Research Topics
| Katleen BroosSummaryAffiliation: Katholieke Universiteit Leuven Country: Belgium Publications
| Collaborators
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Detail Information
Publications
Platelets at work in primary hemostasisKatleen Broos
Laboratory for Thrombosis Research, IRF Life Sciences, KU Leuven Campus Kortrijk, Belgium
Blood Rev 25:155-67. 2011..With this review, we intend to give an integrated survey of the platelet response to vascular injury in normal hemostasis...
Blood platelet biochemistryKatleen Broos
Laboratory for Thrombosis Research, IRF Life Sciences, KU Leuven Campus Kortrijk, Kortrijk, Belgium
Thromb Res 129:245-9. 2012..This review intends to give a comprehensive overview of the currently established main mechanisms in platelet function...
Platelet physiology and antiplatelet agentsTim Thijs
Laboratory for Thrombosis Research, KU Leuven Campus Kortrijk, Kortrijk, Belgium
Clin Chem Lab Med 48:S3-13. 2010..A thorough understanding of these pathways allows explanation of the mechanism of action of existing antiplatelet agents, but also helps to identify targets for novel drug development...
Antiplatelet drugsSimon F De Meyer
Laboratory for Thrombosis Research, IRC, KU Leuven Campus Kortrijk, Kortrijk, Belgium
Br J Haematol 142:515-28. 2008..For each stage, novel experimental targets and clinically established antiplatelet strategies will be reviewed. Limitations and possible benefits will be discussed for each target...
Development of a high-throughput ELISA assay for platelet function testing using platelet-rich plasma or whole bloodIsabelle Salles
Laboratory for Thrombosis Research, KU Leuven Campus Kortrijk, Kortrijk, Belgium
Thromb Haemost 104:392-401. 2010..Finally, we demonstrated that the platelet ELISA assay can not only be used in platelet-rich plasma but also in whole blood; it now awaits large scale studies to assess its full screening and diagnostic values...
Platelet adhesion to collagenBenedicte P Nuyttens
Laboratory for Thrombosis Research, KU Leuven Campus Kortrijk, Belgium
Thromb Res 127:S26-9. 2011..In this review, we summarize the current knowledge on the individual roles and structure-function relationships of these main platelet adhesion receptors...
Identification of a small molecule that modulates platelet glycoprotein Ib-von Willebrand factor interactionKatleen Broos
Laboratory for Thrombosis Research, Katholieke Universiteit Leuven, Kortrijk, Belgium
J Biol Chem 287:9461-72. 2012....
Model systems of genetically modified plateletsTim Thijs
Laboratory for Thrombosis Research, KU Leuven Campus Kortrijk, Kortrijk, Belgium
Blood 119:1634-42. 2012..Finally, we highlight the latest developments in genetic engineering techniques and their possible application in platelet research...
