Inge Brouns

Summary

Affiliation: University of Antwerp
Country: Belgium

Publications

  1. ncbi request reprint Vesicular glutamate transporter 2 is expressed in different nerve fibre populations that selectively contact pulmonary neuroepithelial bodies
    Inge Brouns
    Laboratory of Cell Biology and Histology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Histochem Cell Biol 121:1-12. 2004
  2. ncbi request reprint Novel insights in the neurochemistry and function of pulmonary sensory receptors
    Inge Brouns
    University of Antwerp, Department of Veterinary Sciences, Laboratory of Cell Biology and Histology, Belgium
    Adv Anat Embryol Cell Biol 211:1-115, vii. 2012
  3. doi request reprint Neurochemical pattern of the complex innervation of neuroepithelial bodies in mouse lungs
    Inge Brouns
    Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Histochem Cell Biol 131:55-74. 2009
  4. doi request reprint Purinergic signaling in the pulmonary neuroepithelial body microenvironment unraveled by live cell imaging
    Ian De Proost
    Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium
    FASEB J 23:1153-60. 2009
  5. ncbi request reprint Sensory receptors in the airways: neurochemical coding of smooth muscle-associated airway receptors and pulmonary neuroepithelial body innervation
    Inge Brouns
    Laboratory of Cell Biology and Histology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Auton Neurosci 126:307-19. 2006
  6. ncbi request reprint Neurotrophin-4 dependency of intraepithelial vagal sensory nerve terminals that selectively contact pulmonary NEBs in mice
    Fusun Oztay
    Laboratory of Cell Biology and Histology, University of Antwerp, Antwerp, Belgium
    Histol Histopathol 25:975-84. 2010
  7. ncbi request reprint Neurochemical characterisation of sensory receptors in airway smooth muscle: comparison with pulmonary neuroepithelial bodies
    Inge Brouns
    Laboratory of Cell Biology and Histology, Department of Biomedical Sciences, University of Antwerp, Groenenborgerlaan 171, 2020, Antwerp, Belgium
    Histochem Cell Biol 125:351-67. 2006
  8. ncbi request reprint Selective visualisation of sensory receptors in the smooth muscle layer of ex-vivo airway whole-mounts by styryl pyridinium dyes
    Ian De Proost
    Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Groenenborgerlaan 171, BE 2020 Antwerp, Belgium
    Cell Tissue Res 329:421-31. 2007
  9. ncbi request reprint Evidence for a role of neuroepithelial bodies as complex airway sensors: comparison with smooth muscle-associated airway receptors
    Dirk Adriaensen
    Laboratory of Cell Biology and Histology, Dept of Veterinary Sciences, University of Antwerp, BE 2020 Antwerp, Belgium
    J Appl Physiol (1985) 101:960-70. 2006
  10. ncbi request reprint Functional expression of the multimodal extracellular calcium-sensing receptor in pulmonary neuroendocrine cells
    Robrecht Lembrechts
    Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, BE 2020 Antwerp, Belgium
    J Cell Sci 126:4490-501. 2013

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Vesicular glutamate transporter 2 is expressed in different nerve fibre populations that selectively contact pulmonary neuroepithelial bodies
    Inge Brouns
    Laboratory of Cell Biology and Histology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Histochem Cell Biol 121:1-12. 2004
    ....
  2. ncbi request reprint Novel insights in the neurochemistry and function of pulmonary sensory receptors
    Inge Brouns
    University of Antwerp, Department of Veterinary Sciences, Laboratory of Cell Biology and Histology, Belgium
    Adv Anat Embryol Cell Biol 211:1-115, vii. 2012
    ....
  3. doi request reprint Neurochemical pattern of the complex innervation of neuroepithelial bodies in mouse lungs
    Inge Brouns
    Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Histochem Cell Biol 131:55-74. 2009
    ..The neurochemical information on the innervation of NEBs in mouse lungs gathered in the present study will be essential for the interpretation of upcoming functional data and for the study of transgenic mice...
  4. doi request reprint Purinergic signaling in the pulmonary neuroepithelial body microenvironment unraveled by live cell imaging
    Ian De Proost
    Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium
    FASEB J 23:1153-60. 2009
    ....
  5. ncbi request reprint Sensory receptors in the airways: neurochemical coding of smooth muscle-associated airway receptors and pulmonary neuroepithelial body innervation
    Inge Brouns
    Laboratory of Cell Biology and Histology, University of Antwerp, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Auton Neurosci 126:307-19. 2006
    ..Electrophysiological data based on 'local' stimuli should be interpreted with caution, because of the regular close apposition of SMARs and NEBs and the very similar characteristics of their nerve terminals...
  6. ncbi request reprint Neurotrophin-4 dependency of intraepithelial vagal sensory nerve terminals that selectively contact pulmonary NEBs in mice
    Fusun Oztay
    Laboratory of Cell Biology and Histology, University of Antwerp, Antwerp, Belgium
    Histol Histopathol 25:975-84. 2010
    ..In view of the growing evidence for the involvement of NTs in neuronal plasticity associated with airway diseases, pulmonary NEBs innervated by NT-sensitive vagal afferents may play a significant role...
  7. ncbi request reprint Neurochemical characterisation of sensory receptors in airway smooth muscle: comparison with pulmonary neuroepithelial bodies
    Inge Brouns
    Laboratory of Cell Biology and Histology, Department of Biomedical Sciences, University of Antwerp, Groenenborgerlaan 171, 2020, Antwerp, Belgium
    Histochem Cell Biol 125:351-67. 2006
    ....
  8. ncbi request reprint Selective visualisation of sensory receptors in the smooth muscle layer of ex-vivo airway whole-mounts by styryl pyridinium dyes
    Ian De Proost
    Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Groenenborgerlaan 171, BE 2020 Antwerp, Belgium
    Cell Tissue Res 329:421-31. 2007
    ..As such, this model opens up further perspectives and creates a valid basis for direct physiological measurement and manipulation of the individually identified airway receptors...
  9. ncbi request reprint Evidence for a role of neuroepithelial bodies as complex airway sensors: comparison with smooth muscle-associated airway receptors
    Dirk Adriaensen
    Laboratory of Cell Biology and Histology, Dept of Veterinary Sciences, University of Antwerp, BE 2020 Antwerp, Belgium
    J Appl Physiol (1985) 101:960-70. 2006
    ..Future efforts should be directed toward finding out which airway receptor groups are selectively coupled to the complex NEB receptors...
  10. ncbi request reprint Functional expression of the multimodal extracellular calcium-sensing receptor in pulmonary neuroendocrine cells
    Robrecht Lembrechts
    Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, BE 2020 Antwerp, Belgium
    J Cell Sci 126:4490-501. 2013
    ..These data suggest that the NEB CaSR integrates multiple signals converging on this complex chemosensory unit, and is a key regulator of this intrapulmonary airway stem cell niche...
  11. doi request reprint Precision-cut vibratome slices allow functional live cell imaging of the pulmonary neuroepithelial body microenvironment in fetal mice
    Kathy Schnorbusch
    Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium
    Adv Exp Med Biol 758:157-66. 2012
    ....
  12. ncbi request reprint Quantification of neuroepithelial bodies and their innervation in fawn-hooded and Wistar rat lungs
    Jeroen Van Genechten
    Department of Biomedical Sciences, University of Antwerp RUCA, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    Am J Respir Cell Mol Biol 30:20-30. 2004
    ....
  13. ncbi request reprint Dual sensory innervation of pulmonary neuroepithelial bodies
    Inge Brouns
    Laboratory of Cell Biology and Histology, University of Antwerp RUCA, Antwerp, Belgium
    Am J Respir Cell Mol Biol 28:275-85. 2003
    ....
  14. ncbi request reprint Sensory receptors in the visceral pleura: neurochemical coding and live staining in whole mounts
    Isabel Pintelon
    Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Groenenborgerlaan 171, BE 2020 Antwerp, Belgium
    Am J Respir Cell Mol Biol 36:541-51. 2007
    ..The development of a live staining method, using AM1-43, showed that VPRs can be visualized in living tissue, offering an interesting model for future physiologic studies...
  15. ncbi request reprint Neuroepithelial bodies as mechanotransducers in the intrapulmonary airway epithelium: involvement of TRPC5
    Robrecht Lembrechts
    Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Groenenborgerlaan 171, BE 2020 Antwerp, Belgium
    Am J Respir Cell Mol Biol 47:315-23. 2012
    ....
  16. ncbi request reprint Reduced number of intrinsic pulmonary nitrergic neurons in Fawn-Hooded rats as compared to control rat strains
    Jeroen Van Genechten
    Laboratory of Cell Biology and Histology, Department of Biomedical Sciences, University of Antwerp RUCA, Antwerp, Belgium
    Anat Rec A Discov Mol Cell Evol Biol 272:446-53. 2003
    ..In conclusion, the possible links between neuronal NO, hypersensitivity to airway hypoxia, and the development of PPH clearly deserve further investigation...
  17. ncbi request reprint Pulmonary expression of voltage-gated calcium channels: special reference to sensory airway receptors
    Ian De Proost
    Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Groenenborgerlaan 171, BE 2020, Antwerp, Belgium
    Histochem Cell Biol 128:301-16. 2007
    ..Knowledge of the identification and localisation of Ca(v) channels in airway receptors and surrounding tissues provides a solid basis for interpretation of the calcium mediated activation studied in our ex vivo lung slice model...
  18. pmc Functional live cell imaging of the pulmonary neuroepithelial body microenvironment
    Ian De Proost
    Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium
    Am J Respir Cell Mol Biol 39:180-9. 2008
    ....
  19. ncbi request reprint Neuroepithelial bodies: a morphologic substrate for the link between neuronal nitric oxide and sensitivity to airway hypoxia?
    Inge Brouns
    Laboratory of Cell Biology and Histology, University of Antwerp RUCA, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    J Comp Neurol 449:343-54. 2002
    ....
  20. doi request reprint Expression of mechanogated two-pore domain potassium channels in mouse lungs: special reference to mechanosensory airway receptors
    Robrecht Lembrechts
    Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium
    Histochem Cell Biol 136:371-85. 2011
    ..TRAAK appears to be strongly involved in regulating airway mechanosensing since it was found to be expressed on the terminals of all subpopulations of potential vagal mechanosensors...
  21. doi request reprint GABAergic signaling in the pulmonary neuroepithelial body microenvironment: functional imaging in GAD67-GFP mice
    Kathy Schnorbusch
    Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Groenenborgerlaan 171, 2020, Antwerp, Belgium
    Histochem Cell Biol 140:549-66. 2013
    ..Different proof of concept experiments have clearly shown that adoption of the GAD67-GFP mouse model will certainly boost future functional imaging and gene expression analysis of the mouse NEB microenvironment. ..
  22. ncbi request reprint Functional morphology of pulmonary neuroepithelial bodies: extremely complex airway receptors
    Dirk Adriaensen
    Department of Biomedical Sciences, University of Antwerp RUCA, Antwerp, Belgium
    Anat Rec A Discov Mol Cell Evol Biol 270:25-40. 2003
    ....
  23. ncbi request reprint Neurochemical identification of enteric neurons expressing P2X(3) receptors in the guinea-pig ileum
    Luc Van Nassauw
    Laboratory of Cell Biology and Histology, University of Antwerp RUCA, Groenenborgerlaan 171, 2020 Antwerp, Belgium
    Histochem Cell Biol 118:193-203. 2002
    ..However, this does not negate the possibility that extrinsic sensory nerves expressing P2X(3) are involved in a purinergic mechanosensory transduction pathway as demonstrated in other organs...
  24. ncbi request reprint A globin in the nucleus!
    Eva Geuens
    Department of Biomedical Sciences, University of Antwerp, Universiteitsplein 1, B 2610 Antwerp, Belgium
    J Biol Chem 278:30417-20. 2003
    ..The immunoreactivity was restricted to the cytoplasm of neurons and endocrine beta cells. The nuclear localization of cytoglobin opens new perspectives for possible function(s) of globin-folded proteins as transcriptional regulators...
  25. ncbi request reprint Triple immunofluorescence staining with antibodies raised in the same species to study the complex innervation pattern of intrapulmonary chemoreceptors
    Inge Brouns
    Laboratory of Cell Biology and Histology, University of Antwerp RUCA, Groenenborgerlaan 171, B 2020 Antwerp, Belgium
    J Histochem Cytochem 50:575-82. 2002
    ....