Marleen M R Petit

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. pmc The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus
    Marleen M R Petit
    Laboratory for Molecular Oncology, Department of Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology VIB, Herestraat 49, B 3000 Leuven, Belgium
    BMC Cell Biol 6:1. 2005
  2. ncbi The tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteins
    Marleen M R Petit
    Laboratory for Molecular Oncology, Department of Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology VIB, Herestraat 49, B 3000 Leuven, Belgium
    FEBS Lett 579:5061-8. 2005
  3. ncbi HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB
    Isabelle Cleynen
    Department of Human Genetics, Flanders Interuniversity Institute for Biotechnology, University of Leuven, Herestraat 49, Box 602, B 3000 Leuven, Belgium
    Mol Cancer Res 5:363-72. 2007
  4. ncbi The focal adhesion and nuclear targeting capacity of the LIM-containing lipoma-preferred partner (LPP) protein
    Marleen M R Petit
    Laboratory for Molecular Oncology, Department of Human Genetics, University of Leuven K U Leuven and Flanders Interuniversity Institute for Biotechnology VIB, Herestraat 49, Belgium
    J Biol Chem 278:2157-68. 2003
  5. doi Targeted disruption of the mouse Lipoma Preferred Partner gene
    Hilke B V K Vervenne
    Laboratory for Molecular Oncology, Department of Human Genetics, Herestraat 49, Box 602, K U Leuven, Leuven, Belgium
    Biochem Biophys Res Commun 379:368-73. 2009
  6. ncbi Transactivation functions of the tumor-specific HMGA2/LPP fusion protein are augmented by wild-type HMGA2
    Koen R M O Crombez
    Department of Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology, Herestraat 49 bus 602, B 3000 Leuven, Belgium
    Mol Cancer Res 3:63-70. 2005
  7. doi Lpp is involved in Wnt/PCP signaling and acts together with Scrib to mediate convergence and extension movements during zebrafish gastrulation
    Hilke B V K Vervenne
    Laboratory for Molecular Oncology, Department of Human Genetics, K U Leuven, Leuven, Belgium
    Dev Biol 320:267-77. 2008
  8. ncbi Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2
    Jan R Brants
    Laboratory for Molecular Oncology, Department of Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology VIB, Herestraat 49, B 3000 Leuven, Belgium
    FEBS Lett 569:277-83. 2004
  9. pmc The LIM domain protein LPP is a coactivator for the ETS domain transcription factor PEA3
    Baoqiang Guo
    Faculty of Life Sciences, University of Manchester, Michael Smith Bldg, Oxford Road, Manchester M13 9PT, United Kingdom
    Mol Cell Biol 26:4529-38. 2006
  10. doi Smooth muscle expression of lipoma preferred partner is mediated by an alternative intronic promoter that is regulated by serum response factor/myocardin
    Marleen M R Petit
    Wallenberg Laboratory, Sahlgrenska University Hospital, Goteborg, Sweden
    Circ Res 103:61-9. 2008

Collaborators

Detail Information

Publications10

  1. pmc The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus
    Marleen M R Petit
    Laboratory for Molecular Oncology, Department of Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology VIB, Herestraat 49, B 3000 Leuven, Belgium
    BMC Cell Biol 6:1. 2005
    ..LPP has three LIM domains (zinc-finger protein interaction domains) at its carboxy-terminus, which are preceded by a proline-rich pre-LIM region containing a number of protein interaction domains...
  2. ncbi The tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteins
    Marleen M R Petit
    Laboratory for Molecular Oncology, Department of Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology VIB, Herestraat 49, B 3000 Leuven, Belgium
    FEBS Lett 579:5061-8. 2005
    ..The binding between two of zyxin's family members and Scrib links Scrib to a communication pathway between cell-cell contacts and the nucleus, and implicates these zyxin family members in Scrib-associated functions...
  3. ncbi HMGA2 regulates transcription of the Imp2 gene via an intronic regulatory element in cooperation with nuclear factor-kappaB
    Isabelle Cleynen
    Department of Human Genetics, Flanders Interuniversity Institute for Biotechnology, University of Leuven, Herestraat 49, Box 602, B 3000 Leuven, Belgium
    Mol Cancer Res 5:363-72. 2007
    ..Finally, we provide evidence that there is a strong and statistically significant correlation between HMGA2 and IMP2 gene expression in human liposarcomas...
  4. ncbi The focal adhesion and nuclear targeting capacity of the LIM-containing lipoma-preferred partner (LPP) protein
    Marleen M R Petit
    Laboratory for Molecular Oncology, Department of Human Genetics, University of Leuven K U Leuven and Flanders Interuniversity Institute for Biotechnology VIB, Herestraat 49, Belgium
    J Biol Chem 278:2157-68. 2003
    ..Our studies have defined novel functional domains in the LPP protein...
  5. doi Targeted disruption of the mouse Lipoma Preferred Partner gene
    Hilke B V K Vervenne
    Laboratory for Molecular Oncology, Department of Human Genetics, Herestraat 49, Box 602, K U Leuven, Leuven, Belgium
    Biochem Biophys Res Commun 379:368-73. 2009
    ..Finally, we discovered a short nuclear form of Lpp, expressed mainly in testis via an alternative promoter...
  6. ncbi Transactivation functions of the tumor-specific HMGA2/LPP fusion protein are augmented by wild-type HMGA2
    Koen R M O Crombez
    Department of Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology, Herestraat 49 bus 602, B 3000 Leuven, Belgium
    Mol Cancer Res 3:63-70. 2005
    ..These results support the concept that the transactivation functions of the novel HMGA2/LPP transcription factor contribute to lipomagenesis...
  7. doi Lpp is involved in Wnt/PCP signaling and acts together with Scrib to mediate convergence and extension movements during zebrafish gastrulation
    Hilke B V K Vervenne
    Laboratory for Molecular Oncology, Department of Human Genetics, K U Leuven, Leuven, Belgium
    Dev Biol 320:267-77. 2008
    ..Finally, we demonstrate that Lpp interacts with the PCP protein Scrib in zebrafish, and that Lpp and Scrib cooperate for the mediation of C&E...
  8. ncbi Differential regulation of the insulin-like growth factor II mRNA-binding protein genes by architectural transcription factor HMGA2
    Jan R Brants
    Laboratory for Molecular Oncology, Department of Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology VIB, Herestraat 49, B 3000 Leuven, Belgium
    FEBS Lett 569:277-83. 2004
    ..Our results clearly indicate that HMGA2 differentially regulates expression of IMP family members during embryogenesis...
  9. pmc The LIM domain protein LPP is a coactivator for the ETS domain transcription factor PEA3
    Baoqiang Guo
    Faculty of Life Sciences, University of Manchester, Michael Smith Bldg, Oxford Road, Manchester M13 9PT, United Kingdom
    Mol Cell Biol 26:4529-38. 2006
    ..As LPP continually shuttles between the cell periphery and the nucleus, it represents a potential novel link between cell surface events and changes in gene expression...
  10. doi Smooth muscle expression of lipoma preferred partner is mediated by an alternative intronic promoter that is regulated by serum response factor/myocardin
    Marleen M R Petit
    Wallenberg Laboratory, Sahlgrenska University Hospital, Goteborg, Sweden
    Circ Res 103:61-9. 2008
    ..Collectively, our data demonstrate that expression of LPP in smooth muscle is mediated by an alternative promoter that is regulated by SRF/myocardin...