Vincent N S Thijs
Affiliation: Katholieke Universiteit Leuven
- Relationship between severity of MR perfusion deficit and DWI lesion evolutionV N Thijs
Stanford Stroke Center, Department of Neurology and Neurological Sciences, Stanford University Medical Center, Palo Alto, CA, USA
Neurology 57:1205-11. 2001....
- Microbleeds and the risk of recurrent strokeVincent Thijs
Department of Neurology, Vesalius Research Center, University Hospitals, Herestraat 49, B3000 Leuven, Belgium
Stroke 41:2005-9. 2010..We studied the risk of recurrent cerebrovascular events in patients who had a transient ischemic attack or ischemic stroke and who had evidence of microbleeds on MRI...
- Randomized, placebo-controlled, dose-ranging clinical trial of intravenous microplasmin in patients with acute ischemic strokeVincent N S Thijs
Department of Neurology, University Hospitals Leuven, Leuven, Belgium
Stroke 40:3789-95. 2009..It has demonstrated efficacy in experimental animal models of stroke and tolerability in healthy volunteers. We tested the tolerability of microplasmin in patients with acute ischemic stroke...
- Network meta-analysis: simultaneous meta-analysis of common antiplatelet regimens after transient ischaemic attack or strokeVincent Thijs
Department of Neurology, University Hospitals Leuven, VIB Herestraat 49, 3000 Leuven, Belgium
Eur Heart J 29:1086-92. 2008..Network meta-analysis could be used to synthesize accumulating evidence from clinical trials in a broad range of vascular disorders...
- Cost of hospitalization for cerebrovascular disorders in BelgiumVincent Thijs
Department of Neurology, University Hospitals Leuven, Belgium
Acta Neurol Belg 111:104-10. 2011..There is only scarce information on the incidence and costs of stroke in Belgium. Knowledge of these figures permits targeted allocation of resources and aids cost efficacy estimates...
- Clinical and radiological correlates of reduced cerebral blood flow measured using magnetic resonance imagingVincent N Thijs
Department of Neurology, UZ Gasthuisberg, Katholieke Universiteit Leuven, Herestraat 49, 3000 Leuven, Belgium
Arch Neurol 59:233-8. 2002..Reduced apparent diffusion coefficient (ADC) values of brain tissue are associated with reductions in regional CBF in animal stroke models...
- Influence of arterial input function on hypoperfusion volumes measured with perfusion-weighted imagingVincent N Thijs
Department of Neurology, UZ Gasthuisberg, Herestraat 49, B 3000 Leuven, Belgium
Stroke 35:94-8. 2004..We studied the effect of varying the location of measurement of AIF on the volume of hypoperfusion. We compared the volumes of hypoperfusion obtained with different AIFs with the final ischemic lesion volume...
- Coexistence of CADASIL and Alzheimer's diseaseV Thijs
Department of Neurology, UZ Gasthuisberg, Katholieke Universiteit Leuven, Belgium
J Neurol Neurosurg Psychiatry 74:790-2. 2003..Mutations in the APP, PSEN1, and PSEN2 genes were not identified. Neuropathological findings of Alzheimer's disease may be found in CADASIL patients...
- Intermediate short-term outcomes after brain computed tomography and magnetic resonance imaging in neurology outpatientsP Demaerel
Department of Radiology University Hospital, Leuven, Belgium
Med Decis Making 21:444-50. 2001....
- Outcome of carotid artery stenting at 2 years follow-up: comparison of nitinol open cell versus stainless steel closed cell stent designG Maleux
Department of Radiology, University Hospitals Leuven, Leuven, Belgium
J Cardiovasc Surg (Torino) 50:669-75. 2009..The aim of this study was to compare the clinical and ultrasound outcome of carotid artery stenting at 2-year follow-up in patients treated with open-cell nitinol stents versus patients treated with closed cell stainless steel stents...
- The Belgian experience with intravenous thrombolysis for acute ischemic strokeP Vanacker
Department of Neurology, AZ Sint Jan Brugge Oostende, Brugge, Belgium
Acta Neurol Belg 110:157-62. 2010..This prospective observational register evaluates the safety and efficacy of intravenous thrombolysis with rtPA (recombinant tissue Plasminogen Activator) for ischemic stroke in routine clinical practice...
- Association of early CT abnormalities, infarct size, and apparent diffusion coefficient reduction in acute ischemic strokeDiederik M Somford
Stanford Stroke Center, Palo Alto, CA 94304, USA
AJNR Am J Neuroradiol 25:933-8. 2004..We examined the relationship between early CT findings, ischemic lesion volume on DW images, and edema subtype...
- The MRA-DWI mismatch identifies patients with stroke who are likely to benefit from reperfusionMaarten G Lansberg
Stanford Stroke Center, 701 Welch Road, Suite B325, Palo Alto, CA 94304 9705, USA
Stroke 39:2491-6. 2008....
- Optimal outcome measures for detecting clinical benefits of early reperfusion: insights from the DEFUSE StudyWataru Kakuda
Department of Rehabilitation Medicine, Jikei University School of Medicine, Tokyo, Japan
J Stroke Cerebrovasc Dis 17:235-40. 2008..There is no consensus regarding which clinical outcome scales are the most sensitive indicators of early reperfusion in patients with acute stroke...
- Relationships between infarct growth, clinical outcome, and early recanalization in diffusion and perfusion imaging for understanding stroke evolution (DEFUSE)Jean Marc Olivot
Department of Neurology and Neurological Sciences and the Stanford Stroke Center, Stanford University Medical Center, 701 Welch Road, Suite 325, Palo Alto, CA 94304, USA
Stroke 39:2257-63. 2008..The purpose of this study was to determine the relationships between ischemic lesion growth, recanalization, and clinical response in stroke patients with and without a perfusion/diffusion mismatch...
- Risk factors of symptomatic intracerebral hemorrhage after tPA therapy for acute strokeMaarten G Lansberg
Stanford University, Stanford Stroke Center, Palo Alto, California 94304, USA
Stroke 38:2275-8. 2007..MRI-based variables have generally not been included in predictive models, and little is known about the influence of reperfusion on SICH risk...
- Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) studyGregory W Albers
Department of Neurology and Neurological Sciences and the Stanford Stroke Center, Stanford University Medical Center, Stanford, CA 94304, USA
Ann Neurol 60:508-17. 2006..To determine whether prespecified baseline magnetic resonance imaging (MRI) profiles can identify stroke patients who have a robust clinical response after early reperfusion when treated 3 to 6 hours after symptom onset...
- Diffusion-weighted MR imaging in acute ischemia: value of apparent diffusion coefficient and signal intensity thresholds in predicting tissue at risk and final infarct sizeDong Gyu Na
Department of Radiology, Stanford University Medical Center, Stanford, CA 94305 5105, USA
AJNR Am J Neuroradiol 25:1331-6. 2004..This study was performed to determine whether pixel-based apparent diffusion coefficient (ADC) and signal intensity ratio are helpful diffusion-weighted (DW) imaging metrics to predict tissue at risk for infarction...
- Optimal definition for PWI/DWI mismatch in acute ischemic stroke patientsWataru Kakuda
Department of Rehabilitation Medicine, Jikei University School of Medicine, Minato ku, Tokyo, Japan
J Cereb Blood Flow Metab 28:887-91. 2008..Defining mismatch with a larger PWI/DWI ratio may provide greater power for detecting beneficial effects of reperfusion...
- Evaluation of the clinical-diffusion and perfusion-diffusion mismatch models in DEFUSEMaarten G Lansberg
Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA 94304, USA
Stroke 38:1826-30. 2007..The clinical-diffusion mismatch (CDM) model is an alternative method that is technically less challenging because it does not require perfusion-weighted imaging. This study is an evaluation of these 2 models in the DEFUSE dataset...