Marc De Hert

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. ncbi request reprint Remission criteria for schizophrenia: evaluation in a large naturalistic cohort
    Marc De Hert
    University Psychiatric Centre Catholic University Louvain, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Schizophr Res 92:68-73. 2007
  2. ncbi request reprint Reversibility of antipsychotic treatment-related diabetes in patients with schizophrenia: a case series of switching to aripiprazole
    Marc De Hert
    Diabetes Care 29:2329-30. 2006
  3. ncbi request reprint Screening for diabetes and other metabolic abnormalities in patients with schizophrenia and schizoaffective disorder: evaluation of incidence and screening methods
    Ruud van Winkel
    University Psychiatric Center, Katholieke Universiteit Leuven, Kortenberg, Belgium
    J Clin Psychiatry 67:1493-500. 2006
  4. doi request reprint The METEOR study of diabetes and other metabolic disorders in patients with schizophrenia treated with antipsychotic drugs. I. Methodology
    Marc De Hert
    UPC KUL Campus Kortenberg, Kortenberg, Belgium
    Int J Methods Psychiatr Res 19:195-210. 2010
  5. ncbi request reprint Second-generation and newly approved antipsychotics, serum prolactin levels and sexual dysfunctions: a critical literature review
    Marc De Hert
    UPC KU Leuven, Department of Neurosciences KU Leuven, Kortenberg, Belgium
    Expert Opin Drug Saf 13:605-24. 2014
  6. pmc Is the prevalence of metabolic syndrome and metabolic abnormalities increased in early schizophrenia? A comparative meta-analysis of first episode, untreated and treated patients
    Alex J Mitchell
    Leicestershire Partnership Trust, Leicester, UK
    Schizophr Bull 39:295-305. 2013
  7. doi request reprint Evaluation of the association between insight and symptoms in a large sample of patients with schizophrenia
    M A F De Hert
    University Psychiatric Centre, Catholic University Leuven campus Kortenberg, Leuvense Steenweg 517, Kortenberg, Belgium
    Eur Psychiatry 24:507-12. 2009
  8. doi request reprint Cardiovascular disease and diabetes in people with severe mental illness position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC
    M De Hert
    University Psychiatric, Centre Catholic University, Leuven campus Kortenberg, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Eur Psychiatry 24:412-24. 2009
  9. ncbi request reprint Anticholinergic use in hospitalised schizophrenic patients in Belgium
    Marc De Hert
    University Psychiatric Centre Katholieke Universiteit Leuven, campus Kortenberg, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Psychiatry Res 152:165-72. 2007
  10. doi request reprint Guidelines for screening and monitoring of cardiometabolic risk in schizophrenia: systematic evaluation
    M De Hert
    University Psychiatric Centre, KU Leuven, campus Kortenberg Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Br J Psychiatry 199:99-105. 2011

Collaborators

Detail Information

Publications78

  1. ncbi request reprint Remission criteria for schizophrenia: evaluation in a large naturalistic cohort
    Marc De Hert
    University Psychiatric Centre Catholic University Louvain, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Schizophr Res 92:68-73. 2007
    ..Little is known, however, about the added value of the time criterion in addition to the cross-sectional severity criterion...
  2. ncbi request reprint Reversibility of antipsychotic treatment-related diabetes in patients with schizophrenia: a case series of switching to aripiprazole
    Marc De Hert
    Diabetes Care 29:2329-30. 2006
  3. ncbi request reprint Screening for diabetes and other metabolic abnormalities in patients with schizophrenia and schizoaffective disorder: evaluation of incidence and screening methods
    Ruud van Winkel
    University Psychiatric Center, Katholieke Universiteit Leuven, Kortenberg, Belgium
    J Clin Psychiatry 67:1493-500. 2006
    ..To assess the diagnostic properties of 2 different screening guidelines for the detection of diabetes in patients diagnosed with schizophrenia...
  4. doi request reprint The METEOR study of diabetes and other metabolic disorders in patients with schizophrenia treated with antipsychotic drugs. I. Methodology
    Marc De Hert
    UPC KUL Campus Kortenberg, Kortenberg, Belgium
    Int J Methods Psychiatr Res 19:195-210. 2010
    ..The proportion of subjects presenting the pathologies of interest was relatively high, ranging from 28% for glycaemic disorders to 70% for lipid disorders...
  5. ncbi request reprint Second-generation and newly approved antipsychotics, serum prolactin levels and sexual dysfunctions: a critical literature review
    Marc De Hert
    UPC KU Leuven, Department of Neurosciences KU Leuven, Kortenberg, Belgium
    Expert Opin Drug Saf 13:605-24. 2014
    ..Using antipsychotic (AP) medication can increase prolactin (PRL) levels and place the patient at risk of sexual dysfunction (SD)...
  6. pmc Is the prevalence of metabolic syndrome and metabolic abnormalities increased in early schizophrenia? A comparative meta-analysis of first episode, untreated and treated patients
    Alex J Mitchell
    Leicestershire Partnership Trust, Leicester, UK
    Schizophr Bull 39:295-305. 2013
    ..We aimed to discover whether metabolic complications of schizophrenia (SZ) are present in first episode (FE) and unmedicated (UM) patients, in comparison with patients established on antipsychotic medication (AP)...
  7. doi request reprint Evaluation of the association between insight and symptoms in a large sample of patients with schizophrenia
    M A F De Hert
    University Psychiatric Centre, Catholic University Leuven campus Kortenberg, Leuvense Steenweg 517, Kortenberg, Belgium
    Eur Psychiatry 24:507-12. 2009
    ..The objective of the present study was to examine the association of insight into the illness with demographic variables and symptomatology in a sample of 1213 patients with schizophrenia...
  8. doi request reprint Cardiovascular disease and diabetes in people with severe mental illness position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC
    M De Hert
    University Psychiatric, Centre Catholic University, Leuven campus Kortenberg, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Eur Psychiatry 24:412-24. 2009
    ....
  9. ncbi request reprint Anticholinergic use in hospitalised schizophrenic patients in Belgium
    Marc De Hert
    University Psychiatric Centre Katholieke Universiteit Leuven, campus Kortenberg, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Psychiatry Res 152:165-72. 2007
    ..However, there were no significant differences in the prevalence of EPS with the exception of akathisia between FGA and SGA. Thus, through the use of anticholinergics, EPS induced by FGA can be effectively reduced...
  10. doi request reprint Guidelines for screening and monitoring of cardiometabolic risk in schizophrenia: systematic evaluation
    M De Hert
    University Psychiatric Centre, KU Leuven, campus Kortenberg Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Br J Psychiatry 199:99-105. 2011
    ..Metabolic and cardiovascular health problems have become a major focus for clinical care and research in schizophrenia...
  11. doi request reprint Second-generation antipsychotics and constipation: a review of the literature
    M De Hert
    University Psychiatric Centre, campus Kortenberg, Catholic University Louvain, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Eur Psychiatry 26:34-44. 2011
    ..Active screening, monitoring and treatment are recommended. Further research on incidence, prevalence, underlying mechanisms and preventive measures is required...
  12. pmc A case series: evaluation of the metabolic safety of aripiprazole
    Marc De Hert
    University Psychiatric Center Katholieke Universiteit Leuven, Leuvense Steenweg 517, 3070 Kortenberg, Belgium
    Schizophr Bull 33:823-30. 2007
    ..The MetS was reversed in 50% of patients at 3 months follow-up. Our results support the reversibility of recent onset diabetes on antipsychotic medication when detected early and followed by a switch to aripiprazole...
  13. ncbi request reprint Treatment with rosuvastatin for severe dyslipidemia in patients with schizophrenia and schizoaffective disorder
    Marc De Hert
    University Psychiatric Center, Katholieke Universiteit Leuven, Kortenberg, Belgium
    J Clin Psychiatry 67:1889-96. 2006
    ..Use of lipid-lowering drugs such as statins is recommended when lifestyle changes are not sufficient to reach the LDL goal. The efficacy and safety of rosuvastatin treatment were evaluated in schizophrenic patients...
  14. doi request reprint Do antipsychotic medications reduce or increase mortality in schizophrenia? A critical appraisal of the FIN-11 study
    Marc De Hert
    University Psychiatric Center, Catholic University Leuven, campus Kortenberg, Belgium
    Schizophr Res 117:68-74. 2010
    ....
  15. doi request reprint Physical health management in psychiatric settings
    M De Hert
    University Psychiatric Center, Katholieke Universiteit Leuven, campus Kortenberg, Leuvensesteenweg 517, B 3070 Kortenberg, Belgium
    Eur Psychiatry 25:S22-8. 2010
    ..This paper describes the practical aspects of this monitoring protocol and the results obtained 4 years after its implementation...
  16. pmc Prevalence and severity of antipsychotic related constipation in patients with schizophrenia: a retrospective descriptive study
    Marc De Hert
    University Psychiatric Centre Catholic University Louvain, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    BMC Gastroenterol 11:17. 2011
    ..They also have a number of side-effects. Constipation is thought to be common, and a potential serious side-effect, which has received little attention in recent literature...
  17. doi request reprint Prevalence and correlates of seclusion and restraint use in children and adolescents: a systematic review
    Marc De Hert
    University Psychiatric Centre, KUL Campus Kortenberg, Leuvensesteenweg 517, Kortenberg, Belgium
    Eur Child Adolesc Psychiatry 20:221-30. 2011
    ..In addition, there is a clear need for transparent policies and guidelines...
  18. ncbi request reprint Oral glucose tolerance tests in treated patients with schizophrenia. Data to support an adaptation of the proposed guidelines for monitoring of patients on second generation antipsychotics?
    Marc De Hert
    University Centre Sint Jozef, Katholieke Universiteit Leuven, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Eur Psychiatry 21:224-6. 2006
    ..A recent consensus conference has proposed guidelines for the monitoring for diabetes in patients with schizophrenia and also identifies the need of long-term prospective studies...
  19. ncbi request reprint Prevalence of the metabolic syndrome in patients with schizophrenia treated with antipsychotic medication
    Marc A De Hert
    University Center St Jozef, Catholic University Louvain, Leuvense Steenweg 517, 3070 Kortenberg, Belgium
    Schizophr Res 83:87-93. 2006
    ..The presence of the metabolic syndrome is an important risk factor for cardiovascular disease and diabetes. There are limited data on the prevalence of the metabolic syndrome in European patients suffering from schizophrenia...
  20. doi request reprint Metabolic parameters in the short- and long-term treatment of schizophrenia with sertindole or risperidone
    Marc De Hert
    University Psychiatric Center Catholic University Leuven, UPC KUL Campus Kortenberg, Leuvensesteenweg 517, Kortenberg, Belgium
    Eur Arch Psychiatry Clin Neurosci 261:231-9. 2011
    ..Treatment with either sertindole or risperidone did not appear to be associated with an increased comparative risk of developing metabolic syndrome. In general, the metabolic effects of sertindole and risperidone were similar...
  21. doi request reprint Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: A systematic review of randomized, placebo controlled trials and guidelines for clinical practice
    M De Hert
    Centre Catholic University Leuven, campus Kortenberg, Leuvensesteenweg 517, Kortenberg, Belgium
    Eur Psychiatry 26:144-58. 2011
    ..A good collaboration between child- and adolescent psychiatrists, general practitioners and paediatricians is essential to maximize overall outcomes and to reduce the likelihood of premature cardiovascular morbidity and mortality...
  22. doi request reprint Effects of cannabis use on age at onset in schizophrenia and bipolar disorder
    Marc De Hert
    University Psychiatric Centre Catholic University Leuven campus Kortenberg, Leuvense Steenweg 517, 3070 Kortenberg, Belgium
    Schizophr Res 126:270-6. 2011
    ..Cannabis use may decrease age at onset in both schizophrenia and bipolar disorder, given the evidence for substantial phenotypic and genetic overlap between both disorders...
  23. doi request reprint Knowledge about HIV in people with schizophrenia: a general population comparison
    Marc De Hert
    University Psychiatric Center Katholieke Universiteit Leuven, campus Kortenberg, Belgium
    Clin Schizophr Relat Psychoses 5:80-6. 2011
    ..Only a limited number of studies have evaluated the knowledge about HIV in people with schizophrenia...
  24. doi request reprint Typical and atypical antipsychotics differentially affect long-term incidence rates of the metabolic syndrome in first-episode patients with schizophrenia: a retrospective chart review
    Marc De Hert
    University Psychiatric Center Katholieke Universiteit Leuven, Leuvense Steenweg 517, 3070 Kortenberg, Belgium
    Schizophr Res 101:295-303. 2008
    ..There are limited data on the prevalence of MetS in patients with schizophrenia at the onset of the disorder and specifically no data on patients treated in the era when only first-generation antipsychotics were available...
  25. ncbi request reprint Major changes in glucose metabolism, including new-onset diabetes, within 3 months after initiation of or switch to atypical antipsychotic medication in patients with schizophrenia and schizoaffective disorder
    Ruud van Winkel
    University Psychiatric Center, Katholieke Universiteit Leuven, Kortenberg, Belgium
    J Clin Psychiatry 69:472-9. 2008
    ..To investigate 3-month changes in glucose metabolism in a naturalistic sample of patients with schizophrenia newly started on or switched to specific atypical antipsychotic medication therapy...
  26. doi request reprint Relationships between physical fitness, physical activity, smoking and metabolic and mental health parameters in people with schizophrenia
    Davy Vancampfort
    University Psychiatric Centre Catholic University Leuven, campus Kortenberg, Kortenberg, Belgium
    Psychiatry Res 207:25-32. 2013
    ..Less physically active patients who smoke and suffer from high levels of negative, depressive and/or cognitive symptoms might benefit from specific rehabilitation interventions aimed at increasing physical fitness...
  27. doi request reprint Prevalence of diabetes and the metabolic syndrome in a sample of patients with bipolar disorder
    Ruud van Winkel
    University Psychiatric Center Katholieke Universiteit Leuven, Kortenberg, Belgium
    Bipolar Disord 10:342-8. 2008
    ..There are limited data on the prevalence of the metabolic abnormalities in disorders other than schizophrenia in which antipsychotic medication is part of routine treatment...
  28. doi request reprint Lack of physical activity during leisure time contributes to an impaired health related quality of life in patients with schizophrenia
    Davy Vancampfort
    University Psychiatric Centre Catholic University Leuven, campus Kortenberg, Kortenberg, Belgium
    Schizophr Res 129:122-7. 2011
    ..We also evaluated whether the presence of metabolic syndrome (MetS) could explain the variability in HRQL in patients...
  29. doi request reprint Diabetes, physical activity participation and exercise capacity in patients with schizophrenia
    Davy Vancampfort
    campus Kortenberg, UPC KU Leuven, Kortenberg Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium
    Psychiatry Clin Neurosci 67:451-6. 2013
    ....
  30. ncbi request reprint Psychiatric diagnosis as an independent risk factor for metabolic disturbances: results from a comprehensive, naturalistic screening program
    Ruud van Winkel
    University Psychiatric Center Catholic University Leuven, Kortenberg, Belgium
    J Clin Psychiatry 69:1319-27. 2008
    ..Unconfounded differences in inherent vulnerability to metabolic disturbance may be hypothesized for different diagnostic groups with severe mental illness...
  31. doi request reprint A systematic review on physical therapy interventions for patients with binge eating disorder
    Davy Vancampfort
    University Psychiatric Centre, Catholic University of Leuven, campus Kortenberg, Kortenberg, Belgium
    Disabil Rehabil 35:2191-6. 2013
    ..The aim of this study was to systematically review randomised controlled trials (RCTs) evaluating physical therapy on binge eating and physical and mental health in BED patients...
  32. doi request reprint A review of physical activity correlates in patients with bipolar disorder
    Davy Vancampfort
    University Psychiatric Center, Catholic University Leuven, campus Kortenberg, Kortenberg, Belgium
    J Affect Disord 145:285-91. 2013
    ..The present review evaluates systematically quantitative studies of correlates of physical activity in patients with bipolar disorder...
  33. doi request reprint Body weight and metabolic adverse effects of asenapine, iloperidone, lurasidone and paliperidone in the treatment of schizophrenia and bipolar disorder: a systematic review and exploratory meta-analysis
    Marc De Hert
    University Psychiatric Centre, Catholic University Leuven, Kortenberg, Belgium
    CNS Drugs 26:733-59. 2012
    ..However, until now, the metabolic risk profile of the newly approved SGAs - asenapine, iloperidone, lurasidone and paliperidone (paliperidone extended release and paliperidone palmitate) - has not been compared...
  34. doi request reprint Differential effects of olanzapine and risperidone on plasma adiponectin levels over time: results from a 3-month prospective open-label study
    Martien Wampers
    University Psychiatric Centre Catholic University Leuven, campus Kortenberg, Kortenberg, Belgium
    Eur Neuropsychopharmacol 22:17-26. 2012
    ..The observed olanzapine-associated reduction in plasma adiponectin levels may at least partially contribute to the increased metabolic risk of olanzapine compared to risperidone...
  35. ncbi request reprint Body weight and self-esteem in patients with schizophrenia evaluated with B-WISE
    Marc De Hert
    University Psychiatric Center Katholieke Universiteit Leuven, Leuvense Steenweg 517, 3070 Kortenberg, Belgium
    Schizophr Res 88:222-6. 2006
    ..The second objective was to explore the association of B-WISE scores with the metabolic syndrome and glucose abnormalities...
  36. doi request reprint State anxiety, psychological stress and positive well-being responses to yoga and aerobic exercise in people with schizophrenia: a pilot study
    Davy Vancampfort
    Faculty of Kinesiology and Rehabilitation Sciences, Catholic University Leuven, Leuven, Belgium
    Disabil Rehabil 33:684-9. 2011
    ....
  37. doi request reprint Metabolic syndrome and metabolic abnormalities in bipolar disorder: a meta-analysis of prevalence rates and moderators
    Davy Vancampfort
    University Psychiatric Centre KU Leuven, campus Kortenberg, Kortenberg, Belgium
    Am J Psychiatry 170:265-74. 2013
    ..The authors sought to clarify the prevalence and moderators of metabolic syndrome in bipolar patients, accounting for subgroup differences...
  38. ncbi request reprint Associations between physical activity and the built environment in patients with schizophrenia: a multi-centre study
    Davy Vancampfort
    University Psychiatric Centre KU Leuven, campus Kortenberg, Department of Neurosciences KU Leuven, Belgium Department of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, Belgium Electronic address
    Gen Hosp Psychiatry 35:653-8. 2013
    ..This study investigated the variance in walking, moderate and vigorous physical activity (PA), explained by neighbourhood design and other environmental variables above and beyond the variance accounted for by demographical variables...
  39. doi request reprint Neurocognition in clinical high risk young adults who did or did not convert to a first schizophrenic psychosis: a meta-analysis
    Amber De Herdt
    Department of Rehabilitation Science, KU Leuven, Belgium
    Schizophr Res 149:48-55. 2013
    ..Therefore, the aim of the present meta-analysis was to compare the baseline NC performance between CHR-C and CHR-NC...
  40. doi request reprint Progressive muscle relaxation in persons with schizophrenia: a systematic review of randomized controlled trials
    Davy Vancampfort
    University Psychiatric Centre Catholic University Leuven, campus Kortenberg, Kortenberg, Belgium
    Clin Rehabil 27:291-8. 2013
    ..The aim of this systematic review was to assess the effectiveness of progressive muscle relaxation on psychological distress and anxiety symptoms and on response/remission for people with schizophrenia...
  41. doi request reprint Quality assessment of physical activity recommendations within clinical practice guidelines for the prevention and treatment of cardio-metabolic risk factors in people with schizophrenia
    Davy Vancampfort
    University Psychiatric Centre Catholic University Leuven, campus Kortenberg, Leuvensesteenweg 517, Kortenberg, Belgium
    Community Ment Health J 47:703-10. 2011
    ..High quality recommendations are highly needed along with specific practical advice for persons with schizophrenia, family members and health care professionals...
  42. doi request reprint Considering a frame of reference for physical activity research related to the cardiometabolic risk profile in schizophrenia
    Davy Vancampfort
    University Psychiatric Center, Catholic University Leuven, campus Kortenberg, Belgium
    Psychiatry Res 177:271-9. 2010
    ..More research is needed to assist in the practical development of effective evidence-based preventive and curative strategies in psychiatric services for metabolic syndrome in persons with schizophrenia...
  43. ncbi request reprint Physical activity correlates in persons with binge eating disorder: a systematic review
    Davy Vancampfort
    Department of Neurosciences, University Psychiatric Center Catholic University of Leuven, Kortenberg, Belgium Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium
    Eur Eat Disord Rev 22:1-8. 2014
    ..The only significant correlate with lower physical activity participation reported in more than one study was a negative body attitude. Further research is required to address this current gap in literature...
  44. doi request reprint Metabolic and cardiovascular adverse effects associated with antipsychotic drugs
    Marc De Hert
    University Psychiatric Center, Catholic University Leuven, Leuvensesteenweg 517, 3070 Kortenberg, Belgium marc de hert uc kortenberg be
    Nat Rev Endocrinol 8:114-26. 2012
    ....
  45. ncbi request reprint A systematic review of physical therapy interventions for patients with anorexia and bulemia nervosa
    Davy Vancampfort
    University Psychiatric Centre Catholic University Leuven, campus Kortenberg, Kortenberg, Belgium
    Disabil Rehabil 36:628-34. 2014
    ....
  46. pmc An impaired health related muscular fitness contributes to a reduced walking capacity in patients with schizophrenia: a cross-sectional study
    Davy Vancampfort
    University Psychiatric Centre Catholic University Leuven, campus Kortenberg, Kortenberg, Belgium
    BMC Psychiatry 13:5. 2013
    ..Secondly, we identified variables that could explain the variability in walking capacity and in health related muscular fitness in patients with schizophrenia...
  47. doi request reprint CNR1 gene and risk of the metabolic syndrome in patients with schizophrenia
    Weiping Yu
    University Psychiatric Center Campus Kortenberg, Katholieke University Leuven, Kortenberg, Belgium
    J Clin Psychopharmacol 33:186-92. 2013
    ..Further studies are needed to uncover the exact molecular basis for this association, which could provide novel treatment targets for the MetS...
  48. doi request reprint Associations between sedentary behaviour and metabolic parameters in patients with schizophrenia
    Davy Vancampfort
    University Psychiatric Centre Catholic University Leuven, campus Kortenberg, Kortenberg, Belgium
    Psychiatry Res 200:73-8. 2012
    ..A stepwise backward-elimination multivariate regression analysis demonstrated that sitting time is a significant predictor for BMI. Current results suggest patients with schizophrenia may benefit from reducing total sitting time...
  49. ncbi request reprint Metabolic control in patients with schizophrenia treated with amisulpride or olanzapine
    Joseph Peuskens
    UPC Katholieke Universiteit Leuven, campus Kortenberg, Kortenberg, Belgium
    Int Clin Psychopharmacol 22:145-52. 2007
    ..This should be taken into account in assessing risk-benefit of treatment options in schizophrenia...
  50. doi request reprint Effects of progressive muscle relaxation on state anxiety and subjective well-being in people with schizophrenia: a randomized controlled trial
    Davy Vancampfort
    University Psychiatric Centre Catholic University Leuven, campus Kortenberg, Kortenberg, Belgium
    Clin Rehabil 25:567-75. 2011
    ..To examine the efficacy of a single progressive muscle relaxation session compared with a control condition on state anxiety, psychological stress, fatigue and subjective well-being in patients with schizophrenia...
  51. ncbi request reprint Walking capacity is associated with health related quality of life and physical activity level in patients with schizophrenia: a preliminary report
    Ana Martín-Sierra
    University Psychiatric Centre K U Leuven, campus Kortenberg, Belgium
    Actas Esp Psiquiatr 39:211-6. 2011
    ..To examine walking capacity in patients with schizophrenia and the relation with quality of life and physical activity level...
  52. doi request reprint International Organization of Physical Therapy in Mental Health consensus on physical activity within multidisciplinary rehabilitation programmes for minimising cardio-metabolic risk in patients with schizophrenia
    Davy Vancampfort
    University Psychiatric Centre Catholic University Leuven, Kortenberg, Belgium
    Disabil Rehabil 34:1-12. 2012
    ..The aim of this paper is to improve physical activity (PA) within rehabilitation programmes for people with schizophrenia...
  53. doi request reprint Reliability, minimal detectable changes, practice effects and correlates of the 6-min walk test in patients with schizophrenia
    Davy Vancampfort
    University Psychiatric Center, Catholic University Leuven, campus Kortenberg, Kortenberg, Belgium
    Psychiatry Res 187:62-7. 2011
    ..The 6 MWT can be recommended for evaluating the functional exercise capacity in patients with schizophrenia. Some practice effect could however not be excluded...
  54. ncbi request reprint Metabolic abnormalities associated with second generation antipsychotics: fact or fiction? Development of guidelines for screening and monitoring
    Marc De Hert
    Universitair Centrum Sint Jozef, Catholic University Louvain, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Int Clin Psychopharmacol 21:S11-5. 2006
    ....
  55. doi request reprint Health related quality of life, physical fitness and physical activity participation in treatment-seeking obese persons with and without binge eating disorder
    Davy Vancampfort
    University Psychiatric Centre Catholic University Leuven, campus Kortenberg, Leuvensesteenweg 517, B 3070 Kortenberg, Belgium Faculty of Kinesiology and Rehabilitation Sciences, Catholic University Leuven, Tervuursevest 101, 3001 Leuven, Belgium Electronic address
    Psychiatry Res 216:97-102. 2014
    ..1±12.2) explained 47.1% of the variability in mental HRQL. The present findings suggest that the treatment of obese individuals with BED might benefit by giving more attention to HRQL, depressive symptoms and physical fitness. ..
  56. doi request reprint Age at onset of psychotic disorder: cannabis, BDNF Val66Met, and sex-specific models of gene-environment interaction
    Jeroen Decoster
    University Psychiatric Centre Catholic University Leuven, Kortenberg, Belgium
    Am J Med Genet B Neuropsychiatr Genet 156:363-9. 2011
    ..No compelling evidence was found that BDNF genotype is associated with age at onset of psychotic disorder in the absence of cannabis use...
  57. ncbi request reprint Evidence that the COMT(Val158Met) polymorphism moderates sensitivity to stress in psychosis: an experience-sampling study
    Ruud van Winkel
    University Psychiatric Center Katholieke Universiteit Leuven, Leuvensesteenweg, Kortenberg, Belgium
    Am J Med Genet B Neuropsychiatr Genet 147:10-7. 2008
    ....
  58. doi request reprint Increased ventral striatal CB1 receptor binding is related to negative symptoms in drug-free patients with schizophrenia
    Jenny Ceccarini
    Division of Nuclear Medicine, University Hospitals Leuven and Department of Imaging and Pathology, KU Leuven, Leuven, Belgium
    Neuroimage 79:304-12. 2013
    ..In SCZ-F patients, it is associated with negative symptoms and depression scores...
  59. doi request reprint Associations between perceived neighbourhood environmental attributes and self-reported sitting time in patients with schizophrenia: a pilot study
    Davy Vancampfort
    University Psychiatric Centre KU Leuven, campus Kortenberg, Department of Neurosciences KU Leuven, Kortenberg, Belgium Department of Rehabilitation Sciences KU Leuven, Leuven, Belgium Electronic address
    Psychiatry Res 215:33-8. 2014
    ..8%. Clinical practice guidelines should incorporate strategies targeting changes in sitting behaviours, from encouraging environmental changes to the availability of exercise equipment...
  60. doi request reprint The Cognitive Biases Questionnaire for Psychosis (CBQ-P) and the Davos Assessment of Cognitive Biases (DACOBS): validation in a Flemish sample of psychotic patients and healthy controls
    Tim Bastiaens
    UPC KULeuven Campus Kortenberg, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Schizophr Res 147:310-4. 2013
    ..Two new instruments on cognitive biases are evaluated: the Cognitive Biases Questionnaire for Psychosis and the Davos Assessment of Cognitive Biases Scale...
  61. doi request reprint The importance of self-determined motivation towards physical activity in patients with schizophrenia
    Davy Vancampfort
    University Psychiatric Centre, KU Leuven Campus Kortenberg, KU Leuven Department of Neurosciences, Leuvensesteenweg 517, B 3070 Kortenberg, Belgium KU Leuven Department of Rehabilitation Sciences, Tervuursevest 101, B 3001 Leuven, Belgium Electronic address
    Psychiatry Res 210:812-8. 2013
    ..05) regulations than inpatients. Our results suggest that patients' level of self-determination may play an important role in the adoption and maintenance of health promoting behaviors in patients with schizophrenia...
  62. ncbi request reprint Genetic association study of the P300 endophenotype in schizophrenia
    Jeroen Decoster
    Department of Psychiatry and Psychology, School for Mental Health and Neuroscience, EURON, Maastricht University Medical Centre, PO Box 616, 6200 MD Maastricht, The Netherlands
    Schizophr Res 141:54-9. 2012
    ..This study aims to examine associations between P300 and a range of candidate genetic variants, selected from either candidate gene studies or genome-wide association studies, in a large sample of patients with schizophrenia...
  63. pmc Incident somatic comorbidity after psychosis: results from a retrospective cohort study based on Flemish general practice data
    Carla Truyers
    Department of General Practice, Katholieke Universiteit Leuven, Leuven, Belgium
    BMC Fam Pract 12:132. 2011
    ..Many studies are performed in specialized settings with a strong focus on schizophrenia. Somatic comorbidity after psychosis is studied, using a general practice comorbidity registration network...
  64. doi request reprint Systematic review of the benefits of physical therapy within a multidisciplinary care approach for people with schizophrenia
    Davy Vancampfort
    Faculty of Kinesiology and Rehabilitation Sciences, Catholic University Leuven, Leuven, Belgium
    Phys Ther 92:11-23. 2012
    ..Although schizophrenia is the fifth leading cause of disability-adjusted life years worldwide in people aged 15 to 44 years, the clinical evidence of physical therapy as a complementary treatment remains largely unknown...
  65. ncbi request reprint Premorbid IQ as a predictor for the course of IQ in first onset patients with schizophrenia: a 10-year follow-up study
    Ruud van Winkel
    University Psychiatric Center Katholieke Universiteit Leuven, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    Schizophr Res 88:47-54. 2006
    ..Rather, catching up of cognitive function later in the course of the illness may take place in those whose deficits become apparent in the early phases of illness, whereas those with the most severe premorbid impairments remain stable...
  66. doi request reprint End-of-life (care) perspectives and expectations of patients with schizophrenia
    Kim Sweers
    University Psychiatric Centre campus Kortenberg KU Leuven, Kortenberg, Belgium
    Arch Psychiatr Nurs 27:246-52. 2013
    ..Schizophrenia is a disabling and life-shortening psychiatric disorder due to disease, medication, and lifestyle-related factors. It is therefore not unreasonable to assume that existential themes are important for these patients...
  67. pmc Metabolic syndrome in people with schizophrenia: a review
    Marc De Hert
    University Psychiatric Center, Catholic University Leuven, Leuvensesteenweg 517, 3070 Kortenberg, Belgium
    World Psychiatry 8:15-22. 2009
    ..The somatic treatments offered to people with severe and enduring mental illness should be at par with general health care in the non-psychiatrically ill population...
  68. ncbi request reprint Safe ECT in a patient with the Ehlers-Danlos syndrome
    Pascal Sienaert
    ECT Department, University Centre Sint Jozef, Leuvensesteenweg, Kortenberg, Belgium
    J ECT 19:230-3. 2003
    ..Even without specific measures to lower blood pressure, a course of ECT was finished without any complication...
  69. ncbi request reprint Comorbid somatic illnesses in patients with severe mental disorders: clinical, policy, and research challenges
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    J Clin Psychiatry 69:514-9. 2008
    ....
  70. ncbi request reprint Glucose abnormalities in a non-psychotic patient treated with risperidone
    Kristel Lauwers
    J Am Acad Child Adolesc Psychiatry 44:629-30. 2005
  71. ncbi request reprint Stereotypy in schizophrenia
    Manuel Morrens
    Collaborative Antwerp Psychiatric Research Institute CAPRI, Building A, Campus Drie Eiken, Universiteitsplein 1, B 2610 Antwerp Wilrijk, Belgium
    Schizophr Res 84:397-404. 2006
    ..We used a newly designed computerized version of the Zeigeversuch, the Stereotypy Test Apparatus (STA) to evaluate the evolution of STA performance through the course of the illness...
  72. ncbi request reprint Pharmacological treatment of severe dyslipidaemia in patients with schizophrenia
    Linda Hanssens
    Department of Epidemiology and Public Health, Nutrition and Metabolic Disorders CHU Sart Tilman, University Liege, Liege, Belgium
    Int Clin Psychopharmacol 22:43-9. 2007
    ..Statins proved effective in the management of dyslipidaemia in patients with schizophrenia treated with antipsychotics. More complex treatment may be required for associated metabolic disturbances...
  73. ncbi request reprint Usefulness of glycosylated haemoglobin (HbA1c) to screen for diabetes in patients with schizophrenia
    Linda Hanssens
    Schizophr Res 85:296-7. 2006
  74. ncbi request reprint Magnetization transfer imaging in chronic schizophrenia
    Aneta Antosik-Biernacka
    Department of Radiology, Medical University of Łódź, Łódź, Poland
    Med Sci Monit 12:MT17-21. 2006
    ..The aim of the study was to investigate whether MTI, analyzed on a voxel-by-voxel basis, could identify areas of abnormal magnetization transfer ratio (MTR) in patients with schizophrenia...
  75. ncbi request reprint The generic alternative in schizophrenia: opportunity or threat?
    Philippe Nuss
    Psychiatry Department, Hopital St Antoine, Paris 75012, France
    CNS Drugs 18:769-75. 2004
    ....
  76. ncbi request reprint The five-factor model of the Positive and Negative Syndrome Scale II: a ten-fold cross-validation of a revised model
    Mark van der Gaag
    Parnassia Psychiatric Institute, Oude Haagweg 353, The Hague, The Netherlands
    Schizophr Res 85:280-7. 2006
    ..Complex means that symptoms can have multiple factor loadings, because they have multiple causes, not because they are ill defined. Stable means that the complex structure is found repeatedly in validations...
  77. ncbi request reprint The five-factor model of the Positive and Negative Syndrome Scale I: confirmatory factor analysis fails to confirm 25 published five-factor solutions
    Mark van der Gaag
    Parnassia Psychiatric Institute, Oude Haagweg 353, The Hague, The Netherlands
    Schizophr Res 85:273-9. 2006
    ..The aim of this study was to test the goodness-of-fit of all previously published five-factor models of the Positive and Negative Syndrome Scale (PANSS)...