E Lesaffre

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. ncbi request reprint A note on the number needed to treat
    E Lesaffre
    Biostatistical Centre, Leuven, Belgium
    Control Clin Trials 20:439-47. 1999
  2. ncbi request reprint Analysis of caries experience taking inter-observer bias and variability into account
    E Lesaffre
    Biostatistical Centre, Catholic University Leuven, Kapucijnenvoer 35, B 3000 Leuven, Belgium
    J Dent Res 83:951-5. 2004
  3. ncbi request reprint A note on non-parametric ANCOVA for covariate adjustment in randomized clinical trials
    Emmanuel Lesaffre
    Biostatistical Centre, University of Leuven, Belgium
    Stat Med 22:3583-96. 2003
  4. ncbi request reprint A retrospective analysis of the effect of noncompliance on time to first major adverse cardiac event in LIPS
    Emmanuel Lesaffre
    Biostatistical Centre, Katholieke Universiteit Leuven, Leuven, Belgium
    Clin Ther 25:2431-47. 2003
  5. ncbi request reprint On the variability of covariate adjustment. experience with Koch's method for evaluating the absolute difference in proportions in randomized clinical trials
    Emmanuel Lesaffre
    Biostatistical Centre, Catholic University of Leuven, U Z St Rafael, Kapucijnenvoer 35, 3000 Leuven, Belgium
    Control Clin Trials 23:127-42. 2002
  6. doi request reprint Factors that influence data quality in caries experience detection: a multilevel modeling approach
    T Mutsvari
    L BioStat, Leuven, Belgium
    Caries Res 44:438-44. 2010
  7. ncbi request reprint Assessment of caries experience in epidemiological surveys: a review
    J O Agbaje
    Department of Conservative Dentistry, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University of Leuven, Belgium
    Community Dent Health 29:14-9. 2012
  8. ncbi request reprint Modelling bivariate ordinal responses smoothly with examples from ophthalmology and genetics
    R Bustami
    Biostatistical Center, Katholieke Universiteit Leuven, Kapucijnenvoer 35, B-3000 Leuven, Belgium
    Stat Med 20:1825-42. 2001
  9. ncbi request reprint Sensitivity analysis for nonrandom dropout: a local influence approach
    G Verbeke
    Biostatistical Centre, Katholieke Universiteit Leuven, Belgium
    Biometrics 57:7-14. 2001
  10. ncbi request reprint Effect of caries experience in primary molars on cavity formation in the adjacent permanent first molar
    R Leroy
    School of Dentistry, Oral Pathology, Maxillofacial Surgery, Leuven, Belgium
    Caries Res 39:342-9. 2005

Collaborators

Detail Information

Publications56

  1. ncbi request reprint A note on the number needed to treat
    E Lesaffre
    Biostatistical Centre, Leuven, Belgium
    Control Clin Trials 20:439-47. 1999
    ..The calculations are illustrated using data from anti-epileptic trials...
  2. ncbi request reprint Analysis of caries experience taking inter-observer bias and variability into account
    E Lesaffre
    Biostatistical Centre, Catholic University Leuven, Kapucijnenvoer 35, B 3000 Leuven, Belgium
    J Dent Res 83:951-5. 2004
    ..The proposed method offers an opportunity to refine existing analytical approaches and is relevant to any health outcome study...
  3. ncbi request reprint A note on non-parametric ANCOVA for covariate adjustment in randomized clinical trials
    Emmanuel Lesaffre
    Biostatistical Centre, University of Leuven, Belgium
    Stat Med 22:3583-96. 2003
    ..Med. 1998; 17: 1863-1892). Finally, we propose a correction factor for Koch's test statistic that better preserves the type I error...
  4. ncbi request reprint A retrospective analysis of the effect of noncompliance on time to first major adverse cardiac event in LIPS
    Emmanuel Lesaffre
    Biostatistical Centre, Katholieke Universiteit Leuven, Leuven, Belgium
    Clin Ther 25:2431-47. 2003
    ....
  5. ncbi request reprint On the variability of covariate adjustment. experience with Koch's method for evaluating the absolute difference in proportions in randomized clinical trials
    Emmanuel Lesaffre
    Biostatistical Centre, Catholic University of Leuven, U Z St Rafael, Kapucijnenvoer 35, 3000 Leuven, Belgium
    Control Clin Trials 23:127-42. 2002
    ..Analytic results will be given to quantify this risk and a simulation study illustrates our findings...
  6. doi request reprint Factors that influence data quality in caries experience detection: a multilevel modeling approach
    T Mutsvari
    L BioStat, Leuven, Belgium
    Caries Res 44:438-44. 2010
    ..In our analysis, we show that the dentition type and tooth or surface type affect the quality of caries experience detection...
  7. ncbi request reprint Assessment of caries experience in epidemiological surveys: a review
    J O Agbaje
    Department of Conservative Dentistry, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University of Leuven, Belgium
    Community Dent Health 29:14-9. 2012
    ..To review aspects of methods for assessing caries experience (CE) in epidemiological surveys...
  8. ncbi request reprint Modelling bivariate ordinal responses smoothly with examples from ophthalmology and genetics
    R Bustami
    Biostatistical Center, Katholieke Universiteit Leuven, Kapucijnenvoer 35, B-3000 Leuven, Belgium
    Stat Med 20:1825-42. 2001
    ..The second study is a twin study, where the association between the elements of twin pairs is of primary interest. The results show that smoothing on the association level can give a significant improvement to the model fit...
  9. ncbi request reprint Sensitivity analysis for nonrandom dropout: a local influence approach
    G Verbeke
    Biostatistical Centre, Katholieke Universiteit Leuven, Belgium
    Biometrics 57:7-14. 2001
    ..The influence of perturbing a missing-at-random dropout model in the direction of nonrandom dropout is explored. The method is applied to data from a randomized experiment on the inhibition of testosterone production in rats...
  10. ncbi request reprint Effect of caries experience in primary molars on cavity formation in the adjacent permanent first molar
    R Leroy
    School of Dentistry, Oral Pathology, Maxillofacial Surgery, Leuven, Belgium
    Caries Res 39:342-9. 2005
    ..No significant benefit from restoring primary molars could be demonstrated, possibly because of methodological limitations...
  11. doi request reprint Correcting for misclassification for a monotone disease process with an application in dental research
    M J García-Zattera
    L BioStat, Katholieke Universiteit Leuven, Leuven, Belgium
    Stat Med 29:3103-17. 2010
    ..Finally, the analyses of the motivating problem are presented...
  12. ncbi request reprint Measuring oral health behaviour in Flemish health care workers: an application of the theory of planned behaviour
    A Defranc
    Catholic University Leuven, Belgium
    Community Dent Health 25:107-14. 2008
    ..This study describes the development and validation of a questionnaire to measure the determinants of oral health related behaviour in health care workers, based on the Theory of Planned Behaviour (TPB)...
  13. pmc Tauroconjugation of cholic acid stimulates 7 alpha-dehydroxylation by fecal bacteria
    J Van Eldere
    Rega Institute for Medical Research and Biostatistical Centre, Department of Epidemiology, Catholic University of Leuven, Belgium
    Appl Environ Microbiol 62:656-61. 1996
    ..We conclude that the increased 7 alpha-dehydroxylation of tauroconjugated cholic acid depends on the reduction of taurine to H2S, which is a necessary growth factor for the 7 alpha-dehydroxylating bacteria...
  14. ncbi request reprint [In the interests of taking one's time even when one reads a scientific article! Critical review of the literature on tooth eruption]
    R Leroy
    Centre de Biostatistiques de la KULeuven Kapucijnenvoer 35 B 3000 Leuven
    Rev Belge Med Dent (1984) 56:245-57. 2001
    ..Different items are exemplified with articles that deal with the emergence of permanent teeth...
  15. ncbi request reprint The clinicopathological and prognostic relevance of cytokeratin 7 and 19 expression in hepatocellular carcinoma. A possible progenitor cell origin
    A Durnez
    Department of Morphology and Molecular Pathology, KULeuven University Hospital Gasthuisberg, Belgium
    Histopathology 49:138-51. 2006
    ..Therefore, our aim was to study the occurrence and clinicopathological characteristics of HCC expressing CK7 and/or CK19 in 109 Caucasian patients...
  16. doi request reprint An application of Harrell's C-index to PH frailty models
    R Van Oirbeek
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Katholieke Universiteit Leuven, Kapucijnenvoer 35, blok D, Bus 7001, B3000 Leuven, Belgium
    Stat Med 29:3160-71. 2010
    ..The 95 per cent confidence/credible intervals also possess good coverage properties, given that the point estimates perform good. The performance of the C-indices is evaluated on a real data set...
  17. ncbi request reprint An overview of group sequential methods in longitudinal clinical trials
    B Spiessens
    Biostatistical Center, Catholic University of Leuven, U Z St Rafael, Kapucijnenvoer 35, B 3000 Leuven, Belgium
    Stat Methods Med Res 9:497-515. 2000
    ..Furthermore, it tries to answer some practical questions that may arise during the conduct of interim analyses in longitudinal trials. Simulations have been carried out to obtain insight in these practical considerations...
  18. ncbi request reprint Low back pain in Flemish adolescents and the role of perceived social support and effect on the perception of back pain
    F Staes
    Faculty of Physical Education and Physiotherapy, Department of Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    Acta Paediatr 92:444-51. 2003
    ..To document the prevalence of low back pain (LBP) in Flemish adolescents and to recognize the association between perceived social support and affect and medical consultation and reduction of activities...
  19. ncbi request reprint Modelling tooth emergence data based on multivariate interval-censored data
    K Bogaerts
    Catholic University of Leuven, Biostatistical Centre, Leuven, Belgium
    Stat Med 21:3775-87. 2002
    ..Central to our paper is to provide appropriate statistical models to resolve some dental questions on emergence. The analyses are based on data from the longitudinal Signal-Tandmobiel study...
  20. doi request reprint Establishing the relationship between nurse staffing and hospital mortality using a clustered discrete-time logistic model
    L Diya
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Katholieke Universiteit Leuven, Kapucijnenvoer 35, blok D, Bus 7001, B3000 Leuven, and Universiteit Hasselt, Belgium
    Stat Med 29:778-85. 2010
    ..Lower nursing unit staffing levels in the general nursing units were associated with high in-hospital mortality in units past the traditional cardiac surgery nursing units...
  21. ncbi request reprint Smooth random effects distribution in a linear mixed model
    Wendimagegn Ghidey
    Biostatistical Centre, Catholic University of Leuven, Kapucynenvoer 35, B 3000 Leuven, Belgium
    Biometrics 60:945-53. 2004
    ..A simulation study shows that our approach yields almost unbiased estimates of the regression and the smoothing parameters in small sample settings. Consistency of the estimates is shown in a particular case...
  22. ncbi request reprint The zero-inflated negative binomial regression model with correction for misclassification: an example in caries research
    Samuel M Mwalili
    Statistics and Actuarial Sciences, Jorno Kenyatta University of Agriculture and Technology, Kenya
    Stat Methods Med Res 17:123-39. 2008
    ..Using our example, we illustrate how a non-differential misclassification process for each examiner can lead to differential misclassification overall...
  23. ncbi request reprint Power and sample size calculations for discrete bounded outcome scores
    Roula Tsonaka
    Biostatistical Centre, Catholic University of Leuven, Belgium
    Stat Med 25:4241-52. 2006
    ..A simulation study evaluates the performance of our method which is also applied to the ECASS-1 stroke study...
  24. ncbi request reprint A two-part joint model for the analysis of survival and longitudinal binary data with excess zeros
    Dimitris Rizopoulos
    Biostatistical Centre, Catholic University of Leuven, U Z St Rafael, Kapucijnenvoer 35, B 3000 Leuven, Belgium
    Biometrics 64:611-9. 2008
    ....
  25. ncbi request reprint Baseline and treatment effect heterogeneity for survival times between centers using a random effects accelerated failure time model with flexible error distribution
    Arnost Komarek
    Biostatistical Centre, Katholieke Universiteit Leuven, Kapucijnenvoer 35, 3000 Leuven, Belgium
    Stat Med 26:5457-72. 2007
    ..For computational convenience, the computations are based on Markov chain Monte Carlo techniques. The proposed method is illustrated on the disease-free survival times of early breast cancer patients collected in the EORTC trial 10854...
  26. doi request reprint Variability in permanent tooth emergence sequences in Flemish children
    Roos Leroy
    School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Leuven, Belgium
    Eur J Oral Sci 116:11-7. 2008
    ..These variations 'cover' 84-88% of all sequences. The presentation of emergence sequences solely based on means or medians should thus be regarded as misleading...
  27. doi request reprint Factors associated with prevalence and severity of caries experience in preschool children
    Dominique Declerck
    School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Leuven, Belgium
    Community Dent Oral Epidemiol 36:168-78. 2008
    ....
  28. doi request reprint Belgian observational drug utilization study of pimecrolimus cream 1% in routine daily practice in atopic dermatitis
    Marc De Backer
    Novartis Pharma, Vilvoorde, Belgium
    Dermatology 217:156-63. 2008
    ..For reimbursement purposes of pimecrolimus cream 1%, the Belgian authorities asked to document its consumption, its topical corticosteroid-sparing effect and quality of life within the routine clinical practice...
  29. ncbi request reprint Reported methodological quality of split-mouth studies
    Emmanuel Lesaffre
    Biostatistical Centre, Catholic University Leuven, Leuven, Belgium
    J Clin Periodontol 34:756-61. 2007
    ..The aim was to conduct a systematic review of the reported methodology of clinical studies using a split-mouth design published in dental journals over a 1-year period (2004)...
  30. ncbi request reprint The logistic transform for bounded outcome scores
    Emmanuel Lesaffre
    Biostatistical Centre, Catholic University of Leuven, U Z St Rafael, Kapucijnenvoer 35, B 3000 Leuven, Belgium
    Biostatistics 8:72-85. 2007
    ..A simulation study compares the performance of our approach with the two-sample Wilcoxon test and with OP regression. Finally, the different methods are illustrated on two data sets...
  31. ncbi request reprint A Bayesian analysis of multivariate doubly-interval-censored dental data
    Arnost Komarek
    Biostatistical Centre, Katholieke Universiteit Leuven, Kapucijnenvoer 35, B 3000 Leuven, Belgium
    Biostatistics 6:145-55. 2005
    ..To tackle the problem of the large number of left-censored observations a similar Finnish data set was introduced. Our analysis shows no convincing effect of fluoride-intake on caries development...
  32. ncbi request reprint Effect of fluvastatin on long-term outcome after coronary revascularization with stent implantation
    Francesco Saia
    Erasmus MC, Thoraxcenter, Rotterdam, The Netherlands
    Am J Cardiol 93:92-5. 2004
    ..4, p = 0.03)...
  33. ncbi request reprint Multivariate survival analysis for the identification of factors associated with cavity formation in permanent first molars
    Roos Leroy
    School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Leuven, Belgium
    Eur J Oral Sci 113:145-52. 2005
    ..The multiple survival analysis confirmed the major impact of the caries status of the deciduous dentition and self-reported oral hygiene habits on the incidence of cavities in permanent first molars...
  34. ncbi request reprint Factors influencing the survival of cryopreserved homografts. The second homograft performs as well as the first
    Bart Meyns
    Department of Cardiac Surgery, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
    Eur J Cardiothorac Surg 28:211-6; discussion 216. 2005
    ..To determine the life span of cryopreserved homografts implanted in the right ventricular outflow tract and the factors influencing it...
  35. ncbi request reprint Impact of caries experience in the deciduous molars on the emergence of the successors
    Roos Leroy
    Catholic University Leuven, School of Dentistry, Oral Pathology and Maxillofacial Surgery and Biostatistical Centre, Leuven, Belgium
    Eur J Oral Sci 111:106-10. 2003
    ..In conclusion, when considering permanent tooth emergence ages, caries experience in the primary dentition should be taken into account...
  36. ncbi request reprint A comparison of group sequential methods for binary longitudinal data
    Bart Spiessens
    Biostatistical Center, Catholic University of Leuven, U Z St Rafael, Kapucijnenvoer 35, B 3000 Leuven, Belgium
    Stat Med 22:501-15. 2003
    ..The comparison is illustrated with simulations using a randomized clinical trial for toenail fungal infection...
  37. ncbi request reprint An overview of methods for interval-censored data with an emphasis on applications in dentistry
    Emmanuel Lesaffre
    Katholieke Universiteit Leuven, Biostatistical Centre, Kapucijnenvoer 35, B 3000 Leuven, Belgium
    Stat Methods Med Res 14:539-52. 2005
    ..A flexible AFT model (avoiding parametric assumptions on the distribution of the error term) is described in greater detail and is used to solve a typical dental question in a longitudinal oral health study...
  38. ncbi request reprint The emergence of permanent teeth in Flemish children
    Roos Leroy
    School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University of Leuven, Belgium
    Community Dent Oral Epidemiol 31:30-9. 2003
    ..Most mandibular teeth emerged significantly before their antagonists, in boys as well as in girls. These findings are in agreement with other studies on the emergence of permanent teeth...
  39. ncbi request reprint Continuous retrograde blood cardioplegia is associated with lower hospital mortality after heart valve surgery
    Willem J Flameng
    Cardiac Surgery, Katholieke Universiteit Leuven, Belgium
    J Thorac Cardiovasc Surg 125:121-5. 2003
    ..We investigated possible factors, including cardioplegia techniques, influencing hospital mortality in patients undergoing cardiac valve surgery...
  40. ncbi request reprint Estimating disease prevalence in a Bayesian framework using probabilistic constraints
    Dirk Berkvens
    Department of Animal Health, Institute of Tropical Medicine, Antwerp, Belgium
    Epidemiology 17:145-53. 2006
    ..We illustrate our approach using data collected in a study on the prevalence of porcine cysticercosis with verification from external data...
  41. ncbi request reprint The effect of fluorides and caries in primary teeth on permanent tooth emergence
    Roos Leroy
    Catholic University Leuven, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Leuven, Belgium
    Community Dent Oral Epidemiol 31:463-70. 2003
    ..Caries experience in the primary molars had a more pronounced impact on the timing of emergence of the successors than exposure to any of the four fluoride parameters...
  42. ncbi request reprint Superiority, equivalence, and non-inferiority trials
    Emmanuel Lesaffre
    Biostatistical Centre, Catholic University of Leuven, Leuven, Belgium
    Bull NYU Hosp Jt Dis 66:150-4. 2008
    ..Special attention is paid to the practical implications when setting up a non-inferiority trial. Illustrations are taken from a clinical trial in osteoarthritis and from thrombolytic research...
  43. ncbi request reprint Group sequential methods for an ordinal logistic random-effects model under misspecification
    Bart Spiessens
    Biostatistical Center, Catholic University of Leuven, Belgium
    Biometrics 58:569-75. 2002
    ..Extensive simulations based on a toenail dermatophyte onychomycosis trial are used to illustrate our results...
  44. ncbi request reprint Mammography screening attendance: meta-analysis of the effect of direct-contact invitation
    Kris Denhaerynck
    University Center for Cancer Prevention, University Hospital Leuven, Leuven, Belgium
    Am J Prev Med 25:195-203. 2003
    ..Personal or telephone contact methods are often used to increase attendance for mammography screening. A meta-analysis of the literature was performed to assess the overall effect of direct-contact recruitment on mammography participation...
  45. ncbi request reprint Valved jugular vein segments for right ventricular outflow tract reconstruction in young sheep
    Paul Herijgers
    Department of Cardiac Surgery and Center for Experimental Surgery and Anesthesiology, Katholieke Universiteit Leuven, Minderbroedersstraat 17, 3000 Leuven, Belgium
    J Thorac Cardiovasc Surg 124:798-805. 2002
    ..This study was undertaken to investigate the degeneration and calcification of valved bovine jugular vein segments for right ventricular outflow tract reconstruction in juvenile sheep...
  46. ncbi request reprint Assessment of the relative advantage of various artesunate-based combination therapies by a multi-treatment Bayesian random-effects meta-analysis
    Frans Herwig Jansen
    Fondation ACT ion Afrique, Bruxelles, Belgium
    Am J Trop Med Hyg 77:1005-9. 2007
    ..Annual follow-up on the data published is intended to reveal the changes in the relative drug efficacy values of ACTs...
  47. ncbi request reprint Adverse outcomes in Belgian acute hospitals: retrospective analysis of the national hospital discharge dataset
    Koen Van den Heede
    Center for Health Services and Nursing Research, Catholic University Leuven, Leuven, Belgium
    Int J Qual Health Care 18:211-9. 2006
    ..The prevalence and variability of adverse outcome rates in Belgian acute hospitals is examined by using the national hospital discharge database...
  48. ncbi request reprint Stroke rehabilitation in Europe: what do physiotherapists and occupational therapists actually do?
    Liesbet De Wit
    Department of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Belgium
    Stroke 37:1483-9. 2006
    ..Little is known about their content. This study aimed to define and compare the content of PT and OT for stroke patients between 4 European rehabilitation centers...
  49. ncbi request reprint Latent-variable models for longitudinal data with bivariate ordinal outcomes
    David Todem
    Department of Epidemiology, Division of Biostatistics, Michigan State University, B601 West Fee Hall, East Lansing, MI 48823, USA
    Stat Med 26:1034-54. 2007
    ..Data from a psychiatric trial, the Fluvoxamine (an antidepressant drug) study, are used to illustrate the methodology...
  50. ncbi request reprint Effect of intervention through a pharmaceutical care program on patient adherence with prescribed once-daily atorvastatin
    Bernard Vrijens
    AARDEX Ltd, Rue des Cyclistes Frontière 24, Visé, Belgium
    Pharmacoepidemiol Drug Saf 15:115-21. 2006
    ..The objective of this study was to estimate the effect of a pharmaceutical care program on the adherence of once-daily atorvastatin treatment in patients with elevated cholesterol levels...
  51. ncbi request reprint Motor and functional recovery after stroke: a comparison of 4 European rehabilitation centers
    Liesbet De Wit
    Katholieke Universiteit Leuven, Faculty of Kinesiology and Rehabilitation Sciences, Tervuursevest 101, Heverlee, Belgium
    Stroke 38:2101-7. 2007
    ..Outcome after first stroke varies significantly across Europe. This study was designed to compare motor and functional recovery after stroke between four European rehabilitation centers...
  52. ncbi request reprint Bayes and diagnostic testing
    Emmanuel Lesaffre
    Biostatistical Centre, Catholic University of Leuven, Leuven, Belgium
    Vet Parasitol 148:58-61. 2007
    ..The influence of the prior information on the final result may not be ignored. Guidance for the choice of prior information not in conflict with the data can be obtained from a set of statistics and indices (DIC, p(D), Bayes-p)...
  53. ncbi request reprint Measuring the intensity of nursing care: making use of the Belgian Nursing Minimum Data Set
    Walter Sermeus
    Center for Health Services and Nursing Research, Catholic University Leuven, Belgium
    Int J Nurs Stud 45:1011-21. 2008
    ..It was developed for the measurement of nursing care in acute hospitals. It is used to support healthcare management & policy decision making such as hospital financing and nurse staffing decisions...
  54. ncbi request reprint Use of time by stroke patients: a comparison of four European rehabilitation centers
    Liesbet De Wit
    Department of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Belgium
    Stroke 36:1977-83. 2005
    ..The aim of the present study was to identify differences in the use of time by stroke patients in 4 rehabilitation centers in 4 European countries...
  55. ncbi request reprint A general method for dealing with misclassification in regression: the misclassification SIMEX
    Helmut Kuchenhoff
    Department of Statistics, Ludwig Maximilians Universitat Munchen, D 80799 Munchen, Germany
    Biometrics 62:85-96. 2006
    ..We apply our method to a study on caries with a misclassified longitudinal response...
  56. ncbi request reprint Use and misuse of the p-value
    Emmanuel Lesaffre
    Biostatistical Centre, Catholic University of Leuven, Leuven, Belgium
    Bull NYU Hosp Jt Dis 66:146-9. 2008
    ..It will also be shown that the (95%) confidence interval is to be preferred over the p-value as a statistical inference tool...