Research Topics
| H CelisSummaryAffiliation: Katholieke Universiteit Leuven Country: Belgium Publications
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Detail Information
Publications
Antihypertensive treatment based on home or office blood pressure--the THOP trialElly Den Hond
Study Coordinating Centre, Hypertension and Cardiovascular Rehabilitation Unit, Department of Molecular and Cardiovascular Research, University of Leuven, Leuven, Belgium
Blood Press Monit 9:311-4. 2004..CONCLUSIONS: The present findings support a stepwise strategy for the evaluation of blood pressure, in which self-measurement and ambulatory monitoring are complementary to conventional office blood pressure measurement...
Cardiovascular risk in white-coat and sustained hypertensive patientsHilde Celis
Study Coordinating Centre, Hypertension and Cardiovascular Rehabilitation Unit, Department of Molecular and Cardiovascular Research, University of Leuven, Leuven, Belgium
Blood Press 11:352-6. 2002..Although white-coat hypertension was less frequently associated with antihypertensive drug treatment during follow-up, it carried a significantly better prognosis than sustained hypertension...
Self-measurement of blood pressure at home in the management of hypertensionHilde Celis
Study Coordinating Center, Hypertension and Cardiovascular Rehabilitation Unit, Department of Molecular and Cardiovascular Research, University of Leuven, Leuven, Belgium
Clin Med Res 3:19-26. 2005..Until more prospective data become available, management of hypertension exclusively based on self-measurement of BP at home cannot be recommended...
Interaction between nonsteroidal anti-inflammatory drug intake and calcium-channel blocker-based antihypertensive treatment in the Syst-Eur trialH Celis
The Hypertensie en Cardiovasculaire Revalidatie Eenheid, Departement Moleculair en Cardiovasculair Onderzoek, Katholieke Universiteit Leuven, Leuven, Belgium
J Hum Hypertens 15:613-8. 2001....
Risk and benefit of treatment of isolated systolic hypertension in the elderly: evidence from the Systolic Hypertension in Europe TrialH Celis
Studiecoördinatiecentrum, Laboratorium Hypertensie, Campus Gasthuisbrg, Leuven, Belgium
Curr Opin Cardiol 16:342-8. 2001..Finally, a meta-analysis partly based on Syst-Eur data showed that in older hypertensive patients pulse pressure and not mean pressure is the major determinant of cardiovascular risk...
Subgroup and per-protocol analysis of the randomized European Trial on Isolated Systolic Hypertension in the ElderlyJ A Staessen
Department of Cardiovascular and Molecular Research, University of Leuven, Belgium
Arch Intern Med 158:1681-91. 1998....
Dihydropyridine calcium-channel blockers for antihypertensive treatment in older patients--evidence from the Systolic Hypertension in Europe TrialJ A Staessen
, Laboratorium Hypertensie, Campus Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium
S Afr Med J 91:1060-8. 2001..CONCLUSION: Stepwise antihypertensive drug treatment, starting with the dihydropiridine calcium-channel blocker nitrendipine, improves prognosis in elderly patients with isolated systolic hypertension...
Antihypertensive treatment based on conventional or ambulatory blood pressure measurement. A randomized controlled trial. Ambulatory Blood Pressure Monitoring and Treatment of Hypertension InvestigatorsJ A Staessen
Hypertensie en Cardiovasculaire Revalidatie Eenheid, Departement voor Moleculair en Cardiovasculaire Onderzoek, Katholieke Universiteit Leuven, Belgium
JAMA 278:1065-72. 1997..Ambulatory blood pressure (ABP) monitoring is used increasingly in clinical practice, but how it affects treatment of blood pressure has not been determined...
Reference values for self-recorded blood pressure: a meta-analysis of summary dataL Thijs
Department of Molecular and Cardiovascular Research, University of Leuven, Belgium
Arch Intern Med 158:481-8. 1998..The latter 2 methods were applied in untreated subjects not selected on the basis of their blood pressure...
On-treatment diastolic blood pressure and prognosis in systolic hypertensionRobert H Fagard
Hypertension and Cardiovascular Rehabilitation Unit, University of Leuven, B 3000 Leuven, Belgium
Arch Intern Med 167:1884-91. 2007..We examined the association between on-treatment diastolic BP, mortality, and cardiovascular events in the prospective placebo-controlled Systolic Hypertension in Europe Trial...
OASIS-HT: design of a pharmacogenomic dose-finding studyJan A Staessen
Department of Molecular and Cardiovascular Research, Hypertension and Cardiovascular Rehabilitation Unit, Study Coordinating Centre, University of Leuven, Belgium
Pharmacogenomics 6:755-75. 2005..To our knowledge, OASIS-HT is the first Phase II dose-finding study in which a genetic hypothesis is driving primary and secondary end points...
Prognostic significance of electrocardiographic voltages and their serial changes in elderly with systolic hypertensionRobert H Fagard
Hypertension and Cardiovascular Rehabilitation Unit, University of Leuven, Leuven, Belgium
Hypertension 44:459-64. 2004..86; P< or =0.05), but not of stroke or mortality. In conclusion, electrocardiographic voltages at baseline and their serial changes during follow-up predict subsequent events in older patients with systolic hypertension...
Prognostic significance of various characteristics of out-of-the-office blood pressureRobert H Fagard
J Hypertens 22:1663-6. 2004
Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe TrialJan A Staessen
J Hypertens 22:847-57. 2004..Immediate compared with delayed treatment prevented 17 strokes or 25 major cardiovascular events per 1000 patients followed up for 6 years. These findings underscore the necessity of early treatment of isolated systolic hypertension...
Antihypertensive treatment based on blood pressure measurement at home or in the physician's office: a randomized controlled trialJan A Staessen
Study Coordinating Centre, Hypertension and Cardiovascular Rehabilitation Unit, Department of Molecular and Cardiovascular Research, University of Leuven, Leuven, Belgium
JAMA 291:955-64. 2004..Self-measurement of blood pressure is increasingly used in clinical practice, but how it affects the treatment of hypertension requires further study...
Self-measured versus ambulatory blood pressure in the diagnosis of hypertensionElly Den Hond
Study Coordinating Centre, Hypertension and Cardiovascular Rehabilitation Unit, Department of Molecular and Cardiovascular Research, Katholieke Universiteit Leuven, Belgium
J Hypertens 21:717-22. 2003..We examined to what extent self-measurement of blood pressure at home (HBP) can be an alternative to ambulatory monitoring (ABP) to diagnose white-coat hypertension...
Determinants of white-coat syndrome assessed by ambulatory blood pressure or self-measured home blood pressureElly Den Hond
Study Coordinating Centre, Hypertension and Cardiovascular Rehabilitation Unit, Katholieke Universiteit Leuven, Leuven, Belgium
Blood Press Monit 8:37-40. 2003..Gender, age, smoking, race, and body mass index have been reported to determine the ambulatory white-coat effect (WCE) and white-coat hypertension (WCH)...
Daytime and nighttime blood pressure as predictors of death and cause-specific cardiovascular events in hypertensionRobert H Fagard
Hypertension and Cardiovascular Rehabilitation Unit, Faculty of Medicine, University of Leuven, Belgium
Hypertension 51:55-61. 2008....
Environmental exposure to cadmium and risk of cancer: a prospective population-based studyTim Nawrot
Study Coordinating Centre, Hypertension and Cardiovascular Rehabilitation Unit, Department of Cardiovascular Diseases, University of Leuven, Leuven, Belgium
Lancet Oncol 7:119-26. 2006..57 (1.11-2.24, p=0.012) for a doubling of cadmium concentration in soil. INTERPRETATION: Historical pollution from non-ferrous smelters continues to present a serious health hazard, necessitating targeted preventive measures...
