B Topal

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. ncbi Determinants of complications and adequacy of surgical resection in laparoscopic versus open total gastrectomy for adenocarcinoma
    B Topal
    Department of Abdominal Surgery, University Hospital Leuven, Herestraat 49, 3000, Leuven, Belgium
    Surg Endosc 22:980-4. 2008
  2. pmc Human pancreatic cancer contains a side population expressing cancer stem cell-associated and prognostic genes
    Anke Van den Broeck
    Department of Abdominal Surgery, University Hospitals Leuven, Leuven, Belgium Laboratory of Tissue Plasticity, Research Unit of Embryo and Stem Cells, Department of Development and Regeneration, University of Leuven KU Leuven, Leuven, Belgium
    PLoS ONE 8:e73968. 2013
  3. doi Pancreaticojejunostomy versus pancreaticogastrostomy reconstruction after pancreaticoduodenectomy for pancreatic or periampullary tumours: a multicentre randomised trial
    Baki Topal
    University Hospitals KU Leuven, Abdominal Surgery, Leuven, Belgium
    Lancet Oncol 14:655-62. 2013
  4. pmc Pancreatic cancer circulating tumour cells express a cell motility gene signature that predicts survival after surgery
    Gregory Sergeant
    Department of Abdominal Surgery, University Hospitals Leuven, Herestraat 49, Leuven 3000, Belgium
    BMC Cancer 12:527. 2012
  5. pmc Molecular markers associated with outcome and metastasis in human pancreatic cancer
    Anke Van den Broeck
    Department of Abdominal Surgery, University Hospitals Leuven, Leuven, Belgium
    J Exp Clin Cancer Res 31:68. 2012
  6. ncbi Laparoscopic intrahepatic Glissonian approach for right hepatectomy is safe, simple, and reproducible
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Herestraat 49, Leuven, Belgium
    Surg Endosc 21:2111. 2007
  7. ncbi Effect of centralization of pancreaticoduodenectomy on nationwide hospital mortality and length of stay
    B Topal
    Department of Abdominal Surgery, University Hospital Leuven, Leuven, Belgium
    Br J Surg 94:1377-81. 2007
  8. ncbi Laparoscopic common bile duct stone clearance with flexible choledochoscopy
    B Topal
    Department of Abdominal Surgery, University Hospital Leuven, Herestraat 49, 3000, Leuven, Belgium
    Surg Endosc 21:2317-21. 2007
  9. ncbi Hospital cost-categories of pancreaticoduodenectomy
    B Topal
    Department of Abdominal Surgery, University Hospital Leuven, Leuven, Belgium
    Acta Chir Belg 107:373-7. 2007
  10. doi Clinical models are inaccurate in predicting bile duct stones in situ for patients with gallbladder
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Herestraat 49, Leuven, 3000, Belgium
    Surg Endosc 23:38-44. 2009

Collaborators

Detail Information

Publications32

  1. ncbi Determinants of complications and adequacy of surgical resection in laparoscopic versus open total gastrectomy for adenocarcinoma
    B Topal
    Department of Abdominal Surgery, University Hospital Leuven, Herestraat 49, 3000, Leuven, Belgium
    Surg Endosc 22:980-4. 2008
    ..The role of laparoscopic total gastrectomy (LTG) in the treatment of gastric cancer is controversial. The present study analyzed the morbidity and adequacy of resection in LTG versus open total gastrectomy (OTG) for gastric adenocarcinoma...
  2. pmc Human pancreatic cancer contains a side population expressing cancer stem cell-associated and prognostic genes
    Anke Van den Broeck
    Department of Abdominal Surgery, University Hospitals Leuven, Leuven, Belgium Laboratory of Tissue Plasticity, Research Unit of Embryo and Stem Cells, Department of Development and Regeneration, University of Leuven KU Leuven, Leuven, Belgium
    PLoS ONE 8:e73968. 2013
    ..This tumor subpopulation may represent a valuable therapeutic target given its chemoresistance- and CSC-associated gene expression characteristics with potential prognostic value. ..
  3. doi Pancreaticojejunostomy versus pancreaticogastrostomy reconstruction after pancreaticoduodenectomy for pancreatic or periampullary tumours: a multicentre randomised trial
    Baki Topal
    University Hospitals KU Leuven, Abdominal Surgery, Leuven, Belgium
    Lancet Oncol 14:655-62. 2013
    ..We did a multicentre, randomised superiority trial to compare the outcomes of different reconstructive techniques in patients undergoing pancreaticoduodenectomy for pancreatic or periampullary tumours...
  4. pmc Pancreatic cancer circulating tumour cells express a cell motility gene signature that predicts survival after surgery
    Gregory Sergeant
    Department of Abdominal Surgery, University Hospitals Leuven, Herestraat 49, Leuven 3000, Belgium
    BMC Cancer 12:527. 2012
    ..The aim of the present study was to develop a CTC gene signature and to assess its prognostic relevance after surgery for pancreatic ductal adenocarcinoma (PDAC)...
  5. pmc Molecular markers associated with outcome and metastasis in human pancreatic cancer
    Anke Van den Broeck
    Department of Abdominal Surgery, University Hospitals Leuven, Leuven, Belgium
    J Exp Clin Cancer Res 31:68. 2012
    ..Although the molecular biology of PDAC begins to be revealed, genes or pathways that specifically drive tumour progression or metastasis are not well understood...
  6. ncbi Laparoscopic intrahepatic Glissonian approach for right hepatectomy is safe, simple, and reproducible
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Herestraat 49, Leuven, Belgium
    Surg Endosc 21:2111. 2007
    ..This technique was performed laparoscopically for the last 2 among 10 LRHs, and the results are presented...
  7. ncbi Effect of centralization of pancreaticoduodenectomy on nationwide hospital mortality and length of stay
    B Topal
    Department of Abdominal Surgery, University Hospital Leuven, Leuven, Belgium
    Br J Surg 94:1377-81. 2007
    ..This cohort study analysed the effect of centralization of PD on nationwide hospital mortality and length of hospital stay in Belgium...
  8. ncbi Laparoscopic common bile duct stone clearance with flexible choledochoscopy
    B Topal
    Department of Abdominal Surgery, University Hospital Leuven, Herestraat 49, 3000, Leuven, Belgium
    Surg Endosc 21:2317-21. 2007
    ..No clear guidelines are available on LCBDE with respect to indications for trans-cystic approach versus choledochotomy, or regarding when to use either flexible choledochoscopy (FCD) or intraoperative cholangiography (IOC) guidance...
  9. ncbi Hospital cost-categories of pancreaticoduodenectomy
    B Topal
    Department of Abdominal Surgery, University Hospital Leuven, Leuven, Belgium
    Acta Chir Belg 107:373-7. 2007
    ..In the era of cost-conscious healthcare, hospitals are focusing on costs. Analysis of hospital costs per cost-category may provide indications for potential cost saving measures in pancreaticoduodenectomy (PD)...
  10. doi Clinical models are inaccurate in predicting bile duct stones in situ for patients with gallbladder
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Herestraat 49, Leuven, 3000, Belgium
    Surg Endosc 23:38-44. 2009
    ..This prospective cohort study evaluated the accuracy of clinical models in predicting CBDS for patients who will undergo cholecystectomy for lithiasis...
  11. doi Laparoscopic versus open liver resection of hepatic neoplasms: comparative analysis of short-term results
    B Topal
    Department of Abdominal Surgery, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium
    Surg Endosc 22:2208-13. 2008
    ..Concerns have been raised regarding outcome after laparoscopic resection of hepatic neoplasms. This prospective study compared morbidity and adequacy of surgical margins in laparoscopic (LLR) versus open liver resection (OLR)...
  12. doi Hospital cost categories of one-stage versus two-stage management of common bile duct stones
    B Topal
    Department of Abdominal Surgery, University Hospital Leuven, Leuven, Belgium
    Surg Endosc 24:413-6. 2010
    ..Analysis of hospital costs per cost category may provide indications for potential cost-saving measures in the management of common bile duct stones (CBDS) with gallbladder in situ...
  13. ncbi Morbidity and mortality of laparoscopic vs. open radiofrequency ablation for hepatic malignancies
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
    Eur J Surg Oncol 33:603-7. 2007
    ..The aim of this prospective non-randomized cohort study was to compare morbidity and mortality of laparoscopic (LRFA) vs. open (ORFA) radiofrequency ablation of liver cancer...
  14. ncbi Outpatient laparoscopic cholecystectomy: clinical pathway implementation is efficient and cost effective and increases hospital bed capacity
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Herestraat 49, Leuven, Belgium
    Surg Endosc 21:1142-6. 2007
    ..In the current study, the effect of implementing a clinical pathway has been assessed in terms of outcome for patients scheduled to undergo laparoscopic cholecystectomy, hospital costs, and available bed capacity...
  15. ncbi Determinants of complications in pancreaticoduodenectomy
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
    Eur J Surg Oncol 33:488-92. 2007
    ..This retrospective study examined, using reproducible classification systems, the type and severity of complications as well as the factors to predict them...
  16. ncbi Laparoscopic liver resection using radiofrequency coagulation
    D Hompes
    Abdominal Surgery, University Hospital Gasthuisberg, Herestraat 49, Leuven, 3000, Belgium
    Surg Endosc 21:175-80. 2007
    ..The aim of this prospective, nonrandomized study was to investigate the potential contribution of RF energy to the limitation of intraoperative blood loss in patients undergoing LLR...
  17. ncbi Cancer cell dissemination during curative surgery for colorectal liver metastases
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
    Eur J Surg Oncol 31:506-11. 2005
    ..Haematogenous and intrahepatic cancer cell dissemination was evaluated, and its impact on cancer recurrence was assessed...
  18. ncbi Yield of routine imaging after curative colorectal cancer treatment
    I Jochmans
    Department of Abdominal Surgery, University Clinic Gasthuisberg, Leuven, Belgium
    Acta Chir Belg 108:88-92. 2008
    ..The American Society of Colon and Rectal Surgeons did not recommend routine imaging. This retrospective study assesses the yield of routine imaging to detect recurrent disease...
  19. ncbi Long-term outcome after surgical treatment of nonparasitic splenic cysts
    J Mertens
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Herestraat 49, 3000, Leuven, Belgium
    Surg Endosc 21:206-8. 2007
    ..The optimal treatment for patients with nonparasitic splenic cysts is controversial. This study aimed to evaluate the clinical outcome of patients treated for a symptomatic splenic cyst, and to define a surgical strategy...
  20. ncbi The value of magnetic resonance cholangiopancreatography in predicting common bile duct stones in patients with gallstone disease
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Catholic University Leuven, Herestraat 49, 3000 Leuven, Belgium
    Br J Surg 90:42-7. 2003
    ..The aim of this study was to create a predictive model for CBD stones and to assess the value of magnetic resonance cholangiopancreatography (MRCP) in prediction...
  21. ncbi Gastro-intestinal stromal tumour of the duodenum: extreme presentation in two cases
    D Hompes
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Leuven, Belgium
    Acta Chir Belg 104:110-3. 2004
    ..This work will illustrate that duodenal GIST can occur in extreme presentations, diverging from vague complaints to directly life threatening symptoms...
  22. ncbi Patterns of failure following curative resection of colorectal liver metastases
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Catholic University Leuven, Belgium
    Eur J Surg Oncol 29:248-53. 2003
    ..Several studies have focused on factors determining recurrence and survival rate after curative resection of colorectal liver metastases (LM). Data are lacking with regard to patterns of failure indicating where and when recurrences arise...
  23. doi Results of single-probe microwave ablation of metastatic liver cancer
    R Hompes
    Department of Abdominal Surgery, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium
    Eur J Surg Oncol 36:725-30. 2010
    ..The aim of this study was to evaluate the variability and reproducibility of single-probe MWA vs. radiofrequency ablation (RFA) of liver metastases smaller than 3cm in patients without underlying liver disease...
  24. doi Patterns of recurrence after curative resection of pancreatic ductal adenocarcinoma
    A van den Broeck
    Department of Abdominal Surgery, University Hospital Leuven, Leuven, Belgium
    Eur J Surg Oncol 35:600-4. 2009
    ..Understanding of the patterns of failure after surgery can lead to new insights for novel therapeutic modalities. The aim of the present study is to describe the patterns of recurrence after curative resection of PDAC...
  25. ncbi Clinical value of whole-body emission tomography in potentially curable colorectal liver metastases
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Leuven, Belgium
    Eur J Surg Oncol 27:175-9. 2001
    ..The aim of this prospective study was to evaluate whether patient selection could be improved with pre-operative whole-body 18-fluoro-2-deoxyglucose-positron emission tomography (FDG-PET) scan...
  26. ncbi Transcatheter management of hepatic artery pseudoaneurysm following pancreaticoduodenectomy: a report of three cases
    G Maleux
    Department of Radiology, University Hospitals, Leuven, Belgium
    Acta Chir Belg 104:564-7. 2004
    ..We present our experience in Three patients undergoing transcatheter embolization of hepatic artery pseudoaneurysms detected several weeks after Whipple's operation...
  27. ncbi Aggregated colon cancer cells have a higher metastatic efficiency in the liver compared with nonaggregated cells: an experimental study
    B Topal
    Department of Abdominal Surgery, University Hospital Gasthuisberg, Catholic University Leuven, Leuven, Belgium
    J Surg Res 112:31-7. 2003
    ..The aim of the present study was to compare in the liver the metastatic efficiency of viable nonaggregated colon cancer cells versus cell aggregates for equivalent numbers of cancer cells...
  28. doi The prognostic relevance of tumor hypoxia markers in resected carcinoma of the gallbladder
    G Sergeant
    Department of Abdominal Surgery, University Hospital Leuven, Herestraat 49, Leuven, Belgium
    Eur J Surg Oncol 37:80-6. 2011
    ..Intratumoral hypoxia has been suggested to drive more aggressive tumor behavior. Our aim was to define whether markers of tumor hypoxia are predictors of outcome in patients with gallbladder carcinoma...
  29. ncbi The effect of polyethylene glycol and butyrate on anastomotic healing in the rat colon
    P Fa-Si-Oen
    Department of Abdominal Surgery, University Clinic Gasthuisberg, Leuven, Belgium
    Tech Coloproctol 10:308-11. 2006
    ..The use of mechanical bowel preparation is much debated...
  30. ncbi Rectal washout with cytotoxic solution can be extended to the whole colon
    P P Mariani
    Departments of Abdominal Surgery, Pathology and Liver and Pancreatic Diseases, Laboratory of Hepatology, University Clinic Gasthuisberg, Leuven, Belgium
    Br J Surg 89:1540-4. 2002
    ..To prevent implantation of these cells at the time of restorative proctectomy, the feasibility of retrograde whole-colon irrigation just before surgery was explored...
  31. ncbi Laparoscopic liver resection of benign liver tumors
    B Descottes
    Hopital Universitaire Dupuyten, Limoges, France
    Surg Endosc 17:23-30. 2003
    ..The objective of this study was to assess the feasibility, safety, and outcome of laparoscopic liver resection for benign liver tumors in a multicenter setting...
  32. doi Prognostic significance of extracapsular lymph node involvement in patients with adenocarcinoma of the ampulla of Vater (Br J Surg 2008; 95: 735-743)
    G Sergeant
    Br J Surg 95:1188; author reply 1188-9. 2008