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Genomes and Genes | I MassatSummaryCountry: Belgium Publications
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Publications
5-HT2a receptor polymorphism gene in bipolar disorder and harm avoidance personality traitS Blairy
Department of Psychiatry, Free University of Brussels, Erasme Hospital, Belgium
Am J Med Genet 96:360-4. 2000..Despite the limited sample size, these results exclude a major effect of the 5-HTR2a polymorphism on bipolar disorder and HA personality trait but not a minor effect...- Tryptophan hydroxylase polymorphism and suicidality in unipolar and bipolar affective disorders: a multicenter association studyD Souery
Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Brussels, Belgium
Biol Psychiatry 49:405-9. 2001..Several studies have investigated the possible role of TPH polymorphisms in affective disorders and suicidal behavior... - Temperament and Character Inventory (TCI) personality profile and sub-typing in alcoholic patients: a controlled studyP Basiaux
Free University of Brussels, Brugmann University Hospital, Psychiatry and Medical Psychology Department, Place Van Gehuchten 4, 1020 Brussels, Belgium
Alcohol Alcohol 36:584-7. 2001..These results in part support Cloninger's typology, and the TCI data add to evidence concerning a higher probability of personality disorder in alcohol-dependent patients, particularly those with early-onset... - Excess of allele1 for alpha3 subunit GABA receptor gene (GABRA3) in bipolar patients: a multicentric association studyI Massat
Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Belgium
Mol Psychiatry 7:201-7. 2002..00002). Our findings suggest that the GABRA3 polymorphism may confer susceptibility to or may be in linkage disequilibrium with another gene involved in the genetic etiology of BPAD... - A European multicenter association study of HTR2A receptor polymorphism in bipolar affective disorderI Massat
Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Brussels, Belgium
Am J Med Genet 96:136-40. 2000..These results indicate that, in our sample, the 5-HT2A receptor polymorphism studied is unlikely to play a major role in the genetic susceptibility to BPAD. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:136-140, 2000... - Association between COMT (Val158Met) functional polymorphism and early onset in patients with major depressive disorder in a European multicenter genetic association studyI Massat
Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Belgium
Mol Psychiatry 10:598-605. 2005..The COMT gene may have complex and pleiotropic effects on susceptibility and symptomatology of neuropsychiatric disorders... - Lack of association between GABRA3 and unipolar affective disorder: a multicentre studyI Massat
Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, 808 Route de Lennik, B 1070 Brussels, Belgium
Int J Neuropsychopharmacol 4:273-8. 2001..Our negative results suggest that GABRA3 does not confer susceptibility nor is it in linkage disequilibrium with another close gene involved in the genetic aetiology of UPAD... - Positive association of dopamine D2 receptor polymorphism with bipolar affective disorder in a European Multicenter Association Study of affective disordersIsabelle Massat
Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Brussels, Belgium
Am J Med Genet 114:177-85. 2002..Our large European sample allowed for replicating of some previous reported positive findings obtained in other study populations... - Tyrosine hydroxylase polymorphism and phenotypic heterogeneity in bipolar affective disorder: a multicenter association studyD Souery
Department of Psychiatry, University Clinics of Brussels, Erasme Hospital, Free University of Brussels, Brussels, Belgium
Am J Med Genet 88:527-32. 1999..The results of this association study do not confirm the possible implication of TH polymorphism in the susceptibility to BPAD... - A novel CpG-associated brain-expressed candidate gene for chromosome 18q-linked bipolar disorderD Goossens
Department of Molecular Genetics, Flanders Interuniversity Institute for Biotechnology VIB, University of Antwerp UIA, Antwerpen, Belgium
Mol Psychiatry 8:83-9. 2003..A total of nine single nucleotide polymorphisms (SNPs) were identified. Five SNPs predicted an amino acid change, of which two were present in BP patients but not in 163 control individuals... - Variability of 5-HT2C receptor cys23ser polymorphism among European populations and vulnerability to affective disorderB Lerer
Biological Psychiatry Laboratory, Hadassah Medical Organization, Jerusalem, Israel
Mol Psychiatry 6:579-85. 2001..34, df 1, P = 0.006) and BP (chi(2) = 5.45, df 1, P = 0.02) patients. These findings support a possible role for genetically based structural variation in 5-HT2C receptors in the pathogenesis of major affective disorder... - HTR2C (cys23ser) polymorphism influences early onset in bipolar patients in a large European multicenter association studyI Massat
Mol Psychiatry 12:797-8. 2007 - Self-esteem, social adjustment and suicidality in affective disordersE G Daskalopoulou
University Mental Health Research Institute, Athens University Medical School, Eginition Hospital, 72-74, Vas Sofias Avenue, 11528, Athens, Greece
Eur Psychiatry 17:265-71. 2002..It is concluded that low SE lasting into remission seems to be related to the expression of suicidality during depressive episodes of bipolar patients, while no similar pattern is evident in unipolar patients...