Pierre R Smeesters

Summary

Country: Belgium

Publications

  1. ncbi Pharyngitis in low-resources settings: a pragmatic clinical approach to reduce unnecessary antibiotic use
    Pierre Robert Smeesters
    Servico de Pediatria, Hospital Universitario de Brasilia, Universidade de Brasilia, Brasilia, Brazil
    Pediatrics 118:e1607-11. 2006
  2. ncbi Science that "knows" and science that "asks"
    Pierre R Smeesters
    Laboratory of Bacterial Genetics and Physiology, IBMM, Faculte des Sciences, Universite Libre de Bruxelles, Belgium
    J Transl Med 9:128. 2011
  3. ncbi Polyclonal dissemination of tetracycline resistance among Streptococcus pyogenes paediatric isolates from Brazil
    Pierre Robert Smeesters
    Institut de Biologie et de Médecine Moléculaires, Faculte des Sciences, Universite Libre de Bruxelles, Belgium
    J Infect Dev Ctries 4:704-11. 2010
  4. ncbi The streptococcal M protein: a highly versatile molecule
    Pierre R Smeesters
    Bacterial Pathogenesis Laboratory, Queensland Institute of Medical Research, Brisbane 4029, Queensland, Australia
    Trends Microbiol 18:275-82. 2010
  5. ncbi Differences among group A streptococcus epidemiological landscapes: consequences for M protein-based vaccines?
    Pierre R Smeesters
    Bacterial Pathogenesis Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland 4029, Australia
    Expert Rev Vaccines 8:1705-20. 2009
  6. ncbi Group A Streptococcus virulence and host factors in two toddlers with rheumatic fever following toxic shock syndrome
    Pierre Robert Smeesters
    Laboratoire de Génétique et Physiologie Bactérienne, Institut de Biologie et de Médecine Moléculaires, Faculte des Sciences, Universite Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, B6041 Gosselies, Belgium
    Int J Infect Dis 14:e403-9. 2010
  7. ncbi Emerging fluoroquinolone-non-susceptible group A streptococci in two different paediatric populations
    Pierre Robert Smeesters
    Laboratoire de Génétique et Physiologie Bactérienne, Institut de Biologie et de Médecine Moléculaires IBMM, Faculte des Sciences, Universite Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, 6041 Gosselies, Belgium
    Int J Antimicrob Agents 34:44-9. 2009
  8. ncbi Genetic diversity of Group A Streptococcus M protein: implications for typing and vaccine development
    Pierre R Smeesters
    Laboratoire de Génétique et Physiologie Bactérienne, Institut de Biologie et de Médecine Moléculaires, Faculte des Sciences, Universite Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, 6041 Gosselies, Belgium
    Vaccine 26:5835-42. 2008
  9. ncbi Differences between Belgian and Brazilian group A Streptococcus epidemiologic landscape
    Pierre Robert Smeesters
    Infectious Diseases Department, Hopital Universitaire des Enfants Reine Fabiola, Universite Libre de Bruxelles, Brussels, Belgium Laboratoire de Génétique des Procaryotes, Institut de Biologie et de Médecine Moléculaires, Universite Libre de Bruxelles, Brussels, Belgium Pediatric Department, Hospital Universitario de Brasilia, Universidade de Brasilia, Brasilia, Brazil
    PLoS ONE 1:e10. 2006
  10. ncbi Characterization of novel phages isolated in coagulase-negative staphylococci reveals evolutionary relationships with Staphylococcus aureus phages
    Marie Deghorain
    Laboratoire de Génétique et Physiologie Bactérienne, Faculte de Sciences, IBMM, Universite Libre de Bruxelles, Gosselies, Belgium
    J Bacteriol 194:5829-39. 2012

Collaborators

Detail Information

Publications16

  1. ncbi Pharyngitis in low-resources settings: a pragmatic clinical approach to reduce unnecessary antibiotic use
    Pierre Robert Smeesters
    Servico de Pediatria, Hospital Universitario de Brasilia, Universidade de Brasilia, Brasilia, Brazil
    Pediatrics 118:e1607-11. 2006
    ....
  2. ncbi Science that "knows" and science that "asks"
    Pierre R Smeesters
    Laboratory of Bacterial Genetics and Physiology, IBMM, Faculte des Sciences, Universite Libre de Bruxelles, Belgium
    J Transl Med 9:128. 2011
    ..A stereotypic representation of both these worlds is presented as a starting point to encourage debate on this issue...
  3. ncbi Polyclonal dissemination of tetracycline resistance among Streptococcus pyogenes paediatric isolates from Brazil
    Pierre Robert Smeesters
    Institut de Biologie et de Médecine Moléculaires, Faculte des Sciences, Universite Libre de Bruxelles, Belgium
    J Infect Dev Ctries 4:704-11. 2010
    ..Scarce data are available on Group A Streptococcus (GAS) antibiotic resistance in South America...
  4. ncbi The streptococcal M protein: a highly versatile molecule
    Pierre R Smeesters
    Bacterial Pathogenesis Laboratory, Queensland Institute of Medical Research, Brisbane 4029, Queensland, Australia
    Trends Microbiol 18:275-82. 2010
    ..This review focuses on the known interactions between M proteins and host ligand proteins, emphasizing that our understanding of this well-studied molecule is fragmented...
  5. ncbi Differences among group A streptococcus epidemiological landscapes: consequences for M protein-based vaccines?
    Pierre R Smeesters
    Bacterial Pathogenesis Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland 4029, Australia
    Expert Rev Vaccines 8:1705-20. 2009
    ..In this review, we have compiled GAS epidemiological studies from several countries around the world to highlight the consequences on the theoretical efficacy of two different M protein-based vaccine strategies...
  6. ncbi Group A Streptococcus virulence and host factors in two toddlers with rheumatic fever following toxic shock syndrome
    Pierre Robert Smeesters
    Laboratoire de Génétique et Physiologie Bactérienne, Institut de Biologie et de Médecine Moléculaires, Faculte des Sciences, Universite Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, B6041 Gosselies, Belgium
    Int J Infect Dis 14:e403-9. 2010
    ..The present report describes the bacterial and host determinants in non-related toddlers who developed RF diagnostic criteria after toxic shock syndrome (TSS)...
  7. ncbi Emerging fluoroquinolone-non-susceptible group A streptococci in two different paediatric populations
    Pierre Robert Smeesters
    Laboratoire de Génétique et Physiologie Bactérienne, Institut de Biologie et de Médecine Moléculaires IBMM, Faculte des Sciences, Universite Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, 6041 Gosselies, Belgium
    Int J Antimicrob Agents 34:44-9. 2009
    ..All the Brazilian and Belgian emm type 6 strains displayed a S79A/F mutation in parC that convincingly explains the non-susceptible phenotype...
  8. ncbi Genetic diversity of Group A Streptococcus M protein: implications for typing and vaccine development
    Pierre R Smeesters
    Laboratoire de Génétique et Physiologie Bactérienne, Institut de Biologie et de Médecine Moléculaires, Faculte des Sciences, Universite Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, 6041 Gosselies, Belgium
    Vaccine 26:5835-42. 2008
    ....
  9. ncbi Differences between Belgian and Brazilian group A Streptococcus epidemiologic landscape
    Pierre Robert Smeesters
    Infectious Diseases Department, Hopital Universitaire des Enfants Reine Fabiola, Universite Libre de Bruxelles, Brussels, Belgium Laboratoire de Génétique des Procaryotes, Institut de Biologie et de Médecine Moléculaires, Universite Libre de Bruxelles, Brussels, Belgium Pediatric Department, Hospital Universitario de Brasilia, Universidade de Brasilia, Brasilia, Brazil
    PLoS ONE 1:e10. 2006
    ..Group A Streptococcus (GAS) clinical and molecular epidemiology varies with location and time. These differences are not or are poorly understood...
  10. ncbi Characterization of novel phages isolated in coagulase-negative staphylococci reveals evolutionary relationships with Staphylococcus aureus phages
    Marie Deghorain
    Laboratoire de Génétique et Physiologie Bactérienne, Faculte de Sciences, IBMM, Universite Libre de Bruxelles, Gosselies, Belgium
    J Bacteriol 194:5829-39. 2012
    ..Our findings support the notion of a possible reciprocal exchange of genes between phages originating from S. aureus and CoNS, which may be of crucial importance for pathogenesis in staphylococci...
  11. ncbi Recombination drives genetic diversification of Streptococcus dysgalactiae subspecies equisimilis in a region of streptococcal endemicity
    David J McMillan
    Bacterial Pathogenesis Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    PLoS ONE 6:e21346. 2011
    ..Our data demonstrate that genetic recombination in endemic regions is more frequent than non-endemic regions, and gives rise to novel local SDSE variants, some of which may have increased fitness or pathogenic potential...
  12. ncbi Carriage-associated Streptocccus pneumoniae serotype 1 in Brussels, Belgium
    Sarah Jourdain
    Laboratoire de Génétique et Physiologie Bactérienne, Institut de Biologie et de Médecine Moléculaires, Faculte des Sciences, Bruxelles, Belgium
    Pediatr Infect Dis J 32:86-7. 2013
    ..Invasive and colonizing isolates were characterized by both antibiotic resistance profile and multilocus sequence typing and were shown to share the same backbone (ST306 and ST350)...
  13. ncbi Sequential multiplex PCR assay for determining capsular serotypes of colonizing S. pneumoniae
    Sarah Jourdain
    Laboratoire de Génétique et Physiologie Bactérienne, Institut de Biologie et de Médecine Moléculaires, Universite Libre de Bruxelles, Bruxelles, Belgium
    BMC Infect Dis 11:100. 2011
    ..Serotype determination by conventional method (Quellung reaction) is technically and financially challenging. On the contrary, PCR-based serotyping represents a simple, economic and promising alternative method...
  14. ncbi Characterization of a novel temperate phage originating from a cereulide-producing Bacillus cereus strain
    Pierre R Smeesters
    Laboratoire de Génétique et Physiologie Bactérienne, IBMM, Faculte des Sciences, Universite Libre de Bruxelles, 12 Rue des Professeurs, Jeener et Brachet, 6041 Gosselies, Belgium
    Res Microbiol 162:446-59. 2011
    ..Genome analysis further illustrates the diversity of mobile genetic elements and their plasticity within the B. cereus group...
  15. ncbi Streptococcal skin infection and rheumatic heart disease
    Tom Parks
    Wellcome Trust Centre for Human Genetics, Oxford, UK
    Curr Opin Infect Dis 25:145-53. 2012
    ..In this review, we summarize recent advances in the epidemiology of group A streptococcal skin disease and examine evidence for the relationship between group A streptococcal skin disease and rheumatic fever...
  16. ncbi Pragmatic scoring system for pharyngitis in low-resource settings
    Laure Joachim
    Department of Pediatrics, Queen Fabiola Unversity Children s Hospital, Institute for Molecular Biology and Medicine, Free University of Brussels, Brussels, Belgium
    Pediatrics 126:e608-14. 2010
    ..Our objective was to develop an easy, safe, pragmatic, clinical scoring system that would allow decreases in unnecessary treatment with antimicrobial agents in low-resource settings...