Research Topics
| Geert R D'HaensSummaryAffiliation: Katholieke Universiteit Leuven Country: Belgium Publications
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Detail Information
Publications
Endoscopic and histological healing with infliximab anti-tumor necrosis factor antibodies in Crohn's disease: A European multicenter trialG D'Haens
Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
Gastroenterology 116:1029-34. 1999..Tumor necrosis factor (TNF) is a pivotal cytokine in intestinal inflammation. Controlled trials using a chimeric anti-TNF antibody (infliximab) have shown its efficacy in refractory Crohn's disease...
Infliximab (Remicade), a new biological treatment for Crohn's diseaseG R D'Haens
Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
Ital J Gastroenterol Hepatol 31:519-20. 1999..In conclusion, infliximab appears to offer a promising novel therapeutic agent for refractory and fistulizing Crohn's disease. Long-term risks and benefits remain to be determined...
Intravenous cyclosporine versus intravenous corticosteroids as single therapy for severe attacks of ulcerative colitisG D'Haens
Department of Internal Medicine, University Hospital Gasthuisberg, Leuven, Belgium
Gastroenterology 120:1323-9. 2001..We investigated the effects of intravenous (IV) cyclosporine as single IV therapy (without glucocorticosteroids) for severe UC and compared these with the response to glucocorticosteroids...
Anti-TNF therapy for Crohn's diseaseGeert D'Haens
Department of Gastroenterology at the University Hospital Gasthuisberg, Leuven, Belgium
Curr Pharm Des 9:289-94. 2003..Expected and unexpected safety toxicity data should caution clinicians to a certain extent against too liberal use of these agents interfering with very basic physiological events...
Infliximab as disease-modifying therapyGeert R D'Haens
Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
Eur J Gastroenterol Hepatol 15:233-7. 2003..Appropriate indications for using infliximab and growing experience with safety aspects have made this treatment a highly valuable tool in the management of Crohn's disease...
Therapy of metronidazole with azathioprine to prevent postoperative recurrence of Crohn's disease: a controlled randomized trialGeert R D'Haens
Department of Gastroenterology, Leuven University Hospitals, Leuven, Belgium
Gastroenterology 135:1123-9. 2008..Goal: We sought to examine whether metronidazole for 3 months together with azathioprine (AZA) for 12 months is superior to metronidazole alone to reduce recurrence of postoperative CD in "high-risk" patients...
