Research Topics
| Piet DirixSummaryAffiliation: Katholieke Universiteit Leuven Country: Belgium Publications
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Detail Information
Publications
Efficacy of the BioXtra dry mouth care system in the treatment of radiotherapy-induced xerostomiaPiet Dirix
Department of Radiation Oncology, Leuvens Kanker Instituut, University Hospital Gasthuisberg, Herestraat 49, 3000, Leuven, Belgium
Support Care Cancer 15:1429-36. 2007..Symptomatic treatment consists of stringent oral hygiene to prevent oral infections and saliva substitutes to increase comfort. The aim of the study was to evaluate the clinical effectiveness of the BioXtra (BX) dry mouth care system...
The influence of xerostomia after radiotherapy on quality of life: results of a questionnaire in head and neck cancerPiet Dirix
Department of Radiation Oncology, Leuvens Kanker Instituut LKI, University Hospital Gasthuisberg, Herestraat 49, Leuven, Belgium
Support Care Cancer 16:171-9. 2008..The aim of the study was to evaluate the degree of xerostomia in survivors of head and neck cancer and to determine its impact on quality of life...
Malignancies of the nasal cavity and paranasal sinuses: long-term outcome with conventional or three-dimensional conformal radiotherapyPiet Dirix
Department of Radiation Oncology, Leuvens Kanker Instituut, University Hospital Gasthuisberg, Leuven, Belgium
Int J Radiat Oncol Biol Phys 69:1042-50. 2007..To evaluate the long-term clinical outcome and toxicity of conventional and three-dimensional conformal radiotherapy for malignancies of the nasal cavity and paranasal sinuses...
Diffusion-weighted magnetic resonance imaging early after chemoradiotherapy to monitor treatment response in head-and-neck squamous cell carcinomaVincent Vandecaveye
Department of Radiology, University Hospitals Leuven, Leuven, Belgium
Int J Radiat Oncol Biol Phys 82:1098-107. 2012..To evaluate diffusion-weighted imaging (DWI) for assessment of treatment response in head and neck squamous cell carcinoma (HNSCC) three weeks after the end of chemoradiotherapy (CRT)...
Value of intensity-modulated radiotherapy in Stage IV head-and-neck squamous cell carcinomaPiet Dirix
Department of Radiation Oncology, Leuvens Kankerinstituut, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium
Int J Radiat Oncol Biol Phys 78:1373-80. 2010..To review outcome and toxicity of Stage IVa and IVb head-and-neck squamous cell carcinoma patients treated with concomitant chemotherapy and intensity-modulated radiotherapy (IMRT) according to a hybrid fractionation schedule...
Diffusion-weighted MRI for nodal staging of head and neck squamous cell carcinoma: impact on radiotherapy planningPiet Dirix
Department of Radiation Oncology, Leuvens Kankerinstituut LKI, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium
Int J Radiat Oncol Biol Phys 76:761-6. 2010..To evaluate the use of diffusion-weighted magnetic resonance imaging (DW-MRI) for nodal staging and its impact on radiotherapy (RT) planning...
Impact of adding concomitant chemotherapy to hyperfractionated accelerated radiotherapy for advanced head-and-neck squamous cell carcinomaSandra Nuyts
Department of Radiation Oncology, Leuvens Kankerinstituut, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium
Int J Radiat Oncol Biol Phys 73:1088-95. 2009..To evaluate the feasibility and efficacy of a hyperfractionated accelerated radiotherapy (RT) schedule combined with concomitant chemotherapy (Cx) in patients with locally advanced head-and-neck squamous cell carcinoma...
Intensity-modulated radiotherapy for sinonasal cancer: improved outcome compared to conventional radiotherapyPiet Dirix
Department of Radiation Oncology, Leuvens Kankerinstituut LKI, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium
Int J Radiat Oncol Biol Phys 78:998-1004. 2010..To evaluate clinical outcome and toxicity of postoperative intensity-modulated radiotherapy (IMRT) for malignancies of the nasal cavity and paranasal sinuses...
Early experience with a hybrid accelerated radiotherapy schedule for locally advanced head and neck cancerSandra Nuyts
Department of Radiation Oncology, Leuvens Kanker Instituut LKI, University Hospital Gasthuisberg, Leuven, Belgium
Head Neck 29:720-30. 2007..Our aim was to determine feasibility and efficacy of a hybrid radiotherapy schedule in locally advanced head and neck cancer...
Diffusion-weighted magnetic resonance imaging to evaluate major salivary gland function before and after radiotherapyPiet Dirix
Department of Radiation Oncology, Leuvens Kankerinstituut LKI, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, Leuven, Belgium
Int J Radiat Oncol Biol Phys 71:1365-71. 2008..To evaluate diffusion-weighted (DW)-MRI as a noninvasive tool to investigate major salivary gland function before and after radiotherapy (RT) for head and neck cancer (HNC)...
Outcome after re-irradiation of head and neck cancer patientsNele Platteaux
Department of Radiation Oncology, Leuvens Kankerinstituut, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium
Strahlenther Onkol 187:23-31. 2011..To retrospectively report the outcome of head and neck cancer patients following re-irradiation...
Role and value of diffusion-weighted MRI in the radiotherapeutic management of head and neck cancerMaarten Lambrecht
Department of Radiation Oncology, LKI, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, Leuven 3000, Belgium
Expert Rev Anticancer Ther 10:1451-9. 2010..In this article, we aim to bundle the current experience on DW-MRI in HNSCC and elaborate on its potential value and drawbacks at different time points before, during and after radiotherapy...
Dose painting in radiotherapy for head and neck squamous cell carcinoma: value of repeated functional imaging with (18)F-FDG PET, (18)F-fluoromisonidazole PET, diffusion-weighted MRI, and dynamic contrast-enhanced MRIPiet Dirix
Department of Radiation Oncology, Leuvens Kankerinstituut, University Hospitals Leuven, Leuven, Belgium
J Nucl Med 50:1020-7. 2009....
Post-operative intensity-modulated radiotherapy for malignancies of the nasal cavity and paranasal sinusesPiet Dirix
Department of Radiation Oncology, Leuvens Kankerinstituut, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, Leuven, Belgium
Radiother Oncol 85:385-91. 2007..To evaluate the clinical outcome and toxicity of post-operative intensity-modulated radiotherapy (IMRT) for malignancies of the nasal cavity and paranasal sinuses...
Head and neck squamous cell carcinoma: value of diffusion-weighted MR imaging for nodal stagingVincent Vandecaveye
Department of Radiology, University Hospitals Leuven, Leuven, Belgium
Radiology 251:134-46. 2009..To evaluate diffusion-weighted (DW) magnetic resonance (MR) imaging, as compared with turbo spin-echo MR imaging, for the detection of nodal metastases in head and neck squamous cell carcinoma (HNSCC)...
Predictive value of diffusion-weighted magnetic resonance imaging during chemoradiotherapy for head and neck squamous cell carcinomaVincent Vandecaveye
Department of Radiology, University Hospitals Leuven, Leuven, Belgium
Eur Radiol 20:1703-14. 2010..To evaluate diffusion-weighted (DWI) magnetic resonance imaging (MRI) for treatment prediction during chemoradiotherapy (CRT) of head and neck squamous cell carcinoma (HNC)...
Evidence-based organ-sparing radiotherapy in head and neck cancerPiet Dirix
Department of Radiation Oncology, Leuven Cancer Institute LKI, Leuven, Belgium
Lancet Oncol 11:85-91. 2010..Because xerostomia and dysphagia are the main causes of decreased quality of life after radiotherapy for head and neck cancer, the prevention of these two complications will form the focus of this review...
Incidence of isolated regional recurrence after definitive (chemo-) radiotherapy for head and neck squamous cell carcinomaMaarten Lambrecht
Department of Radiation Oncology, University Hospitals Leuven, Herestraat, Leuven, Belgium
Radiother Oncol 93:498-502. 2009..To evaluate the incidence and localization of regional recurrences after definitive (chemo-) radiotherapy for head and neck squamous cell carcinoma (HNSCC)...
Prognostic influence of retropharyngeal lymph node metastasis in squamous cell carcinoma of the oropharynxPiet Dirix
Department of Radiation Oncology, Leuvens Kanker Instituut (LKI, University Hospital Gasthuisberg, Leuven, Belgium
Int J Radiat Oncol Biol Phys 65:739-44. 2006..Patients are particularly at risk for regional recurrence, resulting in worse disease-specific survival. Retropharyngeal node involvement should be taken into account in designing the treatment plan for these patients...
Dysphagia in head and neck cancer patients treated with chemoradiotherapyNele Platteaux
Department of Radiation Oncology, Leuven Cancer Institute, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, Leuven, Belgium
Dysphagia 25:139-52. 2010..However, more research is needed to further decrease the incidence of dysphagia and improve quality of life...
Detection of head and neck squamous cell carcinoma with diffusion weighted MRI after (chemo)radiotherapy: correlation between radiologic and histopathologic findingsVincent Vandecaveye
Department of Radiology, University Hospitals Leuven, Leuven, Belgium
Int J Radiat Oncol Biol Phys 67:960-71. 2007..To investigate the value of diffusion weighted magnetic resonance imaging (DW-MRI) in differentiating persistent or recurrent head and neck squamous cell carcinoma (HNSCC) from nontumoral postradiotherapeutic alterations...
Radiation-induced xerostomia in patients with head and neck cancer: a literature reviewPiet Dirix
Department of Radiation Oncology, Leuven Cancer Institute, University Hospital Gasthuisberg, Leuven, Belgium
Cancer 107:2525-34. 2006....
Brachial plexopathy after chemoradiotherapy for head and neck squamous cell carcinomaNele Platteaux
Department of Radiation Oncology, Leuvens Kankerinstituut, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium
Strahlenther Onkol 186:517-20. 2010..To evaluate late brachial plexopathy after primary chemoradiotherapy for locally advanced head and neck squamous cell carcinoma...
Applications of diffusion-weighted magnetic resonance imaging in head and neck squamous cell carcinomaVincent Vandecaveye
Department of Radiology, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Neuroradiology 52:773-84. 2010..The possible consequences of adding DWI towards therapeutic management are outlined...
Dysphagia after chemoradiotherapy for head-and-neck squamous cell carcinoma: dose-effect relationships for the swallowing structuresPiet Dirix
Department of Radiation Oncology, Leuvens Kankerinstituut, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium
Int J Radiat Oncol Biol Phys 75:385-92. 2009..To evaluate late dysphagia after chemoradiotherapy for locally advanced head-and-neck squamous cell carcinoma, and to examine its correlation with clinical and dosimetric parameters...
Radiotherapy for laryngeal squamous cell carcinoma: current standardsPiet Dirix
Department of Radiation Oncology, Leuvens Kankerinstituut LKI, University Hospitals Leuven, Campus Gasthuisberg, Herestraat 49, B 3000 Leuven, Belgium
Expert Rev Anticancer Ther 10:1461-9. 2010..This article will attempt to put the various approaches into perspective...
Retropharyngeal nodes in squamous cell carcinoma of oropharynx: incidence, localization, and implications for target volumeBarbara Bussels
Department of Radiation Oncology, Leuvens Kanker Instituut (LKI, University Hospital Gasthuisberg, Leuven, Belgium
Int J Radiat Oncol Biol Phys 65:733-8. 2006..In node-negative necks, inclusion of RP nodes into the target volume is advised in posterior pharyngeal wall tumors...
The role of whole pelvic radiotherapy in locally advanced prostate cancerPiet Dirix
Department of Radiation Oncology, University Hospital Gasthuisberg, Leuven, Belgium
Radiother Oncol 79:1-14. 2006..Although, the absolute incidence of positive nodes in locally advanced prostate cancer warrants elective radiotherapy, it is relatively low and the modest improvements to be expected may be undetected in the results of a small trial...
