Gunnar M Buyse

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. ncbi request reprint Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring
    G Buyse
    Department of Pediatric Neurology, University Hospitals Leuven, Belgium
    Neurology 60:1679-81. 2003
  2. ncbi request reprint CINRG pilot trial of oxatomide in steroid-naïve Duchenne muscular dystrophy
    Gunnar M Buyse
    University Hospitals KU Leuven, Leuven, Herestraat 49, B 3000 Leuven, Belgium
    Eur J Paediatr Neurol 11:337-40. 2007
  3. doi request reprint Effects of glucocorticoids and idebenone on respiratory function in patients with duchenne muscular dystrophy
    Gunnar M Buyse
    Department of Child Neurology, University Hospitals Leuven, Belgium
    Pediatr Pulmonol 48:912-20. 2013
  4. doi request reprint Idebenone as a novel, therapeutic approach for Duchenne muscular dystrophy: results from a 12 month, double-blind, randomized placebo-controlled trial
    Gunnar M Buyse
    Child Neurology, University Hospitals Leuven, Leuven, Belgium
    Neuromuscul Disord 21:396-405. 2011
  5. doi request reprint Regulated granule trafficking in platelets and neurons: a common molecular machinery
    Christophe Goubau
    Center for Molecular and Vascular Biology, University of Leuven, Leuven, Belgium
    Eur J Paediatr Neurol 17:117-25. 2013
  6. pmc Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance
    Gunnar M Buyse
    Department of Pediatric Neurology, University Hospitals Leuven, Herestraat, Leuven, Belgium
    Eur Heart J 30:116-24. 2009
  7. doi request reprint Homozygosity for aquaporin 7 G264V in three unrelated children with hyperglyceroluria and a mild platelet secretion defect
    Christophe Goubau
    Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, Leuven, Belgium
    Genet Med 15:55-63. 2013

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring
    G Buyse
    Department of Pediatric Neurology, University Hospitals Leuven, Belgium
    Neurology 60:1679-81. 2003
    ..Idebenone reduced erythrocyte protoporphyrin IX levels in five of six patients with elevated baseline levels; however, changes did not consistently relate to cardiac improvement...
  2. ncbi request reprint CINRG pilot trial of oxatomide in steroid-naïve Duchenne muscular dystrophy
    Gunnar M Buyse
    University Hospitals KU Leuven, Leuven, Herestraat 49, B 3000 Leuven, Belgium
    Eur J Paediatr Neurol 11:337-40. 2007
    ..A modest mitigation of strength deterioration over time cannot be excluded...
  3. doi request reprint Effects of glucocorticoids and idebenone on respiratory function in patients with duchenne muscular dystrophy
    Gunnar M Buyse
    Department of Child Neurology, University Hospitals Leuven, Belgium
    Pediatr Pulmonol 48:912-20. 2013
    ..The impact of standard care glucocorticoids on respiratory function will have to be considered in the planning of future interventional trials in DMD...
  4. doi request reprint Idebenone as a novel, therapeutic approach for Duchenne muscular dystrophy: results from a 12 month, double-blind, randomized placebo-controlled trial
    Gunnar M Buyse
    Child Neurology, University Hospitals Leuven, Leuven, Belgium
    Neuromuscul Disord 21:396-405. 2011
    ..042 for PEF percent predicted). Limitations of this study were the small sample size, and a skewed age distribution between treatment groups. Data from this study provided the basis for the planning of a confirmatory study...
  5. doi request reprint Regulated granule trafficking in platelets and neurons: a common molecular machinery
    Christophe Goubau
    Center for Molecular and Vascular Biology, University of Leuven, Leuven, Belgium
    Eur J Paediatr Neurol 17:117-25. 2013
    ..This review provides evidence that platelet research can be expanded from traditional studies of isolated thrombopathies to the field of neuropathologies that include a platelet secretion defect...
  6. pmc Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance
    Gunnar M Buyse
    Department of Pediatric Neurology, University Hospitals Leuven, Herestraat, Leuven, Belgium
    Eur Heart J 30:116-24. 2009
    ..We have performed such a trial of SNT-MC17/idebenone in the mdx mouse model of DMD, based on the drug's potential to improve mitochondrial respiratory chain function and reduce oxidative stress...
  7. doi request reprint Homozygosity for aquaporin 7 G264V in three unrelated children with hyperglyceroluria and a mild platelet secretion defect
    Christophe Goubau
    Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, Leuven, Belgium
    Genet Med 15:55-63. 2013
    ..AQP7-deficient mice develop obesity, insulin resistance, and hyperglyceroluria. However, AQP7's pathophysiologic role in humans is not yet known...