Jean-Jacques Cassiman

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. ncbi request reprint Research network: EuroGentest--a European Network of Excellence aimed at harmonizing genetic testing services
    Jean Jacques Cassiman
    Center for Human Genetics, University of Leuven, Campus Gasthuisberg, O and N 6, Herestraat 49, Leuven B 3000, Belgium
    Eur J Hum Genet 13:1103-5. 2005
  2. ncbi request reprint Belgian population data for 15 STR loci (AmpFlSTR SGM Plus and AmpFlSTR profiler PCR amplification kit)
    Ronny Decorte
    Laboratory for Forensic Genetics and Molecular Archaeology, K U Leuven, Campus Gasthuisberg O and N, Herestraat 49, B 3000 Leuven, Belgium
    Forensic Sci Int 139:211-3. 2004
  3. ncbi request reprint Allele frequency data for 19 short tandem repeats (PowerPlex 16 and FFFl) in a Belgian population sample
    Ronny Decorte
    Laboratory for Forensic Genetics and Molecular Archaeology, K U Leuven, Campus Gasthuisberg O and N, Herestraat 49 bus 602, B 3000 Leuven, Belgium
    J Forensic Sci 51:436-7. 2006
  4. ncbi request reprint Pathogenic mutations and rare variants of the APC gene identified in 75 Belgian patients with familial adenomatous polyposis by fluorescent enzymatic mutation detection (EMD)
    Genevieve Michils
    Center for Human Genetics, University of Leuven, Leuven, Belgium
    Eur J Hum Genet 10:505-10. 2002
  5. ncbi request reprint Mutations of the cystic fibrosis gene and intermediate sweat chloride levels in children
    Patrick Lebecque
    Department of Pediatrics, Center for Human Genetics, Gasthuisberg, Belgium
    Am J Respir Crit Care Med 165:757-61. 2002
  6. ncbi request reprint Distribution of human beta-defensin polymorphisms in various control and cystic fibrosis populations
    Anne Vankeerberghen
    Department of Human Genetics, KULeuven, Herestraat 49, O and N6, 3000 Louvain, Belgium
    Genomics 85:574-81. 2005
  7. ncbi request reprint Upregulation of Wilms' tumor gene 1 (WT1) in desmoid tumors
    Saeid Amini Nik
    Center for Human Genetics, University of Leuven, Leuven, Belgium
    Int J Cancer 114:202-8. 2005
  8. ncbi request reprint Diversity at eight polymorphic Alu insertion loci in Chinese populations shows evidence for European admixture in an ethnic minority population from northwest China
    Feng Xia Xiao
    Center for Human Genetics, University of Leuven, Belgium
    Hum Biol 74:555-68. 2002
  9. ncbi request reprint Towards quality assurance and harmonization of genetic testing services in the European Union
    Dolores Ibarreta
    European Commission, Joint Research Center, Institute for Prospective Technological Studies, Edificio Expo, E 41092 Seville, Spain
    Nat Biotechnol 22:1230-5. 2004
  10. ncbi request reprint Y-chromosomal STR haplotypes in a Belgian population sample and identification of a micro-variant with a flanking site mutation at DYS19
    Kris De Maesschalck
    Laboratory for Forensic Genetics and Molecular Archaeology, K U Leuven, Campus Gasthuisberg O and N, Herestraat 49 bus 602, B 3000 Leuven, Belgium
    Forensic Sci Int 152:89-94. 2005

Collaborators

  • Ronny Decorte
  • G Matthijs
  • Silke Jansen
  • Tim Becker
  • Jorg Schmidtke
  • S Ayme
  • Harry Cuppens
  • Nancy Vanderheyden
  • Sabine Tejpar
  • Richard Hayhurst
  • Frauke Stanke
  • Anne Vankeerberghen
  • Saeid Amini Nik
  • Kris De Maesschalck
  • Elisabeth Dequeker
  • Dolores Ibarreta
  • Feng Xia Xiao
  • Griet Vanpoucke
  • Patrick Lebecque
  • Genevieve Michils
  • Ahnly Mai
  • Anja Gilissen
  • Thomas F Wienker
  • Vinod Kumar
  • Jennifer Yarden
  • Benny Siebert
  • Burkhard Tummler
  • David W Ussery
  • Dragica Radojkovic
  • Elisabeth Vanhoutte
  • Francesco Salvatore
  • Bernadette Van der Schueren
  • NoĆ©mi Van Hul
  • Ali Jadidizadeh
  • Vera Vavrova
  • Olga Scudiero
  • Daniela Zemkova
  • Peter Hohenstein
  • Hilde Nuytten
  • Giuseppe Castaldo
  • Katleen Knaepen
  • Milan Macek
  • Kris De Boeck
  • Charles E Patek
  • Adriana Bastidas
  • Pier Franco Pignatti
  • Kim Van Dam
  • Rachel L Berry
  • Robert Elles
  • Emilio Rodriguez-Cerezo
  • Eric Legius
  • Friedel Nollet
  • Teresinha Leal
  • Jun Fang Yang
  • Christiane De Boeck
  • Martine Jaspers
  • Jean Pierre Fryns
  • Eric Van Cutsem
  • Frans van Roy

Detail Information

Publications16

  1. ncbi request reprint Research network: EuroGentest--a European Network of Excellence aimed at harmonizing genetic testing services
    Jean Jacques Cassiman
    Center for Human Genetics, University of Leuven, Campus Gasthuisberg, O and N 6, Herestraat 49, Leuven B 3000, Belgium
    Eur J Hum Genet 13:1103-5. 2005
  2. ncbi request reprint Belgian population data for 15 STR loci (AmpFlSTR SGM Plus and AmpFlSTR profiler PCR amplification kit)
    Ronny Decorte
    Laboratory for Forensic Genetics and Molecular Archaeology, K U Leuven, Campus Gasthuisberg O and N, Herestraat 49, B 3000 Leuven, Belgium
    Forensic Sci Int 139:211-3. 2004
    ..The allele and genotype distributions for 15 STR loci included in the AmpFlSTR SGM Plus and AmpFlSTR Profiler kits (Applied Biosystems, Foster City, USA) were determined in a sample of 222 unrelated individuals of Belgian origin...
  3. ncbi request reprint Allele frequency data for 19 short tandem repeats (PowerPlex 16 and FFFl) in a Belgian population sample
    Ronny Decorte
    Laboratory for Forensic Genetics and Molecular Archaeology, K U Leuven, Campus Gasthuisberg O and N, Herestraat 49 bus 602, B 3000 Leuven, Belgium
    J Forensic Sci 51:436-7. 2006
  4. ncbi request reprint Pathogenic mutations and rare variants of the APC gene identified in 75 Belgian patients with familial adenomatous polyposis by fluorescent enzymatic mutation detection (EMD)
    Genevieve Michils
    Center for Human Genetics, University of Leuven, Leuven, Belgium
    Eur J Hum Genet 10:505-10. 2002
    ....
  5. ncbi request reprint Mutations of the cystic fibrosis gene and intermediate sweat chloride levels in children
    Patrick Lebecque
    Department of Pediatrics, Center for Human Genetics, Gasthuisberg, Belgium
    Am J Respir Crit Care Med 165:757-61. 2002
    ..4 mM, p < 0.05). The nasal potential difference was abnormal in five of the nine subjects tested. In this study, 23% of children displaying intermediate sweat chloride levels were found to carry a putative mutation on both CFTR genes...
  6. ncbi request reprint Distribution of human beta-defensin polymorphisms in various control and cystic fibrosis populations
    Anne Vankeerberghen
    Department of Human Genetics, KULeuven, Herestraat 49, O and N6, 3000 Louvain, Belgium
    Genomics 85:574-81. 2005
    ..No association with the age of first infection by Pseudomonas aeruginosa or with the FEV1 percentage at the age of 11-13 years could be found...
  7. ncbi request reprint Upregulation of Wilms' tumor gene 1 (WT1) in desmoid tumors
    Saeid Amini Nik
    Center for Human Genetics, University of Leuven, Leuven, Belgium
    Int J Cancer 114:202-8. 2005
    ..These results show that the wild-type WT1 gene is strongly overexpressed in beta-catenin mutant desmoid tumors and may play a role in tumorigenesis of desmoid tumors, similar to what has been suggested in some epithelial malignancies...
  8. ncbi request reprint Diversity at eight polymorphic Alu insertion loci in Chinese populations shows evidence for European admixture in an ethnic minority population from northwest China
    Feng Xia Xiao
    Center for Human Genetics, University of Leuven, Belgium
    Hum Biol 74:555-68. 2002
    ..This study also provides further support for the "out-of-Africa" hypothesis of modern human evolution in East Asia...
  9. ncbi request reprint Towards quality assurance and harmonization of genetic testing services in the European Union
    Dolores Ibarreta
    European Commission, Joint Research Center, Institute for Prospective Technological Studies, Edificio Expo, E 41092 Seville, Spain
    Nat Biotechnol 22:1230-5. 2004
  10. ncbi request reprint Y-chromosomal STR haplotypes in a Belgian population sample and identification of a micro-variant with a flanking site mutation at DYS19
    Kris De Maesschalck
    Laboratory for Forensic Genetics and Molecular Archaeology, K U Leuven, Campus Gasthuisberg O and N, Herestraat 49 bus 602, B 3000 Leuven, Belgium
    Forensic Sci Int 152:89-94. 2005
    ..Ninety-nine different haplotypes were observed with an overall haplotype diversity of 0.997...
  11. ncbi request reprint EuroGentest standing up to scrutiny--first year demonstrates good progress harmonizing community approaches
    Richard Hayhurst
    J Appl Genet 47:5-7. 2006
  12. ncbi request reprint Identification and sequence analysis of discordant phenotypes between AmpFlSTR SGM Plus and PowerPlex 16
    Nancy Vanderheyden
    Laboratory of Forensic Genetics and Molecular Archaeology, K U Leuven, Campus Gasthuisberg O and N, Herestraat 49 bus 602, 3000 Leuven, Belgium
    Int J Legal Med 121:297-301. 2007
    ..58% in our study), it is suggested that appropriate measures should be taken for database comparisons and that allelic dropout should be further investigated by sequence analysis and be reported to the forensic community...
  13. ncbi request reprint Cystic fibrosis
    Harry Cuppens
    Department of Human Genetics, Katholieke Universiteit Leuven, Belgium
    Methods Mol Med 92:221-44. 2004
  14. ncbi request reprint The TNFalpha receptor TNFRSF1A and genes encoding the amiloride-sensitive sodium channel ENaC as modulators in cystic fibrosis
    Frauke Stanke
    Department of Pediatrics, OE6711, Hannover Medical School, Carl Neuberg Str 1, 30625, Hannover, Germany
    Hum Genet 119:331-43. 2006
    ....
  15. ncbi request reprint The human alphaE-catenin gene CTNNA1: mutational analysis and rare occurrence of a truncated splice variant
    Griet Vanpoucke
    Molecular Cell Biology Unit, Department for Molecular Biomedical Research, Flanders Interuniversity Institute for Biotechnology V I B, Ghent University, Ledeganckstraat 35, B 9000, Ghent, Belgium
    Biochim Biophys Acta 1574:262-8. 2002
    ..Thus, contrary to previous notions, alternative splicing with in-frame insertion nearby the C-terminal end of the protein is not a general feature for all members of the alpha-catenin/vinculin family...
  16. doi request reprint Patenting and licensing in genetic testing
    S Ayme
    Eur J Hum Genet 16:405-11. 2008
    ..Finally, the ESHG is calling upon all stakeholders to start the process of developing a code of conduct for partners with patents, covering ethical aspects as well as smooth licensing arrangements...