S N Schiffmann

Summary

Country: Belgium

Publications

  1. pmc Expression of Cre recombinase in dopaminoceptive neurons
    Thomas Lemberger
    German Cancer Research Center, 69120 Heidelberg, Germany
    BMC Neurosci 8:4. 2007
  2. pmc Unraveling the differential functions and regulation of striatal neuron sub-populations in motor control, reward, and motivational processes
    Sabrina Ena
    Laboratory of Neurophysiology, School of Medicine, Université Libre de Bruxelles Brussels, Belgium
    Front Behav Neurosci 5:47. 2011
  3. pmc Adenosine A2A receptors and basal ganglia physiology
    S N Schiffmann
    Laboratory of Neurophysiology, Universite Libre de Bruxelles, Campus Erasme, 808 Route de Lennik, CP601, 1070 Brussels, Belgium
    Prog Neurobiol 83:277-92. 2007
  4. ncbi request reprint A2A receptor and striatal cellular functions: regulation of gene expression, currents, and synaptic transmission
    S N Schiffmann
    Laboratory of Neurophysiology, IRIBHM, Universite Libre de Bruxelles, Belgium
    Neurology 61:S24-9. 2003
  5. ncbi request reprint Targeted calretinin expression in granule cells of calretinin-null mice restores normal cerebellar functions
    Bertrand Bearzatto
    Laboratory of Neurophysiology CP601, Universite Libre de Bruxelles, Route de Lennik 808, Brussels 1070, Belgium
    FASEB J 20:380-2. 2006
  6. ncbi request reprint [Changes in neural networks by conditional transgenic approach: a key to our comprehension of neuro-psychiatric disorders in the basal ganglia system]
    S N Schiffmann
    Laboratoire de Neurophysiologie, CP601, Campus Erasme, U L B
    Bull Mem Acad R Med Belg 164:171-8; discussion 178-80. 2009
  7. pmc Impaired motor coordination and Purkinje cell excitability in mice lacking calretinin
    S N Schiffmann
    Brain Research Unit CP601, Universite Libre de Bruxelles, 1070 Brussels, Belgium
    Proc Natl Acad Sci U S A 96:5257-62. 1999
  8. ncbi request reprint Modulation of the voltage-gated sodium current in rat striatal neurons by DARPP-32, an inhibitor of protein phosphatase
    S N Schiffmann
    Brain Research Unit, Universite Libre de Bruxelles, Brussels, Belgium
    Eur J Neurosci 10:1312-20. 1998
  9. ncbi request reprint Acute and chronic caffeine administration differentially alters striatal gene expression in wild-type and adenosine A(2A) receptor-deficient mice
    D Dassesse
    Laboratory of Neurophysiology, Department of Neuroscience, School of Medicine, Universite Libre de Bruxelles, B 1070 Brussels, Belgium
    Synapse 42:63-76. 2001
  10. ncbi request reprint Caffeine-mediated induction of c-fos, zif-268 and arc expression through A1 receptors in the striatum: different interactions with the dopaminergic system
    D Dassesse
    Brain Research Unit and Laboratory of Neuropathology and Neuropeptides Research, School of Medicine, Universite Libre de Bruxelles, Campus Erasme, Brussels, Belgium
    Eur J Neurosci 11:3101-14. 1999

Collaborators

Detail Information

Publications33

  1. pmc Expression of Cre recombinase in dopaminoceptive neurons
    Thomas Lemberger
    German Cancer Research Center, 69120 Heidelberg, Germany
    BMC Neurosci 8:4. 2007
    ..To this purpose, we used as expression vector a 140 kb yeast artificial chromosome (YAC) containing the dopamine D1 receptor gene (Drd1a)...
  2. pmc Unraveling the differential functions and regulation of striatal neuron sub-populations in motor control, reward, and motivational processes
    Sabrina Ena
    Laboratory of Neurophysiology, School of Medicine, Université Libre de Bruxelles Brussels, Belgium
    Front Behav Neurosci 5:47. 2011
    ....
  3. pmc Adenosine A2A receptors and basal ganglia physiology
    S N Schiffmann
    Laboratory of Neurophysiology, Universite Libre de Bruxelles, Campus Erasme, 808 Route de Lennik, CP601, 1070 Brussels, Belgium
    Prog Neurobiol 83:277-92. 2007
    ....
  4. ncbi request reprint A2A receptor and striatal cellular functions: regulation of gene expression, currents, and synaptic transmission
    S N Schiffmann
    Laboratory of Neurophysiology, IRIBHM, Universite Libre de Bruxelles, Belgium
    Neurology 61:S24-9. 2003
    ..Therefore, this receptor is implicated in the induction of corticoaccumbal LTP, an effect that could be related to its involvement in long-term behavioral sensitization to repeated dopaminergic treatment...
  5. ncbi request reprint Targeted calretinin expression in granule cells of calretinin-null mice restores normal cerebellar functions
    Bertrand Bearzatto
    Laboratory of Neurophysiology CP601, Universite Libre de Bruxelles, Route de Lennik 808, Brussels 1070, Belgium
    FASEB J 20:380-2. 2006
    ....
  6. ncbi request reprint [Changes in neural networks by conditional transgenic approach: a key to our comprehension of neuro-psychiatric disorders in the basal ganglia system]
    S N Schiffmann
    Laboratoire de Neurophysiologie, CP601, Campus Erasme, U L B
    Bull Mem Acad R Med Belg 164:171-8; discussion 178-80. 2009
    ....
  7. pmc Impaired motor coordination and Purkinje cell excitability in mice lacking calretinin
    S N Schiffmann
    Brain Research Unit CP601, Universite Libre de Bruxelles, 1070 Brussels, Belgium
    Proc Natl Acad Sci U S A 96:5257-62. 1999
    ..Thus, these results show that calretinin plays a major role at the network level in cerebellar physiology...
  8. ncbi request reprint Modulation of the voltage-gated sodium current in rat striatal neurons by DARPP-32, an inhibitor of protein phosphatase
    S N Schiffmann
    Brain Research Unit, Universite Libre de Bruxelles, Brussels, Belgium
    Eur J Neurosci 10:1312-20. 1998
    ....
  9. ncbi request reprint Acute and chronic caffeine administration differentially alters striatal gene expression in wild-type and adenosine A(2A) receptor-deficient mice
    D Dassesse
    Laboratory of Neurophysiology, Department of Neuroscience, School of Medicine, Universite Libre de Bruxelles, B 1070 Brussels, Belgium
    Synapse 42:63-76. 2001
    ....
  10. ncbi request reprint Caffeine-mediated induction of c-fos, zif-268 and arc expression through A1 receptors in the striatum: different interactions with the dopaminergic system
    D Dassesse
    Brain Research Unit and Laboratory of Neuropathology and Neuropeptides Research, School of Medicine, Universite Libre de Bruxelles, Campus Erasme, Brussels, Belgium
    Eur J Neurosci 11:3101-14. 1999
    ....
  11. ncbi request reprint Inactivation of adenosine A2A receptor impairs long term potentiation in the accumbens nucleus without altering basal synaptic transmission
    P d'Alcantara
    Laboratory of Neurophysiology, Department of Neuroscience, Universite Libre de Bruxelles, Brussels, Begium
    Neuroscience 107:455-64. 2001
    ....
  12. pmc Effect of protein kinase A-induced phosphorylation on the gating mechanism of the brain Na+ channel: model fitting to whole-cell current traces
    P d'Alcantara
    Institut de Recherche Interdisciplinaire en Biologie Humaine et Nucleaire, Faculte de Medecine, Universite Libre de Bruxelles, Brussels, Belgium
    Biophys J 77:204-16. 1999
    ..This conclusion is supported by the analysis of current traces obtained from cells in the presence of a phosphatase inhibitor or loaded with the PKA catalytic unit, and is in agreement with previously reported single channel records...
  13. ncbi request reprint Functional striatal hypodopaminergic activity in mice lacking adenosine A(2A) receptors
    D Dassesse
    European Graduate School of Neuroscience EURON, Laboratory of Neurophysiology, Department of Neuroscience, Universite Libre de Bruxelles, Campus Erasme, 808 Route de Lennik, 1070 Brussels, Belgium
    J Neurochem 78:183-98. 2001
    ....
  14. ncbi request reprint Distribution and ultrastructure of interstitial cells of Cajal in the mouse colon, using antibodies to Kit and Kit(W-lacZ) mice
    J M Vanderwinden
    Laboratoire de Neurophysiologie et Physiopathologie du Système Nerveux, Faculte de Medecine, Universite Libre de Bruxelles, Brussels, Belgium
    Cell Tissue Res 302:155-70. 2000
    ..The interstitial cells of Cajal in the mouse colon mature postnatally. They are organized into a characteristic plexus, close to the nerves with various chemical codings...
  15. ncbi request reprint Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor
    C Ledent
    IRIBHN, Universite Libre de Bruxelles, Campus Erasme, Belgium
    Nature 388:674-8. 1997
    ..The response of A2aR-/- mice to acute pain stimuli was slower. Blood pressure and heart rate were increased, as well as platelet aggregation. The specific A2a agonist CGS 21680 lost its biological activity in all systems tested...
  16. ncbi request reprint The SH2 domain-containing 5-phosphatase SHIP2 is expressed in the germinal layers of embryo and adult mouse brain: increased expression in N-CAM-deficient mice
    E Muraille
    Interdisciplinary Research Institute, , Campus Erasme, Brussels, Belgium
    Neuroscience 105:1019-30. 2001
    ..In conclusion, the close correlation between the pattern of SHIP2 expression in the brain and the proliferative and early differentiative events suggests that the phosphatase SHIP2 may have important roles in neural development...
  17. doi request reprint Distribution of SV2C mRNA and protein expression in the mouse brain with a particular emphasis on the basal ganglia system
    D Dardou
    Laboratory of Neurophysiology, Universite Libre de Bruxelles ULB, 808 Route de Lennik, 1070 Brussels, Belgium
    Brain Res 1367:130-45. 2011
    ....
  18. ncbi request reprint Role of calcium binding proteins in the control of cerebellar granule cell neuronal excitability: experimental and modeling studies
    D Gall
    Laboratoire de Neurophysiologie CP601, Faculte de Medecine, Universite Libre de Bruxelles, Route de Lennik 808, B 1070 Brussels, Belgium
    Prog Brain Res 148:321-8. 2005
    ..We suggest that calcium binding proteins modulate intrinsic neuronal excitability and may therefore play a role in the information processing in the central nervous system...
  19. ncbi request reprint Comparative study of hippocampal neuronal loss and in vivo binding of 5-HT1a receptors in the KA model of limbic epilepsy in the rat
    P Van Bogaert
    PET Biomedical Cyclotron Unit, Hopital Erasme, Brussels, Belgium
    Epilepsy Res 47:127-39. 2001
    ..This effect needs to be further characterized before considering PET determination of hippocampal MPPF binding as a method of post-epileptic neuronal loss assessment...
  20. pmc Impaired long-term potentiation induction in dentate gyrus of calretinin-deficient mice
    S Schurmans
    Institut de Recherches Interdisciplinaires en Biologie Humaine et Nucl eaire IRIBHN, Route de Lennik 808, 1070 Brussels, Belgium
    Proc Natl Acad Sci U S A 94:10415-20. 1997
    ....
  21. ncbi request reprint Modulation of neuronal excitability by intracellular calcium buffering: from spiking to bursting
    C Roussel
    Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Libre de Bruxelles, Route de Lennik 808, B 1070 Bruxelles, Belgium
    Cell Calcium 39:455-66. 2006
    ....
  22. ncbi request reprint Mono- and dual-frequency fast cerebellar oscillation in mice lacking parvalbumin and/or calbindin D-28k
    L Servais
    Laboratoire d Electrophysiologie, Universite de Mons Hainaut, 24 Avenue du Champ de Mars, 7000 Mons, Belgium
    Eur J Neurosci 22:861-70. 2005
    ....
  23. doi request reprint A role for Sv2c in basal ganglia functions
    D Dardou
    Laboratory of Neurophysiology, ULB Neuroscience Institute, Universite Libre de Bruxelles, 808 Route de Lennik, 1070 Brussels, Belgium
    Brain Res 1507:61-73. 2013
    ..These results showed that SV2C, a poorly functionally characterized protein is strongly involved in normal operation of the basal ganglia network and could be also involved in system adaptation in basal ganglia pathological conditions...
  24. pmc The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor
    F Libert
    Institut de Recherche Interdisciplinaire, Faculte de Medecine, Universite Libre de Bruxelles, Belgium
    EMBO J 10:1677-82. 1991
    ..The two molecular species RDC7 and RDC8 correspond clearly to the A1 and A2 receptor entities defined hitherto on a purely pharmacological basis...
  25. ncbi request reprint CD34 immunoreactivity and interstitial cells of Cajal in the human and mouse gastrointestinal tract
    J M Vanderwinden
    Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Libre de Bruxelles, Campus Erasme, Brussels, Belgium
    Cell Tissue Res 302:145-53. 2000
    ..The ontogeny and function of CD34-ir cells in the gut, as well as the origin of gastrointestinal stromal tumors, remain unclear...
  26. ncbi request reprint Tricyclic antidepressant imipramine reduces the insulin secretory rate in islet cells of Wistar albino rats through a calcium antagonistic action
    M H Antoine
    Laboratory of Pharmacology, Faculty of Medicine, CP 617, Universite Libre de Bruxelles, Lennik Street 808, 1070 Brussels, Belgium
    Diabetologia 47:909-16. 2004
    ..Treatments with antidepressants have been associated with modifications in glucose homeostasis. The aim of this study was to assess the effect of imipramine, a tricyclic antidepressant, on insulin-secreting cells...
  27. pmc Control of neuronal excitability by calcium binding proteins: a new mathematical model for striatal fast-spiking interneurons
    D P Bischop
    Laboratoire de Neurophysiologie, Faculte de Medecine, Université Libre de Bruxelles Bruxelles, Belgium
    Front Mol Neurosci 5:78. 2012
    ..Our results show that a variation in the concentration of PV can modulate substantially the intrinsic excitability of the FS interneurons and therefore may be involved in the information processing at the striatal level...
  28. ncbi request reprint Reelin mRNA expression during mouse brain development
    S N Schiffmann
    Laboratoire de Recherche sur le Cerveau, Universite Libre de Bruxelles, Faculté de Médecine Erasme, Belgium
    Eur J Neurosci 9:1055-71. 1997
    ....
  29. pmc An update on adenosine A2A-dopamine D2 receptor interactions: implications for the function of G protein-coupled receptors
    S Ferre
    National Institute on Drug Abuse, IRP, NIH, DHHS, 5500 Nathan Shock Dr, Baltimore, MD 21224, USA
    Curr Pharm Des 14:1468-74. 2008
    ..The analysis of A(2)-D(2) receptor interactions will have implications for the pathophysiology and treatment of basal ganglia disorders and drug addiction...
  30. ncbi request reprint Calretinin expression as a critical component in the control of dentate gyrus long-term potentiation induction in mice
    H Gurden
    Department of Electrophysiology, Rhone Poulenc Rorer S A, Vitry sur Seine, France
    Eur J Neurosci 10:3029-33. 1998
    ..The possible mechanisms leading to the absence of correlation between gene dosage and biological effects are discussed...
  31. ncbi request reprint Dopamine D3 receptor stimulation promotes the proliferation of cells derived from the post-natal subventricular zone
    V Coronas
    CNRS UMR 6187, Universite de Poitiers, France
    J Neurochem 91:1292-301. 2004
    ..These findings provide support for a regulatory role of dopamine over cellular dynamics in post-natal SVZ...
  32. ncbi request reprint Topological analysis of striatal lesions induced by 3-nitropropionic acid in the Lewis rat
    D Blum
    , ULB-Erasme, Bruxelles, Belgium
    Neuroreport 12:1769-72. 2001
    ..Thus, 3NP-treated Lewis rat provides an improved animal model for testing neuroprotective strategies in HD...
  33. ncbi request reprint Interstitial cells of Cajal in the striated musculature of the mouse esophagus
    J J Rumessen
    Department of Gastroenterology, Hvidovre Hospital, Denmark
    Cell Tissue Res 306:1-14. 2001
    ..Interstitial cells of Cajal are scattered between striated muscle cells in the mouse esophagus. They are close to nerves with defined neurochemical coding and could possibly represent specialized esophageal spindle proprioceptors...