X Sagaert

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. pmc High-grade endometrial stromal sarcoma presenting in a 28-year-old woman during pregnancy: a case report
    Frederic Amant
    Gynecologic Oncology, Leuven Cancer Institute LKI, Katholieke Universiteit Leuven, Belgium
    J Med Case Reports 4:243. 2010
  2. ncbi request reprint Classification of B-cells according to their differentiation status, their micro-anatomical localisation and their developmental lineage
    Xavier Sagaert
    Department of Morphology and Molecular Pathology KU Leuven, Aspirant FWO Flanders, Minderbroederstraat 12, 3000 Leuven, Belgium
    Immunol Lett 90:179-86. 2003
  3. doi request reprint Gastric MALT lymphoma: a model of chronic inflammation-induced tumor development
    Xavier Sagaert
    Department of Pathology, University Hospitals of K U Leuven, Minderbroederstraat 12, B 3000 Leuven, Belgium
    Nat Rev Gastroenterol Hepatol 7:336-46. 2010
  4. ncbi request reprint The dynamics of the B follicle: understanding the normal counterpart of B-cell-derived malignancies
    X Sagaert
    Department of Morphology and Molecular Pathology, University of Leuven, Leuven, Belgium
    Leukemia 21:1378-86. 2007
  5. ncbi request reprint The pathogenesis of MALT lymphomas: where do we stand?
    X Sagaert
    Department of Morphology and Molecular Pathology, University of Leuven, Leuven, Belgium
    Leukemia 21:389-96. 2007
  6. ncbi request reprint Splenic marginal zone lymphoma-like features in API2-MALT1 transgenic mice that are exposed to antigenic stimulation
    Xavier Sagaert
    Department of Morphology and Molecular Pathology, University of Leuven, Leuven, Belgium
    Haematologica 91:1693-6. 2006
  7. ncbi request reprint Forkhead box protein P1 expression in mucosa-associated lymphoid tissue lymphomas predicts poor prognosis and transformation to diffuse large B-cell lymphoma
    Xavier Sagaert
    Department of Morphology and Molecular Pathology, and the Centre for Human Genetics, Catholic University Leuven, Leuven, Belgium
    J Clin Oncol 24:2490-7. 2006
  8. ncbi request reprint MALT1 and BCL10 aberrations in MALT lymphomas and their effect on the expression of BCL10 in the tumour cells
    Xavier Sagaert
    Division of Morphology and Molecular Pathology, Katholieke Universiteit Leuven, Leuven, Belgium
    Mod Pathol 19:225-32. 2006
  9. doi request reprint Comparative expressed sequence hybridization studies of t(11;18)(q21;q21)-positive and -negative gastric MALT lymphomas reveal both unique and overlapping gene programs
    Xavier Sagaert
    Section of Morphology and Molecular Pathology, Department of Pathology, Katholieke Universiteit Leuven, Leuven, Belgium
    Mod Pathol 23:458-69. 2010
  10. doi request reprint Subclinical GvHD in non-irradiated F1 hybrids: severe lymphoid-tissue GvHD causing prolonged immune dysfunction
    B Sprangers
    Laboratory of Experimental Transplantation, University of Leuven, Leuven, Belgium
    Bone Marrow Transplant 46:586-96. 2011

Collaborators

Detail Information

Publications17

  1. pmc High-grade endometrial stromal sarcoma presenting in a 28-year-old woman during pregnancy: a case report
    Frederic Amant
    Gynecologic Oncology, Leuven Cancer Institute LKI, Katholieke Universiteit Leuven, Belgium
    J Med Case Reports 4:243. 2010
    ..To the best of our knowledge, soft tissue sarcomas have not prevously been reported as a complication during pregnancy...
  2. ncbi request reprint Classification of B-cells according to their differentiation status, their micro-anatomical localisation and their developmental lineage
    Xavier Sagaert
    Department of Morphology and Molecular Pathology KU Leuven, Aspirant FWO Flanders, Minderbroederstraat 12, 3000 Leuven, Belgium
    Immunol Lett 90:179-86. 2003
    ..In this review, we will discuss the various subsets of B-cells and point to the similarities between the various classification systems in use...
  3. doi request reprint Gastric MALT lymphoma: a model of chronic inflammation-induced tumor development
    Xavier Sagaert
    Department of Pathology, University Hospitals of K U Leuven, Minderbroederstraat 12, B 3000 Leuven, Belgium
    Nat Rev Gastroenterol Hepatol 7:336-46. 2010
    ....
  4. ncbi request reprint The dynamics of the B follicle: understanding the normal counterpart of B-cell-derived malignancies
    X Sagaert
    Department of Morphology and Molecular Pathology, University of Leuven, Leuven, Belgium
    Leukemia 21:1378-86. 2007
    ..As such, this article aims to form an excellent base for a better understanding of the normal counterpart of B-cell-derived haematological malignancies (leukemias and lymphomas)...
  5. ncbi request reprint The pathogenesis of MALT lymphomas: where do we stand?
    X Sagaert
    Department of Morphology and Molecular Pathology, University of Leuven, Leuven, Belgium
    Leukemia 21:389-96. 2007
    ..This review presents MALT lymphoma as a model of how sustained inflammation increases the risk of genotoxic insults and how these genetic events initiate oncogenesis...
  6. ncbi request reprint Splenic marginal zone lymphoma-like features in API2-MALT1 transgenic mice that are exposed to antigenic stimulation
    Xavier Sagaert
    Department of Morphology and Molecular Pathology, University of Leuven, Leuven, Belgium
    Haematologica 91:1693-6. 2006
    ..These data indicate an effect of API2-MALT1 expression on the normal immune response...
  7. ncbi request reprint Forkhead box protein P1 expression in mucosa-associated lymphoid tissue lymphomas predicts poor prognosis and transformation to diffuse large B-cell lymphoma
    Xavier Sagaert
    Department of Morphology and Molecular Pathology, and the Centre for Human Genetics, Catholic University Leuven, Leuven, Belgium
    J Clin Oncol 24:2490-7. 2006
    ..In this study, we investigated FOXP1 expression in its relationship to morphology, genetic features, and prognosis in a series of 70 MALT lymphomas...
  8. ncbi request reprint MALT1 and BCL10 aberrations in MALT lymphomas and their effect on the expression of BCL10 in the tumour cells
    Xavier Sagaert
    Division of Morphology and Molecular Pathology, Katholieke Universiteit Leuven, Leuven, Belgium
    Mod Pathol 19:225-32. 2006
    ....
  9. doi request reprint Comparative expressed sequence hybridization studies of t(11;18)(q21;q21)-positive and -negative gastric MALT lymphomas reveal both unique and overlapping gene programs
    Xavier Sagaert
    Section of Morphology and Molecular Pathology, Department of Pathology, Katholieke Universiteit Leuven, Leuven, Belgium
    Mod Pathol 23:458-69. 2010
    ....
  10. doi request reprint Subclinical GvHD in non-irradiated F1 hybrids: severe lymphoid-tissue GvHD causing prolonged immune dysfunction
    B Sprangers
    Laboratory of Experimental Transplantation, University of Leuven, Leuven, Belgium
    Bone Marrow Transplant 46:586-96. 2011
    ....
  11. doi request reprint Allogeneic bone marrow transplantation and donor lymphocyte infusion in a mouse model of irradiation-induced myelodysplastic/myeloproliferation syndrome (MD/MPS): evidence for a graft-versus-MD/MPS effect
    B Sprangers
    Laboratory of Experimental Transplantation, University of Leuven, Leuven, Belgium
    Leukemia 23:340-9. 2009
    ..However, severe DLI-induced acute graft-versus-host disease occurred, precluding a survival advantage. We present evidence of the existence of a post-alloBMT DLI-induced graft-versus-MD/MPS effect in murine irradiation-induced MD/MPS...
  12. ncbi request reprint FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrations
    I Wlodarska
    Center for Human Genetics, Katholieke Universiteit Leuven, Leuven, Belgium
    Leukemia 19:1299-305. 2005
    ..However, over-representation of the FOXP1 locus found in one additional case of DLBCL may represent another potential mechanism underlying an increased expression of this gene...
  13. ncbi request reprint Chronic wounds in a kidney transplant recipient with moderate renal impairment
    J Vanparys
    Department of Nephrology, University Hospitals Leuven, Leuven, Belgium
    Acta Clin Belg 68:128-31. 2013
    ....
  14. ncbi request reprint CTLA-4 blockade in murine bone marrow chimeras induces a host-derived antileukemic effect without graft-versus-host disease
    S Fevery
    Laboratory of Experimental Transplantation, University of Leuven, Leuven, Belgium
    Leukemia 21:1451-9. 2007
    ..Our findings reveal the potential of using CTLA-4 blockade to establish antileukemic effects after allogeneic hematopoietic stem cell transplantation, provided autoimmunity can be controlled...
  15. doi request reprint Subacute cytomegalovirus appendicitis in a renal transplant recipient
    A Posen
    Department of Internal Medicine, UZ Leuven, Leuven, Belgium
    Transpl Infect Dis 15:96-7. 2013
    ..We describe the first case, to our knowledge, documenting CMV appendicitis in a renal transplant patient, and its clinical presentation, diagnosis, and treatment...
  16. doi request reprint Posttransplant Epstein-Barr virus-associated myogenic tumors: case report and review of the literature
    B Sprangers
    Department of Nephrology, University Hospital Gasthuisberg, Leuven, Belgium
    Am J Transplant 8:253-8. 2008
    ..A case of a 51-year-old kidney transplant recipient diagnosed with EBV-SMT is reported together with a review of the literature...
  17. ncbi request reprint Selective expansion of marginal zone B cells in Emicro-API2-MALT1 mice is linked to enhanced IkappaB kinase gamma polyubiquitination
    Mathijs Baens
    Center for Human Genetics, Molecular Genetics, Flanders Interuniversity Institute for Biotechnology, Catholic University of Leuven, Leuven, Belgium
    Cancer Res 66:5270-7. 2006
    ..Taken together, these data support the hypothesis that the API2-MALT1 fusion protein can contribute to MALT lymphoma formation via increased NF-kappaB activation...