Research Topics

Genomes and Genes

Lode Godderis

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. request reprint
    Godderis L, Aka P, Mateuca R, Kirsch Volders M, Lison D, Veulemans H. Dose-dependent influence of genetic polymorphisms on DNA damage induced by styrene oxide, ethylene oxide and gamma-radiation. Toxicology. 2006;219:220-9 pubmed
    ..The influence of hOGG1326 on TL was borderline dose-dependent. We conclude that the influence of genetic polymorphisms of enzymes involved in DNA repair on induced genotoxicity depends on exposure dose. ..
  2. Godderis L, De Raedt K, Tabish A, Poels K, Maertens N, De Ruyck K, et al. Epigenetic changes in lymphocytes of solvent-exposed individuals. Epigenomics. 2012;4:269-77 pubmed publisher
    ..POPULATION & METHODS: A cross-sectional study was set up in 41 referents, 128 solvent workers and 23 CTE patients...
  3. Godderis L, Thomas R, Hubbard A, Tabish A, Hoet P, Zhang L, et al. Effect of chemical mutagens and carcinogens on gene expression profiles in human TK6 cells. PLoS ONE. 2012;7:e39205 pubmed publisher
    ..Our findings expand our understanding of the transcriptomic response to genotoxic carcinogens, revealing the alteration of diverse sets of genes and pathways involved in cellular homeostasis and cell cycle control. ..

Detail Information

Publications3

  1. request reprint
    Godderis L, Aka P, Mateuca R, Kirsch Volders M, Lison D, Veulemans H. Dose-dependent influence of genetic polymorphisms on DNA damage induced by styrene oxide, ethylene oxide and gamma-radiation. Toxicology. 2006;219:220-9 pubmed
    ..The influence of hOGG1326 on TL was borderline dose-dependent. We conclude that the influence of genetic polymorphisms of enzymes involved in DNA repair on induced genotoxicity depends on exposure dose. ..
  2. Godderis L, De Raedt K, Tabish A, Poels K, Maertens N, De Ruyck K, et al. Epigenetic changes in lymphocytes of solvent-exposed individuals. Epigenomics. 2012;4:269-77 pubmed publisher
    ..POPULATION & METHODS: A cross-sectional study was set up in 41 referents, 128 solvent workers and 23 CTE patients...
  3. Godderis L, Thomas R, Hubbard A, Tabish A, Hoet P, Zhang L, et al. Effect of chemical mutagens and carcinogens on gene expression profiles in human TK6 cells. PLoS ONE. 2012;7:e39205 pubmed publisher
    ..Our findings expand our understanding of the transcriptomic response to genotoxic carcinogens, revealing the alteration of diverse sets of genes and pathways involved in cellular homeostasis and cell cycle control. ..