Paul Van de Heyning

Summary

Affiliation: University Hospital Antwerp
Country: Belgium

Publications

  1. ncbi request reprint Tinnitus: from cochlear to cortical
    P Van de Heyning
    Brain Research Institute, Antwerp Unversity Hospital of Innovative and Interdisciplinairy Neuromodulation, Belgium
    B-ENT 3:1-2. 2007
  2. ncbi request reprint Tinnitus: a multidisciplinary clinical approach
    P Van de Heyning
    University Department of Otorhinolaryngology and Head and Neck Surgery, University Multidisciplinary Tinnitus Centre of Antwerp, Antwerp University Hospital UZA, Faculty of Medicine, University of Antwerp, Belgium
    B-ENT 3:3-10. 2007
  3. doi request reprint Electric acoustic stimulation: a new era in prosthetic hearing rehabilitation
    Paul Van de Heyning
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Antwerp, University of Antwerp, Antwerp, Belgium
    Adv Otorhinolaryngol 67:1-5. 2010
  4. ncbi request reprint Surgical treatment of Meniere's disease
    Paul H Van de Heyning
    University Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium
    Curr Opin Neurol 18:23-8. 2005
  5. ncbi request reprint Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease
    C F J De Valck
    Antwerp University Research centre for Equilibrium and Aerospace, Univ Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital
    B-ENT 5:1-6. 2009
  6. doi request reprint Theta-gamma dysrhythmia and auditory phantom perception
    Dirk De Ridder
    BRAI2N, Tinnitus Research Initiative Clinic, and Department of Neurosurgery, University Hospital Antwerp, Belgium
    J Neurosurg 114:912-21. 2011
  7. ncbi request reprint Three-year postimplantation auditory outcomes in children with sequential bilateral cochlear implantation
    Fanny Scherf
    Department of Otorhinolaryngology, Antwerp University Hospital, Antwerp University, Edegem, Belgium
    Ann Otol Rhinol Laryngol 118:336-44. 2009
  8. doi request reprint Genotype-phenotype correlation for DFNA22: characterization of non-syndromic, autosomal dominant, progressive sensorineural hearing loss due to MYO6 mutations
    Vedat Topsakal
    Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
    Audiol Neurootol 15:211-20. 2010
  9. doi request reprint Dorsolateral prefrontal cortex transcranial magnetic stimulation and electrode implant for intractable tinnitus
    Dirk De Ridder
    Brai 2 n, University Hospital Antwerp, Antwerp, Belgium
    World Neurosurg 77:778-84. 2012
  10. ncbi request reprint Hospital nurse practice environment, burnout, job outcomes and quality of care: test of a structural equation model
    Peter Van Bogaert
    Department of Nursing, University Hospital Antwerp, Belgium
    J Adv Nurs 65:2175-85. 2009

Detail Information

Publications89

  1. ncbi request reprint Tinnitus: from cochlear to cortical
    P Van de Heyning
    Brain Research Institute, Antwerp Unversity Hospital of Innovative and Interdisciplinairy Neuromodulation, Belgium
    B-ENT 3:1-2. 2007
    ..Tinnitus is presented in view of translational research from research to clinical application...
  2. ncbi request reprint Tinnitus: a multidisciplinary clinical approach
    P Van de Heyning
    University Department of Otorhinolaryngology and Head and Neck Surgery, University Multidisciplinary Tinnitus Centre of Antwerp, Antwerp University Hospital UZA, Faculty of Medicine, University of Antwerp, Belgium
    B-ENT 3:3-10. 2007
    ..The psycho-acoustic characteristics and the influence on health-related quality of life is a compulsory complementary assessment to establish a complete picture of the patient...
  3. doi request reprint Electric acoustic stimulation: a new era in prosthetic hearing rehabilitation
    Paul Van de Heyning
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Antwerp, University of Antwerp, Antwerp, Belgium
    Adv Otorhinolaryngol 67:1-5. 2010
    ..EAS has led to a new era in prosthetic hearing rehabilitation providing new understanding of basic physiological, psychoacoustic and medical aspects of the inner ear...
  4. ncbi request reprint Surgical treatment of Meniere's disease
    Paul H Van de Heyning
    University Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium
    Curr Opin Neurol 18:23-8. 2005
    ..This review comprises new insights from and discusses the impact of recent medical publications on the surgical treatment of Meniere's disease...
  5. ncbi request reprint Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease
    C F J De Valck
    Antwerp University Research centre for Equilibrium and Aerospace, Univ Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital
    B-ENT 5:1-6. 2009
    ..Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease...
  6. doi request reprint Theta-gamma dysrhythmia and auditory phantom perception
    Dirk De Ridder
    BRAI2N, Tinnitus Research Initiative Clinic, and Department of Neurosurgery, University Hospital Antwerp, Belgium
    J Neurosurg 114:912-21. 2011
    ..These data suggest that thetagamma coupling as proposed by the thalamocortical dysrhythmia model might be causally related to a conscious auditory phantom percept...
  7. ncbi request reprint Three-year postimplantation auditory outcomes in children with sequential bilateral cochlear implantation
    Fanny Scherf
    Department of Otorhinolaryngology, Antwerp University Hospital, Antwerp University, Edegem, Belgium
    Ann Otol Rhinol Laryngol 118:336-44. 2009
    ..We report on the auditory abilities and speech performance in quiet and noise of 35 children with sequential bilateral cochlear implantation after 3 years of bilateral implant use...
  8. doi request reprint Genotype-phenotype correlation for DFNA22: characterization of non-syndromic, autosomal dominant, progressive sensorineural hearing loss due to MYO6 mutations
    Vedat Topsakal
    Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
    Audiol Neurootol 15:211-20. 2010
    ..The phenotypes of all hitherto reported DFNA22 families with mutations in the MYO6 gene have been studied and compared. It seems that genetic defects that spare the motor domain of the myosin VI protein have a milder phenotype...
  9. doi request reprint Dorsolateral prefrontal cortex transcranial magnetic stimulation and electrode implant for intractable tinnitus
    Dirk De Ridder
    Brai 2 n, University Hospital Antwerp, Antwerp, Belgium
    World Neurosurg 77:778-84. 2012
    ..It is characterized by gamma-band activity in the frontal cortex that can be visualized with the use of electroencephalography, magnetoencephalography, and functional magnetic resonance imaging (fMRI)...
  10. ncbi request reprint Hospital nurse practice environment, burnout, job outcomes and quality of care: test of a structural equation model
    Peter Van Bogaert
    Department of Nursing, University Hospital Antwerp, Belgium
    J Adv Nurs 65:2175-85. 2009
    ..The aim of the study was to investigate relationships between nurse practice environment, burnout, job outcomes and nurse-assessed quality of care...
  11. doi request reprint Bilateral dorsolateral prefrontal cortex modulation for tinnitus by transcranial direct current stimulation: a preliminary clinical study
    Sven Vanneste
    BRAI2N, TRI, Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium
    Exp Brain Res 202:779-85. 2010
    ..This was, however, not the case for tinnitus intensity. Our study supports the involvement of the prefrontal cortex in the pathophysiology of tinnitus...
  12. doi request reprint No evidence for association between the renin-angiotensin-aldosterone system and otosclerosis in a large Belgian-Dutch population
    Isabelle Schrauwen
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
    Otol Neurotol 30:1079-83. 2009
    ..In the current study, a replication study was done in a large Belgian-Dutch population to investigate whether this association could be replicated...
  13. doi request reprint Transcranial magnetic stimulation and extradural electrodes implanted on secondary auditory cortex for tinnitus suppression
    Dirk De Ridder
    BRAI2N, University Hospital Antwerp, Belgium
    J Neurosurg 114:903-11. 2011
    ....
  14. doi request reprint Clinical need for a Baha trial in patients with single-sided sensorineural deafness. Analysis of a Baha database of 196 patients
    Jolien Desmet
    Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Antwerp, Wilrijkstraat 10, Edegem, 2650, Antwerp, Belgium
    Eur Arch Otorhinolaryngol 269:799-805. 2012
    ..The authors advocate that all patients, suffering from SSD, should be offered the opportunity to try a Baha device as no factors could be found that determine the decision of a patient following the trial period...
  15. pmc Occupational noise, smoking, and a high body mass index are risk factors for age-related hearing impairment and moderate alcohol consumption is protective: a European population-based multicenter study
    Erik Fransen
    Department of Medical Genetics, University of Antwerp, Universiteitsplein, 2610 Antwerp, Belgium
    J Assoc Res Otolaryngol 9:264-76; discussion 261-3. 2008
    ..Significant associations were found in the high as well as in the low frequencies. The results suggest that a healthy lifestyle can protect against age-related hearing impairment...
  16. doi request reprint A splice-site mutation and overexpression of MYO6 cause a similar phenotype in two families with autosomal dominant hearing loss
    Nele Hilgert
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
    Eur J Hum Genet 16:593-602. 2008
    ..Most likely, the overexpression is caused by a mutation in an unidentified regulatory region of the gene. This study indicates that the inner ear hair cells are sensitive to changes in expression levels of MYO6...
  17. doi request reprint Burst stimulation of the auditory cortex: a new form of neurostimulation for noise-like tinnitus suppression
    Dirk De Ridder
    BRAI2N, University Hospital Antwerp, Edegem, Belgium
    J Neurosurg 112:1289-94. 2010
    ..Burst firing is shown to be more powerful in activating the cerebral cortex than tonic firing, and bursts may activate neurons that are not activated by tonic firing...
  18. pmc Association of bone morphogenetic proteins with otosclerosis
    Isabelle Schrauwen
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
    J Bone Miner Res 23:507-16. 2008
    ..We found significant association in both populations with BMP2 and BMP4, implicating these two genes in the pathogenesis of this disease...
  19. doi request reprint Bilateral electric acoustic stimulation: a comparison of partial and deep cochlear electrode insertion. A longitudinal case study
    Andrea Kleine Punte
    University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
    Adv Otorhinolaryngol 67:144-52. 2010
    ..The aims were to assess whether low-frequency hearing could be preserved after deep electrode insertion, as well as to assess the benefit of bilateral EAS surgery compared to monaural EAS...
  20. doi request reprint The difference between uni- and bilateral auditory phantom percept
    Sven Vanneste
    BRAI2N, TRI and Department of Neurosurgery, University Hospital Antwerp, Belgium
    Clin Neurophysiol 122:578-87. 2011
    ..Tinnitus can be considered an auditory phantom percept, in which patients hear an internal sound in the absence of any external sound source, mimicking tonal memory. Tinnitus however can be perceived exclusively uni- or bilaterally...
  21. pmc Tinnitus intensity dependent gamma oscillations of the contralateral auditory cortex
    Elsa van der Loo
    Brain Research centre Antwerp for Innovative and Interdisciplinary Neuromodulation BRAI 2 N, University Hospital Antwerp, Antwerp, Belgium
    PLoS ONE 4:e7396. 2009
    ..The present study aims to investigate the relation between objective gamma-band activity in the contralateral auditory cortex and subjective tinnitus loudness scores...
  22. ncbi request reprint Primary and secondary auditory cortex stimulation for intractable tinnitus
    Dirk De Ridder
    Department of Neurosurgery and Otorhinolaryngology, University Hospital Antwerp, Antwerp, Belgium
    ORL J Otorhinolaryngol Relat Spec 68:48-54; discussion 54-5. 2006
    ..We present the results of the first implanted electrodes on the primary and secondary auditory cortex after a successful TMS suppression...
  23. doi request reprint Audiometric shape and presbycusis
    Kelly Demeester
    Department of Otolaryngology, University and University Hospital of Antwerp, Wilrijkstraat 10, 2650 Edegem, Antwerp, Belgium
    Int J Audiol 48:222-32. 2009
    ....
  24. pmc A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosis
    Isabelle Schrauwen
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
    Am J Hum Genet 84:328-38. 2009
    ..Consistent with the GWA data, expression of RELN was confirmed in the inner ear and in stapes footplate specimens. In conclusion, we provide evidence that implicates RELN in the pathogenesis of otosclerosis...
  25. doi request reprint Tinnitus in a single-sided deaf ear reduces speech reception in the nontinnitus ear
    Griet Mertens
    University Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium
    Otol Neurotol 34:662-6. 2013
    ..Recently, we demonstrated that loudness of tinnitus in single-sided deafness (SSD) could be reduced dramatically by implanting and activating a cochlear implant (CI)...
  26. doi request reprint No cochlear dead regions detected in non-pulsatile tinnitus patients: an assessment with the threshold equalizing noise (sound pressure level) test
    Annick Gilles
    Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Belgium
    Noise Health 15:129-33. 2013
    ..This occurred in patients with high-frequency steeply sloping audiogram configurations. The present study does not support the TEN (SPL) test as a reliable tool for the detection of cochlear DR in a tinnitus population...
  27. doi request reprint Hyoid expansion as a treatment for obstructive sleep apnea: a pilot study
    Evert Hamans
    Department of Otorhinolaryngology, University Hospital Antwerp, Edegem, Belgium
    Sleep Breath 17:195-201. 2013
    ..This study was conducted to evaluate the safety, efficacy and feasibility of hyoid expansion...
  28. doi request reprint Does 'cochlear Ménière's disease' exist? An electrocochleographic and audiometric study
    Gerd M E Claes
    Department of Otolaryngology and Head and Neck Surgery, University of Antwerp, STATUA University of Antwerp Center of Statistics, Antwerp, Belgium
    Audiol Neurootol 18:63-70. 2013
    ..The recently reported Ménière's Disease Index (MDI) combines audiometric and electrocochleographic parameters in a multidimensional measure correlating with the clinical degrees of MD...
  29. doi request reprint Comparison of 2 implantable bone conduction devices in patients with single-sided deafness using a daily alternating method
    Jolien Brigit Johan Desmet
    Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Edegem, Belgium
    Otol Neurotol 33:1018-26. 2012
    ..Comparison of the auditory and subjective capabilities of 2 implantable bone conduction devices BAHA Divino sound processor (Divino) and the BAHA BP100 sound processor (BP100) using a daily alternating method...
  30. doi request reprint Phase-shift treatment for tinnitus of cochlear origin
    Olivier Meeus
    University Department of Otorhinolaryngology and Head and Neck Surgery, Brain Research Center Antwerp for Innovative and Interdisciplinary Neuromodulation BRAI 2 N, Antwerp University Hospital UZA, University of Antwerp, Wilrijkstraat 10, 2650, Edegem, Antwerp, Belgium
    Eur Arch Otorhinolaryngol 267:881-8. 2010
    ..014). In conclusion, implementation of phase-shifting did not lead to significant sound cancelling. Our results are discussed and compared to previous studies investigating the effects of phase-out in tinnitus patients...
  31. pmc Phenotypic variability of patients homozygous for the GJB2 mutation 35delG cannot be explained by the influence of one major modifier gene
    Nele Hilgert
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
    Eur J Hum Genet 17:517-24. 2009
    ..Significantly associated SNPs may reflect a small modifying effect on the phenotype. Increasing the power of the study will be of greatest importance to confirm these results...
  32. doi request reprint Comparison of sound processing strategies for osseointegrated bone conduction implants in mixed hearing loss: multiple-channel nonlinear versus single-channel linear processing
    Jolien B J Desmet
    University Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium
    Otol Neurotol 34:598-603. 2013
    ....
  33. ncbi request reprint On the necessity of full length electrical cochlear stimulation to suppress severe tinnitus in single-sided deafness
    Andrea Kleine Punte
    Antwerp University Hospital, Univ Dept of Otorhinolaryngology and Head and Neck Surgery, University of Antwerp, Wilrijkstraat 10, 2650 Edegem, Antwerp, Belgium
    Hear Res 295:24-9. 2013
    ..Discussion arises whether electrical stimulation near the round window (RW) is also able to reduce tinnitus...
  34. doi request reprint Hearing disability measured by the speech, spatial, and qualities of hearing scale in clinically normal-hearing and hearing-impaired middle-aged persons, and disability screening by means of a reduced SSQ (the SSQ5)
    Kelly Demeester
    Department of Otolaryngology, University and University Hospital of Antwerp, Belgium
    Ear Hear 33:615-6. 2012
    ..In the second part of this study, the number of SSQ items was reduced to five to make this questionnaire available for routine usage in clinical settings and for screening purposes...
  35. doi request reprint The neural network of phantom sound changes over time: a comparison between recent-onset and chronic tinnitus patients
    Sven Vanneste
    TRI Tinnitus Clinic, Brai n, TRI and Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem, Belgium
    Eur J Neurosci 34:718-31. 2011
    ..These networks are both connected to the left parahippocampal area. Thus acute and chronic tinnitus are related to differential activity and connectivity in a network comprising the auditory cortices, insula, dACC and premotor cortex...
  36. doi request reprint Transcutaneous electrical nerve stimulation (TENS) of upper cervical nerve (C2) for the treatment of somatic tinnitus
    Sven Vanneste
    Brai 2 n, TRI and Department of Neurosurgery, University Hospital Antwerp, Antwerp University, Wilrijkstraat 10, 2650, Edegem, Belgium
    Exp Brain Res 204:283-7. 2010
    ..Significant tinnitus suppression was found (P < 0.001). Only 17.9% (N = 43) of the patients with tinnitus responded to C2 TENS. They had an improvement of 42.92%, and six patients had a reduction of 100%...
  37. doi request reprint Microvascular decompression for tinnitus: significant improvement for tinnitus intensity without improvement for distress. A 4-year limit
    Dirk De Ridder
    BRAI2N, TRI Tinnitus Clinic and Department of Neurosurgery, University Hospital Antwerp, Belgium
    Neurosurgery 66:656-60. 2010
    ..Decompressing the cochlear nerve may result in improvement in tinnitus if the auditory nerve is not too damaged for recovery. The aim of the study is to find a cut-off point for this recovery based on clinical data...
  38. pmc Do tonic and burst TMS modulate the lemniscal and extralemniscal system differentially?
    Dirk De Ridder
    Dept of Neurosurgery, ENT, University Hospital Antwerp, Edegem, Belgium
    Int J Med Sci 4:242-6. 2007
    ..Burst stimulation is shown to be more powerful in activating the cerebral cortex than tonic stimulation and bursts may activate neurons that are not activated by tonic stimulations...
  39. doi request reprint Cochlear implantation as a durable tinnitus treatment in single-sided deafness
    Andrea Kleine Punte
    University Department Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Belgium
    Cochlear Implants Int 12:S26-9. 2011
    ....
  40. doi request reprint Repetitive transcranial magnetic stimulation frequency dependent tinnitus improvement by double cone coil prefrontal stimulation
    Sven Vanneste
    Brai n, TRI and Department of Neurosurgery, University Hospital Antwerp, Edegem, Belgium
    J Neurol Neurosurg Psychiatry 82:1160-4. 2011
    ..A double cone coil (DCC) with large angled windings has been developed to modulate deeper brain areas such as the dorsal and subcallosal anterior cingulate cortex...
  41. doi request reprint Comparing immediate transient tinnitus suppression using tACS and tDCS: a placebo-controlled study
    Sven Vanneste
    Brai n, TRI and Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem, Belgium
    Exp Brain Res 226:25-31. 2013
    ..This study provides additional insights into the role of DLPFC in tinnitus modulation as well as the intersection between tinnitus and affective/attentional processing...
  42. doi request reprint Prevalence of leisure noise-induced tinnitus and the attitude toward noise in university students
    Annick Gilles
    University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Belgium
    Otol Neurotol 33:899-906. 2012
    ..The present study provides prevalence numbers for noise-induced tinnitus (NIT) in this group, the attitude toward loud music, and the factors influencing the use of hearing protection (HP)...
  43. doi request reprint 22q11.2 microduplication syndrome with congenital aural atresia: a family report
    An Boudewyns
    Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
    Otol Neurotol 33:674-80. 2012
    ..Audiometry revealed a moderately severe conductive hearing loss in accordance with the clinical and computed tomography findings...
  44. doi request reprint Binaural hearing after cochlear implantation in subjects with unilateral sensorineural deafness and tinnitus
    Katrien Vermeire
    University Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Antwerp, University of Antwerp, Antwerp, Belgium
    Audiol Neurootol 14:163-71. 2009
    ..The preliminary results of these 20 subjects suggest that cochlear implantation can improve hearing in people suffering from single-sided deafness combined with tinnitus...
  45. doi request reprint Effect of rate control on speech production and intelligibility in dysarthria
    Gwen Van Nuffelen
    Antwerp University Hospital, Edegem, Belgium
    Folia Phoniatr Logop 62:110-9. 2010
    ..The most effective methods were: alphabet board, hand tapping and pacing board. For the majority of speakers, the maximal decrease in speech rate was not associated with the maximal increase in intelligibility...
  46. ncbi request reprint Phenotype-genotype correlations in otosclerosis: clinical features of OTSC2
    Frank Declau
    Department of Otorhinolaryngology, Head and Neck Surgery and Communication Disorders, University of Antwerp, Antwerp, Belgium
    Adv Otorhinolaryngol 65:114-8. 2007
    ..Identifying a genetic susceptibility would allow us to dissect out possible environmental factors that prevent the expression of clinical otosclerosis in those that carry the mutated gene and yet retain normal hearing...
  47. doi request reprint Impacts of unit-level nurse practice environment and burnout on nurse-reported outcomes: a multilevel modelling approach
    Peter Van Bogaert
    Department of Nursing, University Hospital Antwerp, B 2650 Edegem, Belgium
    J Clin Nurs 19:1664-74. 2010
    ..To investigate impacts of practice environment factors and burnout at the nursing unit level on job outcomes and nurse-assessed quality of care in acute hospital nurses...
  48. pmc The differences in brain activity between narrow band noise and pure tone tinnitus
    Sven Vanneste
    Department of Neurosurgery, University Hospital Antwerp, BRAI2N, Tinnitus Research Institute, Edegem, Belgium
    PLoS ONE 5:e13618. 2010
    ..However, the observed changes show great variability, hence lacking a conclusive picture. One of the reasons might be the selection of inhomogeneous groups in data analysis...
  49. doi request reprint Cytomegalovirus DNA detection in Guthrie cards: role in the diagnostic work-up of childhood hearing loss
    An Boudewyns
    Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Antwerp University, Antwerp, Belgium
    Otol Neurotol 30:943-9. 2009
    ..Polymerase chain reaction (PCR) analysis of dried blood samples on the Guthrie card has been proposed as a sensitive and specific method to screen for congenital CMV infection...
  50. doi request reprint Reliability and clinical relevance of segmental analysis based on intelligibility assessment
    Gwen Van Nuffelen
    Antwerp University Hospital, University of Antwerp, Belgium
    Folia Phoniatr Logop 60:264-8. 2008
    ..Secondly, the hypothesis that the degree of agreement for phoneme identification may depend on the intelligibility of the speaker is addressed...
  51. ncbi request reprint Influence of sensory loss on the perception of verticality in stroke patients
    Wim Saeys
    Artesis University College of Antwerp, Antwerp, Belgium
    Disabil Rehabil 34:1965-70. 2012
    ..The aim of this study was to investigate the relationship between somatosensory loss and perception of verticality in stroke patients suffering single-hemisphere lesions...
  52. doi request reprint Mapping tinnitus-related brain activation: an activation-likelihood estimation metaanalysis of PET studies
    Jae Jin Song
    Brain, TRI and Department of Neurosurgery, University Hospital Antwerp, Antwerp, Belgium
    J Nucl Med 53:1550-7. 2012
    ....
  53. doi request reprint Vascular compression of the cochlear nerve and tinnitus: a pathophysiological investigation
    Dirk De Ridder
    TRI Tinnitus Clinic, BRAI2N and Department of Neurosurgery, University Hospital Antwerp, Edegem, Belgium
    Acta Neurochir (Wien) 154:807-13. 2012
    ..Chronic microvascular compressions of the eighth nerve induce a slowing down of signal transmission in the auditory nerve, electrophysiologically characterized by IPL I-III prolongation...
  54. doi request reprint Different resting state brain activity and functional connectivity in patients who respond and not respond to bifrontal tDCS for tinnitus suppression
    Sven Vanneste
    Brai n, TRI and Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium
    Exp Brain Res 210:217-27. 2011
    ..They also have a different functional connectivity between DLPFC and, respectively, the sgACC and parahippocampal area. These connectivities might explain the suppression effect for both tinnitus loudness and tinnitus-related distress...
  55. doi request reprint Medialization thyroplasty: vocal outcome of silicone and titanium implant
    Nora van Ardenne
    Department of ENT, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium
    Eur Arch Otorhinolaryngol 268:101-7. 2011
    ..Both silicone and titanium medialization implants showed improvement of vocal outcome, the results of the titanium implant being superior...
  56. pmc Theta, alpha and beta burst transcranial magnetic stimulation: brain modulation in tinnitus
    Dirk De Ridder
    Dept of Neurosurgery, ENT, University Hospital Antwerp, Edegem, Belgium
    Int J Med Sci 4:237-41. 2007
    ..The authors analyze whether burst TMS at theta (5 Hz), alpha (10 Hz) and beta (20 Hz) frequencies can temporarily suppress narrow band noise/white noise tinnitus, which has been demonstrated to be intractable to tonic stimulation...
  57. doi request reprint Otitis media with effusion: an underestimated cause of hearing loss in infants
    An Boudewyns
    Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
    Otol Neurotol 32:799-804. 2011
    ..Otitis media with effusion (OME) is the major reason for failure of neonatal hearing screening. However, little is known about the impact on hearing status of OME in infants during the first months of life...
  58. ncbi request reprint Incapacitating unilateral tinnitus in single-sided deafness treated by cochlear implantation
    Paul Van de Heyning
    Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Antwerp, University of Antwerp, Antwerp, Belgium
    Ann Otol Rhinol Laryngol 117:645-52. 2008
    ..This study assessed the effect of electrical stimulation via a CI on tinnitus in subjects with unilateral deafness and ipsilateral tinnitus who underwent implantation in an attempt to treat tinnitus with the CI...
  59. ncbi request reprint The coding polymorphism T263I in TGF-beta1 is associated with otosclerosis in two independent populations
    Melissa Thys
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
    Hum Mol Genet 16:2021-30. 2007
    ....
  60. doi request reprint Subjective benefits of sequential bilateral cochlear implantation in young children after 18 months of implant use
    Fanny Scherf
    University Department of ORL, Antwerp University Hospital, Faculty of Medicine, Antwerp University, Antwerp, Belgium
    ORL J Otorhinolaryngol Relat Spec 71:112-21. 2009
    ..To investigate the subjective benefits of bilateral cochlear implantation in 33 young children after 18 months of second implant use...
  61. pmc Epidemiology of noise-induced tinnitus and the attitudes and beliefs towards noise and hearing protection in adolescents
    Annick Gilles
    University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem, Belgium
    PLoS ONE 8:e70297. 2013
    ..In addition the attitudes and beliefs towards noise and hearing protection were evaluated in order to explain the use/non-use of hearing protection in a young population...
  62. pmc Transcranial direct current stimulation in tinnitus patients: a systemic review and meta-analysis
    Jae Jin Song
    Brain, TRI and Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, Edegem, Belgium
    ScientificWorldJournal 2012:427941. 2012
    ..Therefore, tDCS may be a promising tool for tinnitus management. Future RCTs in a large series regarding the efficacy as well as the comparison between LTA- and bifrontal tDCS are recommended...
  63. doi request reprint Randomized controlled trial of truncal exercises early after stroke to improve balance and mobility
    Wim Saeys
    University of Antwerp, Antwerp, Belgium
    Neurorehabil Neural Repair 26:231-8. 2012
    ..Sitting balance and the ability to perform selective truncal movements are important predictors of functional outcome after stroke. However, few clinical trials have evaluated the effect of truncal exercises...
  64. ncbi request reprint The contribution of GJB2 (Connexin 26) 35delG to age-related hearing impairment and noise-induced hearing loss
    Els Van Eyken
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
    Otol Neurotol 28:970-5. 2007
    ..The common GJB2 (Connexin 26) 35delG mutation might contribute to the development of age-related hearing impairment (ARHI) and noise-induced hearing loss (NIHL)...
  65. ncbi request reprint Visualizing out-of-body experience in the brain
    Dirk De Ridder
    Department of Neurosurgery and Ear, Nose, and Throat, University Hospital Antwerp, Antwerp University, Antwerp, Belgium
    N Engl J Med 357:1829-33. 2007
    ..We suggest that activation of these regions is the neural correlate of the disembodiment that is part of the out-of-body experience...
  66. ncbi request reprint The influence of different speech processor and hearing aid settings on speech perception outcomes in electric acoustic stimulation patients
    Katrien Vermeire
    Dept ENT Universitar Ziekenhuis, Antwerp, Belgium
    Ear Hear 29:76-86. 2008
    ..These improvements in performance have been especially noted in noise. Often overlooked is that these outcomes may be influenced by the fitting parameters of both the cochlear implant and the hearing aid...
  67. doi request reprint Influence of tonic and burst transcranial magnetic stimulation characteristics on acute inhibition of subjective tinnitus
    Olivier Meeus
    University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
    Otol Neurotol 30:697-703. 2009
    ..The aim of our study is to investigate the stimulation characteristics of TMS in tinnitus patients, in particular the effect of tonic and burst stimulation of the superior temporal lobe...
  68. ncbi request reprint Acute respiratory distress after upper airway obstruction following palatoplasty
    Vera Saldien
    UZA, Department of Anesthesiology, University Hospital of Antwerp, Wilrijkstraat 10, B 2650 Edegem, Belgium
    Int J Pediatr Otorhinolaryngol 67:403-7. 2003
    ..We recommend after palatoplasty a more than careful postoperative clinical observation to detect and treat postoperative obstruction and hypoxemia...
  69. doi request reprint Continuous positive airway pressure therapy is associated with an increase in intraocular pressure in obstructive sleep apnea
    Stefan Kiekens
    Department of Ophthalmology, Antwerp University Hospital and University of Antwerp, Antwerp, Belgium
    Invest Ophthalmol Vis Sci 49:934-40. 2008
    ..In the present study, the influence of OSA and continuous positive airway pressure (CPAP) therapy on intraocular pressure (IOP) and ocular perfusion pressure (OPP) was examined...
  70. ncbi request reprint Functional anatomy of the human cochlear nerve and its role in microvascular decompressions for tinnitus
    Dirk De Ridder
    Department of Neurosurgery and Otorhinolaryngology, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem, Antwerp, Belgium
    Neurosurgery 54:381-8; discussion 388-90. 2004
    ....
  71. ncbi request reprint Transcranial magnetic stimulation for tinnitus: influence of tinnitus duration on stimulation parameter choice and maximal tinnitus suppression
    Dirk De Ridder
    Department of Neurosurgery and Otorhinolaryngology, University Hospital Antwerp, Belgium
    Otol Neurotol 26:616-9. 2005
    ..Transcranial magnetic stimulation (TMS) is a noninvasive method to modulate cortical reorganization and has been shown to be able to influence tinnitus perception...
  72. ncbi request reprint Body surface area in normal-weight, overweight, and obese adults. A comparison study
    Johan Verbraecken
    Department of Pulmonary Medicine, University Hospital Antwerp, 2650 Edegem, Belgium
    Metabolism 55:515-24. 2006
    ..Although Mosteller's formula is recommended based on its simplicity and suitability for laboratory and clinical work in adults, accuracy studies in whites with 3-dimensional one-pass whole-body scanning are needed...
  73. doi request reprint Does intratympanic gadolinium injection predict efficacy of gentamicin partial chemolabyrinthectomy in Menière's disease patients?
    Gerd Claes
    University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital UZA, University of Antwerp, Wilrijkstraat 10, 2650, Antwerp Edegem, Belgium
    Eur Arch Otorhinolaryngol 269:413-8. 2012
    ..However, based on these data, a correlation between the result of TT-ECoG and hydrops grading on MRI images can be suggested...
  74. doi request reprint Suppression of the E-effect during the subjective visual and postural vertical test in healthy subjects
    Wim Saeys
    Department of Otorhinolaryngology, Faculty of Medicine, University of Antwerp, Wilrijkstraat 10, 2650 Edegem, Belgium
    Eur J Appl Physiol 109:297-305. 2010
    ..It seems that SVV and SPV measurements are influenced by head-on-body and starting roll positions and has to be taken into account in further studies...
  75. doi request reprint Cardiovascular implications in the treatment of obstructive sleep apnea
    Olivier M Vanderveken
    Department of ENT, Head and Neck Surgery, University of Antwerp, University Hospital Antwerp, Wilrijkstraat 10, 2650, Edegem, Antwerp, Belgium
    J Cardiovasc Transl Res 4:53-60. 2011
    ..Electrical stimulation of the hypoglossal nerve is a new investigational therapy for patients with moderate to severe OSA. This new treatment option, if proven effective, may provide cardiovascular benefits secondary to treating OSA...
  76. doi request reprint Remote tentorium meningioma causing sudden sensorineural deafness
    Dirk De Ridder
    Department of Neurosurgery, University Hospital Antwerp, 2650 Edegem, Belgium
    Surg Neurol 70:312-7; discussion 318. 2008
    ..Sudden sensorineural deafness is a well-known symptom mostly of unknown etiology...
  77. doi request reprint Administration of the combination clonazepam-Deanxit as treatment for tinnitus
    Olivier Meeus
    University Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital UZA, University of Antwerp, Antwerp, Belgium
    Otol Neurotol 32:701-9. 2011
    ..Present study investigates the combination of Deanxit and clonazepam (Rivotril) intake for relief of tinnitus complaints, respecting a double-blind placebo-controlled approach for Deanxit in a crossover setup...
  78. doi request reprint The Ménière's Disease Index: an objective correlate of Ménière's disease, based on audiometric and electrocochleographic data
    Gerd M E Claes
    Antwerp University Research centre for Equilibrium and Aerospace, University Department of Otorhinolaryngology Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium
    Otol Neurotol 32:887-92. 2011
    ..The aim of our study is to determine which combination of audiometric and electrocochleographic measures correlates best with the clinical diagnosis of endolymphatic hydrops...
  79. pmc GJB2 mutations and degree of hearing loss: a multicenter study
    Rikkert L Snoeckx
    Department of Medical Genetics, University of Antwerp, Universiteitsplein 1, B 2610 Antwerp, Belgium
    Am J Hum Genet 77:945-57. 2005
    ..Two genotypes--35delG/R143W (median 105 dB) and 35delG/dela(GJB6-D13S1830) (median 108 dB)--had significantly more-severe HI than that of 35delG homozygotes...
  80. doi request reprint The effect of rate control on speech rate and intelligibility of dysarthric speech
    Gwen Van Nuffelen
    Department of Oto Rhino Laryngology, Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium
    Folia Phoniatr Logop 61:69-75. 2009
    ..This study investigated the effect of rate control methods (RCMs) on speaking rate (SR), articulation rate (AR), and intelligibility in dysarthric speakers...
  81. ncbi request reprint Pulsatile tinnitus and the intrameatal vascular loop: why do we not hear our carotids?
    Dirk De Ridder
    Department of Neurosurgery, University Hospital Antwerp, Antwerp, Belgium
    Neurosurgery 57:1213-7; discussion 1213-7. 2005
    ..If so, we should constantly hear the arterial pulsations of the carotid arteries passing through the petrous bone...
  82. doi request reprint Clinical practice: an approach to stridor in infants and children
    An Boudewyns
    Department of Otorhinolaryngology, Head and Neck Surgery, Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem, Belgium
    Eur J Pediatr 169:135-41. 2010
    ....
  83. ncbi request reprint Adjustable tongue advancement for obstructive sleep apnea: a pilot study
    Evert Hamans
    Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Antwerp, Antwerp, Belgium
    Ann Otol Rhinol Laryngol 117:815-23. 2008
    ..The present procedures addressing the hypopharynx are invasive and have substantial morbidity and limited efficacy...
  84. ncbi request reprint The Darwinian plasticity hypothesis for tinnitus and pain
    Dirk De Ridder
    Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, 2650, Edegem, Belgium
    Prog Brain Res 166:55-60. 2007
    ..We will also review the literature regarding physiological and anatomical, as well as imaging data that support the existence of this hypothetical form of plasticity...
  85. ncbi request reprint A novel Z-score-based method to analyze candidate genes for age-related hearing impairment
    Erik Fransen
    Department of Medical Genetics, University of Antwerp, Belgium
    Ear Hear 25:133-41. 2004
    ..Here we define and validate a quantitative trait value for ARHI, correcting for age and gender, to allow the genetic study of ARHI as a quantitative trait...
  86. pmc A new autosomal recessive form of Stickler syndrome is caused by a mutation in the COL9A1 gene
    Guy Van Camp
    Department of Medical Genetics, University of Antwerp, Universiteitsplein 1, B 2610 Antwerp, Belgium
    Am J Hum Genet 79:449-57. 2006
    ..Mutation analysis of this gene is recommended in patients with Stickler syndrome with possible autosomal recessive inheritance...
  87. ncbi request reprint Audiometric analyses confirm a cochlear component, disproportional to age, in stapedial otosclerosis
    Vedat Topsakal
    Department of Otorhinolaryngology, Antwerp University Hospital UZA, Belgium
    Otol Neurotol 27:781-7. 2006
    ..To report the preoperative audiometric profile of surgically confirmed otosclerosis...
  88. pmc Practice environments and their associations with nurse-reported outcomes in Belgian hospitals: development and preliminary validation of a Dutch adaptation of the Revised Nursing Work Index
    Peter Van Bogaert
    Department of Nursing, University Hospital Antwerp, Operating Room, Wilrijkstraat 10, B 2650 Edegem, Belgium
    Int J Nurs Stud 46:54-64. 2009
    ..To study the relationship between nurse work environment, job outcomes and nurse-assessed quality of care in the Belgian context...
  89. ncbi request reprint GJB2 (connexin 26) mutations are not a major cause of hearing loss in the Indonesian population
    Rikkert L Snoeckx
    Department of Medical Genetics, University of Antwerp, Universiteitsplein, Antwerp, Belgium
    Am J Med Genet A 135:126-9. 2005
    ..No recurrent disease-causing mutation could be detected in this Indonesian population. These findings are in contrast with the results obtained in other populations where GJB2 is a major cause of congenital recessive hearing loss...