P Michielsen

Summary

Affiliation: University Hospital Antwerp
Country: Belgium

Publications

  1. ncbi request reprint Hepatitis C: screening, treatment and prevention practical guidelines
    P Michielsen
    Department of Hepatogastroenterology, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem
    Acta Gastroenterol Belg 66:15-9. 2003
  2. ncbi request reprint Treatment of chronic hepatitis C in patients with human immunodeficiency virus (HIV) with weekly peginterferon alpha-2b plus ribavirin: a multi-centred Belgian study
    P Michielsen
    Division of Hepatogastroenterology, University Hospital Antwerp, Belgium
    Acta Gastroenterol Belg 72:389-93. 2009
  3. pmc Immunological mechanisms in the pathophysiology of non-alcoholic steatohepatitis
    Luisa Vonghia
    Department of Gastroenterology and Hepatology, University Hospital Antwerp, Wilrijkstraat 10, Edegem 2650, Belgium
    Int J Mol Sci 14:19867-90. 2013
  4. ncbi request reprint Does antiviral therapy reduce the risk of hepatocellular carcinoma in patients with chronic hepatitis C?
    P Michielsen
    Division of Gastroenterology and Hepatology, University Hospital, Faculty of Medicine, University of Antwerp, Antwerp, Belgium
    Minerva Gastroenterol Dietol 58:65-79. 2012
  5. ncbi request reprint Viral hepatitis B and hepatocellular carcinoma
    P Michielsen
    Division of Gastroenterology and Hepatology, University Hospital Antwerp, Belgium
    Acta Gastroenterol Belg 74:4-8. 2011
  6. ncbi request reprint Liver diseases in the older adult
    P Michielsen
    Division of Hepatogastroenterology, University Hospital Antwerp, Edegem, Belgium
    Acta Gastroenterol Belg 73:1-4. 2010
  7. ncbi request reprint Treatment of hepatitis C: impact on the virus, quality of life and the natural history
    P Michielsen
    Division of Gastroenterology and Hepatology, University Hospital of Antwerp, Wilrijkstraat 10, B 2650 Edegem, Belgium
    Acta Gastroenterol Belg 65:90-4. 2002
  8. ncbi request reprint Therapy of chronic hepatitis C in the setting of HIV co-infection
    P Michielsen
    University Hospital Antwerp, Wilrijkstraat 10, B 2650 Edegem
    Acta Gastroenterol Belg 68:86-91. 2005
  9. ncbi request reprint A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population
    A Verrijken
    Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, University of Antwerp, Belgium
    Obesity (Silver Spring) 21:2138-45. 2013
  10. doi request reprint Coinfection of hepatitis B and hepatitis delta virus in Belgium: a multicenter BASL study. Prospective epidemiology and comparison with HBV mono-infection
    E Ho
    Faculty of Medicine and Health Sciences, Laboratory Medicine Microbiology, Antwerp University Hospital, Antwerp, Edegem, Belgium
    J Med Virol 85:1513-7. 2013

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Hepatitis C: screening, treatment and prevention practical guidelines
    P Michielsen
    Department of Hepatogastroenterology, University Hospital Antwerp, Wilrijkstraat 10, 2650 Edegem
    Acta Gastroenterol Belg 66:15-9. 2003
  2. ncbi request reprint Treatment of chronic hepatitis C in patients with human immunodeficiency virus (HIV) with weekly peginterferon alpha-2b plus ribavirin: a multi-centred Belgian study
    P Michielsen
    Division of Hepatogastroenterology, University Hospital Antwerp, Belgium
    Acta Gastroenterol Belg 72:389-93. 2009
    ..We report the results of a multi-centred Belgian study evaluating efficacy and safety of peginterferon alpha-2b plus ribavirin in HIV-HCV co-infected patients without AIDS and without decompensated liver disease...
  3. pmc Immunological mechanisms in the pathophysiology of non-alcoholic steatohepatitis
    Luisa Vonghia
    Department of Gastroenterology and Hepatology, University Hospital Antwerp, Wilrijkstraat 10, Edegem 2650, Belgium
    Int J Mol Sci 14:19867-90. 2013
    ..This review focuses on the disturbances of the cells constituting the innate and adaptive immune system in the liver and in adipose tissue. ..
  4. ncbi request reprint Does antiviral therapy reduce the risk of hepatocellular carcinoma in patients with chronic hepatitis C?
    P Michielsen
    Division of Gastroenterology and Hepatology, University Hospital, Faculty of Medicine, University of Antwerp, Antwerp, Belgium
    Minerva Gastroenterol Dietol 58:65-79. 2012
    ..Further prospective studies using the more successful emerging treatments of chronic hepatitis C are to be conducted to evaluate the risk of HCC...
  5. ncbi request reprint Viral hepatitis B and hepatocellular carcinoma
    P Michielsen
    Division of Gastroenterology and Hepatology, University Hospital Antwerp, Belgium
    Acta Gastroenterol Belg 74:4-8. 2011
    ..With more potent antiviral drugs currently available (entecavir, tenofovir), long-term HBV DNA suppression is now possible with very low risk of drug resistance...
  6. ncbi request reprint Liver diseases in the older adult
    P Michielsen
    Division of Hepatogastroenterology, University Hospital Antwerp, Edegem, Belgium
    Acta Gastroenterol Belg 73:1-4. 2010
    ..Comprehensive geriatric assessment should be part of the preliminary evaluation of the older patient with liver disease...
  7. ncbi request reprint Treatment of hepatitis C: impact on the virus, quality of life and the natural history
    P Michielsen
    Division of Gastroenterology and Hepatology, University Hospital of Antwerp, Wilrijkstraat 10, B 2650 Edegem, Belgium
    Acta Gastroenterol Belg 65:90-4. 2002
    ..Recent data suggest that early interferon alpha treatment of patients with acute hepatitis C largely prevents the development of chronicity...
  8. ncbi request reprint Therapy of chronic hepatitis C in the setting of HIV co-infection
    P Michielsen
    University Hospital Antwerp, Wilrijkstraat 10, B 2650 Edegem
    Acta Gastroenterol Belg 68:86-91. 2005
    ..Similar predictive factors determine the success rate. The effect of prolonging therapy to 12 months in genotype 2/3 and to 18 months in early viral responders with genotypes 1/4 needs to be assessed in further studies...
  9. ncbi request reprint A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population
    A Verrijken
    Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, University of Antwerp, Belgium
    Obesity (Silver Spring) 21:2138-45. 2013
    ..We studied the association between the genes patatin-like phospholipase domain-containing protein 3 (PNPLA3) and apolipoprotein C3 (APOC3) and metabolic and histological parameters of NAFLD in obese patients...
  10. doi request reprint Coinfection of hepatitis B and hepatitis delta virus in Belgium: a multicenter BASL study. Prospective epidemiology and comparison with HBV mono-infection
    E Ho
    Faculty of Medicine and Health Sciences, Laboratory Medicine Microbiology, Antwerp University Hospital, Antwerp, Edegem, Belgium
    J Med Virol 85:1513-7. 2013
    ..6% (6/44) of the patients that were coinfected HBV and HDV were also infected with HCV. In conclusion, this study provided much needed epidemiological data on the current state of HDV infection in Belgium...
  11. doi request reprint The influence of laboratory-induced MELD score differences on liver allocation: more reality than myth
    J N Schouten
    Department of Gastroenterology and Hepatology, University Hospital Antwerp, Antwerp, Belgium
    Clin Transplant 26:E62-70. 2012
    ..Liver allocation in Eurotransplant (ET) is based on the MELD score. Interlaboratory MELD score differences in INR and creatinine determination have been reported. The clinical implication of this observation has not been demonstrated...
  12. doi request reprint Visceral adiposity and insulin resistance are independent predictors of the presence of non-cirrhotic NAFLD-related portal hypertension
    S Francque
    Department of Gastroenterology and Hepatology, Antwerp University Hospital, Antwerp, Belgium
    Int J Obes (Lond) 35:270-8. 2011
    ..As assessment of portal pressure is an invasive procedure, non-invasive parameters are needed to identify patients at risk...
  13. ncbi request reprint Abdominal ultrasonography by the hepato-gastroenterologist: problems, demands, solutions
    M Adler
    Division of Hepatogastroenterology, Hôpital Erasme ULB, Brussels, Belgium
    Acta Gastroenterol Belg 74:67-9. 2011
    ..Trainees in hepatogastroenterology should acquire the same theoretical and practical training as radiologists, they should be taught and supervised by competent instructors and have their expertise evaluated...
  14. ncbi request reprint The management of patients with mild hepatitis C
    C Verslype
    Department of Hepatology, University Hospital Gasthuisberg, Leuven, Belgium
    Acta Gastroenterol Belg 68:314-8. 2005
    ..Overall, the decision to initiate therapy should be individualized and based on the severity of the disease by liver biopsy, the potential of serious side effects, the probability of response and the motivation of the patient...
  15. ncbi request reprint Daily induction combination treatment with alpha 2b interferon and ribavirin or standard combination treatment in naive chronic hepatitis C patients. A multicentre randomized controlled trial
    H Van Vlierberghe
    Department of Gastroenterology and Hepatology, Ghent University Hospital, Ghent, Belgium
    J Viral Hepat 10:460-6. 2003
    ..Although an early virological response is observed more frequently in the induction treatment, end of treatment response and sustained responses did not differ...
  16. ncbi request reprint Guidelines for the management of chronic hepatitis C in patients infected after substance use
    G Robaeys
    Department of Gastroenterology and Hepatology, Ziekenhuis Oost Limburg, Genk, Schiepse Bos, 6, B 3600 Genk, Belgium
    Acta Gastroenterol Belg 68:38-45. 2005
  17. ncbi request reprint A pilot observational survey of hepatitis C in Belgium
    S De Maeght
    CH Jolimont, Haine Saint Paul
    Acta Gastroenterol Belg 71:4-8. 2008
    ..There is a lack of epidemiological data on hepatitis C (HCV) infected patients in Belgium. Therefore our purpose was to address this important question and to evaluate the feasibility of a national HCV observatory...
  18. ncbi request reprint Management and treatment of chronic hepatitis B virus: Belgian Association for the Study of the Liver (BASL) 2007 guidelines
    I Colle
    Department of Hepatology and Gastroenterology, Ghent University Hospital, Ghent, De Pintelaan 185, 9000 Gent, Belgium
    Acta Gastroenterol Belg 70:389-420. 2007
  19. ncbi request reprint The HepCar registry: report on a one-year registration program of hepatocellular carcinoma (HCC) in Belgium. What is daily practice in HCC?
    H Van Vlierberghe
    Department of Gastroenterology and Hepatology, Ghent University Hospital, Belgium
    Acta Gastroenterol Belg 68:403-11. 2005
    ..The HepCar registry is an initiative in which patients with hepatocellular carcinoma, their treatment and follow up are registered...
  20. ncbi request reprint HCV day: conclusions and requests of the Belgian Association for the Study of the Liver
    R Brenard
    Acta Gastroenterol Belg 65:119. 2002