Affiliation: Katholieke Universiteit Leuven
- Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritisEvelien Schurgers
Laboratory of Immunobiology, Rega Institute, Faculty of Medicine, Katholieke Universiteit Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium
Arthritis Res Ther 12:R31. 2010..An additional aim is to investigate the role of interferon-gamma (IFN-gamma) in these processes...
- Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-gamma and counteraction by interferon-gammaHilde Kelchtermans
Laboratories of Immunobiology, Rega Institute, Faculty of Medicine, Katholieke Universiteit Leuven, Minderbroedersstraat 10, Leuven, Belgium
Arthritis Res Ther 11:R122. 2009..We took advantage of this model to analyse the mechanisms of action of IL-17 in arthritis. The role of IFN-gamma on the effector mechanisms of IL-17 in an in vitro system was also investigated...
- Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 miceLies Geboes
Katholieke Universiteit Leuven, Leuven, Belgium
Arthritis Rheum 60:390-5. 2009..To investigate the role of interleukin-22 (IL-22) in collagen-induced arthritis (CIA), an animal model of rheumatoid arthritis...
- Pulmonary inflammation in mice with collagen-induced arthritis is conditioned by complete Freund's adjuvant and regulated by endogenous IFN-γEvelien Schurgers
Laboratory of Immunobiology, Rega Institute, University of Leuven, Leuven, Belgium
Eur J Immunol 42:3223-34. 2012..We conclude that CIA in DBA/1 mice is accompanied by pulmonary inflammation. Although both disease processes are kept in check by endogenous IFN-γ, lack of strict parallelism indicates that overlap in their pathogeneses is partial...
- SPECT imaging of joint inflammation with Nanobodies targeting the macrophage mannose receptor in a mouse model for rheumatoid arthritisStéphanie Put
Laboratory of Immunobiology, Rega Institute, Katholieke Universiteit Leuven, Leuven, Belgium
J Nucl Med 54:807-14. 2013..The expression of MMR was analyzed on macrophages and osteoclasts generated in vitro and in cells obtained from various organs from mice with CIA...
- Collagen-induced arthritis as an animal model for rheumatoid arthritis: focus on interferon-γEvelien Schurgers
Laboratory of Immunobiology, Faculty of Medicine, Rega Institute, Katholieke Universiteit Leuven, Leuven, Belgium
J Interferon Cytokine Res 31:917-26. 2011....