Marc Lacroix

Summary

Country: Belgium

Publications

  1. ncbi request reprint p53 and breast cancer, an update
    Marc Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet Université Libre de Bruxelles, 127 boulevard de Waterloo, B 1000 Bruxelles, Belgium
    Endocr Relat Cancer 13:293-325. 2006
  2. ncbi request reprint The "portrait" of hereditary breast cancer
    Marc Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Universite Libre de Bruxelles, 127, boulevard de Waterloo, B 1000, Bruxelles, Belgium
    Breast Cancer Res Treat 89:297-304. 2005
  3. ncbi request reprint Stable 'portrait' of breast tumors during progression: data from biology, pathology and genetics
    M Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Universite Libre de Bruxelles, 127 boulevard de Waterloo, B 1000 Bruxelles, Brussels, Belgium
    Endocr Relat Cancer 11:497-522. 2004
  4. ncbi request reprint About GATA3, HNF3A, and XBP1, three genes co-expressed with the oestrogen receptor-alpha gene (ESR1) in breast cancer
    M Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Universite Libre de Bruxelles, 127 boulevard de Waterloo, B 1000 Bruxelles, Belgium
    Mol Cell Endocrinol 219:1-7. 2004
  5. ncbi request reprint Estrogens decrease gamma-ray-induced senescence and maintain cell cycle progression in breast cancer cells independently of p53
    Robert Alain Toillon
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Universite Libre de Bruxelles, Brussels, Belgium
    Int J Radiat Oncol Biol Phys 67:1187-200. 2007
  6. ncbi request reprint Estrogen receptor-negative/progesterone receptor-positive Evsa-T mammary tumor cells: a model for assessing the biological property of this peculiar phenotype of breast cancers
    M Borras
    Laboratoire J C Heuson de Cancérologie Mammaire, Service de Medecine, Institut Jules Bordet, Brussels, Belgium
    Cancer Lett 120:23-30. 1997
  7. ncbi request reprint Estrogen receptor alpha: impact of ligands on intracellular shuttling and turnover rate in breast cancer cells
    Guy Leclercq
    Laboratoire J C Heuson de Cancérologie Mammaire, Institut Jules Bordet, Service de Médecine Université Libre de Bruxelles, Rue Heger Bordet, 1 1000 Brussels, Belgium
    Curr Cancer Drug Targets 6:39-64. 2006
  8. ncbi request reprint Molecular characterization of breast cancer cell lines by a low-density microarray
    Francoise de Longueville
    Eppendorf Array Technologies, 5000 Namur, Belgium
    Int J Oncol 27:881-92. 2005
  9. ncbi request reprint Significance, detection and markers of disseminated breast cancer cells
    Marc Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Bruxelles, Belgium
    Endocr Relat Cancer 13:1033-67. 2006
  10. ncbi request reprint Relevance of breast cancer cell lines as models for breast tumours: an update
    Marc Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Universite Libre de Bruxelles, Bruxelles, Belgium
    Breast Cancer Res Treat 83:249-89. 2004

Collaborators

Detail Information

Publications16

  1. ncbi request reprint p53 and breast cancer, an update
    Marc Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet Université Libre de Bruxelles, 127 boulevard de Waterloo, B 1000 Bruxelles, Belgium
    Endocr Relat Cancer 13:293-325. 2006
    ..The present paper aims to provide updated information on p53 regulation and function, with specific interest on its role in breast cancer...
  2. ncbi request reprint The "portrait" of hereditary breast cancer
    Marc Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Universite Libre de Bruxelles, 127, boulevard de Waterloo, B 1000, Bruxelles, Belgium
    Breast Cancer Res Treat 89:297-304. 2005
    ..The present review aims to summarize recent data on BRCA1, BRCA2, and BRCAx HBC, including hypotheses on the origin of BRCA1 tumors and their paradoxical relations to estrogen-sensitivity...
  3. ncbi request reprint Stable 'portrait' of breast tumors during progression: data from biology, pathology and genetics
    M Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Universite Libre de Bruxelles, 127 boulevard de Waterloo, B 1000 Bruxelles, Brussels, Belgium
    Endocr Relat Cancer 11:497-522. 2004
    ..While many of the data presented here are related to ductal tumors, lobular cancer is also discussed...
  4. ncbi request reprint About GATA3, HNF3A, and XBP1, three genes co-expressed with the oestrogen receptor-alpha gene (ESR1) in breast cancer
    M Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Universite Libre de Bruxelles, 127 boulevard de Waterloo, B 1000 Bruxelles, Belgium
    Mol Cell Endocrinol 219:1-7. 2004
    ..We notably show the relations that exist, or that might exist, between these factors and the oestrogen-inducible trefoil factor TFF1...
  5. ncbi request reprint Estrogens decrease gamma-ray-induced senescence and maintain cell cycle progression in breast cancer cells independently of p53
    Robert Alain Toillon
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Universite Libre de Bruxelles, Brussels, Belgium
    Int J Radiat Oncol Biol Phys 67:1187-200. 2007
    ..Recent clinical reports suggest that radiotherapy could be more efficient in association with endocrine therapy. The aim of this study was to evaluate the estrogen effects on irradiated breast cancer cells (IR-cells)...
  6. ncbi request reprint Estrogen receptor-negative/progesterone receptor-positive Evsa-T mammary tumor cells: a model for assessing the biological property of this peculiar phenotype of breast cancers
    M Borras
    Laboratoire J C Heuson de Cancérologie Mammaire, Service de Medecine, Institut Jules Bordet, Brussels, Belgium
    Cancer Lett 120:23-30. 1997
    ..Our Evsa-T clone could be a valuable model for assessing the mechanisms leading the ER-/PR+ phenotype occurring occasionally in breast cancers and frequently in meningiomas...
  7. ncbi request reprint Estrogen receptor alpha: impact of ligands on intracellular shuttling and turnover rate in breast cancer cells
    Guy Leclercq
    Laboratoire J C Heuson de Cancérologie Mammaire, Institut Jules Bordet, Service de Médecine Université Libre de Bruxelles, Rue Heger Bordet, 1 1000 Brussels, Belgium
    Curr Cancer Drug Targets 6:39-64. 2006
    ..The present paper surveys these biological data and analyzes how they may be integrated into new drug design programs aimed at expanding our therapeutic armamentarium against breast cancer...
  8. ncbi request reprint Molecular characterization of breast cancer cell lines by a low-density microarray
    Francoise de Longueville
    Eppendorf Array Technologies, 5000 Namur, Belgium
    Int J Oncol 27:881-92. 2005
    ....
  9. ncbi request reprint Significance, detection and markers of disseminated breast cancer cells
    Marc Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Bruxelles, Belgium
    Endocr Relat Cancer 13:1033-67. 2006
    ..The significance of DTC for the prognosis and prediction of response to therapy is examined. DTC viability, the notion of cell dormancy and the concept of breast cancer stem cells are also discussed...
  10. ncbi request reprint Relevance of breast cancer cell lines as models for breast tumours: an update
    Marc Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Universite Libre de Bruxelles, Bruxelles, Belgium
    Breast Cancer Res Treat 83:249-89. 2004
    ..Investigations on additional specific lines are expected to improve our knowledge of BCC and of the dialogue that these maintain with their surrounding normal cells in vivo...
  11. ncbi request reprint Interaction between estrogen receptor alpha, ionizing radiation and (anti-) estrogens in breast cancer cells
    R A Toillon
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire Institut Jules Bordet, Universite Libre de Bruxelles, Bruxelles, Belgium
    Breast Cancer Res Treat 93:207-15. 2005
    ..CONCLUSIONS: This study may increase general comprehension of ERalpha modulation by radiotherapy and improve adjuvant therapeutic approaches based on co-administration of radiation and endocrine therapy...
  12. ncbi request reprint Gene regulation by phorbol 12-myristate 13-acetate in MCF-7 and MDA-MB-231, two breast cancer cell lines exhibiting highly different phenotypes
    M Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Free University of Brussels, Brussels, Belgium
    Oncol Rep 12:701-7. 2004
    ....
  13. ncbi request reprint Estrogenic effect of a series of bisphenol analogues on gene and protein expression in MCF-7 breast cancer cells
    Ana Rivas
    Laboratory of Medical Investigations, School of Medicine, University of Granada, Spain
    J Steroid Biochem Mol Biol 82:45-53. 2002
    ..Presence of two propyl chains at the central carbon appears to confer the greatest potency in both gene and protein expression assays...
  14. ncbi request reprint Estrogen receptor analysis in primary breast tumors by ligand-binding assay, immunocytochemical assay, and northern blot: a comparison
    M Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Universite Libre de Bruxelles, Brussels, Belgium
    Breast Cancer Res Treat 67:263-71. 2001
    ....
  15. ncbi request reprint A low-density DNA microarray for analysis of markers in breast cancer
    M Lacroix
    Laboratoire Jean Claude Heuson de Cancérologie Mammaire, Institut Jules Bordet, Universite Libre de Bruxelles, Belgium
    Int J Biol Markers 17:5-23. 2002
    ..We provide a list of about 250 of these markers. We also examine some potential difficulties (homologies between marker and/or variant sequences, size of sequences, etc.) associated with the production of such a low-cost microarray...
  16. ncbi request reprint Interleukins-6 and -11 expression in primary breast cancer and subsequent development of bone metastases
    C Sotiriou
    Laboratory of Endocrinology/Bone Metabolism and Breast Cancer Research, Institut Jules Bordet, boulevard de Waterloo, 127B-1000, Brussels, Belgium
    Cancer Lett 169:87-95. 2001
    ..Our findings demonstrate for the first time IL-11 gene expression in some primary invasive breast tumors and suggest the potential of this cytokine as possible biological predictive factor for the development of bone metastases...