Research Topics
| Maarten AlbersenSummaryAffiliation: University Hospitals Leuven Country: Belgium Publications
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Detail Information
Publications
Evaluation and treatment of erectile dysfunction in the aging male: a mini-reviewMaarten Albersen
Department of Urology, University of California at San Francisco, San Francisco, CA, USA
Gerontology 58:3-14. 2012..This mini-review provides an overview of contemporary literature concerning epidemiology, pathophysiology, assessment and treatment of erectile dysfunction in the aging male...
Functional, metabolic, and morphologic characteristics of a novel rat model of type 2 diabetes-associated erectile dysfunctionMaarten Albersen
Knuppe Molecular Urology Laboratory, Department of Urology, University of California, San Francisco, CA, USA
Urology 78:476.e1-8. 2011..To conduct a pilot study to investigate functional, metabolic, and penile morphologic changes in a novel model of lean DM2. Erectile dysfunction (ED) is a frequent sequela in patients with type 2 diabetes mellitus (DM2)...
Recruitment of intracavernously injected adipose-derived stem cells to the major pelvic ganglion improves erectile function in a rat model of cavernous nerve injuryThomas M Fandel
Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA, USA
Eur Urol 61:201-10. 2012..Intracavernous (IC) injection of stem cells has been shown to ameliorate cavernous-nerve (CN) injury-induced erectile dysfunction (ED). However, the mechanisms of action of adipose-derived stem cells (ADSC) remain unclear...
Effects of prolonged vaginal distension and β-aminopropionitrile on urinary continence and urethral structureGuifang Wang
Department of Urology, University of California, School of Medicine, San Francisco, CA, USA
Urology 78:968.e13-9. 2011..To investigate the effects of prolonged vaginal distension and β-aminopropionitrile (BAPN) on the urinary patterns and urethral structure in female virgin rats...
Effects of intravenous injection of adipose-derived stem cells in a rat model of radiation therapy-induced erectile dysfunctionXuefeng Qiu
Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA 94143 0738, USA
J Sex Med 9:1834-41. 2012..Radiation therapy (RT) for prostate cancer is frequently associated with posttreatment erectile dysfunction (ED)...
Both immediate and delayed intracavernous injection of autologous adipose-derived stromal vascular fraction enhances recovery of erectile function in a rat model of cavernous nerve injuryXuefeng Qiu
Knuppe Molecular Urology Laboratory, Department of Urology, University of California, San Francisco, CA 94143 0738, USA
Eur Urol 62:720-7. 2012..However, culturing exposes ADSCs to the risk of contamination and dedifferentiation...
Pentoxifylline promotes recovery of erectile function in a rat model of postprostatectomy erectile dysfunctionMaarten Albersen
Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA 94143 0738, USA
Eur Urol 59:286-96. 2011..Pentoxifylline (PTX) is a phosphodiesterase inhibitor that further inhibits multiple cytokine pathways involved in nerve degeneration, apoptosis, and fibrosis...
Cavernous nerve repair with allogenic adipose matrix and autologous adipose-derived stem cellsGuiting Lin
Knuppe Molecular Urology Laboratory, Department of Urology, University of California, San Francisco, CA 94143 0738, USA
Urology 77:1509.e1-8. 2011..To investigate whether adipose-derived matrix seeded with adipose-derived stem cells (ADSC) can facilitate the repair of injured cavernous nerves (CNs)...
Improved penile histology by phalloidin stain: circular and longitudinal cavernous smooth muscles, dual-endothelium arteries, and erectile dysfunction-associated changesGuiting Lin
Department of Urology, University of California, San Francisco, CA, USA
Urology 78:970.e1-8. 2011..To investigate whether fluorochrome-conjugated phalloidin can delineate cavernous smooth muscle (CSM) cells and whether it can be combined with immunofluorescence (IF) staining to quantify erectile dysfunction (ED)-associated changes...
Effects of EdU labeling on mesenchymal stem cellsHongxiu Ning
Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA 94143, USA
Cytotherapy 15:57-63. 2013..In the present study, we tested whether EdU was cytotoxic and whether it interfered with differentiation, cytokine secretion and migration of MSCs...
Injections of adipose tissue-derived stem cells and stem cell lysate improve recovery of erectile function in a rat model of cavernous nerve injuryMaarten Albersen
Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA 94143 0738, USA
J Sex Med 7:3331-40. 2010..However, the mechanisms of action for stem cell therapy remain controversial, with increasing evidence pointing to paracrine pathways...
Stem cells: novel players in the treatment of erectile dysfunctionHaiyang Zhang
Minimally Invasive Urology Center, Provincial Hospital affiliated to Shandong University, Jinan, China
Asian J Androl 14:145-55. 2012..In addition, several subtypes of ASCs are localized in the penis, and circulating endogenous stem cells can be employed to predict the outcome of ED and ED-related cardiovascular diseases...
The future is today: emerging drugs for the treatment of erectile dysfunctionMaarten Albersen
Basic Research Fellow Male Sexual Dysfunction, University of California at San Francisco, Department of Urology, Knuppe Molecular Urology Laboratory, Campus Box 0738, San Francisco, CA 94143 0738, USA
Expert Opin Emerg Drugs 15:467-80. 2010..PDE type 5 inhibitors (PDE5I) now account for the largest segment of the ED market. While these drugs are highly efficacious for many men, a relatively large subset of ED patients who do not respond to PDE5I is increasingly recognized...
Multipotent stromal cell therapy for cavernous nerve injury-induced erectile dysfunctionMaarten Albersen
Laboratory of Experimental Urology, University Hospitals Leuven, Leuven, Belgium
J Sex Med 9:385-403. 2012..Multipotent stromal cells (MSCs) are an attractive cell source for this application based on their regenerative potential and their clinical applicability...
