Research Topics
| Ph BeutelsSummaryAffiliation: University of Antwerp Country: Belgium Publications
| Collaborators
|
Detail Information
Publications
Economic evaluation of vaccination programmes: a consensus statement focusing on viral hepatitisPhilippe Beutels
Viral Hepatitis Prevention Board, Antwerp, Belgium
Pharmacoeconomics 20:1-7. 2002..While targeted hepatitis A vaccination seems economically unattractive, universal hepatitis A vaccination strategies have not yet been sufficiently investigated to draw general conclusions...
Cost effectiveness of pediatric pneumococcal conjugate vaccines: a comparative assessment of decision-making toolsNathorn Chaiyakunapruk
Center of Pharmaceutical Outcomes Research, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand
BMC Med 9:53. 2011..With the aim to guide policymakers on their optimal use, we compared publicly available decision-making tools in relation to their methods, influential parameters and results...- Estimating the impact of school closure on social mixing behaviour and the transmission of close contact infections in eight European countriesNiel Hens
Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Agoralaan 1, B3590 Diepenbeek, Belgium
BMC Infect Dis 9:187. 2009..Of particular interest is the potential impact of school closure as a means of controlling pandemic influenza (and potentially other pathogens)... - Mining social mixing patterns for infectious disease models based on a two-day population survey in BelgiumNiel Hens
Interuniversity Institute for Biostatistics and Statistical Bioinformatics I BioStat, Hasselt University and Catholic University of Leuven, Agoralaan 1, 3590 Diepenbeek, Belgium
BMC Infect Dis 9:5. 2009..In contrast to other European surveys conducted simultaneously, each respondent recorded contacts over two days. Special attention was given to holiday periods, and respondents with large numbers of professional contacts... 
A brief history of economic evaluation for human papillomavirus vaccination policyPhilippe Beutels
Centre for Health Economics Research and Modeling Infectious Diseases, University of Antwerp, Antwerp 2610, Belgium
Sex Health 7:352-8. 2010..This commentary discusses key issues for health economic evaluation and modelling, applied to human papillomavirus (HPV) vaccine programs...- Funding of drugs: do vaccines warrant a different approach?Philippe Beutels
Centre for Health Economics Research and Modelling Infectious Diseases, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
Lancet Infect Dis 8:727-33. 2008.... - Partially wrong? Partial equilibrium and the economic analysis of public health emergencies of international concernP Beutels
Unit Health Economics and Modelling Infectious Diseases, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
Health Econ 17:1317-22. 2008..We propose an alternative, with the specific aim of accounting for the behavioural changes and capacity problems that are expected to occur when such an outbreak strikes... - Convincing or confusing? Economic evaluations of childhood pneumococcal conjugate vaccination--a review (2002-2006)Philippe Beutels
Centre for the Evaluation of Vaccination, Epidemiology and Social Medicine, University of Antwerp Campus Drie Eiken, Universiteitsplein 1, 2610 Antwerp, Belgium
Vaccine 25:1355-67. 2007.... - Social mixing patterns for transmission models of close contact infections: exploring self-evaluation and diary-based data collection through a web-based interfaceP Beutels
Centre for the Evaluation of Vaccination, Epidemiology and Social Medicine, University of Antwerp, Belgium
Epidemiol Infect 134:1158-66. 2006..125 for touching). We conclude that self-evaluation could yield similar results to diary surveys for general or very recent mixing information. More detailed data could be collected by diary, at little effort to respondents... - Hepatitis B in St Petersburg, Russia (1994-1999): incidence, prevalence and force of infectionPh Beutels
Centre for the Evaluation of Vaccination, WHO Collaborating Centre for the Prevention and Control of Viral Hepatitis, Epidemiology and Community Medicine, University of Antwerp, Antwerp, Belgium
J Viral Hepat 10:141-9. 2003..Without intervention, HB virus is expected to continue to spread rapidly with a greater proportion of female infections caused by sexual transmission. These trends may also provide an indication for HIV transmission... - Immunogenicity, efficacy, safety and effectiveness of pneumococcal conjugate vaccines (1998-2006)Froukje Oosterhuis Kafeja
University of Antwerp, Antwerp, Belgium
Vaccine 25:2194-212. 2007..As more and more countries are using these vaccines routinely, post marketing surveillance studies will further establish the safety profile of PCVs... - Economic evaluation of options for measles vaccination strategy in a hypothetical Western European countryPh Beutels
Centre for the Evaluation of Vaccination, Department of Epidemiology and Community Medicine, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
Epidemiol Infect 130:273-83. 2003.... - Cost-effectiveness of rotavirus vaccination: exploring caregiver(s) and "no medical care'' disease impact in BelgiumJoke Bilcke
Centre for Health Economics and Modelling Infectious Diseases, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Belgium
Med Decis Making 29:33-50. 2009..To estimate the cost-effectiveness of universal childhood rotavirus vaccination in Belgium, taking into account the impact of caregiver burden and the burden of sick children for whom no medical care is sought ("no medical care'' )... - Estimating the incidence of symptomatic rotavirus infections: a systematic review and meta-analysisJoke Bilcke
Centre for Health Economics Research and Modeling of Infectious Diseases CHERMID, Vaccine and Infectious Disease Institute VAXINFECTIO, University of Antwerp, Wilrijk, Antwerp, Belgium
PLoS ONE 4:e6060. 2009.... - The health and economic burden of rotavirus disease in BelgiumJoke Bilcke
Unit for Health Economics and Modelling Infectious Diseases, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
Eur J Pediatr 167:1409-19. 2008..This burden is estimated to represent direct costs of 7.7 million Euro and indirect costs of 12.8 million Euro. Rotavirus disease causes a substantial health and economic burden in Belgium... - Caregivers' willingness to pay to reduce the number of vaccine injections in infantsHeidi Theeten
Center for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
Pediatr Infect Dis J 28:61-3. 2009..These results suggest that more sophisticated methods are required, and similar analyses should exert a similar level of caution when presenting their results... - Economic evaluations of varicella vaccination programmes: a review of the literatureNancy Thiry
Department of Epidemiology and Social Medicine, Centre for the Evaluation of Vaccination, University of Antwerp, Antwerp, Belgium
Pharmacoeconomics 21:13-38. 2003..Since violation of these assumptions could have important adverse public health effects, we suggest pre-adolescent vaccination as a more secure alternative. This option deserves more attention in future analyses... - Common attitudes about concomitant vaccine injections for infants and adolescents in Flanders, BelgiumHeidi Theeten
Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, B 2610 Antwerp, Belgium
Vaccine 27:1964-9. 2009..Work-loss due to vaccination was assessed for infants only and was rare (4.5%)... - Reviewing the cost effectiveness of rotavirus vaccination: the importance of uncertainty in the choice of data sourcesJoke Bilcke
Centre for Health Economics Research and Modelling of Infectious Diseases CHERMID, Centre for the Evaluation of Vaccination CEV, Vaccine and Infectious Disease Institute VAXINFECTIO, University of Antwerp, Antwerp, Belgium
Pharmacoeconomics 27:281-97. 2009..Furthermore, future analyses may have to consider ways of accounting for herd immunity (e.g. by using a dynamic model)... - The seroepidemiology of primary varicella-zoster virus infection in Flanders (Belgium)Nancy Thiry
Centre for the Evaluation of Vaccination, Department of Epidemiology and Community Medicine, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
Eur J Pediatr 161:588-93. 2002..Adolescent strategies can minimise the population risks involved but the accuracy of non positive antecedents of chickenpox needs to be documented to assess the efficiency of such strategies... - An economic evaluation of varicella vaccination in Italian adolescentsNancy Thiry
Centre for the Evaluation of Vaccination, Epidemiology and Social Medicine, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
Vaccine 22:3546-62. 2004..For practical considerations, "anamnestic screening" seems to be the most convenient option... - Economic aspects of pneumococcal pneumonia: a review of the literatureDiana De Graeve
Faculty of Applied Economics, University of Antwerp, Prinsstraat 13, 2000 Antwerp, Belgium
Pharmacoeconomics 22:719-40. 2004.... - Imputing QALYs from single time point health state descriptions on the EQ-5D and the SF-6D: a comparison of methods for hepatitis a patientsJeroen Luyten
Centre for Health Economics Research and Modeling Infectious Diseases CHERMID, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
Value Health 14:282-90. 2011..In addition to more widely discussed issues such as the choice of instrument (e.g. EQ-5D or SF-6D?) researchers must also choose between different recall periods, scoring algorithms and interpolations between points of measurement... - The difficult quest for data on "vanishing" vaccine-preventable infections in Europe: the case of measles in Flanders (Belgium)Ph Beutels
Centre for the Evaluation of Vaccination, Epidemiology and Community Medicine, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium
Vaccine 20:3551-9. 2002..We noted throughout that many of the data sources are flawed. Better and accessible data bases are required to improve the reliability of similar studies in the future... - Using empirical social contact data to model person to person infectious disease transmission: an illustration for varicellaBenson Ogunjimi
Centre for Health Economics Research and Modeling Infectious Diseases, Vaccine and Infectious Disease Institute, Faculty of Medicine, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, 2610 Antwerpen, Belgium
Math Biosci 218:80-7. 2009..Plausible values for R(0) for varicella in Belgium ranged from 7.66 to 13.44. Both approaches based on empirical social contact data provided a better fit to seroprevalence data than the current standard approach... - Costing infectious disease outbreaks for economic evaluation: a review for hepatitis AJeroen Luyten
Centre for Health Economics Research and Modelling of Infectious Diseases CHERMID, Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium
Pharmacoeconomics 27:379-89. 2009..In order to do this, more studies documenting such outbreak-control strategies in terms of costs and resource use are needed... - The economic impact of SARS in Beijing, ChinaPhilippe Beutels
Centre for Health Economics Research and Modeling Infectious Diseases, Vaccine and Infectious Disease Institute, Faculty of Medicine, University of Antwerp, Belgium
Trop Med Int Health 14:85-91. 2009..To document the impact of the severe acute respiratory syndrome (SARS) outbreak in Beijing on indicators of social and economic activity... - The effect of apoptotic cells on virus-specific immune responses detected using IFN-gamma ELISPOTKevin Lenders
Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute VAXINFECTIO, University of Antwerp, Antwerp University Hospital, Wilrijkstraat 10, B 2650 Edegem, Belgium
J Immunol Methods 357:51-4. 2010.... - Pharmacoeconomics of elderly vaccination against invasive pneumococcal infections: cost-effectiveness analyses and implications for The NetherlandsMaarten J Postma
Groningen University Institute for Drug Exploration University of Groningen Research Institute of Pharmacy GUIDE GRIP, Groningen, The Netherlands
Expert Rev Vaccines 2:477-82. 2003.... - Effectiveness of seven-valent pneumococcal conjugate vaccinePhilippe Beutels
Lancet 369:460; author reply 460. 2007 - Potential conflicts of interest in vaccine economics research: a commentary with a case study of pneumococcal conjugate vaccinationPhilippe Beutels
The National Centre for Immunisation Research and Surveillance NCIRS, Royal Alexandra Hospital for Children, University of Sydney, Locked Bag 4001, Westmead, NSW 2145, Australia
Vaccine 22:3312-22. 2004..This paper explores the differences between them in relation to the four areas of bias. Finally, remedies to avoid bias in research and publications are proposed and discussed... - Precautionary behavior in response to perceived threat of pandemic influenzaM Zia Sadique
Statistics, Modelling and Bioinformatics Department, Health Protection Agency, London, United Kingdom
Emerg Infect Dis 13:1307-13. 2007..This international survey provides insight into what might be expected during an influenza pandemic... - Methodological issues and new developments in the economic evaluation of vaccinesPhilippe Beutels
National Center for Immunisation Research and Surveillance, University of Sydney and Center for Health Economics Research and Evaluation, Australia
Expert Rev Vaccines 2:649-60. 2003..Developments in the next 5 years are likely to address all of these issues and result in more sophisticated and accurate models of vaccination programs... - Cost-effectiveness analyses of human papillomavirus vaccinationAnthony T Newall
School of Public Health, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia
Lancet Infect Dis 7:289-96. 2007..Further refinements to model design and epidemiological variables of (type-specific) HPV disease progression, and expansions on the options for vaccine use, are required for policy making... - The role of economic evaluation in vaccine decision making: focus on meningococcal group C conjugate vaccineRobert Welte
Institute of Health Economics and Health Care Management, GSF National Research Center for Environment and Health, Neuherberg, Germany
Pharmacoeconomics 23:855-74. 2005..In order to improve the international comparability of such studies, firmer national and international modelling guidelines and better adherence to such guidelines seem necessary... - Valuing prevention through economic evaluation: some considerations regarding the choice of discount model for health effects with focus on infectious diseasesJasper M Bos
Groningen University Institute for Drug Exploration, University of Groningen, Groningen, The Netherlands
Pharmacoeconomics 22:1171-9. 2004..A numerical example illustrates our approach. We discuss the associated potential implications for public health policy and discuss how the effects of the intervention can be additionally corrected for societal preferences... - Comments on the Prosser et Al approach to value disease reduction in childrenPhilippe Beutels
Pediatrics 114:1375; author reply 1375-6. 2004 - The cost-effectiveness of rotavirus vaccination in AustraliaAnthony T Newall
School of Public Health, The University of Sydney, The Children s Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia
Vaccine 25:8851-60. 2007....