COL9A1 geneGuy Van Camp
Department of Medical Genetics, University of Antwerp, Universiteitsplein 1, B 2610 Antwerp, Belgium
Am J Hum Genet 79:449-57. 2006..Mutation analysis of this gene is recommended in patients with Stickler syndrome with possible autosomal recessive inheritance...
GJB2 (connexin 26) mutations are not a major cause of hearing loss in the Indonesian populationRikkert L Snoeckx
Department of Medical Genetics, University of Antwerp, Universiteitsplein, Antwerp, Belgium
Am J Med Genet A 135:126-9. 2005..No recurrent disease-causing mutation could be detected in this Indonesian population. These findings are in contrast with the results obtained in other populations where GJB2 is a major cause of congenital recessive hearing loss...
