Rene Westhovens

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. ncbi request reprint Development of sarcoidosis in etanercept-treated rheumatoid arthritis patients
    Kilian Verschueren
    Department of Rheumatology, University Hospitals Leuven, Katholieke Universiteit Leuven, Leuven, Belgium
    Clin Rheumatol 26:1969-71. 2007
  2. ncbi request reprint Adolescents with juvenile idiopathic arthritis: who cares after the age of 16?
    D Hilderson
    Center for Health Services and Nursing Research, Katholieke Universiteit Leuven, Leuven, Belgium
    Clin Exp Rheumatol 28:790-7. 2010
  3. ncbi request reprint Long-term safety and efficacy of abatacept in patients with rheumatoid arthritis and an inadequate response to methotrexate: a 7-year extended study
    Rene Westhovens
    Department of Development and Regeneration, Neuro musculo skeletal Research Unit, KU Leuven, Belgium
    Clin Exp Rheumatol 32:553-62. 2014
  4. ncbi request reprint The early clinical course of infliximab treatment in rheumatoid arthritis: results from the REMARK observational study
    R Westhovens
    Skeletal Biology and Engineering Research Center, Department of Development and Regeneration KU Leuven Rheumatology, University Hospitals Leuven, Belgium
    Clin Exp Rheumatol 32:315-23. 2014
  5. pmc The impact of infliximab treatment on quality of life in patients with inflammatory rheumatic diseases
    Chenglong Han
    Centocor Research and Development, Inc, 200 Great Valley Parkway, Malvern, Pennsylvania 19355, USA
    Arthritis Res Ther 9:R103. 2007
  6. pmc Response to the commentary 'Pooled indices to measure rheumatoid arthritis activity: a good reflection of the physician's mind'
    Bert Vander Cruyssen
    Arthritis Res Ther 8:406. 2006
  7. pmc The ITGAV rs3738919-C allele is associated with rheumatoid arthritis in the European Caucasian population: a family-based study
    Laurent Jacq
    GenHotel EA3886, Evry Paris VII Universities, 91057 Evry Genopole Cedex, France
    Arthritis Res Ther 9:R63. 2007
  8. pmc Clinical and serological evaluation of a novel CENP-A peptide based ELISA
    Michael Mahler
    Dr Fooke Laboratorien, Mainstrasse 85, 41469 Neuss, Germany
    Arthritis Res Ther 12:R99. 2010
  9. pmc Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors
    R Westhovens
    UZ Gasthuisberg, Department of Rheumatology, B 3000 Leuven, Belgium
    Ann Rheum Dis 68:1870-7. 2009
  10. ncbi request reprint Improved health-related quality of life for rheumatoid arthritis patients treated with abatacept who have inadequate response to anti-TNF therapy in a double-blind, placebo-controlled, multicentre randomized clinical trial
    R Westhovens
    UZ KU LeuvenDienst Reumatologie, Herestraat 49B 3000, Leuven, Belgium
    Rheumatology (Oxford) 45:1238-46. 2006

Detail Information

Publications63

  1. ncbi request reprint Development of sarcoidosis in etanercept-treated rheumatoid arthritis patients
    Kilian Verschueren
    Department of Rheumatology, University Hospitals Leuven, Katholieke Universiteit Leuven, Leuven, Belgium
    Clin Rheumatol 26:1969-71. 2007
    ..In our cases, the temporal association with etanercept therapy and the complete remission after suspension of etanercept suggest a triggering role of this agent. Possible mechanisms of action and supporting evidence are discussed...
  2. ncbi request reprint Adolescents with juvenile idiopathic arthritis: who cares after the age of 16?
    D Hilderson
    Center for Health Services and Nursing Research, Katholieke Universiteit Leuven, Leuven, Belgium
    Clin Exp Rheumatol 28:790-7. 2010
    ..The aims of this study were 1) to identify the settings in which JIA patients are followed up after leaving paediatric rheumatology, and 2) to compare the clinical profile of patients in different settings...
  3. ncbi request reprint Long-term safety and efficacy of abatacept in patients with rheumatoid arthritis and an inadequate response to methotrexate: a 7-year extended study
    Rene Westhovens
    Department of Development and Regeneration, Neuro musculo skeletal Research Unit, KU Leuven, Belgium
    Clin Exp Rheumatol 32:553-62. 2014
    ..To assess the safety and efficacy of intravenous (IV) abatacept plus methotrexate (MTX) over 7 years, the longest observational period to date, in patients with established rheumatoid arthritis (RA) and an inadequate response to MTX...
  4. ncbi request reprint The early clinical course of infliximab treatment in rheumatoid arthritis: results from the REMARK observational study
    R Westhovens
    Skeletal Biology and Engineering Research Center, Department of Development and Regeneration KU Leuven Rheumatology, University Hospitals Leuven, Belgium
    Clin Exp Rheumatol 32:315-23. 2014
    ..We aimed to describe patterns of disease activity during infliximab plus methotrexate (MTX) treatment and explore C-reactive protein (CRP) as a potential marker of early response...
  5. pmc The impact of infliximab treatment on quality of life in patients with inflammatory rheumatic diseases
    Chenglong Han
    Centocor Research and Development, Inc, 200 Great Valley Parkway, Malvern, Pennsylvania 19355, USA
    Arthritis Res Ther 9:R103. 2007
    ..Patients in large randomized controlled studies of infliximab in RA, PsA, and AS had similar impairment in physical aspects of HRQoL at baseline and showed significantly greater improvement in HRQoL after treatment with infliximab...
  6. pmc Response to the commentary 'Pooled indices to measure rheumatoid arthritis activity: a good reflection of the physician's mind'
    Bert Vander Cruyssen
    Arthritis Res Ther 8:406. 2006
  7. pmc The ITGAV rs3738919-C allele is associated with rheumatoid arthritis in the European Caucasian population: a family-based study
    Laurent Jacq
    GenHotel EA3886, Evry Paris VII Universities, 91057 Evry Genopole Cedex, France
    Arthritis Res Ther 9:R63. 2007
    ..002, odds ratio = 1.94, 95% confidence interval = 1.3-2.9). The rs3738919-C allele of the ITGAV gene is associated with RA in the European Caucasian population, suggesting ITGAV as a new minor RA susceptibility gene...
  8. pmc Clinical and serological evaluation of a novel CENP-A peptide based ELISA
    Michael Mahler
    Dr Fooke Laboratorien, Mainstrasse 85, 41469 Neuss, Germany
    Arthritis Res Ther 12:R99. 2010
    ..Historically, ACA were detected by indirect immunofluorescence (IIF) on HEp-2 cells and confirmed by immunoassays using recombinant CENP-B. The objective of this study was to evaluate a novel CENP-A peptide ELISA...
  9. pmc Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors
    R Westhovens
    UZ Gasthuisberg, Department of Rheumatology, B 3000 Leuven, Belgium
    Ann Rheum Dis 68:1870-7. 2009
    ..To assess the efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis (RA) and poor prognostic factors...
  10. ncbi request reprint Improved health-related quality of life for rheumatoid arthritis patients treated with abatacept who have inadequate response to anti-TNF therapy in a double-blind, placebo-controlled, multicentre randomized clinical trial
    R Westhovens
    UZ KU LeuvenDienst Reumatologie, Herestraat 49B 3000, Leuven, Belgium
    Rheumatology (Oxford) 45:1238-46. 2006
    ..The current study sought to demonstrate the efficacy of abatacept on quality of life (QoL) for RA patients with inadequate response to anti-TNF therapy...
  11. ncbi request reprint Safety and efficacy of the selective costimulation modulator abatacept in patients with rheumatoid arthritis receiving background methotrexate: a 5-year extended phase IIB study
    Rene Westhovens
    Department of Rheumatology, KU Leuven, Herestraat 49, B 3000 Leuven, Belgium
    J Rheumatol 36:736-42. 2009
    ..To evaluate the safety and efficacy of abatacept plus methotrexate (MTX) over 5 years in patients with rheumatoid arthritis...
  12. ncbi request reprint The safety of infliximab, combined with background treatments, among patients with rheumatoid arthritis and various comorbidities: a large, randomized, placebo-controlled trial
    Rene Westhovens
    UZ Gasthuisberg, Leuven, Belgium
    Arthritis Rheum 54:1075-86. 2006
    ....
  13. ncbi request reprint Healthcare consumption and direct costs of rheumatoid arthritis in Belgium
    R Westhovens
    Department of Rheumatology, University Hospitals KU Leuven, Belgium
    Clin Rheumatol 24:615-9. 2005
    ..Differences in healthcare consumption between patients could be mainly explained by differences in physical function (HAQ)...
  14. pmc Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity
    Bert Vander Cruyssen
    Department of Rheumatology, Ghent University Hospital, B 9000 Gent, Belgium
    Arthritis Res Ther 8:R112. 2006
    ..Disease activity measured by the DAS28 at week 14 or 22 of infliximab therapy was the best predictor of long-term attrition...
  15. pmc Seven-year follow-up of infliximab therapy in rheumatoid arthritis patients with severe long-standing refractory disease: attrition rate and evolution of disease activity
    Bert Vander Cruyssen
    Department of Rheumatology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Arthritis Res Ther 12:R77. 2010
    ..The objectives of this study were to evaluate the continuation rate of infliximab and its clinical effect over a 7-year period and to document the reasons for discontinuation...
  16. doi request reprint Prospective study to assess short-term intra-articular and tenosynovial changes in the aromatase inhibitor-associated arthralgia syndrome
    Leilani Morales
    Department of Obstetrics and Gynecology, Division of Gynecological Oncology, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
    J Clin Oncol 26:3147-52. 2008
    ..To date, its exact mechanism remains unclear. The purpose of this study was to investigate the changes in clinical rheumatologic features and magnetic resonance imaging (MRI) of hands and wrists in AI and tamoxifen users...
  17. doi request reprint Detection of antinuclear antibodies by automated indirect immunofluorescence analysis
    Xavier Bossuyt
    Experimental Laboratory Immunology, Catholic University Leuven, Leuven, Belgium
    Clin Chim Acta 415:101-6. 2013
    ..Automated systems for image acquisition and interpretation of indirect immunofluorescence-based tests are increasingly used. The diagnostic performance of such automated approach in untreated patients has not been reported...
  18. doi request reprint Transfer from paediatric rheumatology to the adult rheumatology setting: experiences and expectations of young adults with juvenile idiopathic arthritis
    Deborah Hilderson
    Department of Paediatrics, University Hospitals Leuven, Leuven, Belgium
    Clin Rheumatol 32:575-83. 2013
    ..Since we included patients who were in follow-up at one tertiary care centre, in which both paediatric and adult rheumatology care are located, the results of the study cannot be generalised to the entire population of patients with JIA...
  19. doi request reprint Heterogeneous nuclear RNPs as targets of autoantibodies in systemic rheumatic diseases
    Katrijn Op De Beéck
    Catholic University of Leuven, and Experimental Laboratory of Medicine, Immunology, University Hospitals Leuven, Leuven, Belgium
    Arthritis Rheum 64:213-21. 2012
    ..To investigate the abundance of autoantibodies to heterogeneous nuclear RNPs (hnRNPs) in systemic rheumatic diseases...
  20. doi request reprint Optimal care for early RA patients: the challenge of translating scientific data into clinical practice
    Patrick Verschueren
    Department of Rheumatology, University Hospital Leuven, Herestraat 49, B 3000 Leuven, Belgium
    Rheumatology (Oxford) 50:1194-200. 2011
    ..Given the long-term benefits of rapid disease control, health authorities should consider investing in a better implementation of intensive treatment regimens based on combinations of classical DMARDs and glucocorticoids...
  21. doi request reprint Oral administration of GLPG0259, an inhibitor of MAPKAPK5, a new target for the treatment of rheumatoid arthritis: a phase II, randomised, double-blind, placebo-controlled, multicentre trial
    Rene Westhovens
    Department of Rheumatology, University Hospital KU Leuven, Leuven, Belgium
    Ann Rheum Dis 72:741-4. 2013
    ..Mitogen-activated protein (MAP) kinases are key regulators of cytokine production, and are therefore potential targets for treatment of rheumatoid arthritis (RA)...
  22. doi request reprint Antinuclear antibody detection by automated multiplex immunoassay in untreated patients at the time of diagnosis
    Katrijn Op De Beéck
    Experimental Laboratory Immunology, Catholic University Leuven, Leuven, Belgium
    Autoimmun Rev 12:137-43. 2012
    ..7% of CFS and diseased controls, and none of the blood donors. In conclusion, test result specific likelihood ratios and the presence of multiple autoantibodies help with the interpretation of data generated by multiplex immunoassays...
  23. doi request reprint The Belgian Systemic Sclerosis Cohort: correlations between disease severity scores, cutaneous subsets, and autoantibody profile
    Marie Vanthuyne
    Rheumatology and Internal Medicine Departments, Cliniques Universitaires Saint Luc, and Centre Hospitalier Universitaire Mont Godinne, Universite Catholique de Louvain, Brussels, Belgium
    J Rheumatol 39:2127-33. 2012
    ..To report baseline and followup data on the first 438 patients with systemic sclerosis (SSc) included in the Belgian Systemic Sclerosis Cohort...
  24. pmc DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment
    Bert Vander Cruyssen
    Department of Rheumatology, Ghent University Hospital, Belgium
    Arthritis Res Ther 7:R1063-71. 2005
    ..We proved that the momentary DAS28 score correlates best with this decision and demonstrated the robustness of the score and the coefficients of the DAS28 in a cohort of RA patients under infliximab therapy...
  25. doi request reprint Belgian rheumatologists' perception on eligibility of RA patients for anti-TNF treatment matches more closely Dutch rather than Belgian reimbursement criteria
    Elke Geens
    Department of Rheumatology, University Hospitals Leuven, Leuven, Belgium
    Rheumatology (Oxford) 48:546-50. 2009
    ..To assess discrepancies between perception of Belgian rheumatologists on eligibility of RA patients for anti-TNF treatment and Belgian reimbursement criteria and to compare Belgian with Dutch criteria and UK guidelines...
  26. pmc Translating co-stimulation blockade into clinical practice
    Rene Westhovens
    Department of Rheumatology, University Hospitals KU Leuven, Herestraat, B 3000 Leuven, Belgium
    Arthritis Res Ther 10:S4. 2008
    ..It is clear, however, that every additional targeted therapy creates new opportunities for treatment in many different patient populations...
  27. ncbi request reprint Effectiveness of an integrated outpatient care programme compared with present-day standard care in early rheumatoid arthritis
    Greet Esselens
    Department of Rheumatology, University Hospital Leuven, Belgium
    Musculoskeletal Care 7:1-16. 2009
    ..To investigate the effectiveness of an integrated care programme in daily practice compared with present-day standard care for ambulatory early rheumatoid arthritis patients...
  28. doi request reprint Effectiveness of initial treatment allocation based on expert opinion for prevention of rapid radiographic progression in daily practice of an early RA cohort
    Anne Durnez
    Department of Rheumatology, University Hospital Leuven, Herestraat 49, B 3000 Leuven, Belgium
    Ann Rheum Dis 70:634-7. 2011
    ..To evaluate expert treatment selection for early rheumatoid arthritis and to validate a prediction model for rapid radiographic progression (RRP) in daily practice...
  29. doi request reprint Attitudes of rheumatology practitioners toward transition and transfer from pediatric to adult healthcare
    Deborah Hilderson
    Center for Health Services and Nursing Research, Katholieke Universiteit Leuven, Kapucijnenvoer 35, Box 7001, 3000 Leuven, Belgium
    Rheumatol Int 32:3887-96. 2012
    ..In conclusion, this study emphasized the importance of transfer to specialized rheumatology care of adolescents with an active rheumatic disease and highlighted transfer initiators and transfer communication tools...
  30. pmc The Belgian MIRA (MabThera In Rheumatoid Arthritis) registry: clues for the optimization of rituximab treatment strategies
    Bert Vander Cruyssen
    Department of Rheumatology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Arthritis Res Ther 12:R169. 2010
    ....
  31. doi request reprint Unusual cervical spine involvement in psoriatic arthritis: a case series
    Inge Van Tilt
    Division of Rheumatology, Department of Musculoskeletal Sciences, University Hospitals Leuven, KU Leuven, Herestraat 49, Leuven 3000, Belgium
    Clin Rheumatol 28:1343-6. 2009
    ..These cases therefore illustrate different aspects of the involvement of the cervical spine in axial forms of psoriatic arthritis and highlight the importance of proper evaluation and management of axial disease in psoriatic arthritis...
  32. ncbi request reprint Detection of anti-SSA antibodies by indirect immunofluorescence
    Xavier Bossuyt
    Laboratory Medicine and Internal Medicine, University Hospital Leuven, Leuven, Belgium
    Clin Chem 50:2361-9. 2004
    ..We describe a survey on the detection of anti-SSA antibodies using a commercial substrate that overexpresses SSA...
  33. ncbi request reprint Victimization in chronic fatigue syndrome and fibromyalgia in tertiary care: a controlled study on prevalence and characteristics
    B Van Houdenhove
    Department of Psychosomatic Rehabilitation, Katholieke Universiteit Leuven, Belgium
    Psychosomatics 42:21-8. 2001
    ..These findings support etiological hypotheses suggesting a pivotal role for chronic stress in CFS and FM and may have important therapeutic implications...
  34. ncbi request reprint Rheumatic disorders and glucocorticoid-induced osteoporosis
    J Dequeker
    Department of Rheumatology, University Hospitals, KU Leuven, Belgium
    Front Horm Res 30:107-20. 2002
  35. pmc A prospective randomised multicentre study comparing continuous and intermittent treatment with celecoxib in patients with osteoarthritis of the knee or hip
    F P Luyten
    Department of Rheumatology, University Hospitals KULeuven, Herestraat 49, B3000 Leuven, Belgium
    Ann Rheum Dis 66:99-106. 2007
    ..To compare the effects of continuous and intermittent celecoxib treatment in patients with knee or hip osteoarthritis in flare...
  36. ncbi request reprint Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide
    P Verschueren
    Department of Rheumatology, University Hospital Leuven, Belgium
    Clin Rheumatol 24:87-90. 2005
    ..Given the long half-life of this drug a washout procedure with cholestyramine should be considered whenever the problem is severe or persistent...
  37. ncbi request reprint Daily practice effectiveness of a step-down treatment in comparison with a tight step-up for early rheumatoid arthritis
    P Verschueren
    Department of Rheumatology, University Hospitals Leuven, Herestraat 49, B 3000 Leuven, Belgium
    Rheumatology (Oxford) 47:59-64. 2008
    ..To study prospectively the daily practice effectiveness of a step-down early rheumatoid arthritis (RA) treatment strategy...
  38. doi request reprint Predictors of remission, normalized physical function, and changes in the working situation during follow-up of patients with early rheumatoid arthritis: an observational study
    P Verschueren
    Department of Rheumatology, University Hospitals, Leuven, Belgium
    Scand J Rheumatol 38:166-72. 2009
    ..To evaluate possible predictors of remission, normalized physical function, and work change in rheumatoid arthritis (RA)...
  39. ncbi request reprint Anti-TNF therapy and malignancy in spondyloarthritis in the Leuven spondyloarthritis biologics cohort (BIOSPAR)
    Ine Westhovens
    Skeletal Biology and Engineering Research Center, Department of Development and Regeneration KU Leuven Rheumatology, University Hospitals Leuven, Belgium
    Clin Exp Rheumatol 32:71-6. 2014
    ....
  40. ncbi request reprint Educational issues in rheumatology. The musculoskeletal examination: a neglected skill
    Jan Dequeker
    Department of Rheumatology, University Hospitals K U Leuven, Leuven, Belgium
    Clin Rheumatol 26:5-7. 2007
  41. doi request reprint The association of illness perceptions with physical and mental health in systemic sclerosis patients: an exploratory study
    Seher Arat
    Department of Rheumatology, University Hospitals Leuven, KU Leuven, Belgium
    Musculoskeletal Care 10:18-28. 2012
    ..The aim of the present study was to evaluate the association between illness perceptions and the ability to cope with physical and mental health problems in a large cohort of systemic sclerosis (SSc) patients...
  42. pmc Destructive dural ectasia of dorsal and lumbar spine with cauda equina syndrome in a patient with ankylosing spondylitis
    Marijke Van Hoydonck
    Division of Rheumatology, University Hospitals Leuven, Herestraat 49, B 3000, Leuven, Belgium
    Open Rheumatol J 4:31-4. 2010
    ....
  43. doi request reprint Heterogeneous nuclear ribonucleoprotein h1, a novel nuclear autoantigen
    Karolien Van den Bergh
    Laboratory Medicine, Immunology, University Hospitals Leuven, Leuven, Belgium
    Clin Chem 55:946-54. 2009
    ....
  44. doi request reprint Detection, identification and in vivo treatment responsiveness of bone morphogenetic protein (BMP)-activated cell populations in the synovium of patients with rheumatoid arthritis
    P C P M Verschueren
    Laboratory for Skeletal Development and Joint Disorders, Division of Rheumatology Department of Musculoskeletal Sciences, Katholieke Universiteit Leuven, Belgium
    Ann Rheum Dis 68:117-23. 2009
    ..To characterise the bone morphogenetic protein (BMP) target cells positive for phosphorylated (P)-SMAD1/5, in rheumatoid arthritis (RA) synovium...
  45. ncbi request reprint A dose adjustment in patients with rheumatoid arthritis not optimally responding to a standard dose of infliximab of 3 mg/kg every 8 weeks can be effective: a Belgian prospective study
    P Durez
    Rheumatology Department, UZ Gasthuisberg, Katholieke Universiteit Leuven, Belgium
    Rheumatology (Oxford) 44:465-8. 2005
    ..To analyse the effect of a dose increase in patients with severe rheumatoid arthritis (RA) with insufficient clinical response to 3 mg/kg infliximab every 8 weeks...
  46. ncbi request reprint Ten-year followup of infliximab therapy in rheumatoid arthritis patients with severe, longstanding refractory disease: a cohort study
    Filip De Keyser
    From Department of Rheumatology, Ghent University, Ghent MSD Belgium BVBA Department of Rheumatology, Pôle de recherche en Rhumatologie, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain and Cliniques Universitaires Saint Luc, Brussels Skeletal Biology and Engineering Research Center, Department of Development and Regeneration KU Leuven and Department of Rheumatology, University Hospitals Leuven, Leuven, Belgium F De Keyser, MD J De Kock, MD, Department of Rheumatology, Ghent University H Leroi, MSD Belgium BVBA, Brussels P Durez, MD, Department of Rheumatology, Pôle de recherche en Rhumatologie, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain and Cliniques Universitaires Saint Luc R Westhovens, MD, PhD, Skeletal Biology and Engineering Research Center, Department of Development and Regeneration KU Leuven and Department of Rheumatology, University Hospitals Leuven
    J Rheumatol 41:1276-81. 2014
    ..The objectives of the study were to evaluate the continuation rate, reasons for discontinuation, and longterm disease control under IFX treatment, and to study baseline characteristics associated with longterm successful IFX therapy...
  47. ncbi request reprint Clinical relevance of measurement of antibodies to individual snU1-RNP proteins
    Ariane Luyckx
    Laboratory Medicine, University Hospital Leuven, Leuven, Belgium
    Clin Chem 51:1888-90. 2005
  48. doi request reprint Hip involvement in ankylosing spondylitis: epidemiology and risk factors associated with hip replacement surgery
    Bert Vander Cruyssen
    Department of Rheumatology, Ghent University Hospital, B 9000 Gent, Belgium
    Rheumatology (Oxford) 49:73-81. 2010
    ..We aimed to describe the epidemiology of clinical and radiological hip involvement and define the risk factors for the hip replacement surgery in AS patients...
  49. pmc Diagnostic characteristics of a gelatin based Waaler-Rose assay (Serodia-RA) for the detection of rheumatoid factor
    T Spiritus
    Department of Laboratory Medicine, University Hospitals Leuven, Belgium
    Ann Rheum Dis 63:1169-71. 2004
    ..To evaluate the diagnostic usefulness of a gelatin based Waaler Rose assay (Serodia-RA) for the detection of rheumatoid factor (RF) in rheumatoid arthritis (RA)...
  50. pmc Physical activity assessment in patients with axial spondyloarthritis compared to healthy controls: a technology-based approach
    Thijs Willem Swinnen
    Rheumatology, University Hospitals Leuven, Leuven, Belgium Department of Development and Regeneration, KU Leuven, Leuven, Belgium Department of Rehabilitation Sciences, KU Leuven, Heverlee, Belgium
    PLoS ONE 9:e85309. 2014
    ....
  51. ncbi request reprint Are personal characteristics associated with exercise participation in patients with rheumatoid arthritis? A cross-sectional explorative survey
    Nele Vervloesem
    Department of Rheumatology, University Hospital Leuven, Leuven, Belgium
    Musculoskeletal Care 10:90-100. 2012
    ..However, participation and adherence rates of these programs are low. This study aimed to identify demographic, personal and disease-related factors interfering with implementing an exercise program for RA...
  52. pmc The efficacy and safety of abatacept in rheumatoid arthritis
    Rene Westhovens
    Division of Rheumatology, Department of Musculoskeletal Sciences, UZ KULeuven, Herestraat 49, B 3000 Leuven, Belgium
    Ther Adv Musculoskelet Dis 2:89-94. 2010
    ..In the meantime detailed analysis of all trials with a drug such as abatacept provides important information for the practicing rheumatologist...
  53. ncbi request reprint Debilitating musculoskeletal pain and stiffness with letrozole and exemestane: associated tenosynovial changes on magnetic resonance imaging
    Leilani Morales
    Department of General Medical Oncology, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium
    Breast Cancer Res Treat 104:87-91. 2007
    ..However, the pathogenesis and anatomic correlate of musculoskeletal pains have not been thoroughly evaluated. Moreover, the impact of AI-induced musculoskeletal symptoms on normal daily functioning needs to be further explored...
  54. doi request reprint What does it mean to grow up with juvenile idiopathic arthritis? A qualitative study on the perspectives of patients
    Leen Eyckmans
    Department of Paediatrics, University Hospitals Leuven, Leuven, Belgium
    Clin Rheumatol 30:459-65. 2011
    ....
  55. doi request reprint AA amyloidosis due to chronic oxalate arthritis and vasculitis in a patient with secondary oxalosis after jejunoileal bypass surgery
    Tom Cornelis
    Department of Nephrology and Renal Transplantation, University Hospitals Leuven, B 3000 Leuven, Belgium
    Nephrol Dial Transplant 23:3362-4. 2008
    ..Since no other cause of chronic inflammation could be identified, it was concluded that the amyloidosis was secondary to oxalate arthritis and vasculitis. To our knowledge, this is the first report on this association...
  56. ncbi request reprint Contemporary concepts of inflammation, damage and repair in rheumatic diseases
    Frank P Luyten
    University Hospitals Leuven, Division of Rheumatology, Herestraat 49, B 3000 Leuven, Belgium
    Best Pract Res Clin Rheumatol 20:829-48. 2006
    ..Understanding the molecular networks of joint homeostasis, repair and remodelling will be required to achieve this goal. Defining and validating clinical outcomes evaluating remission remain a challenge...
  57. ncbi request reprint Niemann-Pick disease type B: an unusual clinical presentation with multiple vertebral fractures
    P Volders
    Department of Rheumatology, University Hospitals Leuven, Herestraat, Belgium
    Am J Med Genet 109:42-51. 2002
    ..No new fractures have occurred, but the interstitial lung disease has progressed...
  58. ncbi request reprint Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig
    Joel M Kremer
    Center for Rheumatology, Albany, NY 12206, USA
    N Engl J Med 349:1907-15. 2003
    ..CTLA4Ig binds to CD80 and CD86 on antigen-presenting cells, blocking the engagement of CD28 on T cells and preventing T-cell activation. A preliminary study showed that CTLA4Ig may be effective for the treatment of rheumatoid arthritis...
  59. ncbi request reprint Decreased external home help use with improved clinical status in rheumatoid arthritis: an exploratory analysis of the Abatacept in Inadequate responders to Methotrexate (AIM) trial
    Tracy Li
    Global Epidemiology and Outcomes Research, Bristol Myers Squibb, Princeton, New Jersey, USA
    Clin Ther 30:734-48. 2008
    ....
  60. ncbi request reprint Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: a randomized trial
    Joel M Kremer
    Center for Rheumatology, Albany, New York, USA
    Ann Intern Med 144:865-76. 2006
    ..The selective co-stimulation modulator abatacept demonstrated efficacy for treating rheumatoid arthritis in early clinical studies...
  61. pmc Double-blinded infliximab dose escalation in patients with rheumatoid arthritis
    Mahboob U Rahman
    Centocor Research and Development, Inc, Malvern, PA, USA
    Ann Rheum Dis 66:1233-8. 2007
    ....
  62. ncbi request reprint COBRA combination therapy in patients with early rheumatoid arthritis: long-term structural benefits of a brief intervention
    Robert B M Landewe
    Department of Internal Medicine Rheumatology, PO Box 5800, University Hospital Maastricht, 6202 AZ Maastricht, The Netherlands
    Arthritis Rheum 46:347-56. 2002
    ..The current study was conducted to investigate whether the benefits of COBRA therapy were sustained over time, and to determine which baseline factors could predict outcome...
  63. ncbi request reprint Reversible posterior leucoencephalopathy during oral treatment with methotrexate
    Dimitri Renard
    J Neurol 251:226-8. 2004