Michel C Milinkovitch

Summary

Country: Belgium

Publications

  1. ncbi request reprint Escaping the mouse trap: the selection of new Evo-Devo model species
    Michel C Milinkovitch
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine, Universite Libre de Bruxelles, Gosselies, Belgium
    J Exp Zool B Mol Dev Evol 308:337-46. 2007
  2. pmc Giant Galápagos tortoises; molecular genetic analyses identify a trans-island hybrid in a repatriation program of an endangered taxon
    Michel C Milinkovitch
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine, Universite Libre de Bruxelles, rue Jeener and Brachet 12, 6041 Gosselies, Belgium
    BMC Ecol 7:2. 2007
  3. pmc Genetic analysis of a successful repatriation programme: giant Galápagos tortoises
    Michel C Milinkovitch
    Laboratory of Evolutionary Genetics, Institute of Molecular Biology and Medicine, Free University of Brussels, cp 300, rue Jeener and Brachet 12, B 6041 Gosselies, Belgium
    Proc Biol Sci 271:341-5. 2004
  4. ncbi request reprint Molecular phylogenetic analyses indicate extensive morphological convergence between the "yeti" and primates
    Michel Milinkovitch
    Evolutionary Genetics, Institute of Molecular Biology and Medicine, Free University of Brussels ULB, Gosselies, Belgium
    Mol Phylogenet Evol 31:1-3. 2004
  5. ncbi request reprint Inferring contemporary levels of gene flow and demographic history in a local population of the leaf beetle Gonioctena olivacea from mitochondrial DNA sequence variation
    Patrick Mardulyn
    Laboratory of Evolutionary Genetics, Universite Libre de Bruxelles, Rue Jeener et Brachet 12, 6041 Gosselies, Belgium
    Mol Ecol 14:1641-53. 2005
  6. ncbi request reprint A non-linear optimization procedure to estimate distances and instantaneous substitution rate matrices under the GTR model
    Daniele Catanzaro
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine, IBMM, Université Libre de Bruxelles CP300, Rue Jeener et Brachet 12, B 6041, Gosselies, Belgium
    Bioinformatics 22:708-15. 2006
  7. ncbi request reprint MANTIS: a phylogenetic framework for multi-species genome comparisons
    Athanasia C Tzika
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine, Universite Libre de Bruxelles, Belgium
    Bioinformatics 24:151-7. 2008
  8. doi request reprint Population structure of an endemic vulnerable species, the Jamaican boa (Epicrates subflavus)
    Athanasia C Tzika
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine, Universite Libre de Bruxelles, B6041 Gosselies, Belgium
    Mol Ecol 17:533-44. 2008
  9. ncbi request reprint Evaluating intraspecific "network" construction methods using simulated sequence data: do existing algorithms outperform the global maximum parsimony approach?
    Insa Cassens
    Laboratory of Evolutionary Genetics, Institute of Molecular Biology and Medicine, Universite Libre de Bruxelles, Rue Jeener et Brachet 12, 6041 Gosselies, Belgium
    Syst Biol 54:363-72. 2005
  10. pmc An ant colony optimization algorithm for phylogenetic estimation under the minimum evolution principle
    Daniele Catanzaro
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine IBMM, Université Libre de Bruxelles U, L, B, CP300, Rue Jeener et Brachet 12, B 6041, Gosselies, Belgium
    BMC Evol Biol 7:228. 2007

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Escaping the mouse trap: the selection of new Evo-Devo model species
    Michel C Milinkovitch
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine, Universite Libre de Bruxelles, Gosselies, Belgium
    J Exp Zool B Mol Dev Evol 308:337-46. 2007
    ....
  2. pmc Giant Galápagos tortoises; molecular genetic analyses identify a trans-island hybrid in a repatriation program of an endangered taxon
    Michel C Milinkovitch
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine, Universite Libre de Bruxelles, rue Jeener and Brachet 12, 6041 Gosselies, Belgium
    BMC Ecol 7:2. 2007
    ..However, analysis of 118 samples from released individuals indicated that the bias sex ratio and large variance in reproductive success among the 15 breeders has severely reduced the effective population size (Ne)...
  3. pmc Genetic analysis of a successful repatriation programme: giant Galápagos tortoises
    Michel C Milinkovitch
    Laboratory of Evolutionary Genetics, Institute of Molecular Biology and Medicine, Free University of Brussels, cp 300, rue Jeener and Brachet 12, B 6041 Gosselies, Belgium
    Proc Biol Sci 271:341-5. 2004
    ..Contributions of the breeders are highly skewed. This has led to a further loss of genetic variation that is detrimental to the long-term survival of the population. Modifications to the breeding programme could alleviate this problem...
  4. ncbi request reprint Molecular phylogenetic analyses indicate extensive morphological convergence between the "yeti" and primates
    Michel Milinkovitch
    Evolutionary Genetics, Institute of Molecular Biology and Medicine, Free University of Brussels ULB, Gosselies, Belgium
    Mol Phylogenet Evol 31:1-3. 2004
  5. ncbi request reprint Inferring contemporary levels of gene flow and demographic history in a local population of the leaf beetle Gonioctena olivacea from mitochondrial DNA sequence variation
    Patrick Mardulyn
    Laboratory of Evolutionary Genetics, Universite Libre de Bruxelles, Rue Jeener et Brachet 12, 6041 Gosselies, Belgium
    Mol Ecol 14:1641-53. 2005
    ..However, a metapopulation structure alone (without the need to invoke a population expansion event) cannot be dismissed as the cause of this star shape...
  6. ncbi request reprint A non-linear optimization procedure to estimate distances and instantaneous substitution rate matrices under the GTR model
    Daniele Catanzaro
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine, IBMM, Université Libre de Bruxelles CP300, Rue Jeener et Brachet 12, B 6041, Gosselies, Belgium
    Bioinformatics 22:708-15. 2006
    ..Although it has been previously noted that the causes for intractability are caused by the impossibility of computing the logarithm of a matrix characterised by negative eigenvalues, the issue has not been investigated further...
  7. ncbi request reprint MANTIS: a phylogenetic framework for multi-species genome comparisons
    Athanasia C Tzika
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine, Universite Libre de Bruxelles, Belgium
    Bioinformatics 24:151-7. 2008
    ..Furthermore, the field would greatly benefit from a better integration of this wealth of data with evolutionary concepts...
  8. doi request reprint Population structure of an endemic vulnerable species, the Jamaican boa (Epicrates subflavus)
    Athanasia C Tzika
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine, Universite Libre de Bruxelles, B6041 Gosselies, Belgium
    Mol Ecol 17:533-44. 2008
    ....
  9. ncbi request reprint Evaluating intraspecific "network" construction methods using simulated sequence data: do existing algorithms outperform the global maximum parsimony approach?
    Insa Cassens
    Laboratory of Evolutionary Genetics, Institute of Molecular Biology and Medicine, Universite Libre de Bruxelles, Rue Jeener et Brachet 12, 6041 Gosselies, Belgium
    Syst Biol 54:363-72. 2005
    ..Moreover, our analyses indicate that, when internal node haplotypes are not sampled, the median-joining and MP methods provide the best estimate of the true genealogy whereas the minimum-spanning algorithm shows very poor performances...
  10. pmc An ant colony optimization algorithm for phylogenetic estimation under the minimum evolution principle
    Daniele Catanzaro
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine IBMM, Université Libre de Bruxelles U, L, B, CP300, Rue Jeener et Brachet 12, B 6041, Gosselies, Belgium
    BMC Evol Biol 7:228. 2007
    ..The major difficulty for its application is that the number of possible phylogenies grows exponentially with the number of taxa analyzed and the minimum evolution principle is known to belong to the NRho- hard class of problems...
  11. pmc Controlling population evolution in the laboratory to evaluate methods of historical inference
    Patrick Mardulyn
    Laboratory of Evolutionary Genetics, Universite Libre de Bruxelles, Gosselies, Belgium
    PLoS ONE 3:e2960. 2008
    ....
  12. ncbi request reprint Evidence for male dispersal along the coasts but no migration in pelagic waters in dusky dolphins (Lagenorhynchus obscurus)
    Insa Cassens
    Laboratory of Evolutionary Genetics, Institute of Molecular Biology and Medicine, Universite Libre de Bruxelles, rue Jeener and Brachet 12, 6041 Gosselies, Belgium
    Mol Ecol 14:107-21. 2005
    ..Only the Peruvian dusky dolphin stock is highly differentiated, especially at mitochondrial loci, suggesting that major fluctuations in its population size have led to an increased rate of genetic drift...
  13. ncbi request reprint Structure and evolution of the mitochondrial control region of leaf beetles (Coleoptera: Chrysomelidae): a hierarchical analysis of nucleotide sequence variation
    Patrick Mardulyn
    Free University of Brussels, Rue Jeener et Brachet 12, 6041, Gosselies, Belgium
    J Mol Evol 56:38-45. 2003
    ..Our analyses allowed us to identify portions of the control region with enough variation for population genetic or phylogeographic studies...
  14. ncbi request reprint OligoFaktory: a visual tool for interactive oligonucleotide design
    Colas Schretter
    Unit of Evolutionary Genetics, Institute of Molecular Biology and Medicine, Free University of Brussels, Gosselies, Belgium
    Bioinformatics 22:115-6. 2006
    ..The design pipeline can use BLAST servers to evaluate specificity of selected oligonucleotides. AVAILABILITY: The web portal http://ueg.ulb.ac.be/oligofaktory/; the software for Macintosh: http://www.oligofaktory.org/..
  15. ncbi request reprint Separate-component-stabilization system for protein and DNA production without the use of antibiotics
    Cédric Y Szpirer
    Laboratory of Evolutionary Genetics, Institute of Molecular Biology and Medicine, Universite Libre de Bruxelles, Charleroi Gosselies, Belgium
    Biotechniques 38:775-81. 2005
    ..Finally, we demonstrate that the SCS system increases by five the yield in DNA production, a result especially important for the design and production of gene therapy constructs void of any antibiotic resistance gene...
  16. pmc Automated discovery and phylogenetic analysis of new toxin-antitoxin systems
    Julien Guglielmini
    Laboratory of Evolutionary Genetics, Institute for Molecular Biology and Medicine, Universite Libre de Bruxelles ULB, 12 rue Jeener and Brachet, 6041 Gosselies, Belgium
    BMC Microbiol 8:104. 2008
    ..Thus, a cell exhibiting a TA system on a plasmid is 'condemned' either not to loose it or to die...
  17. ncbi request reprint A hidden Markov model for progressive multiple alignment
    Ari Löytynoja
    Unit of Evolutionary Genetics, Free University of Brussels ULB, cp 300, Institute of Molecular Biology and Medicine, rue Jeener and Brachet 12, B 6041 Gosselies, Belgium
    Bioinformatics 19:1505-13. 2003
    ..Probabilistic approaches providing measures of global and/or local reliability of individual solutions would constitute valuable developments...
  18. pmc The metapopulation genetic algorithm: An efficient solution for the problem of large phylogeny estimation
    Alan R Lemmon
    Laboratory of Evolutionary Genetics, Free University of Brussels ULB, cp 300, Institute of Molecular Biology and Medicine, rue Jeener and Brachet 12, B 6041 Gosselies, Belgium
    Proc Natl Acad Sci U S A 99:10516-21. 2002
    ..Branch support values produced by the metapopulation genetic algorithm might closely approximate the posterior probabilities of the corresponding branches...
  19. ncbi request reprint Investigation of the population genetic structure and mating system in the ant Pheidole pallidula
    Denis Fournier
    Department of Animal Biology, Unit of Animal Communities CP 160 12, Free University of Brussels ULB, Avenue F D Roosevelt, 50, B 1050 Brussels, Belgium
    Mol Ecol 11:1805-14. 2002
    ..Finally, our analyses indicate that colonies are genetically differentiated and form a population exhibiting significant isolation-by-distance, suggesting that some colonies originate through budding...
  20. doi request reprint Characterization of microsatellite loci in the European pond turtle Emys orbicularis
    Claudio Ciofi
    Molecular Ecology Laboratory, Department of Animal Biology and Genetics, University of Florence, Via Romana 17, 50125 Florence, Italy, Laboratory of Evolutionary Genetics, Institute of Molecular Biology and Medicine, Universite Libre de Bruxelles, rue Jeener and Brachet 12, B 6041 Gosselies, Belgium, Wetland of Kerkini Management Authority, Kerkini, Kato Poroia, Greece
    Mol Ecol Resour 9:189-91. 2009
    ..738 and 0.921. This novel set of loci will be particularly useful to assess fine-scale population structure and for parentage analysis in E. orbicularis...
  21. pmc Dual chemical sequestration: a key mechanism in transitions among ecological specialization
    Arnaud Termonia
    Unit of Evolutionary Genetics, Institute of Molecular Biology and Medicine, Free University of Brussels Université Libre de Bruxelles, cp 300, rue Jeener and Brachet 12, B 6041 Gosselies, Belgium
    Proc Biol Sci 269:1-6. 2002
    ..The analyses indicate that dual sequestration could be the key mechanistic means by which transitions among ecological specializations (i.e. restricted host-plant affiliations) are made possible...
  22. doi request reprint Development of 10 highly-polymorphic microsatellite markers in the vulnerable Galápagos land iguanas (genus Conolophus)
    Sabrina F P Rosa
    Laboratory of Evolutionary Genetic, Institute of Molecular Biology and Medicine, Universite Libre de Bruxelles, Rue Jeener et Brachet 12, 6041 Gosselies, Belgium Laboratory of Natural and Artificial Evolution, Sciences III, Quai Ernest Ansermet 30, 1211 Geneva 4, Switzerland
    Mol Ecol Resour 9:376-9. 2009
    ..These markers will be useful for Conolophus population genetic analyses as well as for guiding ongoing captive breeding programmes...
  23. ncbi request reprint Mitochondrial genome and nuclear sequence data support myzostomida as part of the annelid radiation
    Christoph Bleidorn
    Unit of Evolutionary Biology Systematic Zoology, Institute of Biochemistry and Biology, University of Potsdam, Potsdam Golm, Germany
    Mol Biol Evol 24:1690-701. 2007
    ..Using Bayes factor comparison, alternative hypotheses are shown to lack support. Thus, myzostomids probably evolved from a segmented ancestor and gained a derived anatomy during their long evolutionary history as echinoderm symbionts...
  24. ncbi request reprint Phylogeny and biogeography of a cosmopolitan frog radiation: Late cretaceous diversification resulted in continent-scale endemism in the family ranidae
    Franky Bossuyt
    Biology Department, Unit of Ecology and Systematics, Vrije Universiteit Brussel, Pleinlaan 2, B 1050 Brussels, Belgium
    Syst Biol 55:579-94. 2006
    ..Most importantly, all hypotheses make clear predictions as to where to expect key fossils and where to sample other living ranids, and thus constitute a strong basis for further research...
  25. ncbi request reprint Local endemism within the Western Ghats-sri Lanka biodiversity hotspot
    Franky Bossuyt
    Biology Department, Unit of Ecology and Systematics, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium
    Science 306:479-81. 2004
    ..Future conservation programs for the subcontinent should take into account such patterns of local endemism at the finest scale at which they may occur...
  26. pmc Molecular phylogenetic analyses indicate a wide and ancient radiation of African hepatitis delta virus, suggesting a deltavirus genus of at least seven major clades
    Nadjia Radjef
    Laboratoire de Bacteriologie, virologie hygiène, Hopital Avicenne, EA3406 Agents Transmissibles et Hôtes, Signalisation Cellulaire, Oncogenèse, Universite Paris 13, Bobigny, France
    J Virol 78:2537-44. 2004
    ..These results relate the geographic distribution of HDV more closely to the genetic variability of its helper HBV...
  27. ncbi request reprint Microsatellite analysis of genetic divergence among populations of giant Galápagos tortoises
    Claudio Ciofi
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520 8106, USA
    Mol Ecol 11:2265-83. 2002
    ..Our study complements previous investigation based on mtDNA diversity and provides further information that may help devising tortoise management plans...
  28. ncbi request reprint Conceptual bases for quantifying the role of the environment on gene evolution: the participation of positive selection and neutral evolution
    Anthony Levasseur
    Phylogenomics Laboratory, EA 3781 Evolution Biologique Université de Provence, Case 19, Pl V Hugo, 13331 Marseille Cedex 03, France
    Biol Rev Camb Philos Soc 82:551-72. 2007
    ..Therefore, the second aim herein is to review evidence for the mechanisms leading to fixation...
  29. ncbi request reprint Molecular phylogenetic analyses indicate multiple independent emergences of parasitism in Myzostomida (Protostomia)
    Deborah Lanterbecq
    Marine Biology Laboratory, University of Mons Hainaut, 6 Avenue du Champ de Mars, Life Sciences Building, 7000 Mons, Belgium
    Syst Biol 55:208-27. 2006
    ....