Adrian Covaci

Summary

Affiliation: University of Antwerp
Country: Belgium

Publications

  1. doi request reprint Dancing on coke: smuggling cocaine dispersed in polyvinyl alcohol
    Alexander L N van Nuijs
    Toxicological Centre, University of Antwerp, Antwerp, Belgium
    J Forensic Sci 57:234-8. 2012
  2. doi request reprint Cocaine and metabolites in waste and surface water across Belgium
    Alexander L N van Nuijs
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp UA, Universiteitsplein 1, 2610 Antwerp, Belgium
    Environ Pollut 157:123-9. 2009
  3. doi request reprint Optimization and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for the determination of 13 top-prescribed pharmaceuticals in influent wastewater
    Alexander L N van Nuijs
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, Wilrijk, 2610 Antwerp, Belgium
    Anal Bioanal Chem 398:2211-22. 2010
  4. doi request reprint Sewage epidemiology--a real-time approach to estimate the consumption of illicit drugs in Brussels, Belgium
    Alexander L N van Nuijs
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp UA, Universiteitsplein 1, 2610 Antwerp, Belgium
    Environ Int 37:612-21. 2011
  5. doi request reprint Analysis of drugs of abuse in wastewater by hydrophilic interaction liquid chromatography-tandem mass spectrometry
    Alexander L N van Nuijs
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, Wilrijk, 2610, Antwerp, Belgium
    Anal Bioanal Chem 395:819-28. 2009
  6. doi request reprint A one year investigation of the occurrence of illicit drugs in wastewater from Brussels, Belgium
    Alexander L N van Nuijs
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
    J Environ Monit 13:1008-16. 2011
  7. doi request reprint Spatial and temporal variations in the occurrence of cocaine and benzoylecgonine in waste- and surface water from Belgium and removal during wastewater treatment
    Alexander L N van Nuijs
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp UA, Universiteitsplein 1, 2610 Antwerp, Belgium
    Water Res 43:1341-9. 2009
  8. ncbi request reprint Non-destructive pollution exposure assessment in the European hedgehog (Erinaceus europaeus): IV. Hair versus soil analysis in exposure and risk assessment of organochlorine compounds
    Helga D'Havé
    Department of Biology, Ecophysiology, Biochemistry and Toxicology Group, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Environ Pollut 145:861-8. 2007
  9. doi request reprint Can cocaine use be evaluated through analysis of wastewater? A nation-wide approach conducted in Belgium
    Alexander L N van Nuijs
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein, Antwerp, Belgium
    Addiction 104:734-41. 2009
  10. ncbi request reprint Nondestructive pollution exposure assessment in the European hedgehog (Erinaceus europaeus): III. Hair as an indicator of endogenous organochlorine compound concentrations
    Helga D'Havé
    Ecophysiology, Biochemistry and Toxicology Group, Department of Biology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Environ Toxicol Chem 25:158-67. 2006

Detail Information

Publications95

  1. doi request reprint Dancing on coke: smuggling cocaine dispersed in polyvinyl alcohol
    Alexander L N van Nuijs
    Toxicological Centre, University of Antwerp, Antwerp, Belgium
    J Forensic Sci 57:234-8. 2012
    ..Laboratory experiments showed that cocaine could be easily extracted from the PVA matrix. This case report reveals a new smuggling technique for the transportation of large amounts of cocaine from one country to another...
  2. doi request reprint Cocaine and metabolites in waste and surface water across Belgium
    Alexander L N van Nuijs
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp UA, Universiteitsplein 1, 2610 Antwerp, Belgium
    Environ Pollut 157:123-9. 2009
    ..The estimation of cocaine abuse through water analysis can be executed on regular basis without cooperation of patients. It also gives clear geographical information, while prevention campaigns can easily be implemented and evaluated...
  3. doi request reprint Optimization and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for the determination of 13 top-prescribed pharmaceuticals in influent wastewater
    Alexander L N van Nuijs
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, Wilrijk, 2610 Antwerp, Belgium
    Anal Bioanal Chem 398:2211-22. 2010
    ..In the future, this analytical method will be used to determine if there is a relationship between pharmaceutical sales figures and concentrations of these compounds in influent wastewater...
  4. doi request reprint Sewage epidemiology--a real-time approach to estimate the consumption of illicit drugs in Brussels, Belgium
    Alexander L N van Nuijs
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp UA, Universiteitsplein 1, 2610 Antwerp, Belgium
    Environ Int 37:612-21. 2011
    ..Therefore, efforts should be made to further optimize this approach in the future...
  5. doi request reprint Analysis of drugs of abuse in wastewater by hydrophilic interaction liquid chromatography-tandem mass spectrometry
    Alexander L N van Nuijs
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, Wilrijk, 2610, Antwerp, Belgium
    Anal Bioanal Chem 395:819-28. 2009
    ..The presence of ecgonine methyl ester in wastewater could be demonstrated for the first time. In the future, the new HILIC-MS/MS method will be applied to assess the use of DOAs in Belgium using the "sewage epidemiology" approach...
  6. doi request reprint A one year investigation of the occurrence of illicit drugs in wastewater from Brussels, Belgium
    Alexander L N van Nuijs
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
    J Environ Monit 13:1008-16. 2011
    ..For MTD, the ratio of parent compound/metabolite was in agreement with the excretion pattern, while for COC some deviations were observed, resulting from excretion pattern uncertainties, and stability and discharge issues...
  7. doi request reprint Spatial and temporal variations in the occurrence of cocaine and benzoylecgonine in waste- and surface water from Belgium and removal during wastewater treatment
    Alexander L N van Nuijs
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp UA, Universiteitsplein 1, 2610 Antwerp, Belgium
    Water Res 43:1341-9. 2009
    ..COC and BE were removed in the investigated WWTPs with a removal efficiency of >93%...
  8. ncbi request reprint Non-destructive pollution exposure assessment in the European hedgehog (Erinaceus europaeus): IV. Hair versus soil analysis in exposure and risk assessment of organochlorine compounds
    Helga D'Havé
    Department of Biology, Ecophysiology, Biochemistry and Toxicology Group, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Environ Pollut 145:861-8. 2007
    ....
  9. doi request reprint Can cocaine use be evaluated through analysis of wastewater? A nation-wide approach conducted in Belgium
    Alexander L N van Nuijs
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein, Antwerp, Belgium
    Addiction 104:734-41. 2009
    ..A recently introduced and direct nation-wide approach based on measurements of the major urinary excreted metabolite of cocaine, benzoylecgonine, in wastewater is proposed...
  10. ncbi request reprint Nondestructive pollution exposure assessment in the European hedgehog (Erinaceus europaeus): III. Hair as an indicator of endogenous organochlorine compound concentrations
    Helga D'Havé
    Ecophysiology, Biochemistry and Toxicology Group, Department of Biology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Environ Toxicol Chem 25:158-67. 2006
    ....
  11. ncbi request reprint Remarkable findings concerning PBDEs in the terrestrial top-predator red fox (Vulpes vulpes)
    Stefan Voorspoels
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium, Umweltbundesamt, P O Box 33 00 22, D 14191 Berlin, Germany
    Environ Sci Technol 40:2937-43. 2006
    ..Our data confirms unambiguously that BDE 209 does bioaccumulate in terrestrial top predators, such as the red fox...
  12. doi request reprint Brominated flame retardants and perfluorinated chemicals, two groups of persistent contaminants in Belgian human blood and milk
    Laurence Roosens
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Pollut 158:2546-52. 2010
    ..6 ng/g lw, respectively). An identical trend was observed for PFOS, but not for PFOA. We estimated that newborn exposure to BFRs and PFCs occurs predominantly post-natally, whereas placental transfer has a minor impact on the body burden...
  13. doi request reprint Novel brominated flame retardants: a review of their analysis, environmental fate and behaviour
    Adrian Covaci
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
    Environ Int 37:532-56. 2011
    ..Human exposure to NBFRs via different exposure pathways is discussed, and research gaps related to analysis, environmental sources, fate, and behaviour and human exposure are identified...
  14. doi request reprint Brominated flame retardants and polychlorinated biphenyls in fish from the river Scheldt, Belgium
    Laurence Roosens
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B 2610 Antwerp, Belgium
    Environ Int 34:976-83. 2008
    ..The calculated daily intake ranged from 3 ng to 330 ng PBDEs/day for normal eel consumers, but was as high as 9800 ng PBDEs/day for anglers, which may be considered at risk...
  15. doi request reprint Phthalate metabolites in obese individuals undergoing weight loss: Urinary levels and estimation of the phthalates daily intake
    Alin C Dirtu
    Toxicological Centre, University of Antwerp, Wilrijk, Antwerp, Belgium
    Environ Int 59:344-53. 2013
    ....
  16. ncbi request reprint Predatory bird species show different patterns of hydroxylated polychlorinated biphenyls (HO-PCBs) and polychlorinated biphenyls (PCBs)
    Veerle L B Jaspers
    Department of Biology, Campus Drie Eiken, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Sci Technol 42:3465-71. 2008
    ..Variation in the diet and species-specific accumulation and metabolism of PCBs are probably the most important causes for these differences. Correlations between HO-PCBs and their parent PCBs were only found significant for buzzards...
  17. ncbi request reprint Levels and distribution of polybrominated diphenyl ethers in various tissues of birds of prey
    Stefan Voorspoels
    Department of Pharmacy, Toxicology Division, University of Antwerp, CDE gebouw S, Universiteitsplein 1, B 2610 Wilrijk, Belgium
    Environ Pollut 144:218-27. 2006
    ..Passive (lipid content related) diffusion could not completely describe the PBDE tissue distribution, e.g. the lowest PBDE-load was measured in brain, a fairly lipid rich tissue...
  18. ncbi request reprint Levels and enantiomeric signatures of methyl sulfonyl PCB and DDE metabolites in livers of harbor porpoises (Phocoena phocoena) from the Southern North Sea
    Shaogang Chu
    Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Sci Technol 37:4573-8. 2003
    ..23) for the measured chiral MeSO2-PCB congeners was found in all samples. This result may suggest that one atropisomer may be preferentially formed in harbor porpoises or that the atropisomers are retained in a highly selective manner...
  19. doi request reprint Inter-species differences for polychlorinated biphenyls and polybrominated diphenyl ethers in marine top predators from the Southern North Sea: Part 2. Biomagnification in harbour seals and harbour porpoises
    Liesbeth Weijs
    Laboratory of Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Environ Pollut 157:445-51. 2009
    ....
  20. doi request reprint Exposure of the Flemish population to brominated flame retardants: model and risk assessment
    Laurence Roosens
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Int 36:368-76. 2010
    ..59ng/kgbwday and declines to approximately 1ng/kgbwday at later age. SigmaBDE(5) intake exhibited a different profile compared to SigmaHBCD with maximal levels for newborns and a decline to approximately 0.7ng/kgbwday at adulthood...
  21. ncbi request reprint Anthropogenic and naturally occurring organobrominated compounds in two deep-sea fish species from the Mediterranean Sea
    Adrian Covaci
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B 2610 Antwerp Wilrijk, Belgium
    Environ Sci Technol 42:8654-60. 2008
    ....
  22. doi request reprint Biomagnification of anthropogenic and naturally-produced organobrominated compounds in a marine food web from Sydney Harbour, Australia
    Sara Losada
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Int 35:1142-9. 2009
    ..9 and 3.4, respectively. This suggests that biomagnification occurs in the studied aquatic food chain for anthropogenic brominated compounds, but also for the naturally-produced organobromines...
  23. doi request reprint A screening of persistent organohalogenated contaminants in hair of East Greenland polar bears
    Veerle L B Jaspers
    Department of Biology, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Sci Total Environ 408:5613-8. 2010
    ..Further research with larger sample weights and sizes is therefore necessary to draw more definitive conclusions on the usefulness of hair for biomonitoring OHCs in polar bears and other fur mammals...
  24. doi request reprint Distribution of persistent organic pollutants in two different fat compartments from obese individuals
    Govindan Malarvannan
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Int 55:33-42. 2013
    ..To our knowledge, this study is the first to assess the relationship between POP levels in adipose tissue and markers of abdominal adiposity, determined by CT...
  25. doi request reprint Inter-species differences for polychlorinated biphenyls and polybrominated diphenyl ethers in marine top predators from the Southern North Sea: Part 1. Accumulation patterns in harbour seals and harbour porpoises
    Liesbeth Weijs
    Laboratory of Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Environ Pollut 157:437-44. 2009
    ..Harbour seals showed a higher ability to metabolize PCBs and PBDEs...
  26. doi request reprint The use of blue tit eggs as a biomonitoring tool for organohalogenated pollutants in the European environment
    Evi Van den Steen
    Laboratory of Ethology, Department of Biology, University of Antwerp, Universiteitsplein 1, Wilrijk, Belgium
    Sci Total Environ 408:1451-7. 2010
    ..In conclusion, our results suggest the usefulness of eggs from passerine birds as a biomonitoring tool for OHPs on a large geographical scale...
  27. doi request reprint Analytical and environmental aspects of the flame retardant tetrabromobisphenol-A and its derivatives
    Adrian Covaci
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B 2610 Wilrijk, Belgium
    J Chromatogr A 1216:346-63. 2009
    ..Much less analytical and environmental information exists for the various groups of TBBP-A derivatives which are largely used as additive flame retardants...
  28. ncbi request reprint Penguin colonies as secondary sources of contamination with persistent organic pollutants
    Laurence Roosens
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B 2610, Wilrijk, Belgium
    J Environ Monit 9:822-5. 2007
    ..This profile of PCB congeners closely matched profiles seen in penguin eggs or penguin blood...
  29. ncbi request reprint Brominated flame retardants and organochlorine pollutants in eggs of little owls (Athene noctua) from Belgium
    Veerle Jaspers
    Department of Biology, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Pollut 136:81-8. 2005
    ..No significant correlations were found between eggshell thickness and the analysed organohalogens...
  30. ncbi request reprint Evaluation of biochemical effects related to perfluorooctane sulfonic acid exposure in organohalogen-contaminated great tit (Parus major) and blue tit (Parus caeruleus) nestlings
    Philippe Tony Hoff
    Department of Biology, Research Unit Ecophysiology, Biochemistry and Toxicology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Chemosphere 61:1558-69. 2005
    ..None of the investigated organohalogen pollutants except for PFOS were suggested to be involved in the observed biological alterations...
  31. ncbi request reprint Levels and distribution of organochlorine pesticides, polychlorinated biphenyls and polybrominated diphenyl ethers in sediments and biota from the Danube Delta, Romania
    Adrian Covaci
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Pollut 140:136-49. 2006
    ....
  32. doi request reprint Bioaccumulation of micropollutants and biomarker responses in caged carp (Cyprinus carpio)
    Lieven Bervoets
    Ecophysiology, Biochemistry and Toxicology Group, Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Ecotoxicol Environ Saf 72:720-8. 2009
    ..This study shows that caged carp might be useful for the assessment of bioaccumulation and some effects of micropollutants in aquatic ecosystems...
  33. doi request reprint Levels and profiles of organochlorines and flame retardants in car and house dust from Kuwait and Pakistan: implication for human exposure via dust ingestion
    Nadeem Ali
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Int 55:62-70. 2013
    ..5ng/kg bw/day) it was only two-fold lower than the corresponding RfDs...
  34. doi request reprint A comparison of non-destructive sampling strategies to assess the exposure of white-tailed eagle nestlings (Haliaeetus albicilla) to persistent organic pollutants
    Igor Eulaers
    Ethology Research Group, Department of Biology, University of Antwerp, Wilrijk, Belgium
    Sci Total Environ 410:258-65. 2011
    ..Finally, we provide an integrated discussion on the use of body feathers and preen oil as non-destructive biomonitor strategies for nestling predatory birds...
  35. ncbi request reprint Levels and profiles of PCBs and OCPs in marine benthic species from the Belgian North Sea and the Western Scheldt Estuary
    Stefan Voorspoels
    Toxicological Centre, University of Antwerp UA, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Mar Pollut Bull 49:393-404. 2004
    ..000, p < 0.05), which suggests that the pollution can be classified as historical. However, because urban and industrial centres may still be emitting these compounds, more recent point and non-point sources cannot be ruled out...
  36. doi request reprint A first evaluation of the usefulness of feathers of nestling predatory birds for non-destructive biomonitoring of persistent organic pollutants
    Igor Eulaers
    University of Antwerp, Ethology Research Group, Department of Biology, Universiteitsplein 1, B 2610 Wilrijk, Belgium
    Environ Int 37:622-30. 2011
    ..In summary, our results indicate that the use of nestling feathers of northern raptors may be a valid and promising non-destructive biomonitoring strategy for POPs in their ecosystems...
  37. doi request reprint Maternal transfer of organochlorines and brominated flame retardants in blue tits (Cyanistes caeruleus)
    Evi Van den Steen
    Laboratory of Ethology, Department of Biology, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Int 35:69-75. 2009
    ..Maternal transfer in blue tits seemed to be selective for the more bioaccumulative and persistent congeners/compounds...
  38. doi request reprint Brominated flame retardants and organochlorines in the European environment using great tit eggs as a biomonitoring tool
    Evi Van den Steen
    Laboratory of Ethology, Department of Biology, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Int 35:310-7. 2009
    ..To our knowledge, this is the first study in which bird eggs were used as a monitoring tool for OHPs on such a large geographical scale...
  39. doi request reprint Biomagnification of naturally-produced methoxylated polybrominated diphenyl ethers (MeO-PBDEs) in harbour seals and harbour porpoises from the southern North Sea
    Liesbeth Weijs
    Laboratory for Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Environ Int 35:893-9. 2009
    ....
  40. doi request reprint Persistent organic pollutants and methoxylated PBDEs in harbour porpoises from the North Sea from 1990 until 2008: Young wildlife at risk?
    Liesbeth Weijs
    Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Sci Total Environ 409:228-37. 2010
    ....
  41. ncbi request reprint Polybrominated diphenyl ethers (PBDEs) in freshwater mussels and fish from Flanders, Belgium
    Adrian Covaci
    Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    J Environ Monit 7:132-6. 2005
    ..50) and most were statistically not significant (p > 0.05). This suggests that the exposure to contaminants arises from local sources possessing different signatures of PBDEs and organochlorine pollutants...
  42. ncbi request reprint Variation, levels and profiles of organochlorines and brominated flame retardants in great tit (Parus major) eggs from different types of sampling locations in Flanders (Belgium)
    Evi Van den Steen
    Department of Biology, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Int 34:155-61. 2008
    ..In conclusion, our results showed that the characteristics of a sampling location influence both the levels and profiles of PCBs, OCPs and PBDEs...
  43. doi request reprint Brominated flame retardants and perfluorinated compounds in indoor dust from homes and offices in Flanders, Belgium
    Wendy D'Hollander
    Laboratory for Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Chemosphere 81:478-87. 2010
    ..Calculated human exposure was below the reference dose values set by the US-EPA for BDE 209, HBCD and below the provisional tolerable daily intakes proposed by European Food Safety Authority for PFOS and PFOA...
  44. doi request reprint Accumulation of background levels of persistent organochlorine and organobromine pollutants through the soil-earthworm-hedgehog food chain
    Frouke Vermeulen
    Ecophysiology, Biochemistry and Toxicology Group U7, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Environ Int 36:721-7. 2010
    ..Our results suggest that POPs in tissues should be measured from an adequate number of individuals per population instead of relying on indirect estimates from levels in soil or prey items...
  45. doi request reprint Assessment of human exposure to Bisphenol-A, Triclosan and Tetrabromobisphenol-A through indoor dust intake in Belgium
    Tinne Geens
    Toxicological Center, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp Wilrijk, Belgium
    Chemosphere 76:755-60. 2009
    ..Food intake appears to be the major source of human exposure to BPA and TBBPA as dermal uptake through personal care products seems to be the major contributor for TCS...
  46. ncbi request reprint Occurrence of anthropogenic and naturally-produced organohalogenated compounds in tissues of Black Sea harbour porpoises
    Liesbeth Weijs
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Mar Pollut Bull 60:725-31. 2010
    ..Levels of PCBs and PBDEs in blubber were lower than concentrations reported for harbour porpoises from the North Sea, while concentrations of DDXs were higher...
  47. doi request reprint Body feathers as a potential new biomonitoring tool in raptors: a study on organohalogenated contaminants in different feather types and preen oil of West Greenland white-tailed eagles (Haliaeetus albicilla)
    Veerle L B Jaspers
    Department of Biology, University of Antwerp, Wilrijk, Belgium
    Environ Int 37:1349-56. 2011
    ..Washing with acetone therefore does not seem to be of great influence when relating to internal tissue concentrations. We recommend washing feathers only with distilled water in order to remove dirt and dust particles before analysis...
  48. doi request reprint Organohalogenated contaminants in eggs of rockhopper penguins (Eudyptes chrysocome) and imperial shags (Phalacrocorax atriceps) from the Falkland Islands
    Evi Van den Steen
    Laboratory of Ethology, Department of Biology, University of Antwerp, Universiteitsplein 1, Wilrijk, Belgium
    Sci Total Environ 409:2838-44. 2011
    ..Although our results showed that OHCs have also reached the Falkland Islands, concentrations were relatively low compared to other studies. However, future monitoring may be warranted to assess temporal trends of different OHCs...
  49. pmc Exposure to hexabromocyclododecanes (HBCDs) via dust ingestion, but not diet, correlates with concentrations in human serum: preliminary results
    Laurence Roosens
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Wilrijk, Belgium
    Environ Health Perspect 117:1707-12. 2009
    ..Because it is not chemically bound to the polymer, HBCD can migrate into the environment, contaminating indoor dust and foodstuff...
  50. doi request reprint Current exposure to persistent polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (p,p'-DDE) of Belgian students from food and dust
    Laurence Roosens
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Sci Technol 44:2870-5. 2010
    ..Instead, it is hypothesized that past and episodic higher current intakes are more important determinants of body burden than continuous background exposures at low levels...
  51. doi request reprint Brominated flame retardants in Belgian home-produced eggs: levels and contamination sources
    Adrian Covaci
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, B 2610 Wilrijk Antwerp, Belgium
    Sci Total Environ 407:4387-96. 2009
    ....
  52. doi request reprint Polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in human liver and adipose tissue samples from Belgium
    Adrian Covaci
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk Antwerp, Belgium
    Chemosphere 73:170-5. 2008
    ..64, p<0.01 for PCB 153 alone). Factors, such as exposure pathways (food, dust and air), rates of bioaccumulation, metabolism and elimination, influence the concentrations of PBDEs differently than those of PCBs in humans...
  53. ncbi request reprint Use of transplanted Zebra mussels (Dreissena polymorpha) to assess the bioavailability of microcontaminants in Flemish surface waters
    Lieven Bervoets
    Department of Biology, Ecophysiology, Biochemistry and Toxicology Group, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Environ Sci Technol 39:1492-505. 2005
    ..However, even at constant environmental concentrations a 10- to 100-fold variation in BAFs/BSAFs was observed. This study illustrated the need for biological monitoring since neither environmental..
  54. ncbi request reprint Comparison of accumulation of micropollutants between igenous and transplanted zebra mussels (Dreissena polymorpha)
    Lieven Bervoets
    Department of Biology, Ecophysiology, Biochemistry and Toxicology Group, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Environ Toxicol Chem 23:1973-83. 2004
    ..With this study, we were able to prove the applicability of transplanted mussels as a biomonitoring tool for the accumulation of pollutants over a wide range of pollution...
  55. ncbi request reprint Recent developments in the analysis of brominated flame retardants and brominated natural compounds
    Adrian Covaci
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B 2610 Wilrijk, Belgium
    J Chromatogr A 1153:145-71. 2007
    ..These compounds were generally identified during the routine analysis of BFRs and have received little attention until recently. For each topic, an overview is presented of its current status...
  56. ncbi request reprint Biomagnification of PBDEs in three small terrestrial food chains
    Stefan Voorspoels
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Sci Technol 41:411-6. 2007
    ..Not all top-predators will give a representative reflection of the pollution of their habitat, but confounding factors, such as metabolism, can influence the results to a great extent and can therefore lead to misinterpretations...
  57. doi request reprint Effects of laying order and experimentally increased egg production on organic pollutants in eggs of a terrestrial songbird species, the great tit (Parus major)
    Evi Van den Steen
    Department of Biology, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Sci Total Environ 407:4764-70. 2009
    ..To our knowledge, this is the first study in which the impact of an experimentally increased clutch size on the levels and profiles of contaminants in eggs has been investigated...
  58. doi request reprint An exposure study with polybrominated diphenyl ethers (PBDEs) in female European starlings (Sturnus vulgaris): toxicokinetics and reproductive effects
    Evi Van den Steen
    Laboratory of Ethology, Department of Biology, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Pollut 157:430-6. 2009
    ..In addition, egg weight and volume were significantly higher in the exposed group. These results suggest that, at the investigated exposure levels (150 microg sum PBDEs/bird), PBDEs may have a negative effect on reproductive performance...
  59. doi request reprint Downsides of the recycling process: harmful organic chemicals in children's toys
    Alin C Ionas
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Int 65:54-62. 2014
    ..Most likely, recycled materials are an important source of these additives in toys and therefore, their (re)use in products for children should be subject to stricter restrictions. ..
  60. doi request reprint Can starling eggs be useful as a biomonitoring tool to study organohalogenated contaminants on a worldwide scale?
    Marcel Eens
    Laboratory of Ethology, Department of Biology, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Int 51:141-9. 2013
    ....
  61. doi request reprint "Novel" brominated flame retardants in Belgian and UK indoor dust: implications for human exposure
    Nadeem Ali
    Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk Antwerp, Belgium
    Chemosphere 83:1360-5. 2011
    ..This study documents the presence of NBFRs in indoor environments, and emphasizes the need to evaluate the health implications of exposure to such chemicals...
  62. doi request reprint Occurrence of alternative flame retardants in indoor dust from New Zealand: indoor sources and human exposure assessment
    Nadeem Ali
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Chemosphere 88:1276-82. 2012
    ....
  63. doi request reprint Concentrations of chlorinated and brominated contaminants and their metabolites in serum of harbour seals and harbour porpoises
    Liesbeth Weijs
    Laboratory of Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Environ Int 35:842-50. 2009
    ..HO-PBDEs were not found in any species. In general, harbour seals accumulate less compounds and have mostly lower concentrations than harbour porpoises possibly as a result of a better developed metabolism...
  64. doi request reprint Physiologically based pharmacokinetic (PBPK) models for lifetime exposure to PCB 153 in male and female harbor porpoises (Phocoena phocoena): model development and evaluation
    Liesbeth Weijs
    Laboratory of Ecophysiology, Biochemistry and Toxicology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Environ Sci Technol 44:7023-30. 2010
    ..These PBPK models are capable of simulating the bioaccumulation of PCB 153 during the entire life span of approximately 20 years of the harbor porpoises...
  65. ncbi request reprint Microcontaminant accumulation, physiological condition and bilateral asymmetry in zebra mussels (Dreissena polymorpha) from clean and contaminated surface waters
    Judith Voets
    Laboratory for Ecophysiology, Biochemistry and Toxicology, Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Aquat Toxicol 79:213-25. 2006
    ....
  66. doi request reprint Occurrence of endocrine disrupting compounds in tissues and body fluids of Belgian dairy cows and its implications for the use of the cow as a model to study endocrine disruption
    Evi M L Petro
    Gamete Research Center, Laboratory for Veterinary Physiology, Department of Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Sci Total Environ 408:5423-8. 2010
    ....
  67. ncbi request reprint Polybrominated diphenyl ethers in marine species from the Belgian North Sea and the Western Scheldt Estuary: levels, profiles, and distribution
    Stefan Voorspoels
    Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Sci Technol 37:4348-57. 2003
    ..Some species, such as dab, plaice bib, and whiting, showed preferential accumulation of PBDEs in the liver. Higher brominated congeners in general showed higher affinity for liver than for muscle tissue...
  68. ncbi request reprint PBDEs in marine and freshwater sediments from Belgium: levels, profiles and relations with biota
    Stefan Voorspoels
    Toxicological Center, University of Antwerp U A, Universiteitsplein 1, 2610 Wilrijk, Belgium
    J Environ Monit 6:914-8. 2004
    ..BDE 183 and 209 could not be quantified in biota, although these congeners were undoubtedly present in the sediments. This raises questions about the bioavailability of these congeners in the environment...
  69. ncbi request reprint Analysis of cocaine and its principal metabolites in waste and surface water using solid-phase extraction and liquid chromatography-ion trap tandem mass spectrometry
    Adriana Gheorghe
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium
    Anal Bioanal Chem 391:1309-19. 2008
    ..The degradation of COC was minimal at -20 degrees C and pH = 2, but it was substantial at +20 degrees C and pH = 6. The validated method was applied to a set of waste and surface water samples collected in Belgium...
  70. pmc Can predatory bird feathers be used as a non-destructive biomonitoring tool of organic pollutants?
    Veerle L B Jaspers
    University of Antwerp, Department of Biology, Campus Drie Eiken, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Biol Lett 2:283-5. 2006
    ..84 when excluding 17 starved birds). Our findings provide the first indication that feathers of predatory birds could be useful in non-destructive biomonitoring of organic pollutants, although further validation may be necessary...
  71. doi request reprint Interspecific differences in concentrations and congener profiles of chlorinated and brominated organic pollutants in three insectivorous bird species
    Tom Dauwe
    Department of Biology, University of Antwerp, Universiteitsplein 1, B2610 Antwerp, Belgium
    Environ Int 35:369-75. 2009
    ..The high p,p'-DDT/p,p'-DDE ratio has previously been described in lapwings, which suggests that low p,p'-DDE accumulation in eggs might be inherent for this species...
  72. ncbi request reprint Spatial variations in the levels and isomeric patterns of PBDEs and HBCDs in the European eel in Flanders
    Laurence Roosens
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium
    Environ Int 36:415-23. 2010
    ..Intakes of those risk groups were higher in comparison with average consumers and were above reference doses described in literature which may induce adverse effects...
  73. doi request reprint Analytical characteristics of several new brominated flame retardants
    Tinne Geens
    Toxicological Center, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, Antwerp, Belgium
    Talanta 81:1865-9. 2010
    ..25mm x 0.10microm DB-5 column. A very low detection frequency of the investigated new BFRs in selected Belgian indoor dust samples (n=20) was found, suggesting that these alternate BFRs are only slowly replacing PBDEs in consumer goods...
  74. ncbi request reprint Hair as an indicator of endogenous tissue levels of brominated flame retardants in mammals
    Helga D'Havé
    Ecophysiology, Biochemistry and Toxicology Group, Department of Biology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Environ Sci Technol 39:6016-20. 2005
    ..37 < r < 0.78). The present study demonstrated that hair is a suitable indicator of PBDE exposure in terrestrial mammals which can be used in nondestructive monitoring schemes...
  75. doi request reprint Endocrine disrupting, haematological and biochemical effects of polybrominated diphenyl ethers in a terrestrial songbird, the European starling (Sturnus vulgaris)
    Evi Van den Steen
    Laboratory of Ethology, Department of Biology, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Sci Total Environ 408:6142-7. 2010
    ..All together, our results suggest that European starlings, similar to other passerine species, may be less sensitive to the effects of organohalogenated pollutants, such as PBDEs, than other bird species...
  76. ncbi request reprint Fast analysis of decabrominated diphenyl ether using low-pressure gas chromatography-electron-capture negative ionization mass spectrometry
    Alin C Dirtu
    Toxicological Center, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    J Chromatogr A 1186:295-301. 2008
    ..The obtained concentrations of BDE-209 (range 8-292 ng/g dry weight) were in the same range or lower than concentrations in dust from other European countries...
  77. doi request reprint Distribution of PCBs, their hydroxylated metabolites, and other phenolic contaminants in human serum from two European countries
    Alin C Dirtu
    Toxicological Center, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Sci Technol 44:2876-83. 2010
    ..The main chlorinated phenolic compound found in the Belgian samples was pentachlorophenol (PCP) which accounted for up to 85% of the total quantified phenolics, whereas in the Romanian samples, PCP accounted for only 35%...
  78. ncbi request reprint Enantiomeric signatures of chiral polychlorinated biphenyl atropisomers in livers of harbour porpoises (Phocoena phocoena) from the southern North Sea
    Shaogang Chu
    Toxicological Center, University of Antwerp, Universiteitsplain 1, 2610 Wilrijk, Belgium
    J Environ Monit 5:521-6. 2003
    ....
  79. pmc Distribution of methyl sulfone metabolites of polychlorinated biphenyls and p,p'-DDE in human tissues
    Shaogang Chu
    Toxicological Center, University of Antwerp, Wilrijk, Belgium
    Environ Health Perspect 111:1222-7. 2003
    ..Moreover, these profiles differ from those found in other mammals, such as polar bears, porpoises, and otters...
  80. ncbi request reprint The distribution of octachlorostyrene (OCS) in environmental samples from Europe
    Shaogang Chu
    Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    J Environ Monit 5:619-25. 2003
    ..38 ng/g ww) and liver (up to 0.05 ng/g ww), while it could not be detected in human brain or lung. The relationship between the concentrations of OCS and HCB was also discussed for each species...
  81. ncbi request reprint Dietary PBDE intake: a market-basket study in Belgium
    Stefan Voorspoels
    Toxicological Centre, Department of Pharmacy, University of Antwerp UA, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Int 33:93-7. 2007
    ..Although low contaminated, meat products account for around 30% of the total dietary intake of PBDEs. Dairy products and eggs contribute to a lesser degree (less than 30%)...
  82. ncbi request reprint Levels and chiral signatures of persistent organochlorine pollutants in human tissues from Belgium
    Shaogang Chu
    Toxicological Center, University of Antwerp, Universiteitsplein 1, Antwerpen Wilrijk 2610, Belgium
    Environ Res 93:167-76. 2003
    ..Higher enatiomeric ratios (ERs) for the three chiral PCBs were found in liver samples. The mean (range) ERs in liver were 1.69 (1.04-2.97), 1.16 (0.99-1.41), and 0.74 (0.48-0.97) for PCB 95, PCB 149, and PCB 132, respectively...
  83. ncbi request reprint Optimized separation and determination of methyl sulfone metabolites of polychlorinated biphenyls (PCBs) and p,p'-DDE in biota samples
    Shaogang Chu
    Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Analyst 127:1621-6. 2002
    ..33 ng g(-1)) ranged from 73 to 112% with a mean value of 89%. The coefficients of variation ranged from 5.2 to 12.2%, which is within the acceptable range for environmental analyses...
  84. doi request reprint Estimation of daily intake of organohalogenated contaminants from food consumption and indoor dust ingestion in Romania
    Alin C Dirtu
    Toxicological Center, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Sci Technol 44:6297-304. 2010
    ..The estimated intakes obtained in the present study are in good agreement with the higher concentrations of OCPs and the low levels of PBDEs reported recently in Romanian human samples...
  85. pmc Association of thyroid hormone concentrations with levels of organochlorine compounds in cord blood of neonates
    Johan Maervoet
    Toxicological Centre, University of Antwerp, Wilrijk, Belgium
    Environ Health Perspect 115:1780-6. 2007
    ..Whether these contaminants can affect circulating levels of thyroid hormones in humans is unclear, however, because the results of available studies are inconsistent...
  86. doi request reprint Concentrations in bird feathers reflect regional contamination with organic pollutants
    Veerle L B Jaspers
    Department of Biology, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Sci Total Environ 407:1447-51. 2009
    ..In summary, feathers seem to reflect regional variations in contamination, which strengthens their usefulness as a non-destructive biomonitor for organic pollutants...
  87. ncbi request reprint Highly chlorinated toxic contaminants in pesticide-treated wooden art objects
    Adrian Covaci
    Toxicological Centre, University of Antwerp, Wilrijk, Belgium
    Arch Environ Occup Health 61:245-8. 2006
    ..The presence of these toxic compounds in these antiques requires a better understanding of safety for the persons (conservators, museum employees, restorers, and visitors) coming in contact with these objects...
  88. ncbi request reprint Concentrations of synthetic musk compounds in personal care and sanitation products and human exposure profiles through dermal application
    Laurence Roosens
    Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, B 2610 Wilrijk, Belgium
    Chemosphere 69:1540-7. 2007
    ..In comparison, exposure to HHCB and AHTN increased up to 10 000 fold between low- and high-exposure...
  89. ncbi request reprint Distribution of organochlorine pesticides, polychlorinated biphenyls and alpha-HCH enantiomers in pork tissues
    Adrian Covaci
    Toxicological Center, University of Antwerp, Universiteitsplein 1, Wilrijk B 2610, Belgium
    Chemosphere 56:757-66. 2004
    ..Enantiomeric ratios in brain were the highest measured values between all organs. For all studied animals, ERs increased in the order fat < muscle < liver < brain...
  90. ncbi request reprint Accumulation of organochlorines and brominated flame retardants in the eggs and nestlings of great tits, Parus major
    Tom Dauwe
    Department of Biology and Toxicological Center, University of Antwerp, Universiteitsplein 1, B 2610 Antwerp, Belgium
    Environ Sci Technol 40:5297-303. 2006
    ..Nestling birds may therefore not be good sentinels for local contamination with persistent pollutants...
  91. ncbi request reprint Uptake and tissue-specific distribution of selected polychlorinated biphenyls in developing chicken embryos
    Johan Maervoet
    Toxicological Center, University of Antwerp, Universiteitsplein 1, B 2610 Wilrijk, Belgium
    Environ Toxicol Chem 24:597-602. 2005
    ..Lipid analysis of the organs suggested that the lipid composition of brain may be an important factor explaining the low PCB accumulation in this tissue...
  92. ncbi request reprint Optimization of the determination of polybrominated diphenyl ethers in human serum using solid-phase extraction and gas chromatography-electron capture negative ionization mass spectrometry
    Adrian Covaci
    Toxicological Center, University of Antwerp, Universiteitsplein 1, Building S, 6th Floor, 2610 Wilrijk, Belgium
    J Chromatogr B Analyt Technol Biomed Life Sci 827:216-23. 2005
    ..The method was applied to serum samples from a random Belgian population. The obtained results were within the range of PBDE levels in other non-exposed population from Europe...
  93. ncbi request reprint Hexabromocyclododecanes (HBCDs) in the environment and humans: a review
    Adrian Covaci
    Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Sci Technol 40:3679-88. 2006
    ..Whenever possible, HBCDs should be analyzed as individual stereoisomers in order to address their fate and effects...
  94. pmc A reassessment of the nomenclature of polychlorinated biphenyl (PCB) metabolites
    Johan Maervoet
    Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium
    Environ Health Perspect 112:291-4. 2004
    ....
  95. ncbi request reprint Determination of polybrominated diphenyl ethers and polychlorinated biphenyls in human adipose tissue by large-volume injection-narrow-bore capillary gas chromatography/electron impact low-resolution mass spectrometry
    Adrian Covaci
    Toxicological Center, University of Antwerp, Wilnijk, Belgium
    Anal Chem 74:790-8. 2002
    ..Levels of PBDEs in 20 Belgian human adipose tissue samples ranged between 2.18 and 11.70 ng/g lipid weight and were similar to previously reported values from Europe...