E Quertemont

Summary

Country: Belgium

Publications

  1. ncbi request reprint The role of acetaldehyde in the central effects of ethanol
    Etienne Quertemont
    Neuroscience Comportementale et Psychopharmacologie, University of Liege, Liege, Belgium
    Alcohol Clin Exp Res 29:221-34. 2005
  2. ncbi request reprint Is ethanol a pro-drug? Acetaldehyde contribution to brain ethanol effects
    Etienne Quertemont
    Neuroscience Comportementale et Psychopharmacologie, University of Liege, Belgium
    Alcohol Clin Exp Res 29:1514-21. 2005
  3. ncbi request reprint The role of acetaldehyde in the neurobehavioral effects of ethanol: a comprehensive review of animal studies
    Etienne Quertemont
    Laboratoire de Neurosciences Comportementales, et Psychopharmacologie, Universite de Liege, Boulevard du Rectorat 5 B32, 4000 Liege, Belgium
    Prog Neurobiol 75:247-74. 2005
  4. ncbi request reprint Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism
    E Quertemont
    Laboratoire de Neurosciences Comportementales et Psychopharmacologie, Universite de Liege, Liege, Belgium
    Mol Psychiatry 9:570-81. 2004
  5. ncbi request reprint Behavioral characterization of acetaldehyde in C57BL/6J mice: locomotor, hypnotic, anxiolytic and amnesic effects
    Etienne Quertemont
    Laboratoire de Neurosciences Comportementales et Psychopharmacologie, Universite de Liege, Boulevard du Rectorat 5 B32, 4000 Liege, Belgium
    Psychopharmacology (Berl) 177:84-92. 2004
  6. ncbi request reprint Is ethanol a pro-drug? The role of acetaldehyde in the central effects of ethanol
    Etienne Quertemont
    Laboratoire de Neurosciences Comportementales et Psychopharmacologie, Universite de Liege, Boulevard du Rectorat 5 B32, B 4000 Liege, Belgium
    Trends Pharmacol Sci 25:130-4. 2004
  7. ncbi request reprint Response to novelty as a predictor for drug effects: the pitfalls of some correlational studies
    Etienne Quertemont
    Laboratoire de Neurosciences Comportementales et Psychopharmacologie, Universite de Liege, Boulevard du Rectorat 5 B32, 4000 Liege, Belgium
    Psychopharmacology (Berl) 173:221-4; discussion 225-6. 2004
  8. ncbi request reprint Discriminative stimulus effects of ethanol with a conditioned taste aversion procedure: lack of acetaldehyde substitution
    E Quertemont
    Universite de Liege, Département des Sciences Cognitives, Laboratoire de Neuroscience Comportementale et de Psychopharmacologie, Liege, Belgium
    Behav Pharmacol 14:343-50. 2003
  9. ncbi request reprint Systemic osmotic manipulations modulate ethanol-induced taurine release: a brain microdialysis study
    Etienne Quertemont
    Biologie du Comportement, Universite Catholique de Louvain, Place Croix du Sud 1, 1348 Louvain la Neuve, Belgium
    Alcohol 29:11-9. 2003
  10. ncbi request reprint Taurine and ethanol preference: a microdialysis study using Sardinian alcohol-preferring and non-preferring rats
    E Quertemont
    Biologie du Comportement, Universite Catholique de Louvain, Place Croix du Sud 1, 1348 Louvain la Neuve, Belgium
    Eur Neuropsychopharmacol 10:377-83. 2000

Detail Information

Publications31

  1. ncbi request reprint The role of acetaldehyde in the central effects of ethanol
    Etienne Quertemont
    Neuroscience Comportementale et Psychopharmacologie, University of Liege, Liege, Belgium
    Alcohol Clin Exp Res 29:221-34. 2005
    ..McBride, Zachary A. Rodd, Avram Goldstein, Alejandro Zaffaroni and Ting-Kai Li; and (5) Acetaldehyde increases dopaminergic transmission in the limbic system, by Milena Pisano and Marco Diana...
  2. ncbi request reprint Is ethanol a pro-drug? Acetaldehyde contribution to brain ethanol effects
    Etienne Quertemont
    Neuroscience Comportementale et Psychopharmacologie, University of Liege, Belgium
    Alcohol Clin Exp Res 29:1514-21. 2005
    ..Rodd and Richard R. Bell; (4) Molecular and biochemical changes associated with acetaldehyde in human alcoholism and alcohol abuse, by C. J. Peter Eriksson...
  3. ncbi request reprint The role of acetaldehyde in the neurobehavioral effects of ethanol: a comprehensive review of animal studies
    Etienne Quertemont
    Laboratoire de Neurosciences Comportementales, et Psychopharmacologie, Universite de Liege, Boulevard du Rectorat 5 B32, 4000 Liege, Belgium
    Prog Neurobiol 75:247-74. 2005
    ..Finally, we review current evidence about the central mechanisms of action of acetaldehyde...
  4. ncbi request reprint Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism
    E Quertemont
    Laboratoire de Neurosciences Comportementales et Psychopharmacologie, Universite de Liege, Liege, Belgium
    Mol Psychiatry 9:570-81. 2004
    ..However, the peripheral effects of acetaldehyde might also be dependent upon its peak blood concentrations and its rate of accumulation, with a narrow range of blood acetaldehyde concentrations being reinforcing...
  5. ncbi request reprint Behavioral characterization of acetaldehyde in C57BL/6J mice: locomotor, hypnotic, anxiolytic and amnesic effects
    Etienne Quertemont
    Laboratoire de Neurosciences Comportementales et Psychopharmacologie, Universite de Liege, Boulevard du Rectorat 5 B32, 4000 Liege, Belgium
    Psychopharmacology (Berl) 177:84-92. 2004
    ..Acetaldehyde, the first metabolite of ethanol, was recently suggested to contribute to many behavioral effects of ethanol, although few studies have directly investigated the behavioral effects of acetaldehyde itself...
  6. ncbi request reprint Is ethanol a pro-drug? The role of acetaldehyde in the central effects of ethanol
    Etienne Quertemont
    Laboratoire de Neurosciences Comportementales et Psychopharmacologie, Universite de Liege, Boulevard du Rectorat 5 B32, B 4000 Liege, Belgium
    Trends Pharmacol Sci 25:130-4. 2004
  7. ncbi request reprint Response to novelty as a predictor for drug effects: the pitfalls of some correlational studies
    Etienne Quertemont
    Laboratoire de Neurosciences Comportementales et Psychopharmacologie, Universite de Liege, Boulevard du Rectorat 5 B32, 4000 Liege, Belgium
    Psychopharmacology (Berl) 173:221-4; discussion 225-6. 2004
  8. ncbi request reprint Discriminative stimulus effects of ethanol with a conditioned taste aversion procedure: lack of acetaldehyde substitution
    E Quertemont
    Universite de Liege, Département des Sciences Cognitives, Laboratoire de Neuroscience Comportementale et de Psychopharmacologie, Liege, Belgium
    Behav Pharmacol 14:343-50. 2003
    ..Acetaldehyde up to toxic doses did not substitute for the ethanol discriminative stimulus in the DTA protocol, when non-specific effects were carefully controlled...
  9. ncbi request reprint Systemic osmotic manipulations modulate ethanol-induced taurine release: a brain microdialysis study
    Etienne Quertemont
    Biologie du Comportement, Universite Catholique de Louvain, Place Croix du Sud 1, 1348 Louvain la Neuve, Belgium
    Alcohol 29:11-9. 2003
    ..Ethanol-induced cell swelling probably activates volume-sensitive channels, and taurine passively diffuses outside the cells along its concentration gradient...
  10. ncbi request reprint Taurine and ethanol preference: a microdialysis study using Sardinian alcohol-preferring and non-preferring rats
    E Quertemont
    Biologie du Comportement, Universite Catholique de Louvain, Place Croix du Sud 1, 1348 Louvain la Neuve, Belgium
    Eur Neuropsychopharmacol 10:377-83. 2000
    ....
  11. ncbi request reprint Dissociation between the locomotor and anxiolytic effects of acetaldehyde in the elevated plus-maze: evidence that acetaldehyde is not involved in the anxiolytic effects of ethanol in mice
    Sophie Tambour
    Laboratoire de Neurosciences Comportementales et Psychopharmacologie, Universite de Liege, Boulevard du Rectorat 5 B32, 4000 Liege, Belgium
    Eur Neuropsychopharmacol 15:655-62. 2005
    ..Together, the results of the present study indicate that acetaldehyde is not involved in ethanol-induced anxiolytic effects, although it may be involved in its sedative/hypolocomotor effects...
  12. ncbi request reprint Conditioned stimulus preference after acetaldehyde but not ethanol injections
    E Quertemont
    Biologie du Comportement, Universite Catholique de Louvain, Place Croix du Sud 1, 1348, Louvain la Neuve, Belgium
    Pharmacol Biochem Behav 68:449-54. 2001
    ..The present study clearly shows that systemic acetaldehyde injections induced significant stimulus preferences. This suggests that acetaldehyde may be, at least in part, responsible for the reinforcing effects of alcohol intake...
  13. ncbi request reprint Role of catalase in ethanol-induced conditioned taste aversion: a study with 3-amino-1,2,4-triazole
    Etienne Quertemont
    Biologie du Comportement, Universite Catholique de Louvain, Place Croix du Sud 1, 1348, Louvain la Neuve, Belgium
    Drug Alcohol Depend 70:77-83. 2003
    ..The present study argues against a role for brain acetaldehyde in ethanol's aversive effects but in favor of its involvement in ethanol rewarding properties...
  14. ncbi request reprint Locomotor effects of ethanol and acetaldehyde after peripheral and intraventricular injections in Swiss and C57BL/6J mice
    Sophie Tambour
    Unité de Recherche en Psychologie Expérimentale et Neurosciences Cognitives URPENC, Universite de Liege, Boulevard du Rectorat 5 B32, B 4000 Liege, Belgium
    Behav Brain Res 172:145-54. 2006
    ..Additionally, the present study shows that the stimulant properties of acetaldehyde, even after direct infusion into the brain, are not as obvious as previously speculated...
  15. ncbi request reprint Discriminative stimulus effects of ethanol: lack of interaction with taurine
    E Quertemont
    Laboratoire de Psychopharmacologie, Universite de Liege, Liege, Belgium
    Behav Pharmacol 15:495-501. 2004
    ..e. positive modulation of GABA(A) receptor, that mediate its discriminative stimulus effects...
  16. ncbi request reprint Role of acetaldehyde in mediating the pharmacological and behavioral effects of alcohol
    Etienne Quertemont
    Centre de Neurosciences Cognitives et Comportementales, Universite de Liege, Liege, Belgium
    Alcohol Res Health 29:258-65. 2006
    ..Current evidence suggests that the contribution of acetaldehyde to alcohol's effects is best explained by a process in which acetaldehyde modulates, rather than mediates, some of alcohol's effects...
  17. ncbi request reprint Acamprosate reduces context-dependent ethanol effects
    Etienne Quertemont
    Biologie de Comportement, Universite Catholique de Louvain, Louvain la Neuve, Belgium
    Psychopharmacology (Berl) 164:10-8. 2002
    ..Acamprosate was recently suggested to reduce the effects of environmental stimuli previously associated with ethanol administrations. This action is believed to contribute to the clinical benefits of acamprosate treatment in alcoholics...
  18. ncbi request reprint Effects of cyanamide and acetaldehyde accumulation on the locomotor stimulant and sedative effects of ethanol in mice
    Sophie Tambour
    Center of Cognitive and Behavioral Neurosciences, University of Liege, Liege, Belgium
    Behav Pharmacol 18:777-84. 2007
    ..It is concluded that in vivo the effects of cyanamide are predominantly due to the inhibition of the enzyme aldehyde dehydrogenase, rather than to its effects on catalase...
  19. doi request reprint Parametric analysis of the development and expression of ethanol-induced behavioral sensitization in female Swiss mice: effects of dose, injection schedule, and test context
    Vincent Didone
    Centre de Neurosciences Cognitives et Comportementales, Universite de Liege, Boulevard du Rectorat 5 B32, 4000, Liege, Belgium
    Psychopharmacology (Berl) 201:249-60. 2008
    ..Repeated administrations of ethanol induce a progressive and enduring increase in its locomotor stimulant effects, a phenomenon termed behavioral sensitization that has not been systematically characterized...
  20. doi request reprint Effects of the H3 receptor inverse agonist thioperamide on cocaine-induced locomotion in mice: role of the histaminergic system and potential pharmacokinetic interactions
    Christian Brabant
    Centre de Neurosciences Cognitives et Comportementales CNCC, Universite de Liege, Boulevard du Rectorat 5 B 32, 4000 Liege, Belgium
    Psychopharmacology (Berl) 202:673-87. 2009
    ..The present study examined the involvement of the histaminergic system in these effects of thioperamide in mice...
  21. ncbi request reprint Effects of the H3-receptor inverse agonist thioperamide on the psychomotor effects induced by acutely and repeatedly given cocaine in C57BL/6J mice
    Christian Brabant
    Unité de Recherche en Psychologie Expérimentale et de Neurosciences Cognitives, URPENC, Universite de Liege, Boulevard du Rectorat B 32, B 4000 Liege, Belgium
    Pharmacol Biochem Behav 83:561-9. 2006
    ....
  22. ncbi request reprint The psychostimulant and rewarding effects of cocaine in histidine decarboxylase knockout mice do not support the hypothesis of an inhibitory function of histamine on reward
    Christian Brabant
    Unité de Recherche en Psychologie Expérimentale et en Neurosciences Cognitives URPENC, Universite de Liege, Boulevard du Rectorat, B 32, 4000, Liege, Belgium
    Psychopharmacology (Berl) 190:251-63. 2007
    ..If histamine actually plays an inhibitory role in reward, then it would be expected that mice lacking histamine would be more sensitive to the behavioral effects of cocaine...
  23. ncbi request reprint The H3 antagonist thioperamide reveals conditioned preference for a context associated with an inactive small dose of cocaine in C57BL/6J mice
    Christian Brabant
    Behavioural Neuroscience and Psychopharmacology Laboratory, University of Liege, Liege, Belgium
    Behav Brain Res 160:161-8. 2005
    ..Our results strongly suggest that H3 antagonists potentiate the stimulant and reinforcing effects of cocaine in mice...
  24. ncbi request reprint Evidence that the relations between novelty-induced activity, locomotor stimulation and place preference induced by cocaine qualitatively depend upon the dose: a multiple regression analysis in inbred C57BL/6J mice
    Christian Brabant
    Département de Sciences Cognitives, Unité de Neurosciences Comportementales and Psychopharmacologie Expérimentale, Universite de Liege, Boulevard du Rectorat Bt 32, B 4000 Liege, Belgium
    Behav Brain Res 158:201-10. 2005
    ..The relationships between locomotor response to novelty and both cocaine-induced stimulant and rewarding effects can be differentially affected by the dose in inbred C57BL/6J mice...
  25. doi request reprint Acetaldehyde and the hypothermic effects of ethanol in mice
    Catherine Closon
    Centre de Neurosciences Cognitives et Comportementales, Universite de Liege, Liege, Belgium
    Alcohol Clin Exp Res 33:2005-14. 2009
    ..The aim of the present study is to better understand the hypothermic effects of acetaldehyde and the possible contribution of acetaldehyde in ethanol-induced hypothermia, especially under conditions leading to acetaldehyde accumulation...
  26. ncbi request reprint Brain ethanol concentrations and ethanol discrimination in rats: effects of dose and time
    Etienne Quertemont
    Laboratoire de Psychopharmacologie, Universite de Liege, Boulevard du Rectorat 5 B32, 4000, Liege, Belgium
    Psychopharmacology (Berl) 168:262-70. 2003
    ..The discriminative stimulus effects of ethanol are also time-dependent, although very few studies have investigated the time course of ethanol discriminations...
  27. ncbi request reprint Differential taurine responsiveness to ethanol in high- and low-alcohol sensitive rats: a brain microdialysis study
    Etienne Quertemont
    Biologie du Comportement, Universite Catholique de Louvain, Place Croix du Sud 1, 1348 Louvain la Neuve, Belgium
    Eur J Pharmacol 444:143-50. 2002
    ..Such an effect remains unexplained but suggests that discrepancies between the results of previous microdialysate studies may be related to differences in the ethanol sensitivities of various rat strains...
  28. ncbi request reprint Role of acetaldehyde in the discriminative stimulus effects of ethanol
    Etienne Quertemont
    Biologie du Comportement, Universite Catholique de Louvain, Louvain la Neuve, Belgium
    Alcohol Clin Exp Res 26:812-7. 2002
    ..However, a role for acetaldehyde in mediating the discriminative stimulus effects of ethanol remains unclear...
  29. ncbi request reprint Influence of the dose and the number of drug-context pairings on the magnitude and the long-lasting retention of cocaine-induced conditioned place preference in C57BL/6J mice
    Christian Brabant
    Département de Sciences Cognitives, Unité de Neurosciences Comportementales, et de Psychopharmacologie Expérimentale, Universite de Liege, Boulevard du Rectorat B 32, 4000 Liege, Belgium
    Psychopharmacology (Berl) 180:33-40. 2005
    ..The place conditioning procedure is increasingly used to study relapse in drug seeking in mice. However, the retention course of drug-induced place preference has not been systematically characterized...
  30. ncbi request reprint Preclinical and clinical pharmacology of alcohol dependence
    Sophie Tambour
    Unité de Recherche en Psychologie Expérimentale et Neurosciences Cognitives URPENC, Universite de Liege, Boulevard du Rectorat 5 B32, B 4000 Liege, Belgium
    Fundam Clin Pharmacol 21:9-28. 2007
    ..These new drugs in the field of alcohol pharmacotherapy are also discussed, together with their mechanisms of action...
  31. ncbi request reprint Role of acetaldehyde in ethanol-induced conditioned taste aversion in rats
    M Dolores Escarabajal
    Area de Psicobiologia, Universidad de Jaen, 23071, Jaen, Spain
    Psychopharmacology (Berl) 167:130-6. 2003
    ..In spite of many recent studies on the effects of acetaldehyde, it is still unclear whether acetaldehyde mediates the reinforcing and/or aversive effects of ethanol...