P Renard

Summary

Affiliation: University of Namur
Country: Belgium

Publications

  1. ncbi Development of a sensitive multi-well colorimetric assay for active NFkappaB
    P Renard
    Laboratoire de Biologie et Biochimie Cellulaire, Facultes Universitaires Notre Dame de la Paix, 61 rue de Bruxelles, B 5000 Namur, Belgium
    Nucleic Acids Res 29:E21. 2001
  2. ncbi Is the effect of interleukin-1 on glutathione oxidation in cultured human fibroblasts involved in nuclear factor-kappaB activation?
    P Renard
    Laboratoire de Biochimie et de Biologie Cellulaire, Facultes Universitaires Notre Dame de la Paix, Namur, Belgium
    Antioxid Redox Signal 3:329-40. 2001
  3. ncbi mtCLIC is up-regulated and maintains a mitochondrial membrane potential in mtDNA-depleted L929 cells
    T Arnould
    Laboratoire de Biochimie et Biologie Cellulaire, University of Namur F U N D P, 61 rue de Bruxelles, 5000 Namur, Belgium
    FASEB J 17:2145-7. 2003
  4. ncbi CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation
    T Arnould
    Laboratoire de Biochimie et Biologie Cellulaire, University of Namur FUNDP, 61 rue de Bruxelles, B 5000 Namur, Belgium
    EMBO J 21:53-63. 2002
  5. ncbi Unbiased proteomic analysis of proteins interacting with the HIV-1 5'LTR sequence: role of the transcription factor Meis
    A Tacheny
    Laboratory of Biochemistry and Cell Biology URBC, NAmur Research Institute for LIfe Sciences NARILIS, University of Namur, 61 rue de Bruxelles, 5000 Namur, Belgium
    Nucleic Acids Res 40:e168. 2012
  6. ncbi Synthesis, cytotoxic activity, NMR study and stereochemical effects of some new pyrano[3,2-b]thioxanthen-6-ones and pyrano[2,3-c]thioxanthen-7-ones
    I K Kostakis
    Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens, Panepistimiopolis-Zografou, 17345, Athens, Greece
    Bioorg Med Chem 9:2793-802. 2001
  7. ncbi Antitumor agents. Synthesis and biological evaluation of new compounds related to podophyllotoxin, containing the 2,3-dihydro-1,4-benzodioxin system
    A S Capilla
    , , Universitat de Barcelona, Av. Diagonal 643, E-08028 Barcelona, Spain
    Eur J Med Chem 36:389-93. 2001
  8. ncbi Synthesis and cytotoxicity of artemisinin derivatives containing cyanoarylmethyl group
    J M Wu
    Department of Synthetic Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China
    Eur J Med Chem 36:469-79. 2001
  9. ncbi Synthesis and cytotoxic activity of benzopyranoxanthone analogues of benz
    C Sittisombut
    , UMR/CNRS, , Paris, France
    Chem Pharm Bull (Tokyo) 49:675-9. 2001
  10. ncbi 2,2-Dimethyl-2H-anthra[2,3-b]pyran-6,11-diones: a new class of cytotoxic compounds
    E Melliou
    Laboratory of Pharmacognosy, University of Athens, Greece
    Bioorg Med Chem 9:607-12. 2001

Collaborators

  • Thierry Arnould
  • S Michel
  • G Atassi
  • A Tacheny
  • L Payen
  • A S Capilla
  • I K Kostakis
  • A L Skaltsounis
  • D H Caignard
  • J M Wu
  • E Melliou
  • C Sittisombut
  • M Dieu
  • S Leonce
  • J Legault
  • G S Wu
  • J X Han
  • F Tillequin
  • P Magiatis
  • P Marakos
  • N Pouli
  • M D Pujol
  • S Mitaku
  • N Costes
  • B Pfeiffer
  • D Xiao
  • M Koch
  • Y Li
  • F Shan
  • E Mikros
  • J Ding
  • P Petrov
  • J Remacle
  • M E Mirault
  • C Carrier

Detail Information

Publications11

  1. ncbi Development of a sensitive multi-well colorimetric assay for active NFkappaB
    P Renard
    Laboratoire de Biologie et Biochimie Cellulaire, Facultes Universitaires Notre Dame de la Paix, 61 rue de Bruxelles, B 5000 Namur, Belgium
    Nucleic Acids Res 29:E21. 2001
    ..This assay is easy to use, non-radioactive, highly reproducible, specific for NFkappaB, more sensitive than regular radioactive gel shift and very convenient for high throughput screening...
  2. ncbi Is the effect of interleukin-1 on glutathione oxidation in cultured human fibroblasts involved in nuclear factor-kappaB activation?
    P Renard
    Laboratoire de Biochimie et de Biologie Cellulaire, Facultes Universitaires Notre Dame de la Paix, Namur, Belgium
    Antioxid Redox Signal 3:329-40. 2001
    ..Of the five antioxidants tested, only curcumin was able to inhibit IkappaBalpha degradation upstream and, hence, NF-kappaB DNA-binding activity and NF-kappaB-dependent expression of IL-6 downstream...
  3. ncbi mtCLIC is up-regulated and maintains a mitochondrial membrane potential in mtDNA-depleted L929 cells
    T Arnould
    Laboratoire de Biochimie et Biologie Cellulaire, University of Namur F U N D P, 61 rue de Bruxelles, 5000 Namur, Belgium
    FASEB J 17:2145-7. 2003
    ..These findings suggest that mtCLIC could be involved in mitochondrial membrane potential generation in mtDNA-depleted cells, a feature required to prevent apoptosis and to drive continuous protein import into mitochondria...
  4. ncbi CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation
    T Arnould
    Laboratoire de Biochimie et Biologie Cellulaire, University of Namur FUNDP, 61 rue de Bruxelles, B 5000 Namur, Belgium
    EMBO J 21:53-63. 2002
    ..Finally, our data suggest that phosphorylated CREB recruits p53 tumor suppressor protein, modifies its transcriptional activity and increases the expression of p21(Waf1/Cip1), a p53-regulated cyclin-dependent kinase inhibitor...
  5. ncbi Unbiased proteomic analysis of proteins interacting with the HIV-1 5'LTR sequence: role of the transcription factor Meis
    A Tacheny
    Laboratory of Biochemistry and Cell Biology URBC, NAmur Research Institute for LIfe Sciences NARILIS, University of Namur, 61 rue de Bruxelles, 5000 Namur, Belgium
    Nucleic Acids Res 40:e168. 2012
    ..Combined with an in silico analysis of the DNA sequence of interest, this approach provides a powerful approach to select the interacting candidates to validate functionally by classical approaches...
  6. ncbi Synthesis, cytotoxic activity, NMR study and stereochemical effects of some new pyrano[3,2-b]thioxanthen-6-ones and pyrano[2,3-c]thioxanthen-7-ones
    I K Kostakis
    Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens, Panepistimiopolis-Zografou, 17345, Athens, Greece
    Bioorg Med Chem 9:2793-802. 2001
    ..The conformation of the molecules was also investigated in an effort to correlate this parameter with the biological activity...
  7. ncbi Antitumor agents. Synthesis and biological evaluation of new compounds related to podophyllotoxin, containing the 2,3-dihydro-1,4-benzodioxin system
    A S Capilla
    , , Universitat de Barcelona, Av. Diagonal 643, E-08028 Barcelona, Spain
    Eur J Med Chem 36:389-93. 2001
    ..The bis(phenylthio) derivatives were considered as possible precursors for lignan lactones (11). The hydroxy-naphthalen 6 showed a significant antineoplastic activity...
  8. ncbi Synthesis and cytotoxicity of artemisinin derivatives containing cyanoarylmethyl group
    J M Wu
    Department of Synthetic Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China
    Eur J Med Chem 36:469-79. 2001
    ..This mechanism of action was quite different from that of the majority of cytotoxic compounds used in the chemotherapy of cancer. Compound 4b possessed better cytotoxicity than the other compounds...
  9. ncbi Synthesis and cytotoxic activity of benzopyranoxanthone analogues of benz
    C Sittisombut
    , UMR/CNRS, , Paris, France
    Chem Pharm Bull (Tokyo) 49:675-9. 2001
    ..cis-3,4-Diacetoxy-5-methoxy-2,2-dimethyl-3,4-dihydro-2H,6H-benzo[b]pyrano[2,3-i]xanthen-6-one, the most active among the new compounds, was more potent than acronycine in inhibiting the proliferation of L1210 murine leukemia cells...
  10. ncbi 2,2-Dimethyl-2H-anthra[2,3-b]pyran-6,11-diones: a new class of cytotoxic compounds
    E Melliou
    Laboratory of Pharmacognosy, University of Athens, Greece
    Bioorg Med Chem 9:607-12. 2001
    ..Certain compounds possess interesting activity against murine leukemia L-1210 cells. Relationships between the biological activity and the pyrano-ring conformations are discussed...
  11. ncbi Mitochondrial GPx1 decreases induced but not basal oxidative damage to mtDNA in T47D cells
    J Legault
    Unit of Health and Environment, CHUL Research Center and Laval University, Quebec, Canada
    Biochem Biophys Res Commun 272:416-22. 2000
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