S Simoens

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. ncbi Pharmaco-economics of community maintenance for opiate dependence: a review of evidence and methodology
    Steven Simoens
    Pharmacy Practice Research Centre, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, Herestraat 49, P O Box 521, 3000 Leuven, Belgium
    Drug Alcohol Depend 84:28-39. 2006
  2. ncbi International comparison of generic medicine prices
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Belgium
    Curr Med Res Opin 23:2647-54. 2007
  3. doi Which barriers prevent the efficient use of resources in medical device sectors?
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    Appl Health Econ Health Policy 7:209-17. 2009
  4. doi The use of intravenous immunoglobulins in Belgium
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    Int Arch Allergy Immunol 154:173-6. 2011
  5. ncbi Health technologies for rare diseases: does conventional HTA still apply?
    Steven Simoens
    KU Leuven, Department of Pharmaceutical and Pharmacological Sciences, Herestraat 49, O and N 2, P O Box 521, 3000 Leuven, Belgium 32 1632 3465 32 1632 3468
    Expert Rev Pharmacoecon Outcomes Res 14:315-7. 2014
  6. pmc Factors affecting the cost effectiveness of antibiotics
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, P O Box 521, Herestraat 49, 3000 Leuven, Belgium
    Chemother Res Pract 2011:249867. 2011
  7. pmc Assessment of methodological quality of economic evaluations in belgian drug reimbursement applications
    Steven Simoens
    KU Leuven Department of Pharmaceutical and Pharmacological Sciences, Leuven, Belgium
    PLoS ONE 8:e85411. 2013
  8. pmc Biosimilar medicines and cost-effectiveness
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    Clinicoecon Outcomes Res 3:29-36. 2011
  9. pmc How to assess the value of medicines?
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven Leuven, Belgium
    Front Pharmacol 1:115. 2010
  10. doi Patient co-payment and adherence to statins: a review and case studies
    Steven Simoens
    Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Onderwijs en Navorsing 2, Herestraat 49, P O Box 521, 3000, Leuven, Belgium
    Cardiovasc Drugs Ther 28:99-109. 2014

Collaborators

Detail Information

Publications83

  1. ncbi Pharmaco-economics of community maintenance for opiate dependence: a review of evidence and methodology
    Steven Simoens
    Pharmacy Practice Research Centre, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, Herestraat 49, P O Box 521, 3000 Leuven, Belgium
    Drug Alcohol Depend 84:28-39. 2006
    ..There is a need for better-designed economic evaluations that examine whether treatment benefits exceed costs, in terms of both financial benefits and health gain...
  2. ncbi International comparison of generic medicine prices
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Belgium
    Curr Med Res Opin 23:2647-54. 2007
    ....
  3. doi Which barriers prevent the efficient use of resources in medical device sectors?
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    Appl Health Econ Health Policy 7:209-17. 2009
    ..Additionally, there is a need for more formal assessment systems for medical devices...
  4. doi The use of intravenous immunoglobulins in Belgium
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    Int Arch Allergy Immunol 154:173-6. 2011
    ..This study aims to document the use of intravenous immunoglobulins in registered and off-label conditions in Belgian hospitals...
  5. ncbi Health technologies for rare diseases: does conventional HTA still apply?
    Steven Simoens
    KU Leuven, Department of Pharmaceutical and Pharmacological Sciences, Herestraat 49, O and N 2, P O Box 521, 3000 Leuven, Belgium 32 1632 3465 32 1632 3468
    Expert Rev Pharmacoecon Outcomes Res 14:315-7. 2014
    ..Past experiences demonstrate that the specific characteristics of health technologies for rare diseases can fit in the conventional health technology assessment paradigm by means of multi-criteria decision analysis. ..
  6. pmc Factors affecting the cost effectiveness of antibiotics
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, P O Box 521, Herestraat 49, 3000 Leuven, Belgium
    Chemother Res Pract 2011:249867. 2011
    ..Physicians need to take into account these factors when prescribing an antibiotic and assess whether a specific antibiotic treatment adds sufficient value to justify its costs...
  7. pmc Assessment of methodological quality of economic evaluations in belgian drug reimbursement applications
    Steven Simoens
    KU Leuven Department of Pharmaceutical and Pharmacological Sciences, Leuven, Belgium
    PLoS ONE 8:e85411. 2013
    ..This paper aims to assess the methodological quality of economic evaluations included in Belgian reimbursement applications for Class 1 drugs...
  8. pmc Biosimilar medicines and cost-effectiveness
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    Clinicoecon Outcomes Res 3:29-36. 2011
    ....
  9. pmc How to assess the value of medicines?
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven Leuven, Belgium
    Front Pharmacol 1:115. 2010
    ..Alternatively, the generalized optimization framework and multi-criteria decision analysis make it possible to consider other criteria in addition to value...
  10. doi Patient co-payment and adherence to statins: a review and case studies
    Steven Simoens
    Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Onderwijs en Navorsing 2, Herestraat 49, P O Box 521, 3000, Leuven, Belgium
    Cardiovasc Drugs Ther 28:99-109. 2014
    ....
  11. doi Trends in generic prescribing and dispensing in Europe
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, PO Box 521, Herestraat 49, 3000 Leuven, Belgium
    Expert Rev Clin Pharmacol 1:497-503. 2008
    ..Finally, the development of biosimilars will probably become an important area of growth for the pharmaceutical industry over the next 5 years. ..
  12. pmc Paying for the Orphan Drug System: break or bend? Is it time for a new evaluation system for payers in Europe to take account of new rare disease treatments?
    Wills Hughes-Wilson
    EU Committee of Experts on Rare Diseases EUCERD, Global Public Policy and Government Relations, SOBI Swedish Orphan Biovitrum, Tomtebodvägen, 23A, Solna, Sweden
    Orphanet J Rare Dis 7:74. 2012
    ..The authors believe that this could, therefore, facilitate the approach for all stakeholders...
  13. pmc Personalizing health care: feasibility and future implications
    Brian Godman
    Department of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska Institutet, Karolinska University Hospital Huddinge, SE 141 86, Stockholm, Sweden
    BMC Med 11:179. 2013
    ..Overall, personalized medicine has the potential to revolutionize care. However, current challenges and concerns need to be addressed to enhance its uptake and funding to benefit patients. ..
  14. doi Market entry of biosimilar low-molecular-weight heparins in Europe: opportunities and challenges
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmacoeconomics, KU Leuven, 3000 Leuven, Belgium
    Semin Thromb Hemost 39:250-7. 2013
    ....
  15. doi Terminal patients in Belgian nursing homes: a cost analysis
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    Eur J Health Econ 14:407-13. 2013
    ....
  16. doi Preventing COPD exacerbations with macrolides: a review and budget impact analysis
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmacoeconomics, KU Leuven, Onderwijs en Navorsing 2, P O Box 521, Herestraat 49, 3000 Leuven, Belgium
    Respir Med 107:637-48. 2013
    ....
  17. doi Generic atorvastatin, the Belgian statin market and the cost-effectiveness of statin therapy
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, KU Leuven, Onderwijs en Navorsing 2 bus 521, Herestraat 49, 3000 Leuven, Belgium
    Cardiovasc Drugs Ther 27:49-60. 2013
    ..This study examines how the market entry of generic atorvastatin influences the Belgian statin market and the cost-effectiveness of statin therapy...
  18. doi What is the value for money of medicines? A registry study
    S Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    J Clin Pharm Ther 37:182-6. 2012
    ..Economic evaluation is used to assess the value for money of medicines and inform pharmaceutical pricing/reimbursement decisions in many countries. This paper aims to report on estimates of the value for money of medicines in Europe...
  19. doi Biosimilars and market access: a question of comparability and costs?
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, Herestraat 49, P O Box 521, 3000 Leuven, Belgium
    Target Oncol 7:227-31. 2012
    ..To date, many key concepts (like clinically meaningful differences) remain undefined and the question of the degree of comparability is not yet resolved...
  20. doi Pharmaco-economic aspects of sipuleucel-T
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    Hum Vaccin Immunother 8:506-8. 2012
    ..However, the current absence of markers to identify eligible patients and to assess treatment response inhibits the implementation of a risk-sharing arrangement for sipuleucel-T...
  21. doi The cost-effectiveness of immunotherapy for respiratory allergy: a review
    S Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Leuven, Belgium
    Allergy 67:1087-105. 2012
    ..There is a need for economic evaluations based on high-quality prospective and long-term clinical studies comparing immunotherapy with pharmacotherapy in real-life practice and comparing sublingual with subcutaneous immunotherapy...
  22. doi Orphan drugs for rare diseases: is it time to revisit their special market access status?
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, KU Leuven, Leuven, Belgium
    Drugs 72:1437-43. 2012
    ..Governments should consider carefully the right incentive strategy for R&D of orphan drugs in rare diseases...
  23. pmc Following up patients with depression after hospital discharge: a mixed methods approach
    Franciska A Desplenter
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, ON2 Herestraat 49 P, O, Box 521, 3000 Leuven, Belgium
    Int J Ment Health Syst 5:28. 2011
    ..abstract:..
  24. pmc Palliative inpatients in general hospitals: a one day observational study in Belgium
    Marianne S Desmedt
    Unité de Soins Continus, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, 10 Avenue Hippocrate, 1200 Bruxelles, Belgique
    BMC Palliat Care 10:2. 2011
    ..abstract:..
  25. ncbi Cardiovascular drug use prior to diagnosis of diabetes: a pilot study in community pharmacy
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    Int J Pharm Pract 17:127-9. 2009
    ..This pilot study aimed to investigate cardiovascular drug use in patients with a subsequent diagnosis of diabetes using data extracted from 200 community pharmacies in the Belgian township of Hasselt...
  26. doi Endometriosis cost assessment (the EndoCost study): a cost-of-illness study protocol
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    Gynecol Obstet Invest 71:170-6. 2011
    ..The EndoCost study aims to calculate the costs of endometriosis from a societal perspective...
  27. doi Pharmacoeconomics of anti-epileptic drugs as adjunctive therapy for refractory epilepsy
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, O and N 2 P O Box 521, Herestraat 49, 3000 Leuven, Belgium
    Expert Rev Pharmacoecon Outcomes Res 10:309-15. 2010
    ..However, there is a need for more, better-designed and comprehensive economic evaluations of adjunctive therapy for refractory epilepsy with anti-epileptic drugs...
  28. doi The costs of treating terminal patients
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    J Pain Symptom Manage 40:436-48. 2010
    ..In addition to the effectiveness of terminal care, policy makers and health care payers are concerned about the costs of treating terminal patients in a context of spiraling health care costs and limited resources...
  29. pmc Health economic assessment: cost-effectiveness thresholds and other decision criteria
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium
    Int J Environ Res Public Health 7:1835-40. 2010
    ....
  30. doi Use of economic evaluation in decision making: evidence and recommendations for improvement
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    Drugs 70:1917-26. 2010
    ..These issues require further attention from researchers, policy makers, healthcare payers, healthcare professionals and pharmaceutical companies with a view to optimizing the use of economic evaluation in decision making...
  31. doi Treatment of primary immunodeficiency with Kiovig: a literature review
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    Adv Ther 27:142-9. 2010
    ..The aim of this study is to carry out a literature review of a ready-to-use 10% liquid immunoglobulin preparation, Kiovig (Baxter, Brussels, Belgium), in the treatment of primary immunodeficiency...
  32. doi Costs of terminal patients who receive palliative care or usual care in different hospital wards
    Steven Simoens
    Katholieke Universiteit Leuven, Leuven, Belgium
    J Palliat Med 13:1365-9. 2010
    ..This study aims to measure the hospital costs of treating terminal patients in Belgium from the health care payer perspective. Also, this study compares the costs of palliative and usual care in different types of hospital wards...
  33. pmc Consumption patterns and in vitro resistance of Streptococcus pneumoniae to fluoroquinolones
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, Herestraat 49, P O Box 521, 3000 Leuven, Belgium
    Antimicrob Agents Chemother 55:3051-3. 2011
    ..The MIC distributions of moxifloxacin and levofloxacin in S. pneumoniae isolates remained stable during 2004 to 2009, and the level of resistance to moxifloxacin and levofloxacin was low (≤1%)...
  34. doi Budget impact analysis of adjunctive therapy with lacosamide for partial-onset epileptic seizures in Belgium
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium
    J Med Econ 14:299-304. 2011
    ....
  35. doi How much is the life of a cancer patient worth? A pharmaco-economic perspective
    S Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven Hospital Pharmacy, University Hospitals Leuven, Leuven, Belgium
    J Clin Pharm Ther 36:249-56. 2011
    ....
  36. doi Lacosamide as adjunctive therapy for partial-onset epileptic seizures: a review of the clinical and economic literature
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmacoeconomics, Katholieke Universiteit Leuven, Leuven, Belgium
    Curr Med Res Opin 27:1329-38. 2011
    ..This article provides a short but comprehensive pharmacotherapeutic update of adjunctive therapy with lacosamide for partial-onset seizures in adult patients...
  37. ncbi Use and costs of anti-secretory and cardiovascular co-medication in osteoarthritis patients treated with selective or non-selective NSAIDS
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, Herestraat 49, P O Box 521, 3000, Leuven, Belgium
    Pharm World Sci 28:309-17. 2006
    ..This study aims to compare use and costs of anti-secretory and cardiovascular co-medication in osteoarthritis patients treated with selective or non-selective NSAIDs...
  38. pmc Pricing and reimbursement of orphan drugs: the need for more transparency
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, O and N2 bus 521, Herestraat 49, 3000 Leuven, Belgium
    Orphanet J Rare Dis 6:42. 2011
    ..Such an approach should be targeted at demonstrating the relative effectiveness, cost-effectiveness and economic viability of orphan drugs with a view to informing pricing and reimbursement decisions...
  39. doi Non-health-care costs associated with endometriosis
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    Hum Reprod 26:2363-7. 2011
    ..This study aims to quantify the non-health-care costs of endometriosis in a sample of Belgian patients over a 30-month period...
  40. doi Review of the cost-effectiveness of interventions to improve seamless care focusing on medication
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke, Universiteit Leuven, Onderwijs en Navorsing 2, Herestraat 49, P O Box 521, 3000, Leuven, Belgium
    Int J Clin Pharm 33:909-17. 2011
    ..This review of the international literature aims to assess the evidence and its methodological quality relating to the cost-effectiveness of interventions to improve seamless care focusing on medication...
  41. pmc Health economic assessment: a methodological primer
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    Int J Environ Res Public Health 6:2950-66. 2009
    ..Key references are provided for those readers who wish a more advanced understanding of health economic assessments...
  42. doi International comparison of orthotic brace prices
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, Herestraat 49, P O Box 521, 3000, Leuven, Belgium
    Eur J Health Econ 10:149-55. 2009
    ..Belgian prices tended to exceed prices in other countries for the selected neck, wrist and knee braces. There seems to be scope for reducing Belgian prices of selected braces...
  43. doi Reforming the Belgian market for orthotic braces: what can we learn from the international experience?
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, P O Box 521, Herestraat 49, 3000 Leuven, Belgium
    Health Policy 86:195-203. 2008
    ..This article aims to review regulation governing outpatient orthotic braces (neck, wrist and knee braces) in France, the Netherlands and Sweden with a view to reforming the Belgian market...
  44. ncbi Clinical and economic analysis of antimicrobial therapy of chronic obstructive pulmonary disease exacerbations
    S Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    Int J Clin Pract 61:200-6. 2007
    ..Fluoroquinolones were used to treat more severe exacerbations. Treatment of acute exacerbations of COPD imposes a significant clinical and economic burden on patients, the healthcare system and the society...
  45. ncbi Endometriosis: cost estimates and methodological perspective
    S Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, PO Box 521, Herestraat 49, 3000 Leuven, Belgium
    Hum Reprod Update 13:395-404. 2007
    ..There is a need for more and better-designed studies that carry out longitudinal analyses of patients until the cessation of their symptoms or that model the chronic nature of endometriosis...
  46. ncbi Pharmacoeconomics of the management of acute exacerbations of chronic obstructive pulmonary disease
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, K U Leuven, Onderwijs en Navorsing 2, Leuven, Belgium
    Expert Opin Pharmacother 8:633-48. 2007
    ..It presents estimates of the level and distribution of costs associated with exacerbations and reports on the cost-effectiveness or cost-utility of antimicrobial therapy and other approaches to the management of exacerbations...
  47. ncbi Economic evaluation and decision making: reimbursing trastuzumab in early-stage breast cancer
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmacoeconomics, Katholieke Universiteit Leuven, Leuven, Belgium
    Pharmacoeconomics 25:181-5. 2007
  48. ncbi Economic aspects of antimicrobial therapy of acute exacerbations of COPD
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, KU Leuven, Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium
    Respir Med 101:15-26. 2007
    ..The small number of economic evaluations and their methodological limitations precludes the recommendation of a specific antibiotic for use in the management of COPD exacerbations on economic grounds...
  49. ncbi Drawing on international experience to reform the Belgian market for ostomy appliances
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, K U Leuven, Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium
    Health Policy 80:273-80. 2007
    ....
  50. ncbi A pharmacoeconomic review of the management of respiratory tract infections with moxifloxacin
    Steven Simoens
    Katholieke Universiteit Leuven, Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Onderwijs en Navorsing 2, Herestraat 49, PO Box 521, 3000 Leuven, Belgium
    Expert Opin Pharmacother 9:1735-44. 2008
    ..Moxifloxacin, a fluoroquinolone, has demonstrated its safety and effectiveness in the management of community-acquired pneumonia, acute exacerbations of chronic bronchitis and acute bacterial sinusitis...
  51. doi Patient experiences of over-the-counter medicine purchases in Flemish community pharmacies
    Steven Simoens
    Faculty of Pharmaceutical Sciences, Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, 3000, Belgium
    Pharm World Sci 31:450-7. 2009
    ..However, little is known of patient experiences of pharmacy distribution and services related to OTC medicines. The aim of this study is to explore patient experiences of purchasing OTC medicines in Flemish community pharmacies...
  52. doi Search and destroy policy for methicillin-resistant Staphylococcus aureus: cost-benefit analysis
    Steven Simoens
    Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Belgium
    J Adv Nurs 65:1853-9. 2009
    ....
  53. doi Evidence for moxifloxacin in community-acquired pneumonia: the impact of pharmaco-economic considerations on guidelines
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven Onderwijs en Navorsing 2, Herestraat 49, P O Box 521, 3000 Leuven, Belgium
    Curr Med Res Opin 25:2447-57. 2009
    ..This paper aims to conduct an international literature review with a view to assessing the impact of pharmaco-economic considerations of CAP treatment with moxifloxacin on recent guidelines...
  54. doi Analysis of drug authentication at the point of dispensing in Belgian and Greek community pharmacies
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, O and N 2, Herestraat 49, PO Box 521, 3000 Leuven, Belgium
    Ann Pharmacother 43:1701-6. 2009
    ..Authentication processes based on mass serialization technology may help to make the drug supply more secure for patients...
  55. doi Ostomy appliance prices in Europe
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, PO Box 521, Herestraat 49, 3000 Leuven, Belgium
    J Med Econ 12:17-24. 2009
    ..This article aims to compare market prices (i.e., third-party reimbursement and patient co-payment) of one-piece and two-piece colostomy, ileostomy and ureterostomy appliances in Belgium, Denmark, England and the Netherlands in 2005...
  56. pmc Developing competitive and sustainable Polish generic medicines market
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Onderwijs en Navorsing, 3000 Leuven, Belgium
    Croat Med J 50:440-8. 2009
    ..To descriptively analyze the policy environment surrounding the Polish generic medicines retail market...
  57. doi Health economics of medical devices: opportunities and challenges
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Belgium
    J Med Econ 11:713-7. 2008
    ..In addition, countries need to implement frameworks for the assessment of new and emerging medical devices with a view to taking pricing and reimbursement decisions...
  58. doi Health economics of market access for biopharmaceuticals and biosimilars
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    J Med Econ 12:211-8. 2009
    ..A literature search was carried out of PubMed, Centre for Reviews and Dissemination databases, Cochrane Database of Systematic Reviews and EconLit up to March 2009...
  59. doi Pharmacoeconomics of immunoglobulins in primary immunodeficiency
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, O and N 2 PO Box 521, Herestraat 49, 3000 Leuven, Belgium
    Expert Rev Pharmacoecon Outcomes Res 9:375-86. 2009
    ..Demand for immunoglobulins has increased over time, leading to periodic shortages and emphasizing the importance of its appropriate use...
  60. doi Do tariffs and prices correspond with costs? A case study of orthotic braces
    Steven Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, 3000, Leuven, Belgium
    J Med Econ 11:245-54. 2008
    ..This article aims to calculate production and distribution costs of a prefabricated hard neck and knee brace and to explore whether Belgian tariffs and actual retail prices correspond with estimated costs of these two braces...
  61. doi Market uptake of orphan drugs--a European analysis
    E Picavet
    Research Centre for Pharmaceutical Care and Pharmaco economics, KU Leuven, Leuven, Belgium
    J Clin Pharm Ther 37:664-7. 2012
    ....
  62. ncbi Follow-up of antibiotic prophylaxis: impact on compliance with guidelines and financial outcomes
    L Willems
    University Hospitals Leuven, Leuven, Belgium
    J Hosp Infect 60:333-9. 2005
    ..Moreover, the range of antibiotics consumed during standard prophylaxis narrowed. This follow-up programme thus reduced antibiotic costs, improved profitability and increased physician compliance with guidelines...
  63. doi Do we need authorized orphan drugs when compounded medications are available?
    M Dooms
    Hospital Pharmacy, University Hospitals Leuven, Leuven, Belgium
    J Clin Pharm Ther 38:1-2. 2013
    ..This Commentary aims to present a number of case studies questioning the need for designating compounded medications with a long history of effective use, which is well-supported by published clinical evidence...
  64. ncbi Treating respiratory tract infections in ambulatory care in Belgium: fluoroquinolone consumption and resistance development
    S Simoens
    Centre for Drug and Patient Information, Faculty of Pharmaceutical Sciences, K U Leuven, Edward van Evenstraat 4, 3000 Leuven, Belgium
    Int J Antimicrob Agents 26:62-8. 2005
    ..The use of new fluoroquinolones (levofloxacin, moxifloxacin) and the ongoing use of older fluoroquinolones have not led to increased pneumococcal resistance, which remained below 1% for levofloxacin and was 0% for moxifloxacin...
  65. doi Continuous versus on-demand pharmacotherapy of allergic rhinitis: evidence and practice
    Gert Laekeman
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Onderwijs en Navorsing 2, Herestraat 49, Leuven, Belgium
    Respir Med 104:615-25. 2010
    ..With regard to the cost and cost-effectiveness implications of continuous therapy versus on-demand therapy, more studies are necessary before definitive conclusions may be made...
  66. ncbi The impact of informing psychiatric patients about their medication: a systematic review
    Franciska A M Desplenter
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    Pharm World Sci 28:329-41. 2006
    ..This literature study explores the impact of educational interventions about medicines for psychiatric patients on adherence, knowledge and economic, clinical and humanistic outcomes...
  67. ncbi Implementing a hospital guideline on pneumonia: a semi-quantitative review
    Pieter Jan Cortoos
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Belgium
    Int J Qual Health Care 19:358-67. 2007
    ..To quantify the impact of different guideline implementation interventions to improve treatment of community-acquired pneumonia (CAP) in a hospital setting...
  68. doi Increasing nurse staffing levels in Belgian cardiac surgery centres: a cost-effective patient safety intervention?
    Koen Van den Heede
    Research Associate Center for Health Services and Nursing Research, Katholieke Universiteit Leuven, Belgium
    J Adv Nurs 66:1291-6. 2010
    ..This paper is a report of a cost-effectiveness analysis from a hospital perspective of increased nurse staffing levels (to the level of the 75th percentile) in Belgian general cardiac postoperative nursing units...
  69. doi Opposing expectations and suboptimal use of a local antibiotic hospital guideline: a qualitative study
    Pieter Jan Cortoos
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, O and N 2, Herestraat 49, PB 521, B 3000 Leuven, Belgium
    J Antimicrob Chemother 62:189-95. 2008
    ..The aim of this study was to determine the opinions and problems concerning the use of a local antibiotic hospital guideline in a 1900-bed tertiary-care, university teaching hospital...
  70. doi Discharge management for patients in Flemish psychiatric hospitals
    Franciska Desplenter
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    J Eval Clin Pract 16:1116-23. 2010
    ..This study aimed to describe the profile of patients receiving discharge management in Flemish psychiatric hospitals as well as to analyse the discharge management indicators of these hospitals on micro and meso level...
  71. doi Pharmacotherapy of allergic rhinitis: a pharmaco-economic approach
    S Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit Leuven, Leuven, Belgium
    Allergy 64:85-95. 2009
    ..Finally, the economic value of pharmacotherapy of AR is influenced by the perspective of the economic evaluation, relative effectiveness and costs of available drugs, patient compliance with treatment...
  72. pmc The effectiveness of community maintenance with methadone or buprenorphine for treating opiate dependence
    Steven Simoens
    Drug and Patient Information, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Belgium
    Br J Gen Pract 55:139-46. 2005
    ..Opiate dependence is a major health and social issue in many countries. A mainstay of therapy has been methadone maintenance treatment, but other treatments, particularly buprenorphine, are increasingly being considered...
  73. pmc Incidence and drug treatment of emotional distress after cancer diagnosis: a matched primary care case-control study
    F Desplenter
    Academic Primary Care, University of Aberdeen, Foresterhill, Polwarth Building, Aberdeen AB25 2ZD, UK
    Br J Cancer 107:1644-51. 2012
    ....
  74. pmc International trends in lifelong learning for pharmacists
    Annelies Driesen
    Katholieke Universiteit Leuven, Belgium
    Am J Pharm Educ 71:52. 2007
    ..This approach combines the controllability by regulatory organizations that CE requires with the advantage of sustained behavior change seen in successful CPD programs...
  75. ncbi Pharmaceutical policy regarding generic drugs in Belgium
    Steven Simoens
    Centre for Drug and Patient Information, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    Pharmacoeconomics 23:755-66. 2005
    ....
  76. ncbi Using the Delphi technique in economic evaluation: time to revisit the oracle?
    S Simoens
    Research Centre for Pharmaceutical Care and Pharmaco economics, Katholieke Universiteit, Leuven, Belgium
    J Clin Pharm Ther 31:519-22. 2006
    ..The aim of this study was to describe the methodology of the Delphi technique, to present a case for using the technique in economic evaluation, and to provide recommendations to improve such use...
  77. doi Medication information for Flemish inpatients with major depression: evaluation and construct validity of the Consumer Information Rating Form
    F Desplenter
    Research Centre for Pharmaceutical Care and Pharmaco economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    J Clin Pharm Ther 34:645-55. 2009
    ....
  78. doi Economic effects of clinical pharmacy interventions: a literature review
    Thomas De Rijdt
    Department of Pharmacy, University Hospitals, Leuven, Belgium
    Am J Health Syst Pharm 65:1161-72. 2008
    ..Economic evaluations of clinical pharmacy interventions are reviewed...
  79. ncbi Applying health technology assessment to pharmaceutical care: pitfalls and future directions
    Steven Simoens
    Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Edward van Evenstraat 4, 3000 Leuven, Belgium
    Pharm World Sci 27:73-5. 2005
    ..In order to increase the usefulness of study findings to policy-makers, researchers need to identify the multiple objectives that policy-makers pursue, and show how study findings will aid policy-makers in attaining these objectives...
  80. ncbi Experiences of Organization for Economic Cooperation and Development countries with recruiting and retaining physicians in rural areas
    Steven Simoens
    Faculty of Pharmaceutical Sciences, Catholic University Leuven, Belgium
    Aust J Rural Health 12:104-11. 2004
    ....
  81. ncbi Voluntary or compulsory health care reform? The case of primary care organisations in Scotland
    Steven Simoens
    Faculty of Pharmaceutical Sciences, Drug and Patient Information, Catholic University Leuven, Edward van Evenstraat 4, 3000 Leuven, Belgium
    Health Policy 72:351-8. 2005
    ..This suggests that voluntary participation in these new primary care organisations may reduce rather than exacerbate inequalities in the provision of primary care...
  82. ncbi Estimation and comparison of ostomy appliance costs with tariffs in Belgium
    Veerle Vanleene
    Deloitte Business Advisory, Antwerp, Belgium
    Eur J Health Econ 9:17-22. 2008
    ..06 and the tariffs of euro 6.05. In the absence of publicly disclosed information on the cost structure of appliances, estimating ostomy appliance costs is valuable to reimbursement agencies when setting tariffs...
  83. doi A cost-effectiveness analysis of antimicrobial treatment of community-acquired pneumonia taking into account resistance in Belgium
    Monique Martin
    i3 Innovus, Uxbridge, UK
    Curr Med Res Opin 24:737-51. 2008
    ..This article assesses the cost-effectiveness of outpatient antimicrobial treatment of community-acquired pneumonia (CAP) taking into account resistance in Belgium...