Ph Beutels

Summary

Affiliation: University of Antwerp
Country: Belgium

Publications

  1. ncbi request reprint Economic evaluation of vaccination programmes: a consensus statement focusing on viral hepatitis
    Philippe Beutels
    Viral Hepatitis Prevention Board, Antwerp, Belgium
    Pharmacoeconomics 20:1-7. 2002
  2. pmc Cost effectiveness of pediatric pneumococcal conjugate vaccines: a comparative assessment of decision-making tools
    Nathorn Chaiyakunapruk
    Center of Pharmaceutical Outcomes Research, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand
    BMC Med 9:53. 2011
  3. pmc Estimating the impact of school closure on social mixing behaviour and the transmission of close contact infections in eight European countries
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Agoralaan 1, B3590 Diepenbeek, Belgium
    BMC Infect Dis 9:187. 2009
  4. pmc Mining social mixing patterns for infectious disease models based on a two-day population survey in Belgium
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics I BioStat, Hasselt University and Catholic University of Leuven, Agoralaan 1, 3590 Diepenbeek, Belgium
    BMC Infect Dis 9:5. 2009
  5. doi request reprint A brief history of economic evaluation for human papillomavirus vaccination policy
    Philippe Beutels
    Centre for Health Economics Research and Modeling Infectious Diseases, University of Antwerp, Antwerp 2610, Belgium
    Sex Health 7:352-8. 2010
  6. doi request reprint Funding of drugs: do vaccines warrant a different approach?
    Philippe Beutels
    Centre for Health Economics Research and Modelling Infectious Diseases, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
    Lancet Infect Dis 8:727-33. 2008
  7. doi request reprint Partially wrong? Partial equilibrium and the economic analysis of public health emergencies of international concern
    P Beutels
    Unit Health Economics and Modelling Infectious Diseases, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
    Health Econ 17:1317-22. 2008
  8. ncbi request reprint Convincing or confusing? Economic evaluations of childhood pneumococcal conjugate vaccination--a review (2002-2006)
    Philippe Beutels
    Centre for the Evaluation of Vaccination, Epidemiology and Social Medicine, University of Antwerp Campus Drie Eiken, Universiteitsplein 1, 2610 Antwerp, Belgium
    Vaccine 25:1355-67. 2007
  9. pmc Social mixing patterns for transmission models of close contact infections: exploring self-evaluation and diary-based data collection through a web-based interface
    P Beutels
    Centre for the Evaluation of Vaccination, Epidemiology and Social Medicine, University of Antwerp, Belgium
    Epidemiol Infect 134:1158-66. 2006
  10. ncbi request reprint Hepatitis B in St Petersburg, Russia (1994-1999): incidence, prevalence and force of infection
    Ph Beutels
    Centre for the Evaluation of Vaccination, WHO Collaborating Centre for the Prevention and Control of Viral Hepatitis, Epidemiology and Community Medicine, University of Antwerp, Antwerp, Belgium
    J Viral Hepat 10:141-9. 2003

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Economic evaluation of vaccination programmes: a consensus statement focusing on viral hepatitis
    Philippe Beutels
    Viral Hepatitis Prevention Board, Antwerp, Belgium
    Pharmacoeconomics 20:1-7. 2002
    ..While targeted hepatitis A vaccination seems economically unattractive, universal hepatitis A vaccination strategies have not yet been sufficiently investigated to draw general conclusions...
  2. pmc Cost effectiveness of pediatric pneumococcal conjugate vaccines: a comparative assessment of decision-making tools
    Nathorn Chaiyakunapruk
    Center of Pharmaceutical Outcomes Research, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand
    BMC Med 9:53. 2011
    ..With the aim to guide policymakers on their optimal use, we compared publicly available decision-making tools in relation to their methods, influential parameters and results...
  3. pmc Estimating the impact of school closure on social mixing behaviour and the transmission of close contact infections in eight European countries
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Agoralaan 1, B3590 Diepenbeek, Belgium
    BMC Infect Dis 9:187. 2009
    ..Of particular interest is the potential impact of school closure as a means of controlling pandemic influenza (and potentially other pathogens)...
  4. pmc Mining social mixing patterns for infectious disease models based on a two-day population survey in Belgium
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics I BioStat, Hasselt University and Catholic University of Leuven, Agoralaan 1, 3590 Diepenbeek, Belgium
    BMC Infect Dis 9:5. 2009
    ..In contrast to other European surveys conducted simultaneously, each respondent recorded contacts over two days. Special attention was given to holiday periods, and respondents with large numbers of professional contacts...
  5. doi request reprint A brief history of economic evaluation for human papillomavirus vaccination policy
    Philippe Beutels
    Centre for Health Economics Research and Modeling Infectious Diseases, University of Antwerp, Antwerp 2610, Belgium
    Sex Health 7:352-8. 2010
    ..This commentary discusses key issues for health economic evaluation and modelling, applied to human papillomavirus (HPV) vaccine programs...
  6. doi request reprint Funding of drugs: do vaccines warrant a different approach?
    Philippe Beutels
    Centre for Health Economics Research and Modelling Infectious Diseases, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
    Lancet Infect Dis 8:727-33. 2008
    ....
  7. doi request reprint Partially wrong? Partial equilibrium and the economic analysis of public health emergencies of international concern
    P Beutels
    Unit Health Economics and Modelling Infectious Diseases, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
    Health Econ 17:1317-22. 2008
    ..We propose an alternative, with the specific aim of accounting for the behavioural changes and capacity problems that are expected to occur when such an outbreak strikes...
  8. ncbi request reprint Convincing or confusing? Economic evaluations of childhood pneumococcal conjugate vaccination--a review (2002-2006)
    Philippe Beutels
    Centre for the Evaluation of Vaccination, Epidemiology and Social Medicine, University of Antwerp Campus Drie Eiken, Universiteitsplein 1, 2610 Antwerp, Belgium
    Vaccine 25:1355-67. 2007
    ....
  9. pmc Social mixing patterns for transmission models of close contact infections: exploring self-evaluation and diary-based data collection through a web-based interface
    P Beutels
    Centre for the Evaluation of Vaccination, Epidemiology and Social Medicine, University of Antwerp, Belgium
    Epidemiol Infect 134:1158-66. 2006
    ..125 for touching). We conclude that self-evaluation could yield similar results to diary surveys for general or very recent mixing information. More detailed data could be collected by diary, at little effort to respondents...
  10. ncbi request reprint Hepatitis B in St Petersburg, Russia (1994-1999): incidence, prevalence and force of infection
    Ph Beutels
    Centre for the Evaluation of Vaccination, WHO Collaborating Centre for the Prevention and Control of Viral Hepatitis, Epidemiology and Community Medicine, University of Antwerp, Antwerp, Belgium
    J Viral Hepat 10:141-9. 2003
    ..Without intervention, HB virus is expected to continue to spread rapidly with a greater proportion of female infections caused by sexual transmission. These trends may also provide an indication for HIV transmission...
  11. ncbi request reprint Immunogenicity, efficacy, safety and effectiveness of pneumococcal conjugate vaccines (1998-2006)
    Froukje Oosterhuis-Kafeja
    University of Antwerp, Antwerp, Belgium
    Vaccine 25:2194-212. 2007
    ..As more and more countries are using these vaccines routinely, post marketing surveillance studies will further establish the safety profile of PCVs...
  12. pmc Economic evaluation of options for measles vaccination strategy in a hypothetical Western European country
    Ph Beutels
    Centre for the Evaluation of Vaccination, Department of Epidemiology and Community Medicine, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
    Epidemiol Infect 130:273-83. 2003
    ....
  13. doi request reprint Cost-effectiveness of rotavirus vaccination: exploring caregiver(s) and "no medical care'' disease impact in Belgium
    Joke Bilcke
    Centre for Health Economics and Modelling Infectious Diseases, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Belgium
    Med Decis Making 29:33-50. 2009
    ..To estimate the cost-effectiveness of universal childhood rotavirus vaccination in Belgium, taking into account the impact of caregiver burden and the burden of sick children for whom no medical care is sought ("no medical care'' )...
  14. pmc Estimating the incidence of symptomatic rotavirus infections: a systematic review and meta-analysis
    Joke Bilcke
    Centre for Health Economics Research and Modeling of Infectious Diseases CHERMID, Vaccine and Infectious Disease Institute VAXINFECTIO, University of Antwerp, Wilrijk, Antwerp, Belgium
    PLoS ONE 4:e6060. 2009
    ....
  15. doi request reprint The health and economic burden of rotavirus disease in Belgium
    Joke Bilcke
    Unit for Health Economics and Modelling Infectious Diseases, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
    Eur J Pediatr 167:1409-19. 2008
    ..This burden is estimated to represent direct costs of 7.7 million Euro and indirect costs of 12.8 million Euro. Rotavirus disease causes a substantial health and economic burden in Belgium...
  16. doi request reprint Caregivers' willingness to pay to reduce the number of vaccine injections in infants
    Heidi Theeten
    Center for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
    Pediatr Infect Dis J 28:61-3. 2009
    ..These results suggest that more sophisticated methods are required, and similar analyses should exert a similar level of caution when presenting their results...
  17. ncbi request reprint Economic evaluations of varicella vaccination programmes: a review of the literature
    Nancy Thiry
    Department of Epidemiology and Social Medicine, Centre for the Evaluation of Vaccination, University of Antwerp, Antwerp, Belgium
    Pharmacoeconomics 21:13-38. 2003
    ..Since violation of these assumptions could have important adverse public health effects, we suggest pre-adolescent vaccination as a more secure alternative. This option deserves more attention in future analyses...
  18. doi request reprint Common attitudes about concomitant vaccine injections for infants and adolescents in Flanders, Belgium
    Heidi Theeten
    Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, B 2610 Antwerp, Belgium
    Vaccine 27:1964-9. 2009
    ..Work-loss due to vaccination was assessed for infants only and was rare (4.5%)...
  19. doi request reprint Reviewing the cost effectiveness of rotavirus vaccination: the importance of uncertainty in the choice of data sources
    Joke Bilcke
    Centre for Health Economics Research and Modelling of Infectious Diseases CHERMID, Centre for the Evaluation of Vaccination CEV, Vaccine and Infectious Disease Institute VAXINFECTIO, University of Antwerp, Antwerp, Belgium
    Pharmacoeconomics 27:281-97. 2009
    ..Furthermore, future analyses may have to consider ways of accounting for herd immunity (e.g. by using a dynamic model)...
  20. ncbi request reprint The seroepidemiology of primary varicella-zoster virus infection in Flanders (Belgium)
    Nancy Thiry
    Centre for the Evaluation of Vaccination, Department of Epidemiology and Community Medicine, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
    Eur J Pediatr 161:588-93. 2002
    ..The limited size of this second data set did not allow for an accurate assessment of the negative predictive value of such recollections...
  21. ncbi request reprint An economic evaluation of varicella vaccination in Italian adolescents
    Nancy Thiry
    Centre for the Evaluation of Vaccination, Epidemiology and Social Medicine, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
    Vaccine 22:3546-62. 2004
    ..For practical considerations, "anamnestic screening" seems to be the most convenient option...
  22. ncbi request reprint Economic aspects of pneumococcal pneumonia: a review of the literature
    Diana De Graeve
    Faculty of Applied Economics, University of Antwerp, Prinsstraat 13, 2000 Antwerp, Belgium
    Pharmacoeconomics 22:719-40. 2004
    ....
  23. doi request reprint Imputing QALYs from single time point health state descriptions on the EQ-5D and the SF-6D: a comparison of methods for hepatitis a patients
    Jeroen Luyten
    Centre for Health Economics Research and Modeling Infectious Diseases CHERMID, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
    Value Health 14:282-90. 2011
    ..In addition to more widely discussed issues such as the choice of instrument (e.g. EQ-5D or SF-6D?) researchers must also choose between different recall periods, scoring algorithms and interpolations between points of measurement...
  24. ncbi request reprint The difficult quest for data on "vanishing" vaccine-preventable infections in Europe: the case of measles in Flanders (Belgium)
    Ph Beutels
    Centre for the Evaluation of Vaccination, Epidemiology and Community Medicine, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium
    Vaccine 20:3551-9. 2002
    ..We noted throughout that many of the data sources are flawed. Better and accessible data bases are required to improve the reliability of similar studies in the future...
  25. doi request reprint Using empirical social contact data to model person to person infectious disease transmission: an illustration for varicella
    Benson Ogunjimi
    Centre for Health Economics Research and Modeling Infectious Diseases, Vaccine and Infectious Disease Institute, Faculty of Medicine, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, 2610 Antwerpen, Belgium
    Math Biosci 218:80-7. 2009
    ..Plausible values for R(0) for varicella in Belgium ranged from 7.66 to 13.44. Both approaches based on empirical social contact data provided a better fit to seroprevalence data than the current standard approach...
  26. doi request reprint Costing infectious disease outbreaks for economic evaluation: a review for hepatitis A
    Jeroen Luyten
    Centre for Health Economics Research and Modelling of Infectious Diseases CHERMID, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
    Pharmacoeconomics 27:379-89. 2009
    ..In order to do this, more studies documenting such outbreak-control strategies in terms of costs and resource use are needed...
  27. doi request reprint The economic impact of SARS in Beijing, China
    Philippe Beutels
    Centre for Health Economics Research and Modeling Infectious Diseases, Vaccine and Infectious Disease Institute, Faculty of Medicine, University of Antwerp, Belgium
    Trop Med Int Health 14:85-91. 2009
    ..To document the impact of the severe acute respiratory syndrome (SARS) outbreak in Beijing on indicators of social and economic activity...
  28. doi request reprint The effect of apoptotic cells on virus-specific immune responses detected using IFN-gamma ELISPOT
    Kevin Lenders
    Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute VAXINFECTIO, University of Antwerp, Antwerp University Hospital, Wilrijkstraat 10, B 2650 Edegem, Belgium
    J Immunol Methods 357:51-4. 2010
    ....
  29. ncbi request reprint Pharmacoeconomics of elderly vaccination against invasive pneumococcal infections: cost-effectiveness analyses and implications for The Netherlands
    Maarten J Postma
    Groningen University Institute for Drug Exploration University of Groningen Research Institute of Pharmacy GUIDE GRIP, Groningen, The Netherlands
    Expert Rev Vaccines 2:477-82. 2003
    ....
  30. ncbi request reprint Effectiveness of seven-valent pneumococcal conjugate vaccine
    Philippe Beutels
    Lancet 369:460; author reply 460. 2007
  31. ncbi request reprint Potential conflicts of interest in vaccine economics research: a commentary with a case study of pneumococcal conjugate vaccination
    Philippe Beutels
    The National Centre for Immunisation Research and Surveillance NCIRS, Royal Alexandra Hospital for Children, University of Sydney, Locked Bag 4001, Westmead, NSW 2145, Australia
    Vaccine 22:3312-22. 2004
    ..This paper explores the differences between them in relation to the four areas of bias. Finally, remedies to avoid bias in research and publications are proposed and discussed...
  32. pmc Precautionary behavior in response to perceived threat of pandemic influenza
    M Zia Sadique
    Statistics, Modelling and Bioinformatics Department, Health Protection Agency, London, United Kingdom
    Emerg Infect Dis 13:1307-13. 2007
    ..This international survey provides insight into what might be expected during an influenza pandemic...
  33. ncbi request reprint Methodological issues and new developments in the economic evaluation of vaccines
    Philippe Beutels
    National Center for Immunisation Research and Surveillance, University of Sydney and Center for Health Economics Research and Evaluation, Australia
    Expert Rev Vaccines 2:649-60. 2003
    ..Developments in the next 5 years are likely to address all of these issues and result in more sophisticated and accurate models of vaccination programs...
  34. ncbi request reprint Cost-effectiveness analyses of human papillomavirus vaccination
    Anthony T Newall
    School of Public Health, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia
    Lancet Infect Dis 7:289-96. 2007
    ..Further refinements to model design and epidemiological variables of (type-specific) HPV disease progression, and expansions on the options for vaccine use, are required for policy making...
  35. ncbi request reprint The role of economic evaluation in vaccine decision making: focus on meningococcal group C conjugate vaccine
    Robert Welte
    Institute of Health Economics and Health Care Management, GSF National Research Center for Environment and Health, Neuherberg, Germany
    Pharmacoeconomics 23:855-74. 2005
    ..In order to improve the international comparability of such studies, firmer national and international modelling guidelines and better adherence to such guidelines seem necessary...
  36. ncbi request reprint Valuing prevention through economic evaluation: some considerations regarding the choice of discount model for health effects with focus on infectious diseases
    Jasper M Bos
    Groningen University Institute for Drug Exploration, University of Groningen, Groningen, The Netherlands
    Pharmacoeconomics 22:1171-9. 2004
    ..A numerical example illustrates our approach. We discuss the associated potential implications for public health policy and discuss how the effects of the intervention can be additionally corrected for societal preferences...
  37. ncbi request reprint Comments on the Prosser et Al approach to value disease reduction in children
    Philippe Beutels
    Pediatrics 114:1375; author reply 1375-6. 2004
  38. ncbi request reprint The cost-effectiveness of rotavirus vaccination in Australia
    Anthony T Newall
    School of Public Health, The University of Sydney, The Children s Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia
    Vaccine 25:8851-60. 2007
    ....