Steven Boonen

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. doi Once-yearly zoledronic acid in older men compared with women with recent hip fracture
    Steven Boonen
    Center for Musculoskeletal Research, Leuven University, Leuven, Belgium
    J Am Geriatr Soc 59:2084-90. 2011
  2. pmc Efficacy and safety of a once-yearly intravenous zoledronic acid 5 mg for fracture prevention in elderly postmenopausal women with osteoporosis aged 75 and older
    Steven Boonen
    Leuven University Centre for Metabolic Bone Diseases and Division of Geriatric Medicine, University of Leuven, Leuven, Belgium
    J Am Geriatr Soc 58:292-9. 2010
  3. doi Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-alpha
    Filip Callewaert
    Laboratory for Experimental Medicine and Endocrinology, Department of Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    FASEB J 23:232-40. 2009
  4. doi Fall prediction according to nurses' clinical judgment: differences between medical, surgical, and geriatric wards
    Koen Milisen
    Centre for Health Services and Nursing Research, KU Leuven, Leuven, Belgium
    J Am Geriatr Soc 60:1115-21. 2012
  5. pmc Time to onset of antifracture efficacy and year-by-year persistence of effect of zoledronic acid in women with osteoporosis
    Steven Boonen
    University of Leuven, Leuven, Belgium
    J Bone Miner Res 27:1487-93. 2012
  6. doi Fracture risk and zoledronic acid therapy in men with osteoporosis
    Steven Boonen
    Katholieke Universiteit Leuven, Leuven, Belgium
    N Engl J Med 367:1714-23. 2012
  7. doi Androgen receptor disruption increases the osteogenic response to mechanical loading in male mice
    Filip Callewaert
    Center for Musculoskeletal Research, Department of Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    J Bone Miner Res 25:124-31. 2010
  8. doi Novel insights in the regulation and mechanism of androgen action on bone
    Mieke Sinnesael
    Clinical and Experimental Endocrinology, Department of Experimental Medicine, KU Leuven, Leuven, Belgium
    Curr Opin Endocrinol Diabetes Obes 20:240-4. 2013
  9. doi Sexual dimorphism in cortical bone size and strength but not density is determined by independent and time-specific actions of sex steroids and IGF-1: evidence from pubertal mouse models
    Filip Callewaert
    Center for Musculoskeletal Research, Leuven University Department of Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    J Bone Miner Res 25:617-26. 2010
  10. doi Fast and accurate specimen-specific simulation of trabecular bone elastic modulus using novel beam-shell finite element models
    Jef Vanderoost
    Division of Biomechanics, Department of Mechanical Engineering, K U Leuven, Leuven, Belgium
    J Biomech 44:1566-72. 2011

Detail Information

Publications57

  1. doi Once-yearly zoledronic acid in older men compared with women with recent hip fracture
    Steven Boonen
    Center for Musculoskeletal Research, Leuven University, Leuven, Belgium
    J Am Geriatr Soc 59:2084-90. 2011
    ....
  2. pmc Efficacy and safety of a once-yearly intravenous zoledronic acid 5 mg for fracture prevention in elderly postmenopausal women with osteoporosis aged 75 and older
    Steven Boonen
    Leuven University Centre for Metabolic Bone Diseases and Division of Geriatric Medicine, University of Leuven, Leuven, Belgium
    J Am Geriatr Soc 58:292-9. 2010
    ..To determine the efficacy of once-yearly intravenous zoledronic acid (ZOL) 5 mg in reducing risk of clinical vertebral, nonvertebral, and any clinical fractures in elderly osteoporotic postmenopausal women...
  3. doi Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-alpha
    Filip Callewaert
    Laboratory for Experimental Medicine and Endocrinology, Department of Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    FASEB J 23:232-40. 2009
    ..ERalpha activation alone is sufficient for the regulation of fat mass. Our findings clearly define the relative importance of AR and ERalpha signaling on trabecular and cortical bone mass as well as body composition in male mice...
  4. doi Fall prediction according to nurses' clinical judgment: differences between medical, surgical, and geriatric wards
    Koen Milisen
    Centre for Health Services and Nursing Research, KU Leuven, Leuven, Belgium
    J Am Geriatr Soc 60:1115-21. 2012
    ..To assess the value of nurses' clinical judgment (NCJ) in predicting hospital inpatient falls...
  5. pmc Time to onset of antifracture efficacy and year-by-year persistence of effect of zoledronic acid in women with osteoporosis
    Steven Boonen
    University of Leuven, Leuven, Belgium
    J Bone Miner Res 27:1487-93. 2012
    ..097). This analysis shows that zoledronic acid offered significant protection from clinical fractures as early as 12 months. When administered annually, its beneficial effects persisted for at least 3 years...
  6. doi Fracture risk and zoledronic acid therapy in men with osteoporosis
    Steven Boonen
    Katholieke Universiteit Leuven, Leuven, Belgium
    N Engl J Med 367:1714-23. 2012
    ..Fractures in men are a major health issue, and data on the antifracture efficacy of therapies for osteoporosis in men are limited. We studied the effect of zoledronic acid on fracture risk among men with osteoporosis...
  7. doi Androgen receptor disruption increases the osteogenic response to mechanical loading in male mice
    Filip Callewaert
    Center for Musculoskeletal Research, Department of Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    J Bone Miner Res 25:124-31. 2010
    ..In conclusion, AR but not ERalpha activation limits the osteogenic response to loading in male mice possibly via an effect on WNT signaling...
  8. doi Novel insights in the regulation and mechanism of androgen action on bone
    Mieke Sinnesael
    Clinical and Experimental Endocrinology, Department of Experimental Medicine, KU Leuven, Leuven, Belgium
    Curr Opin Endocrinol Diabetes Obes 20:240-4. 2013
    ..This review provides an update on the associations of testosterone, estrogens, sex hormone binding globulin, GH-IGF-I, osteocalcin and mechanical loading with relevance to skeletal health...
  9. doi Sexual dimorphism in cortical bone size and strength but not density is determined by independent and time-specific actions of sex steroids and IGF-1: evidence from pubertal mouse models
    Filip Callewaert
    Center for Musculoskeletal Research, Leuven University Department of Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    J Bone Miner Res 25:617-26. 2010
    ..In females, estrogens limit bone size during early puberty. These longitudinal findings in mice provide strong evidence that skeletal dimorphism is determined by independent and time-specific effects of sex steroids and IGF-1...
  10. doi Fast and accurate specimen-specific simulation of trabecular bone elastic modulus using novel beam-shell finite element models
    Jef Vanderoost
    Division of Biomechanics, Department of Mechanical Engineering, K U Leuven, Leuven, Belgium
    J Biomech 44:1566-72. 2011
    ..It allows performing detailed parametric analyses that cover the entire spectrum of trabecular bone microstructures...
  11. doi Androgen receptor (AR) in osteocytes is important for the maintenance of male skeletal integrity: evidence from targeted AR disruption in mouse osteocytes
    Mieke Sinnesael
    Clinical and Experimental Endocrinology, Department of Experimental Medicine, KU Leuven, Leuven, Belgium
    J Bone Miner Res 27:2535-43. 2012
    ..These findings provide evidence for a direct role of androgens in the maintenance of trabecular bone through actions of the AR in osteocytes...
  12. doi Influence of bone remodelling rate on quantitative ultrasound parameters at the calcaneus and DXA BMDa of the hip and spine in middle-aged and elderly European men: the European Male Ageing Study (EMAS)
    Steven Boonen
    Division of Geriatric Medicine and Centre for Metabolic Bone Diseases, Katholieke Universiteit Leuven, UZ Leuven Campus Gasthuisberg, Leuven, Belgium
    Eur J Endocrinol 165:977-86. 2011
    ..To assess the influence of sex hormones on markers of bone turnover and to explore the association between these markers and bone health in middle-aged and elderly European men...
  13. doi The effects of whole-body vibration training and vitamin D supplementation on muscle strength, muscle mass, and bone density in institutionalized elderly women: a 6-month randomized, controlled trial
    Sabine M P Verschueren
    Division of Musculoskeletal Rehabilitation, Department of Rehabilitation Sciences and, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    J Bone Miner Res 26:42-9. 2011
    ..A higher dose of 1600 IU of vitamin D does not provide additional musculoskeletal benefit in this population compared with conventional doses...
  14. doi Androgens and bone
    Dirk Vanderschueren
    Bone Research Unit, Laboratory for Experimental Medicine and Endocrinology, Department of Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    Curr Opin Endocrinol Diabetes Obes 15:250-4. 2008
    ..Therefore, some of the most recent findings of skeletal estrogen action relevant for male skeletal physiology will also be discussed...
  15. doi Clinical changes in older adults during hospitalization: responsiveness of the interRAI acute care instrument
    Nathalie I H Wellens
    Department of Public Health and Primary Care, Center for Health Services and Nursing Research, KU Leuven, Leuven, Belgium
    J Am Geriatr Soc 61:799-804. 2013
    ..To evaluate the responsiveness of the Minimum Data Set interRAI Acute Care (AC), a comprehensive geriatric assessment system, to detect clinical changes in patient status during hospital stays...
  16. doi Preventing delirium in older adults with recent hip fracture through multidisciplinary geriatric consultation
    Mieke Deschodt
    Center for Health Services and Nursing Research, KU Leuven, Leuven, Belgium
    J Am Geriatr Soc 60:733-9. 2012
    ....
  17. doi Osteoporosis in men
    Evelien Gielen
    Leuven University, Division of Geriatric Medicine, Leuven, Belgium
    Best Pract Res Clin Endocrinol Metab 25:321-35. 2011
    ..In men, evidence-based data on the efficacy of pharmacologic interventions in reducing fracture risk are convincing but not conclusive. In particular, bisphosphonates and teriparatide seem to be as effective in men as in women...
  18. ncbi Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in growing male mice: a study in the androgen receptor knockout mouse model
    Katrien Venken
    Laboratory for Experimental Medicine and Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium
    J Bone Miner Res 21:576-85. 2006
    ..AR activation dominates normal trabecular bone development and cortical bone modeling in male mice. Moreover, optimal periosteal bone expansion is only observed in the presence of both AR and ER activation...
  19. doi Convergent validity of the Cognitive Performance Scale of the interRAI acute care and the mini-mental state examination
    Nathalie I H Wellens
    Department of Public Health, Center for Health Services and Nursing Research, KU Leuven, Leuven, Belgium
    Am J Geriatr Psychiatry 21:636-45. 2013
    ..We evaluated the performance of the interRAI Acute Care in identifying cognitive impairment among patients hospitalized on acute geriatric wards...
  20. doi Effects of fitness and vibration training on muscle quality: a 1-year postintervention follow-up in older men
    Eva Kennis
    Physical Activity, Sports and Health Research Group, Department of Kinesiology, Katholieke Universiteit Leuven, Leuven, Belgium
    Arch Phys Med Rehabil 94:910-8. 2013
    ..To evaluate the residual effects of fitness and whole-body vibration (WBV) training in older men 1 year after completion of the interventions...
  21. doi Renal safety of annual zoledronic acid infusions in osteoporotic postmenopausal women
    Steven Boonen
    Leuven University Center for Metabolic Bone Diseases and Division of Geriatric Medicine, Department of Internal Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    Kidney Int 74:641-8. 2008
    ..We found that transient changes in renal function can occur following an annual zoledronic acid infusion but, in the long term, renal function was not different from control patients...
  22. ncbi Bone and muscle protective potential of the prostate-sparing synthetic androgen 7alpha-methyl-19-nortestosterone: evidence from the aged orchidectomized male rat model
    Katrien Venken
    Laboratory for Experimental Medicine and Endocrinology, Onderwijs en Navorsing, Campus Gasthuisberg, Leuven, Belgium
    Bone 36:663-70. 2005
    ..Our findings support the need for human studies to explore the potential of MENT as an option for androgen replacement in aging men...
  23. pmc Translation and adaption of the interRAI Suite to local requirements in Belgian hospitals
    Nathalie I H Wellens
    Center for Health Services and Nursing Research, Kapucijnenvoer 35 PB 7001 4, B 3000, Leuven, Belgium
    BMC Geriatr 12:53. 2012
    ..Our aim in this study was to translate and adapt the interRAI AC to the Belgian hospital context, where it can be used together with the interRAI Home Care (HC) and the interRAI Long Term Care Facility (LTCF)...
  24. doi Assessment of the relationship between age and the effect of risedronate treatment in women with postmenopausal osteoporosis: a pooled analysis of four studies
    Steven Boonen
    Bone Research Unit, Department of Experimental Medicine, Leuven University, Leuven, Belgium
    J Am Geriatr Soc 58:658-63. 2010
    ..To quantify the effect of age on the incidence of osteoporosis-related fractures and of risedronate treatment on fracture risk in different age groups in women with postmenopausal osteoporosis...
  25. doi Effect of an inpatient geriatric consultation team on functional outcome, mortality, institutionalization, and readmission rate in older adults with hip fracture: a controlled trial
    Mieke Deschodt
    Center for Health Services and Nursing Research, Katholieke Universiteit Leuven, Leuven, Belgium
    J Am Geriatr Soc 59:1299-308. 2011
    ..To evaluate the effect of an inpatient geriatric consultation team (IGCT) on end points of interest in people with hip fracture: length of stay, functional status, mortality, new nursing home admission, and hospital readmission...
  26. doi Sex steroids and the male skeleton: a tale of two hormones
    Filip Callewaert
    Department of Experimental Medicine, Katholieke Universiteit Leuven, Center for Musculoskeletal Research, Leuven University, Herestraat 49, B 3000 Belgium
    Trends Endocrinol Metab 21:89-95. 2010
    ..In fact, bone loss and fracture risk have been associated with estrogen exposure in elderly men. Overall, a compelling body of evidence suggests that both androgens and estrogens are crucial for male skeletal growth and maintenance...
  27. ncbi Impact of whole-body vibration training versus fitness training on muscle strength and muscle mass in older men: a 1-year randomized controlled trial
    An Bogaerts
    Division of Musculoskeletal Rehabilitation, Katholieke Universiteit Leuven, Tervuursevest 101, Leuven, Belgium
    J Gerontol A Biol Sci Med Sci 62:630-5. 2007
    ..This randomized controlled study investigated the effects of 1-year whole-body vibration (WBV) training on isometric and explosive muscle strength and muscle mass in community-dwelling men older than 60 years...
  28. doi Long-term impact of strength training on muscle strength characteristics in older adults
    Eva Kennis
    Physical Activity, Sports and Health Research Group, Department of Kinesiology, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, Belgium
    Arch Phys Med Rehabil 94:2054-60. 2013
    ..To evaluate the long-term preventive impact of strength training on muscle performance in older adults...
  29. pmc The interRAI Acute Care instrument incorporated in an eHealth system for standardized and web-based geriatric assessment: strengths, weaknesses, opportunities and threats in the acute hospital setting
    Els Devriendt
    Department of Public Health and Primary Care, Health Services and Nursing Research, KU Leuven, Kapucijnenvoer 35, 4th Floor, Leuven, 3000, Belgium
    BMC Geriatr 13:90. 2013
    ..The purpose of the study is to evaluate the (dis)advantages of the implementation of the interRAI Acute Care instrument as a comprehensive geriatric assessment instrument in an acute hospital context...
  30. doi Content validity and internal consistency of the Dutch translation of the Safety Attitudes Questionnaire: an observational study
    Els Devriendt
    Center for Health Services and Nursing Research, Katholieke Universiteit Leuven, Leuven, Belgium
    Int J Nurs Stud 49:327-37. 2012
    ..The Safety Attitudes Questionnaire is a validated, widely used instrument to investigate multiple dimensions of safety climate at the clinical level in a variety of inpatient and outpatient settings...
  31. ncbi Screening for risk of unplanned readmission in older patients admitted to hospital: predictive accuracy of three instruments
    Tom Braes
    Centre for Health Services and Nursing Research, Katholieke Universiteit Leuven, Leuven, Belgium
    Aging Clin Exp Res 22:345-51. 2010
    ..We compared the predictive accuracy of the Identification of Seniors at Risk (ISAR), the Flemish version of the Triage Risk Screening Tool (TRST) and Variable Indicative of Placement risk (VIP) in assessing unplanned readmissions...
  32. ncbi Reversing sex steroid deficiency and optimizing skeletal development in the adolescent with gonadal failure
    Dirk Vanderschueren
    Laboratory for Experimental Medicine and Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium
    Endocr Dev 8:150-65. 2005
    ..Replacing sex steroids according to a biphasic pattern (starting at low doses and ending at high-normal doses) seems the safest approach to reach targeted height and to optimize bone development...
  33. doi Once-weekly risedronate in men with osteoporosis: results of a 2-year, placebo-controlled, double-blind, multicenter study
    Steven Boonen
    Leuven University Center for Metabolic Bone Diseases, Division of Geriatric Medicine, University Hospitals Leuven, Leuven, Belgium
    J Bone Miner Res 24:719-25. 2009
    ..The effects of risedronate treatment on BMD and BTMs in this study were similar to those previously shown to be associated with fracture risk reductions in women with postmenopausal osteoporosis...
  34. doi Skeletal sexual dimorphism: relative contribution of sex steroids, GH-IGF1, and mechanical loading
    Filip Callewaert
    Center for Musculoskeletal Research, Department of Experimental Medicine, Katholieke Universiteit Leuven, Herestraat 49, B 3000 Leuven, Belgium
    J Endocrinol 207:127-34. 2010
    ....
  35. doi Postmenopausal osteoporosis treatment with antiresorptives: effects of discontinuation or long-term continuation on bone turnover and fracture risk--a perspective
    Steven Boonen
    Leuven University Center for Metabolic Bone Diseases, Katholieke Universiteit Leuven, Leuven, Belgium
    J Bone Miner Res 27:963-74. 2012
    ..In the absence of this, a clinical recommendation for physicians may be to periodically assess the benefits/risks of continuation versus discontinuation versus alternative management strategies...
  36. doi Sequential therapy in the treatment of osteoporosis
    Steven Boonen
    Katholieke Universiteit Leuven, Centre for Metabolic Bone Diseases, and Division of Geriatric Medicine, Leuven, Belgium
    Curr Med Res Opin 27:1149-55. 2011
    ..To review the clinical data in the sequential use of antiresorptive and anabolic agents for the treatment of osteoporosis...
  37. ncbi Identifying postmenopausal women with osteoporosis by calcaneal ultrasound, metacarpal digital X-ray radiogrammetry and phalangeal radiographic absorptiometry: a comparative study
    Steven Boonen
    Leuven University Center for Metabolic Bone Diseases, Universitaire Ziekenhuizen K U Leuven, Herestraat 49, B 3000, Leuven, Belgium
    Osteoporos Int 16:93-100. 2005
    ..These data suggest that metacarpal DXR and phalangeal RA may be as effective as calcaneal QUS for targeting DXA testing in high-risk postmenopausal women...
  38. doi The effectiveness of inpatient geriatric evaluation and management units: a systematic review and meta-analysis
    Katleen Van Craen
    Center for Health Services and Nursing Research, Katholieke Universiteit Leuven, Leuven, Belgium
    J Am Geriatr Soc 58:83-92. 2010
    ..To examine how geriatric evaluation and management units (GEMUs) are organized and to examine the effectiveness of admission on a GEMU...
  39. ncbi Fracture protection in osteoporosis with risedronate
    Steven Boonen
    Leuven University Center for Metabolic Bone Diseases, Katholieke Universiteit Leuven, Leuven, Belgium
    Hosp Med 65:535-40. 2004
  40. doi Gonadal sex steroid status and bone health in middle-aged and elderly European men
    D Vanderschueren
    Department of Andrology and Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium
    Osteoporos Int 21:1331-9. 2010
    ..Higher free and total E(2) though not testosterone, were independently associated with higher QUS parameters...
  41. ncbi Estrogens are essential for male pubertal periosteal bone expansion
    Roger Bouillon
    Division of Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium
    J Clin Endocrinol Metab 89:6025-9. 2004
    ..These findings demonstrate that androgens alone are insufficient, whereas estrogens are essential for the process of pubertal periosteal bone expansion typically associated with the male bone phenotype...
  42. doi Nursing staff attitudes of hip protector use in long-term care, and differences in characteristics between adherent and non-adherent residents: a survey and observational study
    Koen Milisen
    Center for Health Services and Nursing Research, Katholieke Universiteit Leuven, Leuven, Belgium
    Int J Nurs Stud 48:193-203. 2011
    ..A major problem in studying the effectiveness of hip protectors is residents' poor adherence. In nursing homes, adherence is dependent not only on the resident, but also on staff knowledge of and attitudes about hip protectors...
  43. doi Transmission of whole-body vibration and its effect on muscle activation
    Ekaterina Tankisheva
    Department of Rehabilitation Science, Research Centre for Musculoskeletal Rehabilitation, Katholieke Universiteit Leuven, Leuven, Belgium
    J Strength Cond Res 27:2533-41. 2013
    ..Moreover, the present results contribute to optimize the most advantageous whole-body vibration protocol and to determine the beneficial effects on muscle and bone...
  44. doi Androgens and skeletal muscle: cellular and molecular action mechanisms underlying the anabolic actions
    Vanessa Dubois
    Molecular Endocrinology Laboratory, Department of Molecular Cell Biology, K U Leuven, Campus Gasthuisberg, O and N1, Herestraat 49, Leuven, Belgium
    Cell Mol Life Sci 69:1651-67. 2012
    ..In conclusion, the anabolic effect of androgens on skeletal muscle is not only explained by activation of the myocyte androgen receptor but is also the combined result of many genomic and non-genomic actions...
  45. pmc 1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase
    Carsten Kriebitzsch
    Laboratory for Experimental Medicine and Endocrinology LEGENDO, Catholic University of Leuven, Leuven, Belgium
    J Bone Miner Res 26:2991-3000. 2011
    ..In conclusion, this study showed that cbs is a primary 1,25(OH)(2) D(3) target gene which renders HCY metabolism responsive to 1,25(OH)(2) D(3)...
  46. ncbi Addressing and meeting the needs of osteoporotic patients with strontium ranelate: a review
    Steven Boonen
    Leuven University Center for Metabolic Bone Diseases, Katholieke Universiteit Leuven, Leuven, Belgium
    Curr Opin Rheumatol 18:S21-7. 2006
    ..Together with the antifracture data, the clinical benefits and quality of life data endorse the treatment of postmenopausal osteoporosis with strontium ranelate...
  47. doi Osteoporosis management: impact of fracture type on cost and quality of life in patients at risk for fracture I
    Steven Boonen
    Leuven University Center for Metabolic Bone Diseases and Division of Geriatric Medicine, Leuven, Belgium
    Curr Med Res Opin 24:1781-8. 2008
    ..It is a chronic disease in which fracture is the main outcome, and the impact of these fractures can vary depending on the age of the individual and the severity of the fracture...
  48. ncbi Androgens and bone
    Dirk Vanderschueren
    Laboratory for Experimental Medicine and Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium
    Endocr Rev 25:389-425. 2004
    ..In conclusion, androgens may protect men against osteoporosis via maintenance of cancellous bone mass and expansion of cortical bone. Such androgen action on bone is mediated by the AR and ERalpha...
  49. doi Vitamin D deficiency and chronic obstructive pulmonary disease: a vicious circle
    Wim Janssens
    Respiratory Division, University of Leuven, Leuven, Belgium
    Vitam Horm 86:379-99. 2011
    ..The burning question in COPD is whether prevention of vitamin D deficiency or adequate supplementation may reverse the natural course of the disease...
  50. doi Balloon kyphoplasty for the treatment of acute vertebral compression fractures: 2-year results from a randomized trial
    Steven Boonen
    Leuven University Division of Geriatric Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    J Bone Miner Res 26:1627-37. 2011
    ..Most outcomes are not statistically different at 24 months, but the reduction in back pain remains statistically significant at all time points...
  51. ncbi Evidence-based guidelines for the treatment of postmenopausal osteoporosis: a consensus document of the Belgian Bone Club
    Steven Boonen
    Center for Metabolic Bone Diseases, Katholieke University Leuven, Leuven, Belgium
    Osteoporos Int 16:239-54. 2005
  52. pmc The genomic landscape of prostate cancer
    Lien Spans
    Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, University of Leuven, Campus Gasthuisberg, Herestraat 49, P O Box 901, 3000 Leuven, Belgium
    Int J Mol Sci 14:10822-51. 2013
    ..The present review summarizes current knowledge on copy number changes, gene fusions, single nucleotide mutations and polymorphisms, methylation, microRNAs and long non-coding RNAs obtained from high-throughput studies...
  53. ncbi Functional outcome and quality of life following hip fracture in elderly women: a prospective controlled study
    Steven Boonen
    Leuven University Center for Metabolic Bone Diseases and Division of Geriatric Medicine, Katholieke Universiteit Leuven, Herestraat 49, B 3000, Leuven, Belgium
    Osteoporos Int 15:87-94. 2004
    ..Function upon hospital discharge is the strongest predictor of functional status 1 year later. Assessing QoL in hip fracture women through self-administered questionnaires is subject to considerable bias due to non-response...
  54. doi The correlation between the SOS in trabecular bone and stiffness and density studied by finite-element analysis
    Liesbet Goossens
    Division of Biomechanics and Engineering Design, Department of Mechanical Engineering, K U Leuven, Leuven, Belgium
    IEEE Trans Ultrason Ferroelectr Freq Control 55:1234-42. 2008
    ....
  55. ncbi Effect of 6-month whole body vibration training on hip density, muscle strength, and postural control in postmenopausal women: a randomized controlled pilot study
    Sabine M P Verschueren
    Laboratory of Motor Control, Department of Kinesiology, Faculteit Lichamelijke Opvoeding en Kinesitherapie, Katholieke Universiteit, Leuven, Belgium
    J Bone Miner Res 19:352-9. 2004
    ..Vibration training significantly increased BMD of the hip. These findings suggest that WBV training might be useful in the prevention of osteoporosis...
  56. pmc The impact of care pathways for patients with proximal femur fracture: rationale and design of a cluster-randomized controlled trial
    Kris Vanhaecht
    Health Services Research Group, School of Public Health, KU Leuven, University of Leuven, Kapucijnenvoer 35, 3000, Leuven, Belgium
    BMC Health Serv Res 12:124. 2012
    ....
  57. ncbi Fall prediction in inpatients by bedside nurses using the St. Thomas's Risk Assessment Tool in Falling Elderly Inpatients (STRATIFY) instrument: a multicenter study
    Koen Milisen
    Center for Health Services and Nursing Research, Department for Geriatric Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    J Am Geriatr Soc 55:725-33. 2007
    ..To assess the predictive value of the St. Thomas's Risk Assessment Tool in Falling Elderly Inpatients (STRATIFY) instrument, a simple fall-risk assessment tool, when administered at a patient's hospital bedside by nurses...