Olivier Le Bon

Summary

Country: Belgium

Publications

  1. ncbi Contribution of sleep research to the development of new antidepressants
    Olivier Le Bon
    Universite Libre de Bruxelles, Brussels, Belgium
    Dialogues Clin Neurosci 7:305-13. 2005
  2. ncbi Ultradian cycles in mice: definitions and links with REMS and NREMS
    O Le Bon
    CHU Tivoli, Universite Libre de Bruxelles, av Max Buset 34, 7100, La Louviere, Belgium
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 193:1021-32. 2007
  3. ncbi Cognitive impairment in fatigue and sleepiness associated conditions
    Daniel Neu
    Brugmann University Hospital, Sleep Laboratory and Unit for Chronobiology U78, Department of Psychiatry, Universite Libre De Bruxelles U L B, Brussels, Belgium
    Psychiatry Res 189:128-34. 2011
  4. ncbi Are patients with chronic fatigue syndrome just 'tired' or also 'sleepy'?
    Daniel Neu
    University Hospital Brugmann, Sleep Laboratory, Universite Libre de Bruxelles ULB, Brussels, Belgium
    J Sleep Res 17:427-31. 2008
  5. ncbi High slow-wave sleep and low-light sleep: chronic fatigue syndrome is not likely to be a primary sleep disorder
    Daniel Neu
    Brugmann University Hospital, Sleep Laboratory, and Unit for Chronobiology U78, Universite Libre De Bruxelles U L B, Brussels, Belgium
    J Clin Neurophysiol 26:207-12. 2009
  6. ncbi Relationships between the number of ultradian cycles and key sleep variables in outpatients with major depressive disorder
    Olivier Le Bon
    CHU Tivoli, Department of Psychiatry, Universite Libre de Bruxelles, av Max Buset 34, 7100 La Louviere, Belgium
    Psychiatry Res 165:60-7. 2009
  7. ncbi Do 'sleepy' and 'tired' go together? Rasch analysis of the relationships between sleepiness, fatigue and nonrestorative sleep complaints in a nonclinical population sample
    Daniel Neu
    Sleep Laboratory and Unit for Chronobiology U78, Brugmann University Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neuroepidemiology 35:1-11. 2010
  8. ncbi Major depression in males: effects of age, severity and adaptation on sleep variables
    Philippe Hubain
    Department of Psychiatry, Erasme Hospital, , Brussels, Belgium
    Psychiatry Res 145:169-77. 2006
  9. ncbi Sleep quality perception in the chronic fatigue syndrome: correlations with sleep efficiency, affective symptoms and intensity of fatigue
    Daniel Neu
    Sleep Laboratory, Department of Psychiatry, University Hospital Brugmann, Brussels, Belgium
    Neuropsychobiology 56:40-6. 2007
  10. ncbi Ultra-slow delta power in chronic fatigue syndrome
    Olivier Le Bon
    Brugmann University Hospital, Sleep Laboratory and Unit for Chronobiology U78, Universite Libre De Bruxelles U L B, Brussels, Belgium
    Psychiatry Res 200:742-7. 2012

Detail Information

Publications16

  1. ncbi Contribution of sleep research to the development of new antidepressants
    Olivier Le Bon
    Universite Libre de Bruxelles, Brussels, Belgium
    Dialogues Clin Neurosci 7:305-13. 2005
    ....
  2. ncbi Ultradian cycles in mice: definitions and links with REMS and NREMS
    O Le Bon
    CHU Tivoli, Universite Libre de Bruxelles, av Max Buset 34, 7100, La Louviere, Belgium
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 193:1021-32. 2007
    ..This convergence between monophasic and polyphasic patterns supports the central role played by REMS in sleep alternation...
  3. ncbi Cognitive impairment in fatigue and sleepiness associated conditions
    Daniel Neu
    Brugmann University Hospital, Sleep Laboratory and Unit for Chronobiology U78, Department of Psychiatry, Universite Libre De Bruxelles U L B, Brussels, Belgium
    Psychiatry Res 189:128-34. 2011
    ..In our sample cognitive impairment and psychomotor performance were worse when associated to sleepiness in SAHS than with fatigue in CFS...
  4. ncbi Are patients with chronic fatigue syndrome just 'tired' or also 'sleepy'?
    Daniel Neu
    University Hospital Brugmann, Sleep Laboratory, Universite Libre de Bruxelles ULB, Brussels, Belgium
    J Sleep Res 17:427-31. 2008
    ..Despite possible overlap in symptoms and signs of both daytime conditions, our data indirectly support the clinical distinction between fatigue and sleepiness...
  5. ncbi High slow-wave sleep and low-light sleep: chronic fatigue syndrome is not likely to be a primary sleep disorder
    Daniel Neu
    Brugmann University Hospital, Sleep Laboratory, and Unit for Chronobiology U78, Universite Libre De Bruxelles U L B, Brussels, Belgium
    J Clin Neurophysiol 26:207-12. 2009
    ..Anxiety, but not depression symptoms were more intense in the CFS group. The distribution of nonrapid eye movement sleep in CFS differs sizeably from what can be observed in a primary sleep disorder...
  6. ncbi Relationships between the number of ultradian cycles and key sleep variables in outpatients with major depressive disorder
    Olivier Le Bon
    CHU Tivoli, Department of Psychiatry, Universite Libre de Bruxelles, av Max Buset 34, 7100 La Louviere, Belgium
    Psychiatry Res 165:60-7. 2009
    ..Also, when the RL is shorter, there are more ultradian cycles than when the RL is long. This adds an interesting element in the elucidation of the physiological meaning of anomalies of RL...
  7. ncbi Do 'sleepy' and 'tired' go together? Rasch analysis of the relationships between sleepiness, fatigue and nonrestorative sleep complaints in a nonclinical population sample
    Daniel Neu
    Sleep Laboratory and Unit for Chronobiology U78, Brugmann University Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neuroepidemiology 35:1-11. 2010
    ..We propose to use Rasch analysis-based methods to study the interrelations of fatigue, sleepiness and NRS...
  8. ncbi Major depression in males: effects of age, severity and adaptation on sleep variables
    Philippe Hubain
    Department of Psychiatry, Erasme Hospital, , Brussels, Belgium
    Psychiatry Res 145:169-77. 2006
    ..This sleep reduction affected both REMS and NREMS, in comparable percentages. This supports the hypothesis of a hyperarousal possibly linked to stress...
  9. ncbi Sleep quality perception in the chronic fatigue syndrome: correlations with sleep efficiency, affective symptoms and intensity of fatigue
    Daniel Neu
    Sleep Laboratory, Department of Psychiatry, University Hospital Brugmann, Brussels, Belgium
    Neuropsychobiology 56:40-6. 2007
    ..Furthermore, correlations of subjective fatigue, PSQI, affective symptoms and objective parameters such as sleep efficiency are poorly described in the literature...
  10. ncbi Ultra-slow delta power in chronic fatigue syndrome
    Olivier Le Bon
    Brugmann University Hospital, Sleep Laboratory and Unit for Chronobiology U78, Universite Libre De Bruxelles U L B, Brussels, Belgium
    Psychiatry Res 200:742-7. 2012
    ..From a neurophysiological standpoint, lower ultra-slow wave power may indicate abnormalities in the oscillations in membrane potential or a failure in neural recruitment in those with CFS...
  11. ncbi Clinical complaints of daytime sleepiness and fatigue: how to distinguish and treat them, especially when they become 'excessive' or 'chronic'?
    Daniel Neu
    Brugmann University Hospital, Sleep Laboratory and Unit for Chronobiology U78, Universite Libre de Bruxelles, Brussels, Belgium
    Acta Neurol Belg 110:15-25. 2010
    ..Clinical research and practice should systematically investigate both conditions with adequate measurement tools. Behavioural medicine is certainly underestimated, especially in the management of chronic daytime fatigue...
  12. ncbi Neurocognitive determinants of novelty and sensation-seeking in individuals with alcoholism
    Xavier Noel
    Psychological Medicine Laboratory, Campus Brugmann, Universite Libre de Bruxelles, Brussels, Belgium
    Alcohol Alcohol 46:407-15. 2011
    ..However, little is known about the specific and common cognitive processes associated with NS and sensation-seeking personality traits in detoxified sober alcoholic abusers...
  13. ncbi Inverse association between Slow Wave Activity per cycle and the number of ultradian sleep cycles per night in healthy humans
    Olivier Le Bon
    Sleep Research Unit, Brugmann University Hospital, Universite Libre de Bruxelles, CHU Brugmann S78, Place Van Gehuchten 4, 1020 Bruxelles, Belgium
    Clin Neurophysiol 116:1493-500. 2005
    ..Comparisons of sleep Slow Wave Activity (SWA) during successive sleep cycles rely on the assumption that SWA in a given cycle is independent of the number of ultradian cycles present in a night. This assumption was evaluated here...
  14. ncbi Double-blind, placebo-controlled study of the efficacy of trazodone in alcohol post-withdrawal syndrome: polysomnographic and clinical evaluations
    Olivier Le Bon
    Brugmann University Hospital, CHU Brugmann S78, Universite Libre de Bruxelles, 1040 Brussels, Belgium
    J Clin Psychopharmacol 23:377-83. 2003
    ..Hamilton and Clinical Global scales were better for the TRZ group. TRZ is thus a potential option in the treatment of alcohol post-withdrawal insomnia...
  15. ncbi First-night effect in the chronic fatigue syndrome
    Olivier Le Bon
    Department of Psychiatry, CHU Brugmann S48, Place Van Gehuchten 4, 1020 Brussels, Belgium
    Psychiatry Res 120:191-9. 2003
    ..Chronic fatigue syndrome must thus be added on the list of conditions where a clinically significant habituation effect takes place...
  16. ncbi Sleep microstructure around sleep onset differentiates major depressive insomnia from primary insomnia
    Luc Staner
    FORENAP Institute for Research in Neurosciences, Neuropharmacology and Psychiatry, Centre Hospitalier, Rouffach, France
    J Sleep Res 12:319-30. 2003
    ..This study supports the idea that different mechanisms are implicated in sleep disturbances experienced by primary insomniacs and major depressive insomniacs...