E Minet

Summary

Affiliation: University of Namur
Country: Belgium

Publications

  1. pmc A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain
    Adrienne E McKee
    Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA
    BMC Dev Biol 5:14. 2005
  2. ncbi HIF1A gene transcription is dependent on a core promoter sequence encompassing activating and inhibiting sequences located upstream from the transcription initiation site and cis elements located within the 5'UTR
    E Minet
    Laboratoire de Biochimie et Biologie Cellulaire, Facultés Universitaires de la Paix, 61 rue de Bruxelles, Namur, 5000, Belgium
    Biochem Biophys Res Commun 261:534-40. 1999
  3. ncbi Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction
    E Minet
    Laboratoire de Biochimie et Biologie Cellulaire, Facultés Universitaires de la Paix, 61 rue de Bruxelles, 5000, Namur, Belgium
    FEBS Lett 460:251-6. 1999
  4. ncbi ERK activation upon hypoxia: involvement in HIF-1 activation
    E Minet
    Laboratoire de Biochimie et Biologie Cellulaire, Facultés Universitaires de la Paix, 61 rue de Bruxelles, 5000, Namur, Belgium
    FEBS Lett 468:53-8. 2000
  5. ncbi c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells
    E Minet
    Laboratoire de Biochimie et Biologie Cellulaire, FUNDP, 61 rue de Bruxelles, Namur, 5000, Belgium
    Exp Cell Res 265:114-24. 2001
  6. ncbi A model for the complex between the hypoxia-inducible factor-1 (HIF-1) and its consensus DNA sequence
    G Michel
    Laboratoire de Chimie Moleculaire Structurale, Facultes Universitaires, Notre Dame de la Paix, Namur, Belgium
    J Biomol Struct Dyn 18:169-79. 2000
  7. ncbi Transduction pathways involved in Hypoxia-Inducible Factor-1 phosphorylation and activation
    E Minet
    Laboratoire de Biochimie et Biologie Cellulaire, , 61 rue de Bruxelles, 5000 Namur, Belgium
    Free Radic Biol Med 31:847-55. 2001
  8. ncbi HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: role of MAP kinases
    C Michiels
    Laboratory of Biochemistry and Cellular Biology, University of Namur, Belgium
    IUBMB Life 52:49-53. 2001
  9. ncbi Accumulation of the pro-apoptotic factor Bak is controlled by antagonist factor Mcl-1 availability
    E Minet
    Laboratory of Biochemistry and Cellular Biology, University of Namur, 61 rue de Bruxelles, 5000, Namur, Belgium
    Apoptosis 11:1039-47. 2006

Collaborators

Detail Information

Publications9

  1. pmc A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain
    Adrienne E McKee
    Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA
    BMC Dev Biol 5:14. 2005
    ..Several RBPs with activities that are important for the proper function of adult brain have been identified, but how many RBPs exist and where these genes are expressed in the developing brain is uncharacterized...
  2. ncbi HIF1A gene transcription is dependent on a core promoter sequence encompassing activating and inhibiting sequences located upstream from the transcription initiation site and cis elements located within the 5'UTR
    E Minet
    Laboratoire de Biochimie et Biologie Cellulaire, Facultés Universitaires de la Paix, 61 rue de Bruxelles, Namur, 5000, Belgium
    Biochem Biophys Res Commun 261:534-40. 1999
    ..Finally, we demonstrate that HIF1A gene transcription is dependent on Sp1 binding sites and that the 5'UTR sequence also contains other important cis-acting elements...
  3. ncbi Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction
    E Minet
    Laboratoire de Biochimie et Biologie Cellulaire, Facultés Universitaires de la Paix, 61 rue de Bruxelles, 5000, Namur, Belgium
    FEBS Lett 460:251-6. 1999
    ..At last, we showed that Hsp90 activity is essential for HIF-1 activation in hypoxia since it is inhibited in the presence of geldanamycin. These results indicate that Hsp90 is a major regulator in HIF-1alpha activation...
  4. ncbi ERK activation upon hypoxia: involvement in HIF-1 activation
    E Minet
    Laboratoire de Biochimie et Biologie Cellulaire, Facultés Universitaires de la Paix, 61 rue de Bruxelles, 5000, Namur, Belgium
    FEBS Lett 468:53-8. 2000
    ..These results evidence the role of mitogen-activated protein kinase in the transcriptional response to hypoxia...
  5. ncbi c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells
    E Minet
    Laboratoire de Biochimie et Biologie Cellulaire, FUNDP, 61 rue de Bruxelles, Namur, 5000, Belgium
    Exp Cell Res 265:114-24. 2001
    ....
  6. ncbi A model for the complex between the hypoxia-inducible factor-1 (HIF-1) and its consensus DNA sequence
    G Michel
    Laboratoire de Chimie Moleculaire Structurale, Facultes Universitaires, Notre Dame de la Paix, Namur, Belgium
    J Biomol Struct Dyn 18:169-79. 2000
    ..From these results, we postulate that the specificity of HIF-1 toward its DNA sequence could be driven by the HIF-1alpha subunit. The predicted model will be verified by X-Ray currently ongoing...
  7. ncbi Transduction pathways involved in Hypoxia-Inducible Factor-1 phosphorylation and activation
    E Minet
    Laboratoire de Biochimie et Biologie Cellulaire, , 61 rue de Bruxelles, 5000 Namur, Belgium
    Free Radic Biol Med 31:847-55. 2001
    ..In this review, we summarize some of the latest advances describing the possible signaling pathways leading to HIF-1 phosphorylation and subsequent activation. The physiological relevance of these regulations is also discussed...
  8. ncbi HIF-1 and AP-1 cooperate to increase gene expression in hypoxia: role of MAP kinases
    C Michiels
    Laboratory of Biochemistry and Cellular Biology, University of Namur, Belgium
    IUBMB Life 52:49-53. 2001
    ..Both HIF-1 and AP-1 activation by hypoxia seems to involve members of the MAP kinase family. Here, we summarize the data indicating that ERK and JNK are needed for activation of HIF-1 and AP-1, respectively...
  9. ncbi Accumulation of the pro-apoptotic factor Bak is controlled by antagonist factor Mcl-1 availability
    E Minet
    Laboratory of Biochemistry and Cellular Biology, University of Namur, 61 rue de Bruxelles, 5000, Namur, Belgium
    Apoptosis 11:1039-47. 2006
    ..Based on these results, we propose that regulation of Mcl-1-Bak steochiometry is a control mechanism used as a checkpoint to prevent or allow entry into apoptosis...