Research Topics
| P P M M GeusensSummaryAffiliation: University Hospital Country: Belgium Publications
| Collaborators
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Detail Information
Publications
Strategies for treatment to prevent fragility fractures in postmenopausal womenPiet Geusens
Department of Internal Medicine, Subdivision of Rheumatology, Maastricht University Medical Center, Maastricht, The Netherlands
Best Pract Res Clin Rheumatol 23:727-40. 2009..Follow-up allows to check tolerance and safety, to optimise adherence and to decide about adequacy of response, duration and switching of therapy...
Bisphosphonates for postmenopausal osteoporosis: determining duration of treatmentPiet Geusens
Department of Internal Medicine, Subdivision of Rheumatology, Maastricht University Medical Centre, P Debyelaan 25, Maastricht, The Netherlands
Curr Osteoporos Rep 7:12-7. 2009..However, the usefulness of more than 5 years of treatment with BPs needs to be proved with higher levels of evidence-based medicine...- Naproxcinod, a new cyclooxygenase-inhibiting nitric oxide donator (CINOD)Piet Geusens
University Hasselt, University Hospital, The Netherlands
Expert Opin Biol Ther 9:649-57. 2009..AZD3582 (Naproxcinod) is the first in the class of CINODs... - Fracture prevention in menPiet Geusens
Department of Rheumatology, Maastricht University Medical Center, Maastricht, The Netherlands
Nat Rev Rheumatol 5:497-504. 2009..For men with severe osteoporosis, treatment with the anabolic agent teriparatide might be an effective option... - Bone: New guidelines for multistep fracture prevention in menPiet P M Geusens
Department of Internal Medicine, Subdivision of Rheumatology, Maastricht University Medical Centre, P O Box 616, 6200 MD Maastricht, The Netherlands
Nat Rev Rheumatol 8:568-70. 2012..Guidelines from the Endocrine Society for the management of osteoporosis and fracture risk in men are thus welcome, but further research into fracture prevention in men is required... 
Osteoimmunology and osteoporosisPiet Geusens
Department of Internal Medicine, Subdivision of Rheumatology, Maastricht University Medical Center, P, Debyelaan 25 Postbus 5800, 6202 AZ Maastricht, The Netherlands
Arthritis Res Ther 13:242. 2011..With the availability of new techniques to evaluate peri-inflammatory bone loss, osteitis, and erosions, peri-inflammatory bone changes are an exciting field for further research in the context of osteoimmunology...- Optimal use of vitamin D when treating osteoporosisJoop P W van den Bergh
Department of Internal Medicine, VieCuri Medical Centre Noord Limburg, PO Box 1926, 5900 BX, Venlo, The Netherlands
Curr Osteoporos Rep 9:36-42. 2011..Monitoring of 25(OH)D levels during follow-up and adjustment of vitamin D supplementation should be considered to reach and maintain adequate serum 25(OH)D levels of at least 50 nmol/L, preferably greater than 75 nmol/L in all patients... - Assessment of individual fracture risk: FRAX and beyondJoop P W van den Bergh
Department of Internal Medicine, VieCuri Medical Centre Noord Limburg, PO Box 1926, 5900 BX Venlo, The Netherlands
Curr Osteoporos Rep 8:131-7. 2010..FRAX may be used as the primary model, and in patients with recurrent fractures and falls the use of the Garvan model may be of additional value... - Timing of subsequent fractures after an initial fractureTineke A C M van Geel
Department of General Practice, Maastricht University Caphri, PO Box 616, 6200 MD Maastricht, The Netherlands
Curr Osteoporos Rep 8:118-22. 2010..These studies indicate the need for early action after an initial fracture with medical interventions that have an effect within a short term to reduce the preventable risks of subsequent fractures... - Risk of falling in patients with a recent fractureSvenhjalmar van Helden
Department of General Surgery Traumatology, University Hospital Maastricht, Maastricht, The Netherlands
BMC Musculoskelet Disord 8:55. 2007..The aim of this study was to assess the number of patients with falls and to identify fall risk factors that predict the risk of falling in the first three months after a clinical fracture... - Evaluation of patients with a recent clinical fracture and osteoporosis, a multidisciplinary approachBianca Dumitrescu
Department of Internal Medicine, Subdivision of Rheumatology, University Hospital, Maastricht, The Netherlands
BMC Musculoskelet Disord 9:109. 2008..Identifying and correcting these associated disorders will enhance treatment effect aimed at reducing the risk of subsequent fractures in patients older than 50 years... - Timing and risk factors for clinical fractures among postmenopausal women: a 5-year prospective studyAntonia C M van Geel
Care and Public Health Research Institute, Department of General Practice, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
BMC Med 4:24. 2006..Therefore, we assessed the risk and timing of incident clinical fractures, expressed as 5-year AR, in postmenopausal women... - Progress in osteoporosis and fracture prevention: focus on postmenopausal womenKenneth G Saag
Division of Clinical Immunology and Rheumatology, Center for Education and Research on Therapeutics, University of Alabama at Birmingham, 820 Faculty Office Tower, 510 20th Street South, Birmingham, AL 35294 3708, USA
Arthritis Res Ther 11:251. 2009..Emerging therapeutic options that target molecules of bone metabolism indicate that the next decade should offer even greater promise for further improving our diagnostic and treatment approaches... - Drug Insight: choosing a drug treatment strategy for women with osteoporosis-an evidence--based clinical perspectivePiet P Geusens
Department of Internal Medicine, Division of Rheumatology, University Hospital, P Debyelaan 25, Box 5800, 6202 AZ Maastricht, The Netherlands
Nat Clin Pract Rheumatol 4:240-8. 2008..Other determinants include the potential extraskeletal benefits and safety concerns of the drug, patient preferences and reimbursement issues... - Emerging treatments for postmenopausal osteoporosis - focus on denosumabPiet Geusens
Department of Internal Medicine, Subdivision of Rheumatology, Maastricht University Medical Center, Maastricht, The Netherlands
Clin Interv Aging 4:241-50. 2009.... - Integrating a gender dimension into osteoporosis and fracture risk researchPiet Geusens
Department of Internal Medicine Rheumatology, University Hospital, Maastricht, The Netherlands
Gend Med 4:S147-61. 2007..Sex (referring to the strict biological sense) and gender (referring to the sociocultural dimension) are major determinants of health and disease... - [Fracture prevention in postmenopausal women with osteoporosis by an annual infusion of zoledronic acid]P P M M Geusens
Academisch Ziekenhuis Maastricht, afd Interne Geneeskunde Reumatologie, Postbus 5800, 6202 AZ Maastricht
Ned Tijdschr Geneeskd 151:1445-8. 2007..Some examples of candidates for treatment with zoledronic acid would be patients with osteoporosis in whom oral treatment meets objections or who are hospitalised due to a fracture... - Osteoporosis: clinical featuresP Geusens
Internal Medicine and Rheumatology, University Hospital, Maastricht, The Netherlands
Minerva Med 99:167-75. 2008..In addition, many patients with fractures and osteoporosis have pre-existing contributors to secondary osteoporosis, many of which are correctable... - Osteoporosis and vertebral fractures in ankylosing spondylitisPiet Geusens
Division of Rheumatology, Department of Internal Medicine, University Hospital Maastricht, The Netherlands
Curr Opin Rheumatol 19:335-9. 2007..To review recent data, in the context of what is already known, about an increased risk of vertebral fractures in ankylosing spondylitis patients... - Impact of systematic implementation of a clinical case finding strategy on diagnosis and therapy of postmenopausal osteoporosisPiet Geusens
Biomedical Research Institute, University Hasselt, Hasselt, Belgium
J Bone Miner Res 23:812-8. 2008..We studied, in daily practice, the impact of systematic implementation of a previously validated clinical decision rule and fracture history on referral for bone densitometry (DXA) and drug prescription for osteoporosis... - Newer drug treatments: their effects on fracture preventionPiet Geusens
Biomedical Research Institute, University Hasselt, Campus Diepenbeek, Belgium
Best Pract Res Clin Rheumatol 19:983-9. 2005..Some new drugs that are being studied for their potential anti-fracture effects are listed... - The ratio of circulating osteoprotegerin to RANKL in early rheumatoid arthritis predicts later joint destructionP P Geusens
University Hospital, Maastricht, The Netherlands
Arthritis Rheum 54:1772-7. 2006.... - Review and evaluation of the Dutch guidelines for osteoporosisPiet P Geusens
Department of Rheumatology, University Hospital, Maastricht, The Netherlands
J Eval Clin Pract 12:539-48. 2006..These guidelines were evaluated for their validity and applicability... - The relationship among history of falls, osteoporosis, and fractures in postmenopausal womenPiet Geusens
Biomedical Research Institute, Limburgs Universitair Centrum, Diepenbeek, Belgium
Arch Phys Med Rehabil 83:903-6. 2002..To study the relative contribution of osteoporosis and falls to the occurrence of symptomatic fractures in postmenopausal women... - Bone turnover and hip bone mineral density in patients with sarcoidosisA Caroline Heijckmann
Department of Internal Medicine, Division of Endocrinology, University Hospital Maastricht, The Netherlands
Sarcoidosis Vasc Diffuse Lung Dis 24:51-8. 2007..We evaluated bone remodelling and bone mineral density (BMD) in patients with sarcoidosis and their dependency of disease-related and treatment-related factors... - Hip bone mineral density, bone turnover and risk of fracture in patients on long-term suppressive L-thyroxine therapy for differentiated thyroid carcinomaA Caroline Heijckmann
Department of Internal Medicine, Division of Endocrinology, University Hospital Maastricht, Maastricht, The Netherlands
Eur J Endocrinol 153:23-9. 2005..However, their effect on bone turnover, their contribution to bone mineral density (BMD) in the context of other clinical risk factors for osteoporosis and the prevalence of vertebral fractures is not well documented... - High prevalence of morphometric vertebral deformities in patients with inflammatory bowel diseaseAnna Caroline Heijckmann
Department of Internal Medicine, Division of Endocrinology, Hospital Bernhoven, Veghel, The Netherlands
Eur J Gastroenterol Hepatol 20:740-7. 2008..The objective of this study was to investigate the prevalence of vertebral deformities in inflammatory bowel disease patients and their relation with BMD and bone turnover... - Performance of risk indices for identifying low bone density in postmenopausal womenPiet Geusens
Biomedical Research Institute, Limburg University, Diepenbeek, Belgium
Mayo Clin Proc 77:629-37. 2002..The Osteoporosis Self-assessment Tool index is easiest to calculate and therefore may be most useful in clinical practice... - Baseline RANKL:OPG ratio and markers of bone and cartilage degradation predict annual radiological progression over 11 years in rheumatoid arthritisLilian H D van Tuyl
VU University Medical Center, Department of Rheumatology, De Boelelaan 1117, Amsterdam, The Netherlands
Ann Rheum Dis 69:1623-8. 2010.... - Belgian rheumatologists' perception on eligibility of RA patients for anti-TNF treatment matches more closely Dutch rather than Belgian reimbursement criteriaElke Geens
Department of Rheumatology, University Hospitals Leuven, Leuven, Belgium
Rheumatology (Oxford) 48:546-50. 2009..To assess discrepancies between perception of Belgian rheumatologists on eligibility of RA patients for anti-TNF treatment and Belgian reimbursement criteria and to compare Belgian with Dutch criteria and UK guidelines... - Quantitative ultrasound does not identify patients with an inflammatory disease at risk of vertebral deformitiesA Caroline Heijckmann
Department Internal Medicine, Division of Endocrinology, University Hospital Maastricht, The Netherlands
BMC Musculoskelet Disord 9:72. 2008.... - Clinical vertebral fractures in patients with ankylosing spondylitisDebby Vosse
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, Maastricht, The Netherlands
J Rheumatol 31:1981-5. 2004..To evaluate the prevalence and characteristics of clinically confirmed vertebral fractures (CVF) in patients with ankylosing spondylitis (AS)... - Factors affecting bone loss in female endurance athletes: a two-year follow-up studyLavienja A J L M Braam
Department of Biochemistry, University of Maastricht, Maastricht, The Netherlands
Am J Sports Med 31:889-95. 2003..Clinical Relevance: High-intensity training maintained over several years must be regarded in women as a risk factor for osteoporosis, and protocols for optimal treatment should be developed... - Falls and fractures in postmenopausal women: a reviewPiet Geusens
Biomedical Research Institute, Limburgs Universitair Centrum, Diepenbeek, Belgium
J Br Menopause Soc 9:101-6. 2003..Prospective studies are needed to evaluate whether a combined bone- and fall-directed therapy can further decrease the risk for fractures in patients with low bone density and an increased fall risk... - Efficacy and safety of infliximab in patients with ankylosing spondylitis: results of a randomized, placebo-controlled trial (ASSERT)Desiree van der Heijde
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 52:582-91. 2005..The objective of this multicenter, randomized, placebo-controlled study was to evaluate the efficacy and safety of infliximab in patients with AS... - Hip involvement in ankylosing spondylitis: epidemiology and risk factors associated with hip replacement surgeryBert Vander Cruyssen
Department of Rheumatology, Ghent University Hospital, B 9000 Gent, Belgium
Rheumatology (Oxford) 49:73-81. 2010..We aimed to describe the epidemiology of clinical and radiological hip involvement and define the risk factors for the hip replacement surgery in AS patients... - Markers for type II collagen breakdown predict the effect of disease-modifying treatment on long-term radiographic progression in patients with rheumatoid arthritisRobert Landewe
Department of Internal Medicine Rheumatology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Arthritis Rheum 50:1390-9. 2004.... - [Should the vitamin D level be determined for all fracture patients?]Joop van den Bergh
Universitair Medisch Centrum Maastricht, afd Interne Geneeskunde, subdivisie Endocrinologie, Maastricht, The Netherlands
Ned Tijdschr Geneeskd 154:A1758. 2010.... - Risk of new clinical fractures within 2 years following a fractureSvenhjalmar van Helden
Department of Trauma Surgery, Academic Hospital Maastricht, P Debijelaan 25, Postal number 5800, 6202 AZ, Maastricht, The Netherlands
Osteoporos Int 17:348-54. 2006..The study objective was to determine the absolute risk of subsequent clinical fractures within 2 years after a clinical fracture... - Analyses of immunosenescent markers in patients with autoimmune diseaseMarielle Thewissen
Hasselt University, Biomedical Research Institute and Transnationale Universiteit Limburg, School of Life Sciences, Agoralaan, Diepenbeek, Belgium, and Department of Clinical and Experimental Immunology, University Hospital Maastricht, The Netherlands
Clin Immunol 123:209-18. 2007..Both genetic factors, such as HLA DR4, and environmental factors, like CMV infection, might speed up this immunosenescence and contribute in this way to disease pathogenesis... - The fracture and osteoporosis outpatient clinic: an effective strategy for improving implementation of an osteoporosis guidelineSvenhjalmar van Helden
Department of General Surgery, Academic Hospital of Maastricht, Maastricht, The Netherlands
J Eval Clin Pract 13:801-5. 2007.... - Regarding the article "low BMD is less predictive than reported falls for future limb fractures in women across Europe: results from the European Prospective Osteoporosis Study", by Kaptoge et alE Pijpers
Bone 38:145; author reply 146-9. 2006 - [Clinical relevance of vertebral fractures]W F Lems
VU Medisch Centrum, afd Reumatologie, 3A64, Postbus 7057, 1007 MB Amsterdam
Ned Tijdschr Geneeskd 152:917-9. 2008..The disadvantage of the poorer image quality, particularly in the higher thoracic region, is amply compensated for by the efficiency and diagnostic convenience to the patients and reduced exposure to radiation...