Research Topics
| M QuirynenSummaryAffiliation: Katholieke Universiteit Leuven Country: Belgium Publications
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Publications
Review of the treatment strategies for oral malodourMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology, and Maxillo facial Surgery, Faculty of Medicine, Catholic University of Leuven, Belgium
Clin Oral Investig 6:1-10. 2002..The most successful treatment involves mechanical debridement (including toothbrushing, flossing, and tongue cleaning), possibly combined with the use of an antimicrobial mouthrinse...
Impact of local and systemic factors on the incidence of oral implant failures, up to abutment connectionGhada Alsaadi
Department of Periodontology, Faculty of Medicine, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University of Leuven, Leuven, Belgium
J Clin Periodontol 34:610-7. 2007..The aim of this retrospective study was to assess the influence of systemic and local bone and intra-oral factors on the occurrence of early implant failures, i.e. up to the abutment connection...
A long-term evaluation of composite-bonded natural/resin teeth as replacement of lower incisors with terminal periodontitisM Quirynen
Department of Periodontology, Faculty of Medicine, Catholic University Leuven, Belgium
J Periodontol 70:205-12. 1999..This study assessed the longevity of composite-bonded resin/natural teeth (reinforced only with a stainless steel mesh) as replacements for periodontally lost lower incisors...
Bacterial survival rate on tooth- and interdental brushes in relation to the use of toothpasteM Quirynen
Department of Periodontology, Research Group for Microbial Adhesion, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Clin Periodontol 28:1106-14. 2001..The survival rate of cariogenic and periodontopathogenic species on toothbrushes, with and without toothpaste, and interdental brushes was presently investigated...
Effect of different chlorhexidine formulations in mouthrinses on de novo plaque formationM Quirynen
Department of Periodontology, Research Group for Microbial Adhesion, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Clin Periodontol 28:1127-36. 2001..These side effects led to the search of new formulations...
The impact of periodontal therapy and the adjunctive effect of antiseptics on breath odor-related outcome variables: a double-blind randomized studyMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Periodontol 76:705-12. 2005..g., food intake and cosmetics) and need to be calibrated among researchers worldwide. A second aim was to evaluate the reliability of saliva incubation as an in vitro indirect test for breath recording...
Microbiological and clinical outcomes and patient satisfaction for two treatment options in the edentulous lower jaw after 10 years of functionMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Catholic University of Leuven, U Z St Rafael, Capucijnenvoer 33, B 3000 Leuven, Belgium
Clin Oral Implants Res 16:277-87. 2005..Especially comparisons between fixed full prostheses (FFPs) and overdentures (ODs), or between anchoring systems for the latter are scarce...
Infectious risks for oral implants: a review of the literatureMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Catholic University Leuven, Belgium
Clin Oral Implants Res 13:1-19. 2002..Whether the susceptibility for periodontitis is related to that for peri-implantitis may vary according to the implant type and especially its surface topography...
Impact of tongue cleansers on microbial load and tasteM Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Clin Periodontol 31:506-10. 2004..Tongue cleaning has been advocated to improve oral malodor and to reduce reinfection of periodontal niches by eliminating tongue coating and/or reducing putrefaction by bacteria...
Microbial shifts after subgingival debridement and formation of bacterial resistance when combined with local or systemic antimicrobialsM Quirynen
Catholic University of Leuven, Faculty of Medicine, Research Group for Microbial Adhesion, Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Leuven, Belgium
Oral Dis 9:30-7. 2003..and occurrence of antimicrobial resistance in the subgingival flora towards antiseptics and local or systemic antibiotics and is focussed on the question: how can the outcome of periodontal therapy with/without antimicrobials be improved?..
The efficacy of amine fluoride/stannous fluoride in the suppression of morning breath odourMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Heverlee, Belgium
J Clin Periodontol 29:944-54. 2002..a control solution in the prevention of morning bad breath during an experimental period of 7 days without mechanical plaque control...
Morphology and dimensions of the mandibular jaw bone in the interforaminal region in patients requiring implants in the distal areasMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
Clin Oral Implants Res 14:280-5. 2003..The detection frequency of such variations within the lower jaw seems to advocate a profound dissection of the lingual site and, in the case of some special treatment strategies, additional cross-sectional radiography...
A salivary incubation test for evaluation of oral malodor: a pilot studyMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Periodontol 74:937-44. 2003....
Can toothpaste or a toothbrush with antibacterial tufts prevent toothbrush contamination?Marc Quirynen
Department of Periodontology, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Periodontol 74:312-22. 2003..This study examined a decontamination of toothbrushes by means of the bactericidal effect of different toothpastes or a special coating of the tufts...
Peri-implant health around screw-shaped c.p. titanium machined implants in partially edentulous patients with or without ongoing periodontitisM Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Catholic University of Leuven, Kapucijnenvoer 33, B 3000 Leuven, Belgium
Clin Oral Implants Res 12:589-94. 2001..p. titanium implants with a machined surface (Brånemark system implants) was not influenced by the progression rate of periodontal destruction around the remaining teeth within the same jaw...
Predisposing conditions for retrograde peri-implantitis, and treatment suggestionsMarc Quirynen
Department of Periodontology, Faculty of Medicine, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Katholieke Universiteit Leuven, Leuven, Belgium
Clin Oral Implants Res 16:599-608. 2005..It develops within the first months after insertion. This retrospective study aimed to find predisposing conditions for such peri-apical lesions and to evaluate treatment strategies...
A split-mouth study on periodontal and microbial parameters in children with complete unilateral cleft lip and palateM Quirynen
Department of Periodontology, Research Group for Microbial Adhesion, Catholic University of Leuven, Belgium
J Clin Periodontol 30:49-56. 2003..Such multidisciplinary treatment takes many years and demands a lot of attention to both patients' teeth and periodontium...
Periodontal health of orthodontically extruded impacted teeth. A split-mouth, long-term clinical evaluationM Quirynen
Department of Periodontology, Faculty of Medicine, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Catholic University of Leuven, Belgium
J Periodontol 71:1708-14. 2000..The purpose of this retrospective study was to examine the periodontal outcome of surgically exposed and orthodontically extruded impacted teeth compared with the spontaneously erupted contralateral teeth...
The rôle of chlorhexidine in the one-stage full-mouth disinfection treatment of patients with advanced adult periodontitis. Long-term clinical and microbiological observationsM Quirynen
Department of Periodontology, Catholic University of Leuven, Belgium
J Clin Periodontol 27:578-89. 2000..This study aims to examine the relative importance of the use of chlorhexidine in the one stage full-mouth disinfection protocol...
One stage full- versus partial-mouth disinfection in the treatment of chronic adult or generalized early-onset periodontitis. II. Long-term impact on microbial loadM Quirynen
Department of Periodontology, Faculty of Medicine, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Catholic University of Leuven, Belgium
J Periodontol 70:646-56. 1999....
Benefit of "one-stage full-mouth disinfection" is explained by disinfection and root planing within 24 hours: a randomized controlled trialMarc Quirynen
Department of Periodontology, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Clin Periodontol 33:639-47. 2006..This parallel, single blind RCT study aimed to compare several full-mouth treatment strategies with each other...
Adhesion of Porphyromonas gingivalis strains to cultured epithelial cells from patients with a history of chronic adult periodontitis or from patients less susceptible to periodontitisM Quirynen
Catholic University Leuven, Faculty of Medicine, Department of Periodontology, Research Group for Microbial Adhesion, Belgium
J Periodontol 72:626-33. 2001..gingivalis strain differences in association capacity (adhesion and internalization)...
The effect of periodontal therapy on the number of cariogenic bacteria in different intra-oral nichesM Quirynen
Department of Periodontology, Catholic University Leuven, Faculty of Medicine, School of Dentistry, Oral Medicine and Maxillo Facial Surgery, Belgium
J Clin Periodontol 26:322-7. 1999..mutans due to ecological changes within the oral cavity. The clinical consequence of this observation would be to advocate a more strict caries preventive program during initial periodontal therapy...
Dynamics of initial subgingival colonization of 'pristine' peri-implant pocketsMarc Quirynen
Department of Periodontology, Faculty of Medicine, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Catholic University Leuven, Leuven, Belgium
Clin Oral Implants Res 17:25-37. 2006..Periodontitis and peri-implantitis are linked to the presence of several key pathogens. The treatment of these infectious processes therefore involves the reduction/eradication of bacteria associated with periodontitis...
How does the timing of implant placement to extraction affect outcome?Marc Quirynen
Catholic University of Leuven, Department of Periodontology, School of Dentistry, Oral Pathology, and Maxillo facial Surgery, Leuven, Belgium
Int J Oral Maxillofac Implants 22:203-23. 2007....
The intra-oral translocation of periodontopathogens jeopardises the outcome of periodontal therapy. A review of the literatureM Quirynen
Catholic University of Leuven, Faculty of Medicine, Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Belgium
J Clin Periodontol 28:499-507. 2001..g. the mucosae, the tongue, the saliva, the periodontal pockets and all intra-oral hard surfaces) and even in the oro-pharyngeal area (e.g., the sinus and the tonsils)...
Effect of different mouthrinses on morning breathD van Steenberghe
Department of Periodontology, Oral Pathology and Maxillo-Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Belgium
J Periodontol 72:1183-91. 2001..CHX-Alc and CHX-CPC-Zn mouthrinses result in a significant reduction of the microbial load of tongue and saliva...
Marginal bone loss around implants retaining hinging mandibular overdentures, at 4-, 8- and 12-years follow-upD van Steenberghe
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Leuven, Belgium
J Clin Periodontol 28:628-33. 2001..p.) titanium implants retaining hinging mandibular overdentures...
One-stage full-mouth disinfection. Long-term microbiological results analyzed by checkerboard DNA-DNA hybridizationM De Soete
Catholic University of Leuven, Faculty of Medicine, School of Dentistry, Oral Pathology and Maxillo-Facial Surgery, Department of Periodontology, Belgium
J Periodontol 72:374-82. 2001..CONCLUSIONS: The OSFM disinfection results in supplementary reductions of periodontal pathogens even after 8 months in the treatment of patients with advanced or early-onset periodontitis...
Biologic outcome of single-implant restorations as tooth replacements: a long-term follow-up studyI Naert
Department of Prosthetic Dentistry, Catholic University of Leuven, Kapucijnenvoer 7, B 3000 Leuven, Belgium
Clin Implant Dent Relat Res 2:209-18. 2000..The replacement of a single tooth or several teeth by means of single-implant restorations is an increasingly used method that needs long-term validation...
Increase in cariogenic bacteria after initial periodontal therapyM De Soete
Department of Periodontology, Faculty of Medicine, Catholic University of Leuven, Belgium
J Dent Res 84:48-53. 2005..These observations were similar for all sample locations. The periopathogens decreased in all groups. This finding confirms the abovementioned hypothesis and indicates a need for caries prophylactic regimens...
The immediate rehabilitation by means of a ready-made final fixed prosthesis in the edentulous mandible: a 1-year follow-up study on 50 consecutive patientsD van Steenberghe
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
Clin Oral Implants Res 15:360-5. 2004..The survival rate is, however, lower than for a staged approach...
Guiding periodontal pocket recolonization: a proof of conceptW Teughels
Catholic University Leuven, Research Group for Microbial Adhesion, Department of Periodontology, Kapucijnenvoer 7, 3000 Leuven, Belgium
J Dent Res 86:1078-82. 2007..The study confirmed the hypothesis and provides a proof of concept for a guided pocket recolonization (GPR) approach in the treatment of periodontitis...
Viability of cultured periodontal pocket epithelium cells and Porphyromonas gingivalis associationK Dierickx
Catholic University of Leuven, Faculty of Medicine, School of Dentistry, Oral Pathology and Maxillo-Facial Surgery, Department of Periodontology, Kapucijnenvoer 7, B-3000 Leuven, Belgium
J Clin Periodontol 29:987-96. 2002..As a result, the damage they cause to the host cell seems to occur faster than occurs in encapsulated strains. As such, cell death can be seen as the end-result of bacterial association...
Interference with Aggregatibacter actinomycetemcomitans: colonization of epithelial cells under hydrodynamic conditionsI Sliepen
Research Group for Microbial Adhesion, Department of Periodontology, Catholic University Leuven, Leuven, Belgium
Oral Microbiol Immunol 24:390-5. 2009..The aim of this study was to test this hypothesis on soft surfaces in vitro, taking into account the hydrodynamic forces continuously present in vivo...
Evaluation of factors influencing the marginal bone stability around implants in the treatment of partial edentulismI Naert
Department of Prosthetic Dentistry, School of Dentistry, Catholic University of Leuven, Leuven, Belgium Ignace
Clin Implant Dent Relat Res 3:30-8. 2001..The original protocol of Brånemark to achieve predictable osseointegration for oral implants has substantially been modified. One may question whether results are influenced by those modifications, especially for the long-term prognosis...
Killing of anaerobic pathogens by predatory bacteriaM Van Essche
Department of Periodontology, Catholic University Leuven, Leuven, Belgium
Mol Oral Microbiol 26:52-61. 2011..This finding makes the case for continued study of the potential for BALOs to combat periodontal pathogens...
Long-term, retrospective evaluation (implant and patient-centred outcome) of the two-implants-supported overdenture in the mandible. Part 1: survival rateM Vercruyssen
Department of Periodontology, Catholic University Leuven, Leuven, Belgium
Clin Oral Implants Res 21:357-65. 2010..This retrospective analysis evaluated the long-term outcome of two implants supporting an overdenture in the mandible, as well as the significance of some confounding factors (smoking, implant length, bone quality)...
The safety and efficacy of a powered toothbrush on soft tissues in patients with implant-supported fixed prosthesesB Vandekerckhove
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo-Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
Clin Oral Investig 8:206-10. 2004..It is concluded that the powered toothbrush investigated is effective, safe and comfortable for patients rehabilitated by means of oral implant-supported prostheses...
Microbial interactions influence inflammatory host cell responsesI Sliepen
Catholic University Leuven, Research Group for Microbial Adhesion, Department of Periodontology, Kapucijnenvoer 7, 3000 Leuven, Belgium
J Dent Res 88:1026-30. 2009..These results show that bacterial species can influence the inflammatory responses of host cells triggered by infection with A. actinomycetemcomitans...
RCT comparing minimally with moderately rough implants. Part 2: microbial observationsM Quirynen
Department of Periodontology, Catholic University Leuven, Leuven, Belgium
Clin Oral Implants Res 23:625-34. 2012..This randomized controlled trial (RCT), with split-mouth design, examined whether this increased surface roughness influenced the initial subgingival plaque formation...
Adhesion of Porphyromonas gingivalis to cultured pocket epithelium: mono- and multi-layeredW Papaioannou
Faculty of Medicine, Department of Periodontology, Research Group for Microbial Adhesion, Catholic University Leuven, Leuven, Belgium
Clin Oral Investig 7:162-6. 2003..Mono-layer cultures, which are simpler to obtain, seem to be less precise. The importance of cell differentiation on bacterial adhesion needs more attention...
Radiographic detection of artificial intra-bony defects in the edentulous areaN Van Assche
Department of Periodontology, Catholic University Leuven, Kapucijnenvoer 33, Leuven 3000, Belgium
Clin Oral Implants Res 20:273-9. 2009..Since intra-bony pathologies might jeopardize implant outcome, their preoperative detection is crucial...
Accuracy assessment of computer-assisted flapless implant placement in partial edentulismN Van Assche
Department of Periodontology, Faculty of Medicine, Catholic University Leuven, Leuven, Belgium
J Clin Periodontol 37:398-403. 2010..To assess the accuracy of implants placed flapless by a stereolithographic template in partially edentulous patients...
Bacteria interfere with A. actinomycetemcomitans colonizationW Teughels
Catholic University Leuven, Research Group for Microbial Adhesion, Department of Periodontology, Leuven, Belgium
J Dent Res 86:611-7. 2007..actinomycetemcomitans colonization of epithelial cells in vitro, and demonstrated the potential beneficial effects of S. mitis, S. salivarius, and S. sanguinis...
Effect of mouthrinses on Aggregatibacter actinomycetemcomitans biofilms in a hydrodynamic modelIsabelle Sliepen
Research Group for Microbial Adhesion, Department of Periodontology, Catholic University Leuven, Kapucijnenvoer 7, 3000 Leuven, Belgium
Clin Oral Investig 14:241-50. 2010..The total amount of bacteria was not significantly affected by Listerine and Meridol...
A 0.05% cetyl pyridinium chloride/0.05% chlorhexidine mouth rinse during maintenance phase after initial periodontal therapyMarc Quirynen
Department of Periodontology, Oral Pathology and Maxillo-Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Clin Periodontol 32:390-400. 2005..CONCLUSIONS: The results of this study demonstrated the potential of a new CHX 0.05%+CPC 0.05% non-alcoholic formulation as an effective antiplaque agent for long-term use with reduced subjective side effects...
RCT comparing minimally with moderately rough implants. Part 1: clinical observationsN Van Assche
Research Group for Microbial Adhesion Leuven, Department of Periodontology, Catholic University Leuven, Leuven, Belgium
Clin Oral Implants Res 23:617-24. 2012..This 1-year prospective RCT compared the outcome of minimally (turned) and moderately rough (TiUnite) implant surfaces...
Absorbed doses from spiral CT and conventional spiral tomography: a phantom vs. cadaver studyC Bou Serhal
Department of Periodontology, Oral Imaging Cluster, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Kapucijnenvoer 7, 3000 Leuven, Belgium
Clin Oral Implants Res 12:473-8. 2001..However, when multiple tomographic cuts are required, a spiral CT examination can replace a series of conventional examinations, especially in cases such as the rehabilitation of an edentulous upper jaw or a more complex surgery...
Bactericidal effect of Nd:YAG laser irradiation on some endodontic pathogens ex vivoL Bergmans
Department of Conservative Dentistry, Leuven BIOMAT Research Cluster, Leuven, Belgium
Int Endod J 39:547-57. 2006..To define the role of neodymium:yttrium-aluminum-garnet (Nd:YAG) lasers in root canal disinfection along with a minimally invasive treatment concept...
Live/dead real-time polymerase chain reaction to assess new therapies against dental plaque-related pathologiesG Loozen
Department of Periodontology, Catholic University of Leuven, Leuven, Belgium
Mol Oral Microbiol 26:253-61. 2011..The developed assay will potentially be useful for assessing bacterial loads remaining after disinfection protocols without interference by non-viable bacteria...
Accuracy of implant placement based on pre-surgical planning of three-dimensional cone-beam images: a pilot studyN Van Assche
Department of Periodontology, Faculty of Medicine, Catholic University Leuven, Leuven, Belgium
J Clin Periodontol 34:816-21. 2007..To evaluate the precision of transfer of a computer-based three-dimensional (3D) planning, using re-formatted cone-beam images, for oral implant placement in partially edentulous jaws...
Localisation of the mandibular canal using conventional spiral tomography: a human cadaver studyC Bou Serhal
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University of Leuven, Leuven, Belgium
Clin Oral Implants Res 12:230-6. 2001....
Freestanding and tooth-implant connected prostheses in the treatment of partially edentulous patients Part II: An up to 15-years radiographic evaluationI E Naert
Department of Prosthetic Dentistry BIOMAT Research Group, Catholic University of Leuven, Belgium
Clin Oral Implants Res 12:245-51. 2001..However, the clinical significance of greater bone loss in rigid versus non-rigid connections might outweigh the annoying phenomenon of tooth intrusion in the case of non-rigid tooth connection, when connection is considered...
Successful outcome of splinted implants supporting a 'planned' maxillary overdenture: a retrospective evaluation and comparison with fixed full dental prosthesesA Sanna
Department of Periodontology, Catholic University Leuven, Leuven, Belgium
Clin Oral Implants Res 20:406-13. 2009..This retrospective analysis evaluated the peri-implant parameters of implants supporting a 'planned' overdenture in the maxilla, and compared these data with those of an age-matched control group, with a fixed full dental prosthesis...
Colonization of hard and soft surfaces by Aggregatibacter actinomycetemcomitans under hydrodynamic conditionsI Sliepen
Research Group for Microbial Adhesion, Department of Periodontology, Catholic University Leuven, Leuven, Belgium
Oral Microbiol Immunol 23:498-504. 2008..For extrapolation purposes the comparability between the dynamics of colonization on hard vs. soft surfaces needs to be evaluated...
Human cytomegalovirus enhances A. actinomycetemcomitans adherence to cellsW Teughels
Catholic University Leuven, Research Group for Microbial Adhesion, Department of Periodontology, Kapucijnenvoer 7, 3000 Leuven, Belgium
J Dent Res 86:175-80. 2007..The results confirmed our hypothesis that the adherence of Actinobacillus actinomycetemcomitans is influenced by hCMV in vitro...
Effect of photo-activated disinfection on endodontic pathogens ex vivoL Bergmans
BIOMAT Research Cluster, Catholic University of Leuven, Leuven, Belgium
Int Endod J 41:227-39. 2008..To test the hypothesis that photo-activated disinfection (PAD) has a bactericidal effect on pathogens inoculated in root canals, with emphasis on biofilm formation/destruction...
The influence of plaque and/or excessive loading on marginal soft and hard tissue reactions around Brånemark implants: a review of literature and experienceE De Smet
Department of Prosthetic Dentistry, Catholic University of Leuven, Faculty of Medicine, Belgium
Int J Periodontics Restorative Dent 21:381-93. 2001..Some clinical observations support this hypothesis...
Aggregatibacter actinomycetemcomitans adhesion inhibited in a flow cellI Sliepen
Catholic University Leuven, Research Group for Microbial Adhesion, Department of Periodontology, Leuven, Belgium
Oral Microbiol Immunol 23:520-4. 2008..This study addressed the hypothesis that a streptococcal biofilm influences the hard tissue colonization by the periodontopathogen Aggregatibacter actinomycetemcomitans under hydrodynamic conditions...
Sleeping vs. loaded implants, long-term observations via a retrospective analysisK Marcelis
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Catholic University Leuven, Kapucijnenvoer 33, B 3000, Leuven, Belgium
Clin Oral Implants Res 23:1118-22. 2012..Several theories have been presented to explain initial and secondary marginal bone loss around dental implants (e.g. microbial load, adverse loading, microbial leakage, compromised healing/adaptation of host-implant interface)...
Bdellovibrio bacteriovorus attacks Aggregatibacter actinomycetemcomitansM Van Essche
Catholic University Leuven, Department of Periodontology, Kapucijnenvoer 7, 3000 Leuven, Belgium
J Dent Res 88:182-6. 2009..The in vitro results show that B. bacteriovorus can attack, prey on, and kill A. actinomycetemcomitans and suggest a potential for B. bacteriovorus as a living antibiotic for the prevention and treatment of periodontitis...
Initial subgingival colonization of 'pristine' pocketsM Quirynen
Department of Periodontology, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Kapucijnenvoer 7, B 3000 Leuven, Belgium
J Dent Res 84:340-4. 2005..Analysis of these data demonstrated that, even with the supragingival environment as the single source for colonizing bacteria, a complex subgingival microbiota can develop within 1 wk...
Perioperative validation of localisation of the mental foramenC Bou Serhal
Department of Periodontology, Oral Imaging Center, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Kapucijnenvoer7, 3000 Leuven, Belgium
Dentomaxillofac Radiol 31:39-43. 2002..05). In general, distances were overestimated on the panoramic radiographs. CONCLUSIONS: Cross-sectional imaging techniques are recommended for the pre-operative planning of implants in the posterior mandible...
Topical antiseptics and antibiotics in the initial therapy of chronic adult periodontitis: microbiological aspectsMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Belgium
Periodontol 2000 28:72-90. 2002
Relationship between cortical bone thickness or computerized tomography-derived bone density values and implant stabilityJoe Merheb
Department of Periodontology, Catholic University Leuven, Belgium
Clin Oral Implants Res 21:612-7. 2010..To explore the relationship between primary implant stability and different parameters related to implant or bone properties...
Periodontal parameters around implants anchoring orthodontic appliances: a series of case reportsLiene Molly
Department of Periodontology, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Periodontol 75:176-81. 2004..2 mm (SD: 1.2) below I/A interface after completion of the orthodonic treatment. CONCLUSION: No significant marginal bone loss was present. Using implants during orthodontics can result in an easier and more predictable treatment...
Impact of local and systemic factors on the incidence of failures up to abutment connection with modified surface oral implantsGhada Alsaadi
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Clin Periodontol 35:51-7. 2008..This study aimed to assess the influence of systemic and local bone and intra-oral factors on the occurrence of early TiUnite implant failures...
Long-term, retrospective evaluation (implant and patient-centred outcome) of the two-implant-supported overdenture in the mandible. Part 2: marginal bone lossM Vercruyssen
Department of Periodontology, Catholic University Leuven, Kapucijnenvoer, Leuven, Belgium
Clin Oral Implants Res 21:466-72. 2010....
Dental abnormalities, bone graft quality, and periodontal conditions in patients with unilateral cleft lip and palate at different phases of orthodontic treatmentG Dewinter
Department of Orthodontics, Faculty of Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
Cleft Palate Craniofac J 40:343-50. 2003..The children, who had not yet started treatment, also showed enough bone support and no periodontal problems of the teeth besides the cleft. Early secondary bone grafting seems to give optimal periodontal results...
Detection of odorous compounds in breathS Van den Velde
Department of Periodontology, Catholic University of Leuven, Leuven, Belgium
J Dent Res 88:285-9. 2009..We concluded that hydrogen sulfide, methyl mercaptan and, to a much lesser extent, dimethyl sulfide, di- and trisulfide can contribute to oral malodor. The role of other compounds, such as amines and organic acids, seems insignificant...
Appearance, location, course, and morphology of the mandibular incisive canal: an assessment on spiral CT scanR Jacobs
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Faculty of Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
Dentomaxillofac Radiol 31:322-7. 2002..To assess the appearance, location, and course of the incisive canal as compared to other anatomical landmarks on spiral CT of the mandible...
The nasopalatine canal revisited using 2D and 3D CT imagingN Mraiwa
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven, Belgium
Dentomaxillofac Radiol 33:396-402. 2004..Cross-sectional imaging may be advocated to determine canal morphology and dimensions and to assess anterior bone width for potential implant placement buccally to the canal...
Bone augmentation by means of a stiff occlusive titanium barrierDaniel Van Steenberghe
Department of Periodontology, School of Dentistry, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
Clin Oral Implants Res 14:63-71. 2003..Both animal and clinical data demonstrate that guided bone neogenesis under a subperiosteally placed titanium barrier can reach large volumes...
Comparison between jaw bone augmentation by means of a stiff occlusive titanium membrane or an autologous hip graft: a retrospective clinical assessmentLiene Molly
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillo-Facial Surgery, Faculty of Medicine, Catholic University of Leuven, Kapucijnenvoer 7, B-3000 Leuven, Belgium
Clin Oral Implants Res 17:481-7. 2006..This technique could offer improvement if membrane exposure can be avoided...
Clinical reliability of non-organoleptic oral malodour measurementsBetty Vandekerckhove
Department of Periodontology, Catholic University of Leuven, Leuven BE 3000, Belgium
J Clin Periodontol 36:964-9. 2009..Measurement of volatile sulphur compounds (VSC) by portable sulphur monitors (Halimeter, OralChroma) is a common practice for diagnosis of oral malodour. In this study, the clinical value of these devices was examined...
Bone formation following implantation of bone biomaterials into extraction sitesLiene Molly
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven, Kapucijnenvoer7, Leuven, Belgium
J Periodontol 79:1108-15. 2008....
Impact of local and systemic factors on the incidence of late oral implant lossGhada Alsaadi
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
Clin Oral Implants Res 19:670-6. 2008..This retrospective study was set to assess the influence of systemic and local bone and intra-oral factors on the occurrence of implant loss from abutment connection up to 2 years...
Impact of antiseptics on one-stage, full-mouth disinfectionMarc Quirynen
J Clin Periodontol 33:49-52. 2006
Impact of supportive periodontal therapy and implant surface roughness on implant outcome in patients with a history of periodontitisMarc Quirynen
Department of Periodontology, Catholic University Leuven, Leuven, Belgium
J Clin Periodontol 34:805-15. 2007....
Characteristics of 2000 patients who visited a halitosis clinicMarc Quirynen
Department of Periodontology, Catholic University of Leuven, Kapucijnenvoer 33, Leuven BE 3000, Belgium
J Clin Periodontol 36:970-5. 2009..The aim of this paper was to analyse the aetiology and characteristics of 2000 patients who visited a multidisciplinary bad breath clinic in Leuven, Belgium and to correlate organoleptic ratings with portable device measurements...
A biomechanical assessment of the relation between the oral implant stability at insertion and subjective bone quality assessmentGhada Alsaadi
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven, Leuven, Belgium
J Clin Periodontol 34:359-66. 2007..The study was set to evaluate the validity of subjective jaw bone quality assessment...
The importance of implant surface characteristics in the replacement of failed implantsGhada Alsaadi
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University of Leuven, Belgium
Int J Oral Maxillofac Implants 21:270-4. 2006..CONCLUSION: An improved implant surface such as TiUnite may offer a better prognosis when a failed implant has to be replaced at the same site...
Appearance of the mandibular incisive canal on panoramic radiographsR Jacobs
Oral Imaging Center, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Katholieke Universiteit Leuven, Kapucijnenvoer 7, 3000, Leuven, Belgium
Surg Radiol Anat 26:329-33. 2004..To verify its existence for preoperative planning purposes, cross-sectional imaging modalities (HR-CT or spiral tomography) should be preferred...
Microscopic observation of bacteria: review highlighting the use of environmental SEML Bergmans
Leuven BIOMAT Research Cluster, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Catholic University of Leuven, Leuven, Belgium
Int Endod J 38:775-88. 2005..The paper concludes with a discussion on the possible use of ESEM for testing endodontic treatment modalities under environmental conditions in situ...
Tolerance within a surgical guideN Van Assche
Department of Periodontology, Catholic University Leuven, Kapucijnenvoer 33, 3000 Leuven, Belgium
Clin Oral Implants Res 21:455-8. 2010..Recently, guided surgery has been introduced and several papers verified its accuracy...
Influence of genetic background on transformation and expression of Green Fluorescent Protein in Actinobacillus actinomycetemcomitansW Teughels
Catholic University Leuven, Department of Periodontology, Leuven, Belgium
Oral Microbiol Immunol 20:274-81. 2005..actinomycetemcomitans strains. The influence of the plasmid vector, serotype, and phenotype were the major factors taken into consideration...
Management of oral malodourM Quirynen
Catholic University Leuven, Faculty of Medicine, Leuven, Belgium
J Clin Periodontol 30:17-8. 2003..The majority of studies involving mouthwashes have investigated chlorhexidine and essential oil mouthwashes, although comparative studies are sparse...
[Non plaque-related gingivitis]D van Steenberghe
Afdeling Parodontologie van de School voor Tandheelkunde, Mondziekte en Kaakchirurgie, Faculteit Geneeskunde, van de Katholieke Universiteit Leuven, Belgie
Ned Tijdschr Tandheelkd 109:419-21. 2002..This paper illustrates the most frequent causes, not only encountered by the periodontologist, but also by the general practitioner, such as erosive lichen planus, herpes, Candida and radiotherapy...
Microbial adhesion on different bracket types in vitroJan van Gastel
Department of Orthodontics, Catholic University, Leuven, Belgium
Angle Orthod 79:915-21. 2009..To test the hypothesis that there are differences in total bacterial counts and capacity for biofilm formation between seven different bracket types...
Impact of systemic diseases and medication on osseointegrationDaniel Van Steenberghe
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Belgium
Periodontol 2000 33:163-71. 2003
Microbiologically compromised patients and impact on oral implantsMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Belgium
Periodontol 2000 33:119-28. 2003
An infected jawbone site compromising successful osseointegrationMarc Quirynen
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Belgium
Periodontol 2000 33:129-44. 2003
Influence of nicotine and cotinine on epithelial colonization by periodontopathogensWim Teughels
Department of Periodontology, Catholic University Leuven, Leuven, Belgium
J Periodontol 76:1315-22. 2005..Whether these findings that support the hypothesis of an increased patient susceptibility for bacterial adhesion to epithelial cells in smokers are clinically relevant remains to be proven...
Clinical examples of what can be achieved with osseointegration in anatomically severely compromised patientsDaniel Van Steenberghe
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Belgium
Periodontol 2000 33:90-104. 2003
Do periodontopathogens disappear after full-mouth tooth extraction?Nele Van Assche
Department of Periodontology, Catholic University Leuven, Leuven, Belgium
J Clin Periodontol 36:1043-7. 2009..To monitor the intra-oral microbiological changes after full-mouth extraction using quantitative polymerase chain reaction (qPCR)...
Adhesion of Porphyromonas gingivalis serotypes to pocket epitheliumKurt Dierickx
Catholic University of Leuven, Faculty of Medicine, School of Dentistry, Oral Pathology and Maxillo Facial Surgery, Department of Periodontology, Leuven, Belgium
J Periodontol 74:844-8. 2003..Different capsular antigens of P. gingivalis have been identified (K-serotyping). These P. gingivalis capsular types show differences in adhesion capacity to human cell lines or to cells cultured on a feeder layer or stromal equivalent...
The relative impact of local and endogenous patient-related factors on implant failure up to the abutment stageDaniel Van Steenberghe
Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Leuven, Belgium
Clin Oral Implants Res 13:617-22. 2002..Radiotherapy, limited bone volume and claustrophobia, which led to breaching the strict preoperative rules of asepsis, appeared to be the most relevant local factors for early implant failures...
Histological, histomorphometrical, and radiological evaluation of an experimental implant design with a high insertion torqueJoke Duyck
Department of Prosthetic Dentistry, BIOMAT Research Group, Katholieke Universiteit Leuven, Leuven, Belgium
Clin Oral Implants Res 21:877-84. 2010..The aim of this study was to compare bone behaviour around an experimental implant design with a high insertion torque with the Astra-Tech implant (control)...
Biologic outcome of implant-supported restorations in the treatment of partial edentulism. Part 2: a longitudinal radiographic studyIgnace Naert
Department of Prosthetic Dentistry, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University Leuven, Belgium
Clin Oral Implants Res 13:390-5. 2002..Based on marginal bone height maintenance, the excellent prognosis of the presently used implants to support restorations in the treatment of partial edentulism was confirmed...
Biologic outcome of implant-supported restorations in the treatment of partial edentulism. part I: a longitudinal clinical evaluationIgnace Naert
Department of Prosthetic Dentistry, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Faculty of Medicine, Catholic University Leuven, Belgium
Clin Oral Implants Res 13:381-9. 2002..The idea of not splinting the implants in a fixed partial prosthesis is promising but needs replication before accepting it...
Research Grants
- Guided Pocket Recolonization (GPR) in PeriodontitisMarc Quirynen; Fiscal Year: 2004..Clinical data will be collected after 2, 4, 6, 8 and 12 weeks. The results should indicate the possible role for commensal organisms in periodontal disease and subgingival biofilm formation. ..
