Research Topics
| M R SchetzSummaryAffiliation: Katholieke Universiteit Leuven Country: Belgium Publications
| Collaborators
|
Detail Information
Publications
Bench-to-bedside review: metabolism and nutritionMichael P Casaer
Department of Intensive Care Medicine, University Hospital Leuven, Catholic University of Leuven, Herestraat 49, B 3000 Leuven, Belgium
Crit Care 12:222. 2008..We suggest a protocolized nutritional strategy delivering enteral nutrition whenever possible and providing at least the daily requirements of trace elements and vitamins...
Vasopressors and the kidneyMiet Schetz
Department of Intensive Care Medicine, University Hospital Gasthuisberg, Leuven, Belgium
Blood Purif 20:243-51. 2002..Administration of vasopressors to patients with oliguria should be considered in fluid-resuscitated patients with distributive shock. Whether other vasopressors offer advantages over norepinephrine requires further investigation...- Prevention of cardiac surgery-associated acute kidney injuryM Schetz
Department of Intensive Care Medicine, University of Leuven, Leuven, Belgium
Int J Artif Organs 31:179-89. 2008..No pharmacologic intervention has been adequately tested in the prevention of late CSA-AKI. A singlecenter study, including a predominance of patients after cardiac surgery, showed a decrease of kidney injury with tight glycemic control... - Tight blood glucose control is renoprotective in critically ill patientsMiet Schetz
Department of Intensive Care Medicine, University Hospital Gasthuisberg, University of Leuven, 3000 Leuven, Belgium
J Am Soc Nephrol 19:571-8. 2008..In conclusion, this secondary analysis of two large, randomized, controlled trials suggests that IIT, with a goal of achieving normoglycemia, protects the renal function of critically ill patients... - Drug dosing in continuous renal replacement therapy: general rulesMiet Schetz
Department of Intensive Care Medicine, Catholic University of Leuven, Leuven, Belgium
Curr Opin Crit Care 13:645-51. 2007..This review aims to provide general guidelines for drug dosing during continuous renal replacement therapy... - The kidney in the critically illM Schetz
Department of Intensive Care Medicine, University Hospital Gasthuisberg, Leuven, Belgium
Acta Clin Belg 62:195-207. 2007..Treatment of established AKI is largely supportive. The optimal modality for renal replacement therapy in critically-ill patients still remains a matter of debate). The majority of survivors recover renal function... - Vascular access for HD and CRRTMiet Schetz
Department of Intensive Care Medicine, University Hospital Gasthuisberg, Leuven, Belgium
Contrib Nephrol 156:275-86. 2007..In selected patients more sophisticated strategies such as the use of antibiotic/antiseptic impregnated catheters and antibiotic/antiseptic lock solutions may be useful... - Glucose control in the critically illM Schetz
Department of Intensive Care Medicine, University Hospital Gasthuisberg, Leuven, Belgium
Contrib Nephrol 144:119-31. 2004 - Diuretics in acute renal failure?Miet Schetz
Department of Intensive Care Medicine, University Hospital Gasthuisberg, Leuven, Belgium
Contrib Nephrol 144:166-81. 2004 - The Acute Dialysis Quality Initiative--part VII: fluid composition and management in CRRTMiet Schetz
Department of Intensive Care, University of Leuven, Belgium
Adv Ren Replace Ther 9:282-9. 2002..Although there is evidence that volume overload is associated with adverse outcome, there is no evidence that fluid removal per se improves outcome in critically ill patients with or without acute renal failure... - Should we use diuretics in acute renal failure?Miet Schetz
Department of Intensive Care Medicine, University Hospital Gasthuisberg, Herestraat 49, Leuven 3000, Belgium
Best Pract Res Clin Anaesthesiol 18:75-89. 2004..Possible explanations for the absence of a renoprotective effect are discussed. The evidence for a renoprotective effect of mannitol is restricted to the setting of renal transplantation... - Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic controlGreet Van den Berghe
Department of Intensive Care Medicine, Catholic University of Leuven, Belgium
Crit Care Med 31:359-66. 2003..Here we report the factors determining insulin requirements and the impact of insulin dose vs. blood glucose control on the observed outcome benefits... - Do we have reliable biochemical markers to predict the outcome of critical illness?M R Schetz
Department of Intensive Care Medicine, Catholic University of Leuven, Leuven, Belgium
Int J Artif Organs 28:1197-210. 2005..A simple biochemical predictor of ICU mortality will probably remain elusive because the processes underlying critical illness are very complex and heterogeneous. Future prognostic models will need to be far more sophisticated... 
Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled studyDirk Vlasselaers
Department of Intensive Care Medicine Paediatric Intensive Care Unit, Catholic University Leuven, Leuven, Belgium
Lancet 373:547-56. 2009..We investigated the effect of targeting age-adjusted normoglycaemia with insulin infusion in critically ill infants and children on outcome...- Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harmGreet Van den Berghe
Department of Intensive Care Medicine, University Hospital Gasthuisberg, University of Leuven, B 3000 Leuven, Belgium
Diabetes 55:3151-9. 2006..A blood glucose target <110 mg/day was most effective but also carried the highest risk of hypoglycemia... - Hyperglycemic kidney damage in an animal model of prolonged critical illnessIlse Vanhorebeek
Department of Intensive Care Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
Kidney Int 76:512-20. 2009..Normoglycemia, independent of insulinemia, protected against this damage... - Clinical review: Intensive insulin therapy in critically ill patients: NICE-SUGAR or Leuven blood glucose target?Greet Van den Berghe
Laboratory and Department of Intensive Care Medicine, Catholic University of Leuven K U Leuven, Herestraat 49, B 3000 Leuven, Belgium
J Clin Endocrinol Metab 94:3163-70. 2009..A recent large multicenter study, NICE-SUGAR, compared a similar age-normal with an intermediate glucose target and found the intermediate target superior. These results require explanation... - Clinical benefits of tight glycaemic control: effect on the kidneyJan Gunst
Department and Laboratory of Intensive Care Medicine, University of Leuven, Herestraat 49, 8 3000 Leuven, Belgium
Best Pract Res Clin Anaesthesiol 23:431-9. 2009.... - Strict blood glucose control with insulin during intensive care after cardiac surgery: impact on 4-years survival, dependency on medical care, and quality-of-lifeCatherine Ingels
Department of Intensive Care Medicine, University Hospital Gasthuisberg, Catholic University of Leuven, B-3000 Leuven, Belgium
Eur Heart J 27:2716-24. 2006.... - Effect of insulin therapy on coagulation and fibrinolysis in medical intensive care patientsLies Langouche
Department of Intensive Care Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
Crit Care Med 36:1475-80. 2008..We hypothesize that intensive insulin therapy also prevents severe coagulation abnormalities thereby contributing to less organ failure and better survival... - Drug-induced acute kidney injuryMiet Schetz
Department of Intensive Care Medicine, University Hospital, Gasthuisberg, Leuven, Belgium
Curr Opin Crit Care 11:555-65. 2005..The purpose of this review is to describe the most prevalent mechanisms of drug-induced acute kidney injury, to define the risk factors for nephrotoxicity, and to analyze the available evidence for preventive measures... - Acute renal failure in critically ill patients: a multinational, multicenter studyShigehiko Uchino
Department of Intensive Care, Austin Hospital, Melbourne, Australia
JAMA 294:813-8. 2005..87; 95% CI, 1.07-3.28; P = .03). CONCLUSION: In this multinational study, the period prevalence of ARF requiring RRT in the ICU was between 5% and 6% and was associated with a high hospital mortality rate... - External validation of severity scoring systems for acute renal failure using a multinational databaseShigehiko Uchino
Department of Intensive Care, Austin Hospital, Melbourne, Australia
Crit Care Med 33:1961-7. 2005..A large, multiple-center database might be needed to improve the discrimination and calibration of acute renal failure scoring system... - Septic acute kidney injury in critically ill patients: clinical characteristics and outcomesSean M Bagshaw
Department of Intensive Care and Department of Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
Clin J Am Soc Nephrol 2:431-9. 2007..Patients with septic AKI had an increased risk for death and longer duration of hospitalization yet showed trends toward greater renal recovery and independence from RRT... - Continuous renal replacement therapy: a worldwide practice survey. The beginning and ending supportive therapy for the kidney (B.E.S.T. kidney) investigatorsShigehiko Uchino
Jikei University School of Medicine, Intensive Care Unit, Department of Anesthesiology, Tokyo, Japan
Intensive Care Med 33:1563-70. 2007..Little information is available regarding current practice in continuous renal replacement therapy (CRRT) for the treatment of acute renal failure (ARF) and the possible clinical effect of practice variation... - Techniques for assessing and achieving fluid balance in acute renal failureRavindra L Mehta
Department of Medicine, Division of Nephrology, University of California, San Diego, California, USA
Curr Opin Crit Care 8:535-43. 2002..This article provides an overview of the concept of fluid management in the critically ill patient with acute renal failure... - Development of a clinical research agenda for acute kidney injury using an international, interdisciplinary, three-step modified Delphi processJohn A Kellum
Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Scaife Hall, Room 608, 3550 Terrace Street, Pittsburgh, PA 15261, USA
Clin J Am Soc Nephrol 3:887-94. 2008..An international, consensus-based, prioritized research agenda was sought to guide clinical and translational research in acute kidney injury... - Diuretics and mortality in acute renal failureShigehiko Uchino
Department of Intensive Care, Austin and Repatriation Medical Centre, Melbourne, Australia
Crit Care Med 32:1669-77. 2004..There is full equipoise for a randomized controlled trial of diuretics in critically ill patients with renal dysfunction...