S Wera

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. ncbi request reprint Phosphoinositides in yeast: genetically tractable signalling
    S Wera
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kasteelpark Arenberg 31, B 3001 Leuven Heverlee, Flanders, Belgium
    FEMS Yeast Res 1:9-13. 2001
  2. pmc Opposite roles of trehalase activity in heat-shock recovery and heat-shock survival in Saccharomyces cerevisiae
    S Wera
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kardinaal Mercierlaan 92, B 3001 Leuven Heverlee, Flanders, Belgium
    Biochem J 343:621-6. 1999
  3. ncbi request reprint An EXCEL-based method to search for potential Ser/Thr-phosphorylation sites in proteins
    S Wera
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Leuven Heverlee, Belgium
    Comput Methods Programs Biomed 58:65-8. 1999
  4. ncbi request reprint Glucose exerts opposite effects on mRNA versus protein and activity levels of Pde1, the low-affinity cAMP phosphodiesterase from budding yeast, Saccharomyces cerevisiae
    S Wera
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Leuven Heverlee, Belgium
    FEBS Lett 420:147-50. 1997
  5. ncbi request reprint NIPP-1, a nuclear inhibitory subunit of protein phosphatase-1, has RNA-binding properties
    I Jagiello
    Afdeling Biochemie, Faculteit Geneeskunde, Katholieke Universiteit Leuven, B 3000 Leuven, Belgium
    J Biol Chem 272:22067-71. 1997
  6. pmc The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signaling
    P Ma
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, B 3001 Leuven Heverlee, Flanders, Belgium
    Mol Biol Cell 10:91-104. 1999
  7. pmc Analysis and modification of trehalose 6-phosphate levels in the yeast Saccharomyces cerevisiae with the use of Bacillus subtilis phosphotrehalase
    C van Vaeck
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kardinaal Mercierlaan 92, B-3001 Leuven-Heverlee, Flanders, Belgium
    Biochem J 353:157-162. 2001
  8. ncbi request reprint Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex
    W Bell
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kardinaal Mercierlaan 92, B 3001 Leuven Heverlee, Flanders, Belgium
    J Biol Chem 273:33311-9. 1998
  9. pmc PtdIns(4,5)P(2) and phospholipase C-independent Ins(1,4,5)P(3) signals induced by a nitrogen source in nitrogen-starved yeast cells
    J C Bergsma
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kasteelpark Arenberg 31, B-3001 Leuven-Heverlee, Flanders, Belgium
    Biochem J 359:517-23. 2001
  10. ncbi request reprint Molecular cloning of NIPP-1, a nuclear inhibitor of protein phosphatase-1, reveals homology with polypeptides involved in RNA processing
    A Van Eynde
    Afdeling Biochemie, Faculteit Geneeskunde, Katholieke Universiteit Leuven, Belgium
    J Biol Chem 270:28068-74. 1995

Collaborators

  • J M Thevelein
  • M Bollen
  • W Sun
  • A Reinders
  • J C Bergsma
  • C van Vaeck
  • P Van Dijck
  • P Ma
  • W Bell
  • I Jagiello
  • M Beullens
  • W Stalmans
  • M C Donaton
  • J H de Winde
  • N N Kasri
  • R Tisi
  • E Martegani
  • V De Wever
  • A Van Eynde
  • S Hohmann
  • C De Virgilio
  • A Wiemken
  • V Vulsteke
  • A von Gabain
  • B Sohlberg
  • S Torrekens
  • F Van Leuven

Detail Information

Publications10

  1. ncbi request reprint Phosphoinositides in yeast: genetically tractable signalling
    S Wera
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kasteelpark Arenberg 31, B 3001 Leuven Heverlee, Flanders, Belgium
    FEMS Yeast Res 1:9-13. 2001
    ..g. the absence of PtdIns(3,4,5)P(3)), this model organism is at the forefront of phosphoinositide research. In this review we will focus on recent discoveries concerning the role of phosphoinositides in yeast...
  2. pmc Opposite roles of trehalase activity in heat-shock recovery and heat-shock survival in Saccharomyces cerevisiae
    S Wera
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kardinaal Mercierlaan 92, B 3001 Leuven Heverlee, Flanders, Belgium
    Biochem J 343:621-6. 1999
    ..This suggests that trehalose breakdown is required for efficient recovery from heat shock, and that the presence of trehalase protein alone is not sufficient for efficient heat-stress recovery...
  3. ncbi request reprint An EXCEL-based method to search for potential Ser/Thr-phosphorylation sites in proteins
    S Wera
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Leuven Heverlee, Belgium
    Comput Methods Programs Biomed 58:65-8. 1999
    ..The program can easily be updated in case new recognition sites are described. With a few adaptations, the tool can also be used to find other patterns in a protein sequence...
  4. ncbi request reprint Glucose exerts opposite effects on mRNA versus protein and activity levels of Pde1, the low-affinity cAMP phosphodiesterase from budding yeast, Saccharomyces cerevisiae
    S Wera
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Leuven Heverlee, Belgium
    FEBS Lett 420:147-50. 1997
    ..Hence, glucose addition appears to trigger an increase in PDE1 gene transcription together with a specific inhibition of the translation of Pde1 mRNA...
  5. ncbi request reprint NIPP-1, a nuclear inhibitory subunit of protein phosphatase-1, has RNA-binding properties
    I Jagiello
    Afdeling Biochemie, Faculteit Geneeskunde, Katholieke Universiteit Leuven, B 3000 Leuven, Belgium
    J Biol Chem 272:22067-71. 1997
    ..The catalytic subunit of protein phosphatase-1 did not bind to poly(U)-Sepharose, but it bound very tightly after complexation with NIPP-1. These data are in agreement with a function of NIPP-1 in targeting protein phosphatase-1 to RNA...
  6. pmc The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signaling
    P Ma
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, B 3001 Leuven Heverlee, Flanders, Belgium
    Mol Biol Cell 10:91-104. 1999
    ..The PKA recognition site is conserved in the corresponding region of the Schizosaccharomyces pombe and Candida albicans Pde1 homologues, possibly indicating a similar control by phosphorylation...
  7. pmc Analysis and modification of trehalose 6-phosphate levels in the yeast Saccharomyces cerevisiae with the use of Bacillus subtilis phosphotrehalase
    C van Vaeck
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kardinaal Mercierlaan 92, B-3001 Leuven-Heverlee, Flanders, Belgium
    Biochem J 353:157-162. 2001
    ..Taken together, our results support a model in which the regulatory function of Tps1 on sugar influx is mediated both by the Tps1 protein and by Tre6P...
  8. ncbi request reprint Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex
    W Bell
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kardinaal Mercierlaan 92, B 3001 Leuven Heverlee, Flanders, Belgium
    J Biol Chem 273:33311-9. 1998
    ..We discuss the possible role of differentially regulated Tps1 in a complex-bound or monomeric form in light of the requirement of Tps1 for trehalose production and for growth on glucose and fructose...
  9. pmc PtdIns(4,5)P(2) and phospholipase C-independent Ins(1,4,5)P(3) signals induced by a nitrogen source in nitrogen-starved yeast cells
    J C Bergsma
    Laboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kasteelpark Arenberg 31, B-3001 Leuven-Heverlee, Flanders, Belgium
    Biochem J 359:517-23. 2001
    ....
  10. ncbi request reprint Molecular cloning of NIPP-1, a nuclear inhibitor of protein phosphatase-1, reveals homology with polypeptides involved in RNA processing
    A Van Eynde
    Afdeling Biochemie, Faculteit Geneeskunde, Katholieke Universiteit Leuven, Belgium
    J Biol Chem 270:28068-74. 1995
    ..Northern analysis revealed a single transcript of 2.2 kilobases in bovine thymus and of 2.4 kilobases in various human tissues...