Steven Laureys

Summary

Country: Belgium

Publications

  1. ncbi request reprint The neural correlate of (un)awareness: lessons from the vegetative state
    Steven Laureys
    Cyclotron Research Center and Department of Neurology, University of Liege, Sart Tilman B30, 4000 Liege, Belgium
    Trends Cogn Sci 9:556-9. 2005
  2. doi request reprint Perception of pain in the minimally conscious state with PET activation: an observational study
    Melanie Boly
    Coma Science Group, Cyclotron Research Center, University of Liege, Belgium
    Lancet Neurol 7:1013-20. 2008
  3. pmc Connectivity changes underlying spectral EEG changes during propofol-induced loss of consciousness
    Melanie Boly
    Coma Science Group, Cyclotron Research Centre and Neurology Department, University of Liège and Sart Tilman Hospital, 4000 Liege, Belgium
    J Neurosci 32:7082-90. 2012
  4. doi request reprint A French validation study of the Coma Recovery Scale-Revised (CRS-R)
    Caroline Schnakers
    Coma Science Group, Cyclotron Research Centre, University of Liege, Liege, Belgium
    Brain Inj 22:786-92. 2008
  5. doi request reprint Detecting consciousness in a total locked-in syndrome: an active event-related paradigm
    Caroline Schnakers
    Coma Science Group, Cyclotron Research Centre, Sart Tilman, B30, University of Liege, 4000 Liege, Belgium
    Neurocase 15:271-7. 2009
  6. pmc Visual fixation in the vegetative state: an observational case series PET study
    Marie Aurelie Bruno
    Coma Science Group and Cyclotron Research Centre, University of Liege, Liege, Belgium
    BMC Neurol 10:35. 2010
  7. ncbi request reprint Neural substrates of phonological and lexicosemantic representations in Alzheimer's disease
    Frederic Peters
    Cyclotron Research Centre, University of Liege, Belgium
    Hum Brain Mapp 30:185-99. 2009
  8. doi request reprint Preserved feedforward but impaired top-down processes in the vegetative state
    Melanie Boly
    Coma Science Group, Cyclotron Research Centre and Neurology Department, University of Liège and CHU Sart Tilman Hospital, 4000 Liege, Belgium
    Science 332:858-62. 2011
  9. ncbi request reprint Automated EEG entropy measurements in coma, vegetative state/unresponsive wakefulness syndrome and minimally conscious state
    Olivia Gosseries
    Coma Science Group, Cyclotron Research Center, University of Liege, Belgium
    Funct Neurol 26:25-30. 2011
  10. doi request reprint Cognitive function in the locked-in syndrome
    Caroline Schnakers
    Cyclotron Research Center, University of Liege, Belgium
    J Neurol 255:323-30. 2008

Detail Information

Publications102 found, 100 shown here

  1. ncbi request reprint The neural correlate of (un)awareness: lessons from the vegetative state
    Steven Laureys
    Cyclotron Research Center and Department of Neurology, University of Liege, Sart Tilman B30, 4000 Liege, Belgium
    Trends Cogn Sci 9:556-9. 2005
    ..Such studies are disentangling the neural correlates of the vegetative state from the minimally conscious state, and have major clinical consequences in addition to empirical importance for the understanding of consciousness...
  2. doi request reprint Perception of pain in the minimally conscious state with PET activation: an observational study
    Melanie Boly
    Coma Science Group, Cyclotron Research Center, University of Liege, Belgium
    Lancet Neurol 7:1013-20. 2008
    ..Therefore, better understanding of cerebral noxious processing in these patients is of clinical, therapeutic, and ethical relevance...
  3. pmc Connectivity changes underlying spectral EEG changes during propofol-induced loss of consciousness
    Melanie Boly
    Coma Science Group, Cyclotron Research Centre and Neurology Department, University of Liège and Sart Tilman Hospital, 4000 Liege, Belgium
    J Neurosci 32:7082-90. 2012
    ..These results emphasize the importance of recurrent corticocortical communication in the maintenance of consciousness and suggest a direct effect of propofol on cortical dynamics...
  4. doi request reprint A French validation study of the Coma Recovery Scale-Revised (CRS-R)
    Caroline Schnakers
    Coma Science Group, Cyclotron Research Centre, University of Liege, Liege, Belgium
    Brain Inj 22:786-92. 2008
    ....
  5. doi request reprint Detecting consciousness in a total locked-in syndrome: an active event-related paradigm
    Caroline Schnakers
    Coma Science Group, Cyclotron Research Centre, Sart Tilman, B30, University of Liege, 4000 Liege, Belgium
    Neurocase 15:271-7. 2009
    ..This study shows that our active event-related paradigm allowed to identify voluntary brain activity in a patient who would behaviorally be diagnosed as comatose...
  6. pmc Visual fixation in the vegetative state: an observational case series PET study
    Marie Aurelie Bruno
    Coma Science Group and Cyclotron Research Centre, University of Liege, Liege, Belgium
    BMC Neurol 10:35. 2010
    ..e., represents "automatic" subcortical processing) or is a sufficient sign of consciousness and higher order cortical processing...
  7. ncbi request reprint Neural substrates of phonological and lexicosemantic representations in Alzheimer's disease
    Frederic Peters
    Cyclotron Research Centre, University of Liege, Belgium
    Hum Brain Mapp 30:185-99. 2009
    ..Overall, the results suggest that AD patients use altered pathways to process phonological and lexicosemantic information, possibly related to a progressive loss of specialization of phonological and lexicosemantic neural networks...
  8. doi request reprint Preserved feedforward but impaired top-down processes in the vegetative state
    Melanie Boly
    Coma Science Group, Cyclotron Research Centre and Neurology Department, University of Liège and CHU Sart Tilman Hospital, 4000 Liege, Belgium
    Science 332:858-62. 2011
    ..This result emphasizes the importance of top-down projections in recurrent processing that involve high-order associative cortices for conscious perception...
  9. ncbi request reprint Automated EEG entropy measurements in coma, vegetative state/unresponsive wakefulness syndrome and minimally conscious state
    Olivia Gosseries
    Coma Science Group, Cyclotron Research Center, University of Liege, Belgium
    Funct Neurol 26:25-30. 2011
    ..Future studies are needed before using this tool in routine clinical practice, and these should seek to improve automated EEG quantification paradigms in order to reduce the remaining false negative and false positive findings...
  10. doi request reprint Cognitive function in the locked-in syndrome
    Caroline Schnakers
    Cyclotron Research Center, University of Liege, Belgium
    J Neurol 255:323-30. 2008
    ..Classically, communication remains possible by means of spared vertical eye movements and/or blinking. To allow assessing cognitive functions in LIS patients, we propose here a neuropsychological testing based on eye-coded communication...
  11. ncbi request reprint Cerebral processing of auditory and noxious stimuli in severely brain injured patients: differences between VS and MCS
    Melanie Boly
    University of Liege, Belgium
    Neuropsychol Rehabil 15:283-9. 2005
    ..However, in the absence of a generally accepted neural correlate of consciousness as measured by functional neuroimaging, clinical assessment remains the gold standard for the evaluation and management of severely brain damaged patients...
  12. ncbi request reprint Involvement of both prefrontal and inferior parietal cortex in dual-task performance
    Fabienne Collette
    Department of Neuropsychology, University of Liege, Belgium
    Brain Res Cogn Brain Res 24:237-51. 2005
    ..Moreover, the involvement of a parietal area in the dual task is in keeping with the hypothesis that a parieto-frontal network sustains executive functioning...
  13. ncbi request reprint Exploring the unity and diversity of the neural substrates of executive functioning
    Fabienne Collette
    Neuropsychology Unit, University of Liege, Liege, Belgium
    Hum Brain Mapp 25:409-23. 2005
    ..The results of this neuroimaging study are in agreement with cognitive studies demonstrating that executive functioning is characterized by both unity and diversity of processes...
  14. ncbi request reprint Cerebral correlates of delta waves during non-REM sleep revisited
    Thien Thanh Dang-Vu
    Cyclotron Research Centre, University of Liege, Belgium
    Neuroimage 28:14-21. 2005
    ..Consequently, this rCBF distribution might preferentially reflect a particular modulation of the cellular processes involved in the generation of cortical delta waves during NREM sleep...
  15. doi request reprint Metabolic activity in external and internal awareness networks in severely brain-damaged patients
    Aurore Thibaut
    Coma Science Group, Cyclotron Research Centre and Neurology Department, University and University Hospital of Liège, 4000 Liege, Belgium
    J Rehabil Med 44:487-94. 2012
    ..This study measured brain metabolism in both networks in patients with severe brain damage...
  16. ncbi request reprint Mapping the updating process: common and specific brain activations across different versions of the running span task
    Fabienne Collette
    Neuropsychology Unit, University of Liege, Liege, Belgium
    Cortex 43:146-58. 2007
    ....
  17. doi request reprint Is there anybody in there? Detecting awareness in disorders of consciousness
    Athena Demertzi
    Coma Science Group, Neurology Department, Cyclotron Research Centre, University of Liege, Liege, Belgium
    Expert Rev Neurother 8:1719-30. 2008
    ....
  18. doi request reprint Reaching across the abyss: recent advances in functional magnetic resonance imaging and their potential relevance to disorders of consciousness
    Andrea Soddu
    Coma Science Group, Cyclotron Research Centre, University of Liege, Belgium
    Prog Brain Res 177:261-74. 2009
    ..In particular, we discuss the potential provided by assessment of these slow spontaneous BOLD fluctuations as a novel tool in assessing the cognitive state and chances of recovery from brain pathologies underlying DOCs...
  19. doi request reprint Two distinct neuronal networks mediate the awareness of environment and of self
    Audrey Vanhaudenhuyse
    University of Liege, Liege, Belgium
    J Cogn Neurosci 23:570-8. 2011
    ....
  20. doi request reprint Breakdown of within- and between-network resting state functional magnetic resonance imaging connectivity during propofol-induced loss of consciousness
    Pierre Boveroux
    Department of Anesthesia and Intensive Care Medicine, University of Liege, Liege, Belgium
    Anesthesiology 113:1038-53. 2010
    ..Resting-state functional magnetic resonance imaging allows investigating whole-brain connectivity changes during pharmacological modulation of the level of consciousness...
  21. doi request reprint Comparison of the Full Outline of UnResponsiveness and Glasgow Liege Scale/Glasgow Coma Scale in an intensive care unit population
    Marie Aurelie Bruno
    Coma Science Group, Cyclotron Research Centre and Neurology Department, University and University Hospital of Liège, Sart Tilman B30, 4000 Liege, Belgium
    Neurocrit Care 15:447-53. 2011
    ..We compared the FOUR and GLS/GCS in intensive care unit patients who were admitted in a comatose state...
  22. doi request reprint Consciousness and cerebral baseline activity fluctuations
    Melanie Boly
    Coma Science Group, Cyclotron Research Center, University of Liege, Liege, Belgium
    Hum Brain Mapp 29:868-74. 2008
    ..We place these findings in light of recent findings on the architecture of spontaneous BOLD fluctuations in the awake human brain, and discuss the possible origins of the observed baseline brain activity fluctuations...
  23. ncbi request reprint Resting state activity in patients with disorders of consciousness
    Andrea Soddu
    Coma Science Group, Cyclotron Research Center, University of Liege, Belgium
    Funct Neurol 26:37-43. 2011
    ....
  24. doi request reprint The Nociception Coma Scale: a new tool to assess nociception in disorders of consciousness
    Caroline Schnakers
    Coma Science Group, Cyclotron Research Centre, University of Liege, Sart Tilman, Liege, Belgium
    Pain 148:215-9. 2010
    ..e., VS or MCS). The NCS constitutes a sensitive clinical tool for assessing nociception in severely brain-injured patients. This scale constitutes the first step to a better management of patients recovering from coma...
  25. ncbi request reprint Cognitive event-related potentials in comatose and post-comatose states
    Audrey Vanhaudenhuyse
    Coma Science Group, Cyclotron Research Centre and Neurology Department, University of Liege, Liege, Belgium
    Neurocrit Care 8:262-70. 2008
    ..In coma-survivors, cognitive potentials are more frequently obtained when using stimuli that are more ecologic or have an emotional content (such as the patient's own name) than when using classical sine tones...
  26. ncbi request reprint Auditory processing in severely brain injured patients: differences between the minimally conscious state and the persistent vegetative state
    Melanie Boly
    Cyclotron Research Center, University of Liege, Liege, Belgium
    Arch Neurol 61:233-8. 2004
    ..The minimally conscious state (MCS) is a recently defined clinical condition; it differs from the persistent vegetative state (PVS) by the presence of inconsistent, but clearly discernible, behavioral evidence of consciousness...
  27. doi request reprint Brain functional integration decreases during propofol-induced loss of consciousness
    Jessica Schrouff
    Cyclotron Research Centre, University of Liege, Liege, Belgium
    Neuroimage 57:198-205. 2011
    ..They stress the important role played by parietal and frontal areas in the generation of consciousness...
  28. pmc Default network connectivity reflects the level of consciousness in non-communicative brain-damaged patients
    Audrey Vanhaudenhuyse
    Coma Science Group, Cyclotron Research Centre, University of Liege, Allee du 6 Aout, B30, Liege, Belgium
    Brain 133:161-71. 2010
    ..Future prospective studies in a larger patient population are needed in order to evaluate the prognostic value of the presented methodology...
  29. doi request reprint Identifying the default-mode component in spatial IC analyses of patients with disorders of consciousness
    Andrea Soddu
    Coma Science Group, Cyclotron Research Centre, University of Liege, Liege, Belgium
    Hum Brain Mapp 33:778-96. 2012
    ..We here aimed to identify the DMN in the challenging patient population of disorders of consciousness encountered following coma...
  30. doi request reprint Locked-in syndrome in children: report of five cases and review of the literature
    Marie Aurelie Bruno
    Coma Science Group, Cyclotron Research Center and Neurology Department, University of Liege, 4000 Luik, Belgium
    Pediatr Neurol 41:237-46. 2009
    ..These findings raise important ethical considerations in terms of quality of life and end-of-life decisions in such challenging cases...
  31. ncbi request reprint Are spatial memories strengthened in the human hippocampus during slow wave sleep?
    Philippe Peigneux
    Cyclotron Research Center, University of Liege, B 4000 Liege, Belgium
    Neuron 44:535-45. 2004
    ....
  32. doi request reprint "Relevance vector machine" consciousness classifier applied to cerebral metabolism of vegetative and locked-in patients
    Christophe L Phillips
    Cyclotron Research Centre, University of Liege, Liege, Belgium
    Neuroimage 56:797-808. 2011
    ..Therefore, RVM classification of cerebral metabolic images obtained in coma survivors could become a useful tool for the automated PET-based diagnosis of altered states of consciousness...
  33. pmc Offline persistence of memory-related cerebral activity during active wakefulness
    Philippe Peigneux
    Cyclotron Research Center, University of Liege, Liege, Belgium
    PLoS Biol 4:e100. 2006
    ..Results indicate that the human brain has already extensively processed recent memories during the first hours of post-training wakefulness, even when simultaneously coping with unrelated cognitive demands...
  34. doi request reprint The effect of clonidine infusion on distribution of regional cerebral blood flow in volunteers
    Vincent Bonhomme
    University Department of Anesthesia and Intensive Care Medicine, CHU de Liege and CHR de la Citadelle, 4000 Liege, Belgium
    Anesth Analg 106:899-909, table of contents. 2008
    ..Our goal in this observational study was to map brain regions whose activity is modified by clonidine infusion so as to better understand its loci of action, especially in relation to sedation...
  35. doi request reprint The problem of aphasia in the assessment of consciousness in brain-damaged patients
    Steve Majerus
    Center for Cognitive and Behavioral Neuroscience and Coma Science Group, University of Liege, Belgium
    Prog Brain Res 177:49-61. 2009
    ..The combined use of behavioral and neuroimaging assessment techniques appears to be particularly promising for disentangling impaired consciousness and aphasia...
  36. ncbi request reprint Residual cognitive function in comatose, vegetative and minimally conscious states
    Steven Laureys
    Cyclotron Research Centre, University of Liege, Belgium
    Curr Opin Neurol 18:726-33. 2005
    ..In addition to novel behavioural 'consciousness-scales', the role of para-clinical markers of consciousness, such as event related potentials and functional neuroimaging is reviewed...
  37. doi request reprint Thalamus, brainstem and salience network connectivity changes during propofol-induced sedation and unconsciousness
    Pieter Guldenmund
    Coma Science Group, Cyclotron Research Center, University of Liege, Liege, Belgium
    Brain Connect 3:273-85. 2013
    ..It furthermore stresses the necessity of also examining resting state connectivity in networks representing arousal, not only those associated with awareness...
  38. doi request reprint Functional neuroanatomy underlying the clinical subcategorization of minimally conscious state patients
    Marie Aurelie Bruno
    Coma Science Group, Cyclotron Research Center, University of Liege, Sart Tilman B30, 4000 Liege, Belgium
    J Neurol 259:1087-98. 2012
    ..MCS+ patients showed preserved metabolism and functional connectivity in language networks arguably reflecting some additional higher order or extended consciousness albeit devoid of clinical verbal or nonverbal expression...
  39. doi request reprint A sensitive scale to assess nociceptive pain in patients with disorders of consciousness
    Camille Chatelle
    Coma Science Group, Cyclotron Research Centre, University of Liege, 4000 Liege, Belgium
    J Neurol Neurosurg Psychiatry 83:1233-7. 2012
    ....
  40. doi request reprint Coma and consciousness: paradigms (re)framed by neuroimaging
    Steven Laureys
    Coma Science Group, Cyclotron Research Centre and Neurology Department, University and University Hospital of Liège, 4000 Liege, Belgium
    Neuroimage 61:478-91. 2012
    ..We here review these advances in measurement and the scientific and broader implications of this rapidly progressing field of research...
  41. pmc Hierarchical clustering of brain activity during human nonrapid eye movement sleep
    Melanie Boly
    Cyclotron Research Centre, University of Liege, 4000 Liege, Belgium
    Proc Natl Acad Sci U S A 109:5856-61. 2012
    ..Such modifications in brain connectivity, possibly driven by sleep ultraslow oscillations, could hinder the brain's ability to integrate information and account for decreased consciousness during NREM sleep...
  42. pmc Sleep in disorders of consciousness
    Victor Cologan
    Coma Science Group, Cyclotron Research Center, University of Liege, Belgium
    Sleep Med Rev 14:97-105. 2010
    ..At the present time the interactions of sleep and consciousness in brain-injured patients are a little studied subject but, the authors suggest, a potentially very interesting field of research...
  43. ncbi request reprint Neuroimaging activation studies in the vegetative state: predictors of recovery?
    Haibo Di
    Coma Science Group, Cyclotron Research Centre and Neurology Department, University of Liege, Belgium
    Clin Med 8:502-7. 2008
    ..The clinical application of these functional neuroimaging techniques awaits validation from ongoing multi-centric cohort studies in these challenging patients with chronic disorders of consciousness...
  44. doi request reprint Assessment and detection of pain in noncommunicative severely brain-injured patients
    Caroline Schnakers
    Coma Science Group, Cyclotron Research Centre, Sart Tilman, B30, University of Liege, 4000 Liege, Belgium
    Expert Rev Neurother 10:1725-31. 2010
    ..Pain monitoring in these patients is hence of medical and ethical importance. In this article, we will focus on the possible use of behavioral scales for the assessment and detection of pain in noncommunicative patients...
  45. ncbi request reprint Self-consciousness in non-communicative patients
    Steven Laureys
    Coma Science Group, Cyclotron Research Center and Neurology Department, CHU Sart Tilman Hospital and University of Liège, 4000 Liege, Belgium
    Conscious Cogn 16:722-41; discussion 742-5. 2007
    ..Based on these results we discuss what we currently do and do not know about the functional significance of the neural network involved in "automatic" and "conscious" self-referential processing...
  46. ncbi request reprint Self-referential reflective activity and its relationship with rest: a PET study
    Arnaud D'Argembeau
    Department of Cognitive Sciences, University of Liege, Boulevard du Rectorat, 3 B33, 4000 Liege, Belgium
    Neuroimage 25:616-24. 2005
    ..It is suggested that the VMPFC is crucial for representing knowledge pertaining to the self and that this is an important function of the resting state...
  47. doi request reprint Sleep in the unresponsive wakefulness syndrome and minimally conscious state
    Victor Cologan
    Coma Science Group, Cyclotron Research Center, University of Liege, Belgium
    J Neurotrauma 30:339-46. 2013
    ..The investigation of sleep is a little studied yet simple and informative way to evaluate the integrity of residual brain function in patients with disorders of consciousness with possible clinical diagnostic and prognostic implications...
  48. ncbi request reprint Human cognition during REM sleep and the activity profile within frontal and parietal cortices: a reappraisal of functional neuroimaging data
    Pierre Maquet
    Cyclotron Research Centre, University of Lièege Sart Tilman, 4000 Liege, Belgium
    Prog Brain Res 150:219-27. 2005
    ....
  49. ncbi request reprint Imaging a cognitive model of apraxia: the neural substrate of gesture-specific cognitive processes
    Philippe Peigneux
    Cyclotron Research Centre, University of Liege, Liege, Belgium
    Hum Brain Mapp 21:119-42. 2004
    ..s proposal. Based on the above considerations, we suggest and discuss a revised model for upper limb apraxia that might best account for both brain imaging findings and neuropsychological dissociations reported in the apraxia literature...
  50. pmc Diagnostic accuracy of the vegetative and minimally conscious state: clinical consensus versus standardized neurobehavioral assessment
    Caroline Schnakers
    Coma Science Group, Cyclotron Research Center, University of Liege, Belgium
    BMC Neurol 9:35. 2009
    ..In this study, we compared consensus-based diagnoses of VS and MCS to those based on a well-established standardized neurobehavioral rating scale, the JFK Coma Recovery Scale-Revised (CRS-R)...
  51. pmc Auditory resting-state network connectivity in tinnitus: a functional MRI study
    Audrey Maudoux
    Coma Science Group, Cyclotron Research Centre, University of Liege, Liege, Belgium
    PLoS ONE 7:e36222. 2012
    ....
  52. pmc How should functional imaging of patients with disorders of consciousness contribute to their clinical rehabilitation needs?
    Steven Laureys
    Cyclotron Research Center and Neurology Department, University of Liege, Liege, Belgium
    Curr Opin Neurol 19:520-7. 2006
    ..We discuss the problems of evidence-based neurorehabilitation in disorders of consciousness, and recent functional neuroimaging data obtained in the vegetative state and minimally conscious state...
  53. ncbi request reprint What is it like to be vegetative or minimally conscious?
    Steven Laureys
    Coma Science Group, Cyclotron Research Centre and Neurology Department, University of Liege, Liege, Belgium
    Curr Opin Neurol 20:609-13. 2007
    ..Here we review current possibilities and limitations of clinical and para-clinical assessment of chronic disorders of consciousness...
  54. ncbi request reprint The locked-in syndrome : what is it like to be conscious but paralyzed and voiceless?
    Steven Laureys
    Neurology Department and Cyclotron Research Center, University of Liege, Sart Tilman B30, 4000 Liege, Belgium
    Prog Brain Res 150:495-511. 2005
    ..In our opinion, there is an urgent need for a renewed ethical and medicolegal framework for our care of locked-in patients...
  55. doi request reprint Assessment of consciousness with electrophysiological and neurological imaging techniques
    Marie Aurelie Bruno
    Coma Science Group, Cyclotron Research Centre, University of Liege, Belgium
    Curr Opin Crit Care 17:146-51. 2011
    ....
  56. pmc Tracking the recovery of consciousness from coma
    Steven Laureys
    Cyclotron Research Center and Department of Neurology, University of Liege, Liege, Belgium
    J Clin Invest 116:1823-5. 2006
    ..This case shows that old dogmas need to be oppugned, as recovery with meaningful reduction in disability continued in this case for nearly 2 decades after extremely severe traumatic brain injury...
  57. doi request reprint Brain-computer interfacing in disorders of consciousness
    Camille Chatelle
    Coma Science Group, Cyclotron Research Centre, University of Liege, Liege, Belgium
    Brain Inj 26:1510-22. 2012
    ..These findings have highlighted the potential for the development of simple brain-computer interfaces (BCI) as a diagnosis in behaviourally unresponsive patients...
  58. ncbi request reprint Brain function in the vegetative state
    Steven Laureys
    University of Liege, Cyclotron Research Center, Sart Tilman B30, 4000 Liege, Belgium
    Adv Exp Med Biol 550:229-38. 2004
  59. ncbi request reprint Two aspects of impaired consciousness in Alzheimer's disease
    Eric Salmon
    Cyclotron Research Centre and Department of Neurology, University of Liege, B35 Sart Tilman, B4000 Liege, Belgium
    Prog Brain Res 150:287-98. 2005
    ..g., the temporoparietal junction). We hypothesize that these patients are impaired in the ability to see themselves with a third-person perspective (i.e., being able to see themselves as other people see them)...
  60. ncbi request reprint Orbitofrontal cortex involvement in chronic analgesic-overuse headache evolving from episodic migraine
    Arnaud Fumal
    Department of Neurology, University of Liege, Liege, Belgium
    Brain 129:543-50. 2006
    ..The latter is known to occur in drug dependence and could predispose subgroups of migraineurs to recurrent analgesic overuse...
  61. ncbi request reprint Transcranial magnetic stimulation in disorders of consciousness
    Natallia Lapitska
    Coma Science Group, Cyclotron Research Centre and Neurology Department, University of Liege, Liege, Belgium
    Rev Neurosci 20:235-50. 2009
    ..However, use of this technique in severe brain damage remains methodologically ill-defined and must be further validated prior to clinical application in these challenging patients...
  62. ncbi request reprint Short article one's own face is hard to ignore
    Serge Bredart
    Department of Cognitive Science, University of Liege, Liege, Belgium
    Q J Exp Psychol (Hove) 59:46-52. 2006
    ..We argue that the emotional value or the high familiarity of one's own face may explain its attention-grabbing property...
  63. pmc Unresponsive wakefulness syndrome: a new name for the vegetative state or apallic syndrome
    Steven Laureys
    Dept of Neurology, Cyclotron Research Centre, University Hospital and University of Liège, Belgium
    BMC Med 8:68. 2010
    ..This syndrome has been coined vegetative state. We here present a new name for this challenging neurological condition: unresponsive wakefulness syndrome (abbreviated UWS)...
  64. ncbi request reprint A prominent role for amygdaloid complexes in the Variability in Heart Rate (VHR) during Rapid Eye Movement (REM) sleep relative to wakefulness
    Martin Desseilles
    Cyclotron Research Centre, Liege University, Belgium
    Neuroimage 32:1008-15. 2006
    ..This suggests a functional reorganization of central cardiovascular regulation during REMS...
  65. ncbi request reprint Learned material content and acquisition level modulate cerebral reactivation during posttraining rapid-eye-movements sleep
    Philippe Peigneux
    Cyclotron Research Center and Department of Neuropsychology, Universite de Liege, Belgium
    Neuroimage 20:125-34. 2003
    ..Our data provide the first experimental evidence for a link between behavioral performance and cerebral reactivation during REM sleep...
  66. pmc Central modulation in cluster headache patients treated with occipital nerve stimulation: an FDG-PET study
    Delphine Magis
    University Neurology Department, Liege, Belgium
    BMC Neurol 11:25. 2011
    ..However its mode of action remains elusive. Since the long delay to meaningful effect suggests that ONS induces slow neuromodulation, we have searched for changes in central pain-control areas using metabolic neuroimaging...
  67. doi request reprint Dualism persists in the science of mind
    Athena Demertzi
    Coma Science Group, Cyclotron Research Centre, University of Liege, Liege, Belgium
    Ann N Y Acad Sci 1157:1-9. 2009
    ..We suggest that the results are relevant to clinical practice, to the formulation of scientific questions about the nature of consciousness, and to the reception of scientific theories of consciousness by the general public...
  68. ncbi request reprint Behavioral evaluation of consciousness in severe brain damage
    Steve Majerus
    Department of Cognitive Sciences, University of Liege, Belgium
    Prog Brain Res 150:397-413. 2005
    ....
  69. ncbi request reprint Brain function in the vegetative state
    Steven Laureys
    Cyclotron Research Center, Department of Neurology, CHU Sart Tilman, University of Liege, Liege, Belgium
    Acta Neurol Belg 102:177-85. 2002
    ....
  70. ncbi request reprint Eye gaze and conscious processing in severely brain-injured patients
    Camille Chatelle
    Coma Science Group, Cyclotron Research Centre, University of Liege, 4000 Liege, Belgium http www ulg ac be www coma ulg ac be
    Behav Brain Sci 33:442-3. 2010
    ..In this commentary, we illustrate the relationship between oriented eye movements, consciousness, and emotion by using the case of severely brain-injured patients recovering from coma (i.e., vegetative and minimally conscious patients)...
  71. ncbi request reprint Phonological short-term memory networks following recovery from Landau and Kleffner syndrome
    Steve Majerus
    Department of Cognitive Sciences, University of Liege, Liege, Belgium
    Hum Brain Mapp 19:133-44. 2003
    ..These data suggest that impaired verbal STM at late outcome of LKS might indeed be related to a persistent decrease of activity in those posterior superior temporal gyri that were involved in the epileptic focus during the active phase...
  72. ncbi request reprint Science and society: death, unconsciousness and the brain
    Steven Laureys
    Cyclotron Research Centre and Neurology Department, Universite de Liege, Sart Tilman B30, 4000 Liege, Belgium
    Nat Rev Neurosci 6:899-909. 2005
    ....
  73. ncbi request reprint Functional neuroimaging in the vegetative state
    Steven Laureys
    Department of Neurology and Cyclotron Research Center, University of Liege, Sart Tilman B30, 4000 Liege, Belgium
    NeuroRehabilitation 19:335-41. 2004
    ..However, this activation is limited to primary cortices and dissociated from higher-order associative cortices, thought to be necessary for conscious perception...
  74. ncbi request reprint Brain function in coma, vegetative state, and related disorders
    Steven Laureys
    Belgian National Funds for Scientific Research Cyclotron Research Center and Department of Neurology, University of Liege, Belgium
    Lancet Neurol 3:537-46. 2004
    ..Neuroimaging techniques remain important tools for clinical research that will extend our understanding of the underlying mechanisms of these disorders...
  75. ncbi request reprint Cerebral correlates of explicit sequence learning
    Arnaud Destrebecqz
    Cognitive Science Research Unit, Universite Libre de Bruxelles, Bruxelles, Belgium
    Brain Res Cogn Brain Res 16:391-8. 2003
    ..This suggests a significant role for the ACC/MPFC in the explicit processing of sequential material...
  76. ncbi request reprint Brain response to one's own name in vegetative state, minimally conscious state, and locked-in syndrome
    Fabien Perrin
    Laboratoire de Neurosciences and Systèmes Sensoriels, UMR 5020, Université Claude Bernard Lyon 1 CNRS, 50 avenue Tony Garnier, 69366 Lyon Cedex 07, France
    Arch Neurol 63:562-9. 2006
    ..A major challenge in the management of severely brain-injured patients with altered states of consciousness is to estimate their residual perception of the environment...
  77. pmc Cytology and functionally correlated circuits of human posterior cingulate areas
    Brent A Vogt
    Cingulum NeuroSciences Institute and SUNY Upstate Medical University, 750 E Adams Street, Syracuse, NY 13210, USA
    Neuroimage 29:452-66. 2006
    ....
  78. ncbi request reprint Functional neuroimaging applications for assessment and rehabilitation planning in patients with disorders of consciousness
    Joseph T Giacino
    JFK Johnson Rehabilitation Institute, and New Jersey Neuroscience Institute, JFK Medical Center, Edison, NJ 08818, USA
    Arch Phys Med Rehabil 87:S67-76. 2006
    ..To describe the theoretic framework, design, and potential clinical applications of functional neuroimaging protocols in patients with disorders of consciousness...
  79. ncbi request reprint Sleep and motor skill learning
    Steven Laureys
    Cyclotron Research Centre, University of Liege, Sart Tilman, 4000 Liege, Belgium
    Neuron 35:5-7. 2002
    ..In this issue of Neuron, provide behavioral evidence that most of the improvement of a motor skill depends on nocturnal sleep...
  80. ncbi request reprint Increased cerebral functional connectivity underlying the antinociceptive effects of hypnosis
    Marie Elisabeth Faymonville
    Department of Anesthesiology and Intensive Care Medicine, CHU Sart Tilman, University of Liege, 4000 Liege, Belgium
    Brain Res Cogn Brain Res 17:255-62. 2003
    ....
  81. ncbi request reprint Detecting awareness in the vegetative state
    Adrian M Owen
    Medical Research Council Cognition and Brain Sciences Unit, Cambridge CB2 2EF, UK
    Science 313:1402. 2006
    ..When asked to imagine playing tennis or moving around her home, the patient activated predicted cortical areas in a manner indistinguishable from that of healthy volunteers...
  82. ncbi request reprint Neural correlates of "hot" and "cold" emotional processing: a multilevel approach to the functional anatomy of emotion
    Alexandre Schaefer
    Department of Psychology, University of Louvain, Place du Cardinal Mercier 10, 1348 Louvain la Neuve, Belgium
    Neuroimage 18:938-49. 2003
    ....
  83. ncbi request reprint Be caught napping: you're doing more than resting your eyes
    Pierre Maquet
    Nat Neurosci 5:618-9. 2002
  84. ncbi request reprint Bispectral analysis of electroencephalogram signals during recovery from coma: preliminary findings
    Caroline Schnakers
    University of Liege, Liege, Belgium
    Neuropsychol Rehabil 15:381-8. 2005
    ..These preliminary findings are encouraging in the search for electrophysiological correlates of consciousness in severe acute brain damage...
  85. ncbi request reprint Eyes open, brain shut
    Steven Laureys
    Coma Research Group, Cyclotron Research Center, University of Liege, Belgium
    Sci Am 296:84-9. 2007
  86. pmc Posterior cingulate, precuneal and retrosplenial cortices: cytology and components of the neural network correlates of consciousness
    Brent A Vogt
    Cingulum NeuroSciences Institute and SUNY Upstate Medical University Syracuse, NY 13210, USA
    Prog Brain Res 150:205-17. 2005
    ....
  87. ncbi request reprint One, not two, neural correlates of consciousness
    Bernard J Baars
    Trends Cogn Sci 9:269; author reply 270. 2005
  88. pmc The neural correlates of implicit and explicit sequence learning: Interacting networks revealed by the process dissociation procedure
    Arnaud Destrebecqz
    Cognitive Science Research Unit, Universite Libre de Bruxelles, B 1050 Belgium Cyclotron Research Center, University of Liege, Switzerland
    Learn Mem 12:480-90. 2005
    ..They also supply further evidence for a partial dissociation between the neural substrates supporting conscious and nonconscious components of performance during recollection of a learned sequence...
  89. doi request reprint Brain function in physiologically, pharmacologically, and pathologically altered states of consciousness
    Pierre Boveroux
    Department of Neurology, Coma Science Group, University of Liege, Liege, Belgium
    Int Anesthesiol Clin 46:131-46. 2008
  90. ncbi request reprint Does the FOUR score correctly diagnose the vegetative and minimally conscious states?
    Caroline Schnakers
    Ann Neurol 60:744-5; author reply 745. 2006
  91. ncbi request reprint Nonvisual responses to light exposure in the human brain during the circadian night
    Fabien Perrin
    Centre de Recherches du Cyclotron B30, Universite de Liege, Sart Tilman, 4000 Liege, Belgium
    Curr Biol 14:1842-6. 2004
    ..Activity in the hypothalamus decreased in proportion to previous illumination. These findings have important implications for understanding the effects of light on human behavior...
  92. ncbi request reprint Neural mechanisms involved in the detection of our first name: a combined ERPs and PET study
    Fabien Perrin
    Centre de Recherches du Cyclotron, Universite de Liege, Belgique
    Neuropsychologia 43:12-9. 2005
    ..These results suggest that the medial prefrontal cortex plays the most prominent role in self-processing...
  93. doi request reprint A twitch of consciousness: defining the boundaries of vegetative and minimally conscious states
    Quentin Noirhomme
    J Neurol Neurosurg Psychiatry 79:741-2. 2008
  94. ncbi request reprint Brain, conscious experience and the observing self
    Bernard J Baars
    The Neurosciences Institute, San Diego, CA 92121, USA
    Trends Neurosci 26:671-5. 2003
    ..Such functions can be viewed as properties of the subject, rather than the object, of experience - the 'observing self' that appears to be needed to maintain the conscious state...
  95. ncbi request reprint Festina lente: evidences for fast and slow learning processes and a role for sleep in human motor skill learning
    Pierre Maquet
    Cyclotron Research Centre, University of Liege, Belgium
    Learn Mem 10:237-9. 2003
  96. doi request reprint Neuroimaging and disorders of consciousness: envisioning an ethical research agenda
    Joseph J Fins
    Weill Medical College of Cornell University, New York, NY 10021, USA
    Am J Bioeth 8:3-12. 2008
    ..It represents an interdisciplinary approach to the challenges posed by the emerging use of neuroimaging technologies to describe and characterize disorders of consciousness...
  97. ncbi request reprint Quantifying consciousness
    Steven Laureys
    Lancet Neurol 4:789-90. 2005
  98. ncbi request reprint The cognitive modulation of pain: hypnosis- and placebo-induced analgesia
    Ron Kupers
    Center for Functionally Integrative Neuroscience CFIN, Aarhus University and Aarhus University Hospital, Aarhus, Denmark
    Prog Brain Res 150:251-69. 2005
    ....
  99. ncbi request reprint Are we equal in death? Avoiding diagnostic error in brain death
    Steven Laureys
    Neurology 70:e14-5. 2008
  100. ncbi request reprint Using functional magnetic resonance imaging to detect covert awareness in the vegetative state
    Adrian M Owen
    Medical Research Council Cognition and Brain Sciences Unit, Cambridge, England
    Arch Neurol 64:1098-102. 2007
    ....
  101. ncbi request reprint Naloxone-insensitive epidural placebo analgesia in a chronic pain patient
    Ron Kupers
    PET Unit and Section of Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark, and Neurology Department, University of Liege, Liege, Belgium
    Anesthesiology 106:1239-42. 2007