Pierre Oswald

Summary

Country: Belgium

Publications

  1. ncbi Current issues in bipolar disorder: a critical review
    Pierre Oswald
    Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Brussels, Belgium
    Eur Neuropsychopharmacol 17:687-95. 2007
  2. ncbi Molecular genetics of affective disorders
    Pierre Oswald
    Department of Psychiatry, Erasme Hospital, Free University of Brussels, Belgium
    Int J Neuropsychopharmacol 6:155-69. 2003
  3. ncbi Lack of association between the 5HT2A receptor polymorphism (T102C) and unipolar affective disorder in a multicentric European study
    Pierre Oswald
    University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Brussels, Belgium
    Eur Neuropsychopharmacol 13:365-8. 2003
  4. ncbi Non-replication of the brain-derived neurotrophic factor (BDNF) association in bipolar affective disorder: a Belgian patient-control study
    Pierre Oswald
    Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Brussels, Belgium
    Am J Med Genet B Neuropsychiatr Genet 129:34-5. 2004
  5. ncbi Molecular genetics of affective disorders
    Pierre Oswald
    Department of Psychiatry, Erasme Hospital, Free University of Brussels, 808 Route de Lennik, B 1070, Brussels, Belgium
    Prog Neuropsychopharmacol Biol Psychiatry 28:865-77. 2004
  6. ncbi No implication of brain-derived neurotrophic factor (BDNF) gene in unipolar affective disorder: evidence from Belgian first and replication patient-control studies
    Pierre Oswald
    Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, 808 Route de Lennik, B 1070, Brussels, Belgium
    Eur Neuropsychopharmacol 15:491-5. 2005
  7. ncbi Patient-control association study of substance P-related genes in unipolar and bipolar affective disorders
    Julien Mendlewicz
    Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Belgium
    Int J Neuropsychopharmacol 8:505-13. 2005
  8. doi Switching antidepressant class does not improve response or remission in treatment-resistant depression
    Daniel Souery
    Laboratoire de Psychologie Médicale, Universite Libre de Bruxelles, and Centre Européen de Psychologie Médicale PsyPluriel, Brussels, Belgium
    J Clin Psychopharmacol 31:512-6. 2011
  9. ncbi Brain-derived neurotrophic factor gene polymorphisms: influence on treatment response phenotypes of major depressive disorder
    Neslihan Aygun Kocabas
    Laboratoire de Neurologie Expérimentale, Universite Libre de Bruxelles, Laboratoire de Neurologie Expérimentale, Campus Hôpital Erasme C2 124, 808 Route de Lennik, 1070 Bruxelles, Belgium
    Int Clin Psychopharmacol 26:1-10. 2011
  10. ncbi Clinical factors associated with treatment resistance in major depressive disorder: results from a European multicenter study
    Daniel Souery
    Department of Psychiatry, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    J Clin Psychiatry 68:1062-70. 2007

Detail Information

Publications15

  1. ncbi Current issues in bipolar disorder: a critical review
    Pierre Oswald
    Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Brussels, Belgium
    Eur Neuropsychopharmacol 17:687-95. 2007
    ..Recent research has also allowed for the redefinition of the concept of mood stabilizer and for improving existing guidelines on the clinical management of Bipolar disorder...
  2. ncbi Molecular genetics of affective disorders
    Pierre Oswald
    Department of Psychiatry, Erasme Hospital, Free University of Brussels, Belgium
    Int J Neuropsychopharmacol 6:155-69. 2003
    ..Improved methodologies and updated tools in genetic studies will improve in the future our knowledge of affective disorders...
  3. ncbi Lack of association between the 5HT2A receptor polymorphism (T102C) and unipolar affective disorder in a multicentric European study
    Pierre Oswald
    University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Brussels, Belgium
    Eur Neuropsychopharmacol 13:365-8. 2003
    ..Therefore, to exclude the implication of HTR2A in UPAD, this result must be replicated in larger samples and in other populations using the transmission disequilibrium test and different polymorphisms around HTR2A...
  4. ncbi Non-replication of the brain-derived neurotrophic factor (BDNF) association in bipolar affective disorder: a Belgian patient-control study
    Pierre Oswald
    Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Brussels, Belgium
    Am J Med Genet B Neuropsychiatr Genet 129:34-5. 2004
    ..44). We failed to replicate previous findings implicating BDNF in the aetiology of BPAD. However, BDNF remains an interesting target for future genetic studies and should be tested in prospective pharmacogenetic therapeutic trials...
  5. ncbi Molecular genetics of affective disorders
    Pierre Oswald
    Department of Psychiatry, Erasme Hospital, Free University of Brussels, 808 Route de Lennik, B 1070, Brussels, Belgium
    Prog Neuropsychopharmacol Biol Psychiatry 28:865-77. 2004
    ..In addition, recent advances in technology, such as microarrays, provide new tools in psychiatric genetics. These different approaches offer a new optimism era in the search of genetic factors in AD...
  6. ncbi No implication of brain-derived neurotrophic factor (BDNF) gene in unipolar affective disorder: evidence from Belgian first and replication patient-control studies
    Pierre Oswald
    Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, 808 Route de Lennik, B 1070, Brussels, Belgium
    Eur Neuropsychopharmacol 15:491-5. 2005
    ..A statistical difference was found between cases and controls in the first sample but not in the second. These results are not in favour of an implication of BDNF in UPAD but need to be replicated before final conclusion...
  7. ncbi Patient-control association study of substance P-related genes in unipolar and bipolar affective disorders
    Julien Mendlewicz
    Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Belgium
    Int J Neuropsychopharmacol 8:505-13. 2005
    ..In conclusion, our findings do not support a major contribution of SP-related genes in UPAD and BPAD, but provides some evidence of an ace influence in treatment response to antidepressants...
  8. doi Switching antidepressant class does not improve response or remission in treatment-resistant depression
    Daniel Souery
    Laboratoire de Psychologie Médicale, Universite Libre de Bruxelles, and Centre Européen de Psychologie Médicale PsyPluriel, Brussels, Belgium
    J Clin Psychopharmacol 31:512-6. 2011
    ....
  9. ncbi Brain-derived neurotrophic factor gene polymorphisms: influence on treatment response phenotypes of major depressive disorder
    Neslihan Aygun Kocabas
    Laboratoire de Neurologie Expérimentale, Universite Libre de Bruxelles, Laboratoire de Neurologie Expérimentale, Campus Hôpital Erasme C2 124, 808 Route de Lennik, 1070 Bruxelles, Belgium
    Int Clin Psychopharmacol 26:1-10. 2011
    ..Despite the limited power of analysis, our results suggest that these three SNPs may play a role in antidepressant treatment response phenotypes in MDD...
  10. ncbi Clinical factors associated with treatment resistance in major depressive disorder: results from a European multicenter study
    Daniel Souery
    Department of Psychiatry, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    J Clin Psychiatry 68:1062-70. 2007
    ....
  11. doi Citalopram versus desipramine in treatment resistant depression: effect of continuation or switching strategies: a randomized open study
    Daniel Souery
    Laboratoire de Psychologie Médicale, Universite Libre de Bruxelles, and Centre Européen de Psychologie Médicale PsyPluriel, Brussels, Belgium
    World J Biol Psychiatry 12:364-75. 2011
    ..The result goes in the opposite direction to that predicted by current guidelines...
  12. ncbi Molecular genetics in the analysis of suicide
    Daniel Souery
    Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Universite Libre de Bruxelles, Belgium
    Ann Med 35:191-6. 2003
    ..In spite of those observations having some limitations, it appears that genetic factors are a serious risk factor, besides environmental aspects of suicidal behavior...
  13. doi Dysbindin gene (DTNBP1) in major depressive disorder (MDD) patients: lack of association with clinical phenotypes
    Neslihan Aygun Kocabas
    Fonds de la Recherche Scientifique FNRS, Laboratoire de Neurologie Expérimentale, Universite Libre de Bruxelles, Belgium
    World J Biol Psychiatry 11:985-90. 2010
    ..Dystrobrevin binding protein 1 (Dysbindin) is a plausible candidate gene for major depressive disorders (MDD) due to its involvement in synaptic signaling, plasticity and localization in the brain...
  14. doi The impact of catechol-O-methyltransferase SNPs and haplotypes on treatment response phenotypes in major depressive disorder: a case-control association study
    Neslihan Aygun Kocabas
    aFonds de la Recherche Scientifique FNRS, Laboratoire de Neurologie Expérimentale, Universite Libre de Bruxelles, Bruxelles, Belgium
    Int Clin Psychopharmacol 25:218-27. 2010
    ..Despite the limited power of our analysis, this finding suggests that the polymorphic COMT gene that influences catecholaminergic neurotransmission may play a role in the individual response to antidepressants...
  15. ncbi Shortened onset of action of antidepressants in major depression using acetylsalicylic acid augmentation: a pilot open-label study
    Julien Mendlewicz
    Department of Psychiatry, Erasme Hospital, Free University of Brussels, Belgium
    Int Clin Psychopharmacol 21:227-31. 2006
    ..Potential physiological and biochemical mechanisms may involve an anti-inflammatory and/or neurotrophic effect...