Jean Pierre Hachem

Summary

Affiliation: Universitair Ziekenhuis Brussel
Country: Belgium

Publications

  1. ncbi Effect of rice starch as a bath additive on the barrier function of healthy but SLS-damaged skin and skin of atopic patients
    Kristien De Paepe
    Department of Toxicology, Vrije Universiteit Brussel, Brussels, Belgium
    Acta Derm Venereol 82:184-6. 2002
  2. pmc Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes
    Jean Pierre Hachem
    Department of Dermatology, Universitair Ziekenhuis Brussel Vrije Universiteit Brussel, Brussels, Belgium
    J Invest Dermatol 130:500-10. 2010
  3. doi Cannabinoid receptors 1 and 2 oppositely regulate epidermal permeability barrier status and differentiation
    Truus Roelandt
    Department of Dermatology, Vrije Universiteit Brussel, Brussels, Belgium
    Exp Dermatol 21:688-93. 2012
  4. doi Actin dynamics regulate immediate PAR-2-dependent responses to acute epidermal permeability barrier abrogation
    Truus Roelandt
    Department of Dermatology, Universitair Ziekenhuis Brussel, Brussels, Belgium
    J Dermatol Sci 61:101-9. 2011
  5. ncbi Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome
    Jean Pierre Hachem
    Dienst Dermatologie, Academisch Ziekenhuis Vrije Universiteit Brussel, Brussels, Belgium
    J Invest Dermatol 126:1609-21. 2006
  6. doi The "caveolae brake hypothesis" and the epidermal barrier
    Truus Roelandt
    Department of Dermatology, Free University of Brussels, Brussels, Belgium
    J Invest Dermatol 129:927-36. 2009
  7. doi Proteolytically active allergens cause barrier breakdown
    Truus Roelandt
    Dienst Dermatologie, Universitair Ziekenhuis Vrije Universiteit Brussel, Brussels, Belgium
    J Invest Dermatol 128:1878-80. 2008
  8. ncbi Evaluation of biophysical and clinical parameters of skin barrier function among hospital workers
    Jean Pierre Hachem
    Department of Dermatology, Vrije Universiteit Brussel, B 1090 Brussels, Belgium
    Contact Dermatitis 46:220-3. 2002

Collaborators

Detail Information

Publications8

  1. ncbi Effect of rice starch as a bath additive on the barrier function of healthy but SLS-damaged skin and skin of atopic patients
    Kristien De Paepe
    Department of Toxicology, Vrije Universiteit Brussel, Brussels, Belgium
    Acta Derm Venereol 82:184-6. 2002
    ..Rice starch in powder or formulated in a bath product can therefore be recommended as a skin repair bathing additive for barrier damaged skin, particularly in the case of atopic dermatitis patients...
  2. pmc Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes
    Jean Pierre Hachem
    Department of Dermatology, Universitair Ziekenhuis Brussel Vrije Universiteit Brussel, Brussels, Belgium
    J Invest Dermatol 130:500-10. 2010
    ....
  3. doi Cannabinoid receptors 1 and 2 oppositely regulate epidermal permeability barrier status and differentiation
    Truus Roelandt
    Department of Dermatology, Vrije Universiteit Brussel, Brussels, Belgium
    Exp Dermatol 21:688-93. 2012
    ..Altogether, these observations put forward the importance and the complexity of cannabinoid signalling for the regulation of permeability barrier and epidermal differentiation...
  4. doi Actin dynamics regulate immediate PAR-2-dependent responses to acute epidermal permeability barrier abrogation
    Truus Roelandt
    Department of Dermatology, Universitair Ziekenhuis Brussel, Brussels, Belgium
    J Dermatol Sci 61:101-9. 2011
    ..Lamellar body (LB) secretion and terminal differentiation of stratum granulosum (SG) cells are signaled by both protease activated receptor-2 (PAR-2) and caveolin-1 (cav-1)...
  5. ncbi Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome
    Jean Pierre Hachem
    Dienst Dermatologie, Academisch Ziekenhuis Vrije Universiteit Brussel, Brussels, Belgium
    J Invest Dermatol 126:1609-21. 2006
    ..These studies provide a mechanistic basis for phenotypic variations in NS, and describe compensatory mechanisms that permit survival of NS patients in the face of unrelenting SP attack...
  6. doi The "caveolae brake hypothesis" and the epidermal barrier
    Truus Roelandt
    Department of Dermatology, Free University of Brussels, Brussels, Belgium
    J Invest Dermatol 129:927-36. 2009
    ..These studies demonstrate that cav-1 delivery to the APM by LB trafficking to APM "brakes" further LB secretion, signals terminal differentiation, and regulates epidermal hyperproliferation...
  7. doi Proteolytically active allergens cause barrier breakdown
    Truus Roelandt
    Dienst Dermatologie, Universitair Ziekenhuis Vrije Universiteit Brussel, Brussels, Belgium
    J Invest Dermatol 128:1878-80. 2008
    ..This article exposes the secretive boundaries between barrier homeostasis and immunity...
  8. ncbi Evaluation of biophysical and clinical parameters of skin barrier function among hospital workers
    Jean Pierre Hachem
    Department of Dermatology, Vrije Universiteit Brussel, B 1090 Brussels, Belgium
    Contact Dermatitis 46:220-3. 2002
    ..The results suggest the presence of skin barrier alterations and clinical signs of chronic ICD on the hands of nurses working in operating room units...